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4781“…Leishmaniasis is a protozoal disease of human that occurs in most parts of the world. …”
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4782por Stephens, Christopher R., Heau, Joaquín Giménez, González, Camila, Ibarra-Cerdeña, Carlos N., Sánchez-Cordero, Victor, González-Salazar, Constantino“…We illustrate the general methodology by considering an important emerging disease - Leishmaniasis. This data mining methodology allows for the use of geographic data to construct inferential biotic interaction networks which can then be used to build prediction models with a wide range of applications in ecology, biodiversity and emerging diseases.…”
Publicado 2009
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4783por Soares, Rodrigo P., Margonari, Carina, Secundino, Nágila C., Macêdo, Maria E., da Costa, Simone M., Rangel, Elizabeth F., Pimenta, Paulo F., Turco, Salvatore J.“…The epidemiological relevance of L. whitmani as a vector of American Cutaneous Leishmaniasis (ACL) in Brazil is discussed.…”
Publicado 2010
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4784por Gurvitz, Aner“…Leishmania major causes leishmaniasis and is grouped within the Trypanosomatidae family, which also includes the etiologic agent for African sleeping sickness, Trypanosoma brucei. …”
Publicado 2009
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4785por Moore, Benjamin, Miles, Andrew J., Guerra-Giraldez, Cristina, Simpson, Peter, Iwata, Momi, Wallace, B. A., Matthews, Stephen J., Smith, Deborah F., Brown, Katherine A.“…The 57-residue small hydrophilic endoplasmic reticulum-associated protein (SHERP) shows highly specific, stage-regulated expression in the non-replicative vector-transmitted stages of the kinetoplastid parasite, Leishmania major, the causative agent of human cutaneous leishmaniasis. Previous studies have demonstrated that SHERP localizes as a peripheral membrane protein on the cytosolic face of the endoplasmic reticulum and on outer mitochondrial membranes, whereas its high copy number suggests a critical function in vivo. …”
Publicado 2011
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4786por Trópia de Abreu, Raquel, Carvalho, Maria das Graças, Carneiro, Cláudia Martins, Giunchetti, Rodolfo Cordeiro, Teixeira-Carvalho, Andréa, Martins-Filho, Olindo Assis, Coura-Vital, Wendel, Corrêa-Oliveira, Rodrigo, Reis, Alexandre Barbosa“…BACKGROUND: The bone marrow is considered to be an important storage of parasites in Leishmania-infected dogs, although little is known about cellular genesis in this organ during canine visceral leishmaniasis (CVL). METHODOLOGY/PRINCIPAL FINDINGS: The aim of the present study was to evaluate changes in erythropoiesis and leucopoiesis in bone marrow aspirates from dogs naturally infected with Leishmania chagasi and presenting different clinical statuses and bone marrow parasite densities. …”
Publicado 2011
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4787“…Protozoan parasites cause serious human and zoonotic infections, including life-threatening diseases such as malaria, African and American trypanosomiasis, and leishmaniasis. These diseases are no more common in the developed world, but together they still threaten about 40% of the world population (WHO estimates). …”
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4788por Ostyn, Bart, Gidwani, Kamlesh, Khanal, Basudha, Picado, Albert, Chappuis, François, Singh, Shri Prakash, Rijal, Suman, Sundar, Shyam, Boelaert, Marleen“…Incidence of Leishmania donovani infection and Visceral Leishmaniasis (VL) was assessed in a prospective study in Indian and Nepalese high-endemic villages. …”
Publicado 2011
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4789por Stanley, Amanda C., de Labastida Rivera, Fabian, Haque, Ashraful, Sheel, Meru, Zhou, Yonghong, Amante, Fiona H., Bunn, Patrick T., Randall, Louise M., Pfeffer, Klaus, Scheu, Stefanie, Hickey, Michael J., Saunders, Bernadette M., Ware, Carl, Hill, Geoff R., Tamada, Koji, Kaye, Paul M., Engwerda, Christian R.“…We found that LIGHT is critical for control of hepatic parasite growth in mice with visceral leishmaniasis (VL) caused by infection with the protozoan parasite Leishmania donovani. …”
Publicado 2011
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4790por Coelho, Adriano C., Boisvert, Sébastien, Mukherjee, Angana, Leprohon, Philippe, Corbeil, Jacques, Ouellette, Marc“…BACKGROUND: Miltefosine (MF) is the first oral compound used in the chemotherapy against leishmaniasis. Since the mechanism of action of this drug and the targets of MF in Leishmania are unclear, we generated in a step-by-step manner Leishmania major promastigote mutants highly resistant to MF. …”
Publicado 2012
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4791“…With the introduction of highly active anti-retroviral therapy (HAART), cryptosporidiosis, leishmaniasis, schistosomiasis, strongyloidiasis, and toxoplasmosis are among parasitic diseases reported in association with immune reconstitution inflammatory syndrome (IRIS). …”
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4792por Soflaei, Saied, Dalimi, Abdolhossein, Ghaffarifar, Fatemeh, Shakibaie, Mojtaba, Shahverdi, Ahmad Reza, Shafiepour, Mohsen“…Visceral leishmaniasis is one of the most important sever diseases in tropical and subtropical countries. …”
Publicado 2012
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4793por Britta, Elizandra Aparecida, Barbosa Silva, Ana Paula, Ueda-Nakamura, Tânia, Dias-Filho, Benedito Prado, Silva, Cleuza Conceição, Sernaglia, Rosana Lázara, Nakamura, Celso Vataru“…BACKGROUND: Leishmaniasis is a major health problem that affects more than 12 million people. …”
Publicado 2012
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4794por Hernández-Montes, Omar, González Guzmán, Saúl, Martínez Gómez, Federico, Barker, Douglas C., Monroy-Ostria, Amalia“…(Leishmania) mexicana to look for genetic differences between strains isolated from patients with diffuse cutaneous (DCL) and localized (LCL) leishmaniasis. The kDNA was analyzed using polymerase chain reaction (PCR), restriction fragment polymorphism analysis of the PCR products (PCR-RFLP) and the PCR products were sequenced. …”
Publicado 2012
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4795por Mahmoudzadeh-Niknam, Hamid, Khalili, Ghader, Abrishami, Firoozeh, Najafy, Ali, Khaze, Vahid“…Leishmania tropica is one of the causative agents of leishmaniasis in humans. Routes of infection have been reported to be an important variable for some species of Leishmania parasites. …”
Publicado 2013
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4796por Sazgarnia, Ameneh, Zabolinejad, Naghmeh, Layegh, Pouran, Rajabi, Omid, Berenji, Fariba, Javidi, Zari, Salari, Roshanak“…OBJECTIVE(S): Cutaneous leishmaniasis is a common parasitic disease which is endemic in some parts of the world. …”
Publicado 2012
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4797por Barrera, Patricia, Sülsen, Valeria P., Lozano, Esteban, Rivera, Mónica, Beer, María Florencia, Tonn, Carlos, Martino, Virginia S., Sosa, Miguel A.“…Leishmaniasis is a worldwide parasitic disease, caused by monoflagellate parasites of the genus Leishmania. …”
Publicado 2013
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4798“…Sand fly salivary proteins are on the spotlight to become vaccine candidates against leishmaniasis and to markers of exposure to sand fly bites due to the host immune responses they elicit. …”
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4799por dos Reis, Matheus Balduíno Goncalves, Manjolin, Letícia Correa, Maquiaveli, Claudia do Carmo, Santos-Filho, Osvaldo Andrade, da Silva, Edson Roberto“…Due to the low IC(50) values obtained for ARG-L, flavanols can be used as a supplement for leishmaniasis treatment.…”
Publicado 2013
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4800por Bagher KHADEM ERFAN, Mohammad, MOHEBALI, Mehdi, KAZEMI-RAD, Elham, HAJJARAN, Homa, EDRISSIAN, GholamHossein, MAMISHI, Setareh, SAFFARi, Mojtaba, RAOOFIAN, Reza, HEIDARI, Mansour“…BACKGROUND: Pentavalent antimonials are the first line drugs for the treatment of leishmaniasis. Unresponsiveness of Leishmania spp. to antimonial drugs is a serious problem in some endemic areas. …”
Publicado 2013
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