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4961por Lage, Paula Sousa, de Andrade, Pedro Henrique Rocha, Lopes, Amanda de Santana, Chávez Fumagalli, Miguel Angel, Valadares, Diogo Garcia, Duarte, Mariana Costa, Pagliara Lage, Daniela, Costa, Lourena Emanuele, Martins, Vivian Tamietti, Ribeiro, Tatiana Gomes, Filho, José Dias de Souza, Tavares, Carlos Alberto Pereira, de Pádua, Rodrigo Maia, Leite, João Paulo Viana, Coelho, Eduardo Antonio Ferraz“…The development of new and cost-effective alternative therapeutic strategies to treat leishmaniasis has become a high priority. In the present study, the antileishmanial activity of Strychnos pseudoquina St. …”
Publicado 2013
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4962por Vincent, Isabel M., Weidt, Stefan, Rivas, Luis, Burgess, Karl, Smith, Terry K., Ouellette, Marc“…A detailed knowledge of the mode of action of miltefosine will be important to inform the design of combination therapies to combat leishmaniasis, something that the research community should be prioritising in the coming years.…”
Publicado 2013
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4963por Rodrigues, Ana Paula D., Farias, Luis Henrique S., Carvalho, Antonio Sérgio C., Santos, Alberdan S., do Nascimento, José Luiz M., Silva, Edilene O.“…Chemotherapy is one of the most effective treatments for Leishmaniasis. However, the drugs available are expensive, invasive, require long-term treatment and have severe side effects. …”
Publicado 2014
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4964por Borborema, Samanta Etel Treiger, Osso, João Alberto, de Andrade, Heitor Franco, do Nascimento, Nanci“…Pentavalent antimonials such as meglumine antimoniate (MA) are the primary treatments for leishmaniasis, a complex disease caused by protozoan parasites of the genus Leishmania . …”
Publicado 2013
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4965por Trujillo, Adolfo Vásquez, Reina, Angélica E González, Orjuela, Agustín Góngora, Suárez, Edgar Prieto, Palomares, Jairo Enrique, Alvarez, Luz Stella Buitrago“…Lutzomyia antunesi has been commonly reported in outbreaks of cutaneous leishmaniasis (CL) in the Orinoquia region of Colombia. …”
Publicado 2013
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4966por Rodrigues, Igor A., Azevedo, Mariana M. B., Chaves, Francisco C. M., Alviano, Celuta S., Alviano, Daniela S., Vermelho, Alane B.“…Currently available leishmaniasis treatments are limited due to severe side effects. …”
Publicado 2014
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4967por Celeste, Beatriz Julieta, Arroyo Sanchez, Maria Carmen, Ramos-Sanchez, Eduardo Milton, Castro, Luiz Guilherme M., Lima Costa, Francisco Assis, Goto, Hiro“…ELISA-rHsp83 was significantly more sensitive than ELISA–L. major-like when considering either CL/ML (P = 0.041) or all leishmaniasis patients (P = 0.013). When samples from other infectious disease patients were evaluated for cross-reactivity, ELISA-rHsp83 was more specific than ELISA–L. major-like, specifically for Chagas disease samples (P < 0.001). …”
Publicado 2014
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4968“…Leishmaniasis is an important parasitic problem and is in focus for development of new drugs all over the world. …”
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4969“…In this paper, we aim to systematically analyze the effectiveness of community based interventions (CBI) for the prevention and control of non-helminthic diseases including dengue, trypanosomiasis, chagas, leishmaniasis, buruli ulcer, leprosy and trachoma. We systematically reviewed literature published up to May 2013 and included 62 studies in this review. …”
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4970por Cruz-Chan, Julio Vladimir, Carmen Aguilar-Cetina, Amarú del, Estefanía Villanueva-Lizama, Liliana, Pablo Martínez-Vega, Pedro, Jesús Ramírez-Sierra, Maria, Enrique Rosado-Vallado, Miguel, Leonardo Guillermo-Cordero, José, Dumonteil, Eric“…BACKGROUND: Cutaneous leishmaniasis is a tropical disease affecting over one million patients annually and Leishmania (L.) mexicana is one of the major etiological agents in the Americas. …”
Publicado 2014
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4971por Ghawar, Wissem, Attia, Hanène, Bettaieb, Jihene, Yazidi, Rihab, Laouini, Dhafer, Salah, Afif Ben“…Zoonotic cutaneous leishmaniasis (ZCL) caused by Leishmania (L.) major parasites represents a major health problem with a large spectrum of clinical manifestations. …”
Publicado 2014
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4972por M.H, Branquinha, F.A, Marinho, L.S, Sangenito, S.S.C, Oliveira, K.C, Gonçalves, V, Ennes-Vidal, C.M, d’Avila-Levy, A.L.S, Santos“…The treatment for both leishmaniasis and trypanosomiasis, which are severe human infections caused by trypanosomatids belonging to Leishmania and Trypanosoma genera, respectively, is extremely limited because of concerns of toxicity and efficacy with the available anti-protozoan drugs, as well as the emergence of drug resistance. …”
Publicado 2013
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4973“…Cutaneous leishmaniasis has various phenotypic aspects consisting of polymorphic amastigotes with different genetic ranges. …”
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4974por Sacramento, Laís Amorim, Cunha, Fernando Q., de Almeida, Roque Pacheco, da Silva, João Santana, Carregaro, Vanessa“…Visceral leishmaniasis (VL) is a chronic and fatal disease caused by Leishmania infantum in Brazil. …”
Publicado 2014
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4975por de Brito, Veruska Nogueira, de Almeida, Arleana do Bom Parto Ferreira, Nakazato, Luciano, Duarte, Rosemere, Souza, Cladson de Oliveira, Sousa, Valéria Régia Franco“…Visceral leishmaniasis (VL) in Brazil is transmitted by the phlebotomine Lutzomyia longipalpis and in some midwestern regions by Lutzomyia cruzi. …”
Publicado 2014
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4976“…Pigmentary disorders, photodermatoses, leishmaniasis and skin tumors were found to be more prevalent in this region. …”
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4977por Pestehchian, Nader, Etemadifarr, Masoud, Yousefi, Hossein-Ali, Chiani, Maryam, Aslani, Neda, Nasr, Zahra“…Given the high prevalence of cutaneous leishmaniasis in Isfahan, all the participants were also examined for protozoan leishmania microscopically. …”
Publicado 2014
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4978por da Luz, João S. B., de Oliveira, Erwelly B., Martins, Monica C. B., da Silva, Nicácio H., Alves, Luiz C., dos Santos, Fábio A. B., da Silva, Luiz L. S., Silva, Eliete C., de Medeiros, Paloma L.“…Leishmaniasis is considered by the World Health Organization as one of the infectious parasitic diseases endemic of great relevance and a global public health problem. …”
Publicado 2015
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4979por Ezatpour, Behrouz, Saedi Dezaki, Ebrahim, Mahmoudvand, Hossein, Azadpour, Mojgan, Ezzatkhah, Fatemeh“…This extract (0–100 µg/mL) was evaluated in vitro against promastigote and intracellular amastigote forms of L. tropica (MRHO/IR/75/ER) and then tested on cutaneous leishmaniasis (CL) in male BALB/c mice with L. major to reproduce the antileishmanial activity topically. …”
Publicado 2015
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4980por Adel, Amel, Abatih, Emmanuel, Speybroeck, Niko, Soukehal, Abdelkrim, Bouguedour, Rachid, Boughalem, Karim, Bouhbal, Abdelmalek, Djerbal, Mouloud, Saegerman, Claude, Berkvens, Dirk“…A concordance between the present results and the incidence of human cases of visceral leishmaniasis was observed, where also a maximum was recorded for Bejaia. …”
Publicado 2015
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