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5141por Hurrell, Benjamin P., Schuster, Steffen, Grün, Eva, Coutaz, Manuel, Williams, Roderick A., Held, Werner, Malissen, Bernard, Malissen, Marie, Yousefi, Shida, Simon, Hans-Uwe, Müller, Andreas J., Tacchini-Cottier, Fabienne“…Our data thus demonstrate an unanticipated negative role for these innate immune cells in host defense, suggesting that in certain forms of cutaneous leishmaniasis, regulating neutrophil recruitment could be a strategy to promote lesion healing.…”
Publicado 2015
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5142por RAKHSHANPOUR, Arash, MOHEBALI, Mehdi, AKHONDI, Behnaz, RAHIMI, Mohammad Taghi, ROKNI, Mohammad Bagher“…BACKGROUND: Visceral leishmaniasis (VL) or kala-azar is considered as a parasitic disease caused by the species of Leishmania donovani complex which is intracellular parasites. …”
Publicado 2014
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5143por Kaur, Harparkash, Seifert, Karin, Hawkes, Geoffrey E., Coumbarides, Gregory S., Alvar, Jorge, Croft, Simon L.“…Miltefosine, an effective oral treatment of visceral leishmaniasis (VL), was selected in May 2005, by the governments of India, Nepal, and Bangladesh for the elimination of VL. …”
Publicado 2015
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5144por Yazidi, Rihab, Bettaieb, Jihene, Ghawar, Wissem, Jaouadi, Kaouther, Châabane, Sana, Zaatour, Amor, Ben Salah, Afif“…BACKGROUND: Zoonotic cutaneous leishmaniasis caused by Leishmania (L.) major is endemoepidemic in the Center and South of Tunisia. …”
Publicado 2015
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5145por Dillon, Laura A. L., Okrah, Kwame, Hughitt, V. Keith, Suresh, Rahul, Li, Yuan, Fernandes, Maria Cecilia, Belew, A. Trey, Corrada Bravo, Hector, Mosser, David M., El-Sayed, Najib M.“…Protozoan parasites of the genus Leishmania are the etiological agents of leishmaniasis, a group of diseases with a worldwide incidence of 0.9–1.6 million cases per year. …”
Publicado 2015
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5146por Harrabi, Myriam, Bettaieb, Jihène, Ghawar, Wissem, Toumi, Amine, Zaâtour, Amor, Yazidi, Rihab, Chaâbane, Sana, Chalghaf, Bilel, Hide, Mallorie, Bañuls, Anne-Laure, Ben Salah, Afif“…In Tunisia, cases of zoonotic cutaneous leishmaniasis caused by Leishmania major are increasing and spreading from the south-west to new areas in the center. …”
Publicado 2015
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5147“…OBJECTIVE(S): Cutaneous Leishmaniasis (CL) is a parasitic disease caused by various species of the flagellated protozoan, Leishmania. …”
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5148por Gogulamudi, Venkateswara Reddy, Dubey, Mohan Lal, Kaul, Deepak, Atluri, Venkata Subba Rao, Sehgal, Rakesh“…Our study is the first to highlight the important role of the TACO gene in Leishmania entry, survival and to identify TACO gene downregulation as potential drug target against leishmaniasis.…”
Publicado 2015
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5149“…OBJECTIVE(S): Cutaneous Leishmaniasis is a common and endemic disease in Khorasan province in North-East of Iran. …”
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5150por Aguiar, Anna CC, Cunha, Ananda C, Ceravolo, Isabela Penna, Gonçalves, Regina A Correia, Oliveira, Arildo JB, Krettli, Antoniana Ursine“…Several species of Aspidosperma plants are used to treat diseases in the tropics, including Aspidosperma ramiflorum, which acts against leishmaniasis, an activity that is experimentally confirmed. …”
Publicado 2015
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5151por BARATI, Mohammad, MOHEBALI, Mehdi, ALIMOHAMMADIAN, Mohammad Hossein, KHMESIPOUR, Ali, KESHAVARZ, Hossein, AKHOUNDI, Behnaz, ZAREI, Zabihollah“…Background: Canine visceral leishmaniasis (CVL) is not only an emerging veterinary concern but also a public health threat in endemic areas. …”
Publicado 2015
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5152por Cauwelaert, Natasha Dubois, Desbien, Anthony L., Hudson, Thomas E., Pine, Samuel O., Reed, Steven G., Coler, Rhea N., Orr, Mark T.“…This enhanced immunity is sufficient to provide protection against many diseases including tuberculosis and leishmaniasis. To better characterize the adjuvant action it is important to understand how the different cytokines and transcription factors contribute to the initiation of immunity. …”
Publicado 2016
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5153por Agallou, Maria, Athanasiou, Evita, Samiotaki, Martina, Panayotou, George, Karagouni, Evdokia“…Leishmania infantum is the etiologic agent of zoonotic visceral leishmaniasis (VL) in countries in the Mediterranean basin, where dogs are the domestic reservoirs and represent important elements in the transmission of the disease. …”
Publicado 2016
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5154por Joshi, Sumit, Yadav, Narendra K., Rawat, Keerti, Tripathi, Chandra Dev P., Jaiswal, Anil K., Khare, Prashant, Tandon, Rati, Baharia, Rajendra K., Das, Sanchita, Gupta, Reema, Kushawaha, Pramod K., Sundar, Shyam, Sahasrabuddhe, Amogh A., Dube, Anuradha“…Our prior studies demonstrated that cellular response of T helper 1 (Th1) type was generated by a soluble antigenic fraction (ranging from 89.9 to 97.1 kDa) of Leishmania donovani promastigote, in treated Leishmania patients as well as hamsters and showed significant prophylactic potential against experimental visceral leishmaniasis (VL). Eighteen Th1 stimulatory proteins were identified through proteomic analysis of this subfraction, out of which 15 were developed as recombinant proteins. …”
Publicado 2016
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5155por Ravensbergen, Sofanne J., Lokate, Mariëtte, Cornish, Darren, Kloeze, Eveline, Ott, Alewijn, Friedrich, Alex W., van Hest, Rob, Akkerman, Onno W., de Lange, Wiel C., van der Werf, Tjip S., Bathoorn, Erik, Stienstra, Ymkje“…Patients also reported with diseases which are less common—e.g. leishmaniasis, or even conditions rarely diagnosed in Europe—e.g. louse borne relapsing fever. …”
Publicado 2016
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5156por LOPES, Estela Gallucci, GERALDO, Carlos Alberto, MARCILI, Arlei, SILVA, Ricardo Duarte, KEID, Lara Borges, OLIVEIRA, Trícia Maria Ferreira da Silva, SOARES, Rodrigo Martins“…In visceral leishmaniasis, the detection of the agent is of paramount importance to identify reservoirs of infection. …”
Publicado 2016
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5157por Rafizadeh, Sayena, Saraei, Mehrzad, Abaei, Mohammad Reza, Oshaghi, Mohammad Ali, Mohebali, Mehdi, Peymani, Amir, Naserpour-Farivar, Taghi, Bakhshi, Hassan, Rassi, Yavar“…BACKGROUND: Leishmaniasis is an important public health disease in many developing countries as well in Iran. …”
Publicado 2016
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5158por Fernandes, Maria Cecilia, Dillon, Laura A. L., Belew, Ashton Trey, Bravo, Hector Corrada, Mosser, David M., El-Sayed, Najib M.“…While lethal to many microbes, they are the primary host cells of Leishmania spp. parasites, the obligate intracellular pathogens that cause leishmaniasis. We conducted transcriptomic profiling of two Leishmania species and the human macrophage over the course of intracellular infection by using high-throughput RNA sequencing to characterize the global gene expression changes and reprogramming events that underlie the interactions between the pathogen and its host. …”
Publicado 2016
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5159por Cannet, Arnaud, Akhoundi, Mohammad, Michel, Gregory, Marty, Pierre, Delaunay, Pascal“…Leishmaniasis is a vector-borne disease that is transmitted by sandflies and caused by obligate intracellular protozoa of the genus Leishmania. …”
Publicado 2016
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5160“…RESULTS: After 20 continuous passages, the BALB/c mice tested negative in the development of leishmaniasis. At a concentration of 0.1 µg/mL, L. tropica showed resistance to amp B. …”
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