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5361por Casanova, Claudio, Colla-Jacques, Fernanda E., Hamilton, James G. C., Brazil, Reginaldo P., Shaw, Jeffrey J.“…BACKGROUND: American visceral leishmaniasis (AVL) is an emerging disease in the state of São Paulo, Brazil. …”
Publicado 2015
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5362por da Silva, Thais Almeida Marques, Gomes, Luciana Inácia, Oliveira, Edward, Coura-Vital, Wendel, Silva, Letícia de Azevedo, Pais, Fabiano Sviatopolk-Mirsky, Ker, Henrique Gama, Reis, Alexandre Barbosa, Rabello, Ana, Carneiro, Mariangela“…BACKGROUND: Certain municipalities in the Belo Horizonte Metropolitan Area (BHMA), Minas Gerais, Brazil, have the highest human visceral leishmaniasis (VL) mortality rates in the country and also demonstrate high canine seropositivity. …”
Publicado 2015
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5363por Timm, Jennifer, Bosch-Navarrete, Cristina, Recio, Eliseo, Nettleship, Joanne E., Rada, Heather, González-Pacanowska, Dolores, Wilson, Keith S.“…Leishmania spp. is a protozoan parasite and the causative agent of leishmaniasis. Thymidine kinase (TK) catalyses the transfer of the γ-phosphate of ATP to 2’-deoxythymidine (dThd) forming thymidine monophosphate (dTMP). …”
Publicado 2015
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5364“…BACKGROUND: Despite its largely mountainous terrain for which this Himalayan country is a popular tourist destination, Nepal is now endemic for five major vector-borne diseases (VBDs), namely malaria, lymphatic filariasis, Japanese encephalitis, visceral leishmaniasis and dengue fever. There is increasing evidence about the impacts of climate change on VBDs especially in tropical highlands and temperate regions. …”
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5365por de Paiva-Cavalcanti, Milena, de Morais, Rayana Carla Silva, Pessoa-e-Silva, Rômulo, Trajano-Silva, Lays Adrianne Mendonça, Gonçalves-de-Albuquerque, Suênia da Cunha, Tavares, Diego de Hollanda Cavalcanti, Brelaz-de-Castro, Maria Carolina Accioly, Silva, Rafael de Freitas e, Pereira, Valéria Rêgo Alves“…They cause a spectrum of diseases, most notably visceral (VL), cutaneous (CL), and mucosal (ML) leishmaniasis, which affect millions of people around the world, each year. …”
Publicado 2015
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5366por Davami, Mohammad Hassan, Motazedian, Mohammad Hossein, Kalantari, Mohsen, Asgari, Qasem, Mohammadpour, Iraj, Sotoodeh-Jahromi, Abdolreza, Solhjoo, Kavous, Pourahmad, Morteza“…BACKGROUND: Zoonotic Cutaneous Leishmaniasis (ZCL) is endemic in many parts of Iran. …”
Publicado 2014
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5367por Miura, Ryuichi, Kooriyama, Takanori, Yoneda, Misako, Takenaka, Akiko, Doki, Miho, Goto, Yasuyuki, Sanjoba, Chizu, Endo, Yasuyuki, Fujiyuki, Tomoko, Sugai, Akihiro, Tsukiyama-Kohara, Kyoko, Matsumoto, Yoshitsugu, Sato, Hiroki, Kai, Chieko“…To evaluate the protective effects of the recombinant CDVs against cutaneous leishmaniasis in dogs, dogs were immunized with one recombinant CDV or a cocktail of three recombinant CDVs, before intradermal challenge (in the ears) with infective-stage promastigotes of Leishmania major. …”
Publicado 2015
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5368“…In the present study, the CRISPR-Cas9 system has been adapted to Leishmania donovani, a protozoan parasite that causes fatal human visceral leishmaniasis. We introduced the Cas9 nuclease into L. donovani and generated guide RNA (gRNA) expression vectors by using the L. donovani rRNA promoter and the hepatitis delta virus (HDV) ribozyme. …”
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5369por Figueira, Cláudio Pereira, Carvalhal, Djalma Gomes Ferrão, Almeida, Rafaela Andrade, Hermida, Micely d’ El-Rei, Touchard, Dominique, Robert, Phillipe, Pierres, Anne, Bongrand, Pierre, dos-Santos, Washington LC“…These changes in phagocyte function may be important for parasite dissemination and distribution of lesions in leishmaniasis.…”
Publicado 2015
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5370“…Aplastic anemia was the most common cause of pancytopenia that was observed in 83 cases (33.47%) followed by megaloblastic anemia in 52 cases (20.97%), leishmaniasis in 34 patients (13.71%), hypersplenism also in 34 patients (13.71%), and tuberculosis and other connective tissue disorders in 18 cases (7.26%). …”
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5371por Sadeghi, Somayeh, Seyed, Negar, Etemadzadeh, Mohammad-Hossein, Abediankenari, Saeid, Rafati, Sima, Taheri, Tahereh“…Leishmaniasis is a worldwide uncontrolled parasitic disease due to the lack of effective drug and vaccine. …”
Publicado 2015
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5372“…Leishmania infantum, causative agent of visceral leishmaniasis in humans, illustrates a complex lifecycle pertaining to two extreme environments, namely, the gut of the sandfly vector and human macrophages. …”
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5373por Pessoa, Grasielle Caldas DÁvila, Lopes, Josiane Valadão, Rocha, Marília Fonseca, Pinheiro, Letícia C., Rosa, Aline Cristine Luiz, Michalsky, Érika Monteiro, Dias, Edelberto Santos“…BACKGROUND: Given the increase in cases of visceral leishmaniasis in recent years, associated with the socio-economic impact of this disease, as well as the wide distribution of Lutzomyia longipalpis in Brazil and the likelihood that this vector may develop resistance to insecticides used for control, the Ministry of Health considers as crucial the creation of a network in order to study and monitor the resistance of this vector to insecticides used for control. …”
Publicado 2015
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5374por Nühs, Andrea, De Rycker, Manu, Manthri, Sujatha, Comer, Eamon, Scherer, Christina A., Schreiber, Stuart L., Ioset, Jean-Robert, Gray, David W.“…Visceral leishmaniasis is an important parasitic disease of the developing world with a limited arsenal of drugs available for treatment. …”
Publicado 2015
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5375por Brilhante, Andreia Fernandes, Nunes, Vânia Lúcia Brandão, Kohatsu, Kleber Augusto, Galati, Eunice Aparecida Bianchi, Rocca, Maria Elizabeth Ghizzi, Ishikawa, Edna Aoba Yassui“…CONCLUSIONS: As Bi. flaviscutellata is only slightly attracted by humans, the transmission of L. amazonensis in the study area may have a zoonotic character; however, the sympatric occurrence of this parasite and Lu. longipalpis should be taken into consideration by the local health authorities since this sand fly has already been found with L. amazonensis DNA in a focus of canine visceral leishmaniasis in Bonito municipality.…”
Publicado 2015
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5376por Firdessa, Rebuma, Good, Liam, Amstalden, Maria Cecilia, Chindera, Kantaraja, Kamaruzzaman, Nor Fadhilah, Schultheis, Martina, Röger, Bianca, Hecht, Nina, Oelschlaeger, Tobias A., Meinel, Lorenz, Lühmann, Tessa, Moll, Heidrun“…BACKGROUND: Cutaneous leishmaniasis (CL) is a neglected tropical disease caused by protozoan parasites of the genus Leishmania. …”
Publicado 2015
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5377por de Mendonça, Sergio Coutinho Furtado, Cysne-Finkelstein, Léa, Matos, Denise Cristina de Souza“…Kinetoplastid membrane protein-11 (KMP-11), a protein present in all kinetoplastid protozoa, is considered a potential candidate for a leishmaniasis vaccine. In Leishmania amazonensis, KMP-11 is expressed in promastigotes and amastigotes. …”
Publicado 2015
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5378por de Paiva, Rita Marcia Cardoso, Grazielle-Silva, Viviane, Cardoso, Mariana Santos, Nakagaki, Brenda Naemi, Mendonça-Neto, Rondon Pessoa, Canavaci, Adriana Monte Cassiano, Souza Melo, Normanda, Martinelli, Patrícia Massara, Fernandes, Ana Paula, daRocha, Wanderson Duarte, Teixeira, Santuza M. R.“…Leishmaniasis, a human parasitic disease with manifestations ranging from cutaneous ulcerations to fatal visceral infection, is caused by several Leishmania species. …”
Publicado 2015
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5379por Chaara, Dhekra, Bañuls, Anne- Laure, Haouas, Najoua, Talignani, Loïc, Lami, Patrick, Mezhoud, Habib, Harrat, Zoubir, Dedet, Jean-Pierre, Babba, Hamouda, Pratlong, Francine“…L. tropica), which causes cutaneous leishmaniasis in Maghreb, was recently described in this region and identified as a subpopulation of L. tropica. …”
Publicado 2015
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5380por Rochael, Natalia C., Guimarães-Costa, Anderson B., Nascimento, Michelle T. C., DeSouza-Vieira, Thiago S., Oliveira, Matheus P., Garcia e Souza, Luiz F., Oliveira, Marcus F., Saraiva, Elvira M.“…A better understanding of both mechanisms of NET release, and the NETs effects on the host immune system modulation, could support the development of new potential therapeutic strategies for leishmaniasis.…”
Publicado 2015
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