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  1. 4881
    “…Here, we show the antileishmanial activity of DODAB nano-sized cationic bilayer fragments on stationary-phase promastigotes and amastigotes of Leishmania amazonensis, the causative agent of cutaneous leishmaniasis. Upon treatment with DODAB, we analyzed the parasite surface zeta-potential, parasite viability, cellular structural modifications, and intracellular proliferation. …”
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    Effect of DODAB Nano-Sized Cationic Bilayer Fragments against Leishmania amazonensis
  2. 4882
    “…[Image: see text] Visceral leishmaniasis (VL) is a parasitic infection that results in approximately 26 000–65 000 deaths annually. …”
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    Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent In Vitro Antileishmanial Activity: Initial SAR and Assessment of In Vivo Activity
  3. 4883
    “…In this paper, we identified and aligned the protein sequences of 28 different DEAD-box proteins from the kinetoplast-protozoan parasite Leishmania infantum, which is the cause of the visceral form of leishmaniasis that is often lethal if left untreated, and compared them with the consensus sequence derived from DEAD-box proteins in general, and from the Ded1/DDX3 subfamily in particular, from a wide variety of other organisms. …”
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    The In Silico Identification of Potential Members of the Ded1/DDX3 Subfamily of DEAD-Box RNA Helicases from the Protozoan Parasite Leishmania infantum and Their Analyses in Yeast
  4. 4884
    “…Conclusion: Our results suggest that due to their efficacy and selectivity against intracellular parasites and the potential mechanisms underlying their leishmanicidal effect, the compounds 18 and 22 could be used as tools for designing new chemotherapies against leishmaniasis.…”
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    Leishmanicidal Activity of Betulin Derivatives in Leishmania amazonensis; Effect on Plasma and Mitochondrial Membrane Potential, and Macrophage Nitric Oxide and Superoxide Production
  5. 4885
    “…Leishmaniasis is a vector-borne disease caused by the protozoan parasite Leishmania found in tropical and sub-tropical areas, affecting 12 million people around the world. …”
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    Alkyl-Resorcinol Derivatives as Inhibitors of GDP-Mannose Pyrophosphorylase with Antileishmanial Activities
  6. 4886
    “…Leishmaniasis are neglected diseases caused by several species of Leishmania that affect humans and many domestic and wild animals with a worldwide distribution. …”
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    A Systematic Review (1990–2021) of Wild Animals Infected with Zoonotic Leishmania
  7. 4887
    “…Leishmania is an intracellular protozoan parasite that causes a wide spectrum of diseases known as leishmaniasis. This parasite displays different strategies, including apoptosis inhibition, to down-regulate host cell defense mechanisms in order to perpetuate infection.…”
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    Leishmania: manipulation of signaling pathways to inhibit host cell apoptosis
  8. 4888
    “…We focused on understanding the role of the AMPs attacin (Att), cecropin (Cec), and four defensins (Def1, Def2, Def3, and Def4) in Lutzomyia longipalpis, the main vector of visceral leishmaniasis in the Americas. Larvae and adults were collected under different feeding regimens, in addition to females artificially infected by Leishmania infantum. …”
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    Lutzomyia longipalpis Antimicrobial Peptides: Differential Expression during Development and Potential Involvement in Vector Interaction with Microbiota and Leishmania
  9. 4889
    “…Current treatment options for visceral leishmaniasis have several drawbacks, and clinicians are confronted with an increasing number of treatment failures. …”
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    Identification of Resistance Determinants for a Promising Antileishmanial Oxaborole Series
  10. 4890
    “…Sodium antimonials are one of the major and common drugs used against visceral form leishmaniasis (VL). However, the development of drug resistance makes it difficult to manage this disease. …”
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    Modulation of Splenic B Cell Subsets during Experimental Leishmania donovani Infection in BALB/c Mice
  11. 4891
    “…The diagnostic procedures followed in these patients included: detailed medical history, clinical and histological examination, computed tomography and magnetic resonance imaging, laboratory findings (complete blood count, sedimentation rate, antinuclear antibody test, rheumatoid factor, venereal disease research laboratory test, leishmaniasis and fungal serology, antineutrophil cytoplasmic antibodies ANCA test), and chest X-ray. …”
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    Cocaine-Induced Midline Destructive Lesions (CIMDL): A Real Challenge in Diagnosis
  12. 4892
    “…We illustrate applicability of our method by applying data on various public health problems, including infectious diseases (Ebola, SARS, and Leishmaniasis) and social issues (obesity and alcohol drinking) to compute transmission rates over time. …”
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    Analytical Estimation of Data-Motivated Time-Dependent Disease Transmission Rate: An Application to Ebola and Selected Public Health Problems
  13. 4893
    “…Leishmaniasis is a debilitating disease of the tropics, subtropics and southern Europe caused by Leishmania parasites that are transmitted during blood feeding by phlebotomine sand flies (Diptera: Psychodidae). …”
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    Micro-CT visualization of a promastigote secretory gel (PSG) and parasite plug in the digestive tract of the sand fly Lutzomyia longipalpis infected with Leishmania mexicana
  14. 4894
    “…Selenium and their derivatives have emerged as an interesting strategy for the treatment of different prozotoan diseases, such as African trypanosomiasis, leishmaniasis, and malaria. In the case of Chagas disease, diverse selenium scaffolds have been reported with antichagasic activity in vitro and in vivo. …”
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    Selenium Derivatives as Promising Therapy for Chagas Disease: In Vitro and In Vivo Studies
  15. 4895
    “…Leishmaniasis is a neglected disease that affects 12 million people living mainly in developing countries. …”
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    Design, synthesis and biological evaluation of N-oxide derivatives with potent in vivo antileishmanial activity
  16. 4896
    “…Leishmaniasis is a neglected tropical disease caused by Leishmania spp. …”
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    In Leishmania major, the Homolog of the Oncogene PES1 May Play a Critical Role in Parasite Infectivity
  17. 4897
    “…Phlebotomus papatasi is the vector of Leishmania major, causing cutaneous leishmaniasis in the Old World. We investigated whether P. papatasi immunity genes were expressed toward L. major, commensal gut microbes, or a combination of both. …”
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    Phlebotomus papatasi Antimicrobial Peptides in Larvae and Females and a Gut-Specific Defensin Upregulated by Leishmania major Infection
  18. 4898
    “…The Leishmania donovani species complex is the causative agent of visceral leishmaniasis, which cause 20–40,000 fatalities a year. …”
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    Candidates for Balancing Selection in Leishmania donovani Complex Parasites
  19. 4899
    por Mackay, Alison M.
    Publicado 2022
    “…Daylight PDT may find broader antimicrobial applications than just Acne and Cutaneous Leishmaniasis, and Ambulatory PDT devices could become popular in regions where resources are limited or daylight exposure is not possible or inappropriate. …”
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    The evolution of clinical guidelines for antimicrobial photodynamic therapy of skin
  20. 4900
    “…Leishmania donovani, the causative agent of visceral leishmaniasis, infects and resides within tissue macrophage cells. …”
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    Leishmania survives by exporting miR-146a from infected to resident cells to subjugate inflammation
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