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5501por Jafari, Reza, Abdoli, Hamid, Arandian, Mohammad Hossein, Shareghi, Nilofar, Ghanei, Maryam, Jalali-Zand, Nilofar, Nekoeian, Shahram, Veysi, Arshad, Montazeri, Ahmad, Ghasemi, Amirabdollah, Ramazanpour, Javad, Fadaei, Reza, Akhavan, Amir Ahmad“…BACKGROUND: Esfahan Province is considered as one of the main focus of zoonotic cutaneous leishmaniasis (ZCL) in Iran. Recently, ZCL distribution is expanding through this province leading to report of new cases in non-endemic areas. …”
Publicado 2020
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5502por Tabrez, Shams, Rahman, Fazlur, Ali, Rahat, Alouffi, Abdulaziz S., Akand, Sajjadul Kadir, Alshehri, Bader Mohammed, Alshammari, Fahdah Ayed, Alam, Aftab, Alaidarous, Mohammed A., Banawas, Saeed, Dukhyil, Abdul Aziz Bin, Rub, Abdur“…In conclusion, cynaroside may be used alone or in combination with existing drug, miltefosine to control leishmaniasis with less cytotoxicity.…”
Publicado 2021
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5503por Tabbabi, Ahmed, Watanabe, Shinya, Mizushima, Daiki, Caceres, Abraham G., Gomez, Eduardo A, Yamamoto, Daisuke S., Cui, Longzhu, Hashiguchi, Yoshihisa, Kato, Hirotomo“…Differences in the gut microbial content of Lutzomyia (Lu.) ayacuchensis, a primary vector of Andean-type cutaneous leishmaniasis in Ecuador and Peru, may influence the susceptibility of these sand flies to infection by Leishmania. …”
Publicado 2020
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5504por Bradley, Mark, Taylor, Rachel, Jacobson, Julie, Guex, Morgane, Hopkins, Adrian, Jensen, Julie, Leonard, Lynn, Waltz, Johannes, Kuykens, Luc, Sow, Papa Salif, Madeja, Ulrich-Dietmar, Hida, Takayuki, Ole-Moiyoi, Kileken, King, Jonathan, Argaw, Daniel, Mohamed, Jamsheed, Polo, Maria Rebollo, Yajima, Aya, Ottesen, Eric“…Extraordinary global health advances have been made in filariasis, onchocerciasis, trachoma, trypanosomiasis, leishmaniasis, schistosomiasis, intestinal parasites and others; and these advances are taking place in the context of strengthening health systems and meeting the global development goals espoused by the WHO. …”
Publicado 2021
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5505por Schwabl, Philipp, Boité, Mariana C., Bussotti, Giovanni, Jacobs, Arne, Andersson, Bjorn, Moreira, Otacilio, Freitas-Mesquita, Anita L., Meyer-Fernandes, Jose Roberto, Telleria, Erich L., Traub-Csekö, Yara, Vaselek, Slavica, Leštinová, Tereza, Volf, Petr, Morgado, Fernanda N., Porrozzi, Renato, Llewellyn, Martin, Späth, Gerald F., Cupolillo, Elisa“…Leishmania infantum causes visceral leishmaniasis, a deadly vector-borne disease introduced to the Americas during the colonial era. …”
Publicado 2021
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5506por Comai, Giorgia, Mistral De Pascali, Alessandra, Busutti, Marco, Morini, Silvia, Ortalli, Margherita, Conte, Diletta, Re, Maria Carla, La Manna, Gaetano, Varani, Stefania“…Despite being considered a tropical disease, visceral leishmaniasis (VL) caused by L. infantum is also endemic in the Mediterranean Europe and represents an increasing cause of morbidity and mortality in solid organ transplant (SOT) recipients. …”
Publicado 2020
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5507por Bijlmakers, Marie-José“…The numbers of drugs available to treat these diseases, Human African Trypanosomiasis, Chagas' disease and Leishmaniasis are very limited and existing treatments have substantial shortcomings in delivery method, efficacy and safety. …”
Publicado 2021
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5508por Garlapati, Rajesh, Iniguez, Eva, Serafim, Tiago D., Mishra, Prabhas K., Rooj, Basab, Sinha, Bikas, Valenzuela, Jesus G., Srikantiah, Sridhar, Bern, Caryn, Kamhawi, Shaden“…Visceral leishmaniasis (VL) is a potentially deadly parasitic disease. …”
Publicado 2021
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5509por Sampaio, Julia Ramos, Soares, Rodrigo Pedro, Barral, Thiago Doria, Passos, Gabriela Porfirio, Fonseca, Maisa Santos, Meyer, Roberto, Barrouin-Melo, Stella Maria, Portela, Ricardo Wagner“…Since GIPLs can be extracted from the same parasite pellet as LPGs, this work aimed to evaluate the immune recognition of GIPLs by Leishmania infantum-infected dogs and its use for canine leishmaniasis (CanL) immunodiagnosis. Like LPG, GIPLs were recognized by sera from L. infantum-infected dogs, but with less sensitivity (83.8%). …”
Publicado 2021
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5510“…To update the geographical distribution of Leishmania spp. causing cutaneous affection, we examined a set of Giemsa-stained smears prepared from skin lesions of the patients suspected to have cutaneous leishmaniasis (CL) in various geographical areas in Algeria. …”
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5511“…In addition, the average annual growth percentage was calculated for each disease. (3) Results: In the last decade, the NTDs with the highest number of publications in the world were dengue and leishmaniasis. The United States was the most prolific country in the world in 15 out of 19 NTDs analyzed. …”
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5512por de Souza, João H, Michelon, Alexandra, Banhuk, Fernanda W, Staffen, Izabela V, Klein, Elissandro J, da Silva, Edson A, Menolli, Rafael A“…Conclusions: This is the first study demonstrating the activity of an amyrin rich-extract against microorganisms that cause Chagas disease and leishmaniasis, as well as its antioxidant capacity, justifying further studies for future in-vivo tests.…”
Publicado 2020
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5513por Sellau, Julie, Puengel, Tobias, Hoenow, Stefan, Groneberg, Marie, Tacke, Frank, Lotter, Hannelore“…This includes not only hepatotropic viruses (e.g., hepatitis B, hepatitis C) but also bacterial and parasitic infections such as amebiasis, leishmaniasis, schistosomiasis, or echinococcosis. Recent studies of the immune mechanisms underlying liver disease show that monocytes play an essential role in determining patient outcomes. …”
Publicado 2021
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5514por Inacio, Job D. F., Fonseca, Myslene S., Limaverde-Sousa, Gabriel, Tomas, Ana M., Castro, Helena, Almeida-Amaral, Elmo E.“…Leishmania infantum is a protozoan parasite that causes a vector borne infectious disease in humans known as visceral leishmaniasis (VL). This pathology, also caused by L. donovani, presently impacts the health of 500,000 people worldwide, and is treated with outdated anti-parasitic drugs that suffer from poor treatment regimens, severe side effects, high cost and/or emergence of resistant parasites. …”
Publicado 2021
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5515por Freitas-Mesquita, Anita Leocadio, Dos-Santos, André Luiz Araújo, Meyer-Fernandes, José Roberto“…Inside vertebrate host macrophages, the parasites can differentiate into the amastigote form and multiply, causing leishmaniasis, one of the most significant neglected tropical diseases. …”
Publicado 2021
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5516por Imran, Muhammad, Jan, Hasnain, Faisal, Shah, Ali Shah, Sajjad, Shah, Sumaira, Naeem Khan, Muhammad, Taj Akbar, Muhammad, Rizwan, Muhammad, Jan, Faheem, Syed, Suliman“…All extracts were exploited for broad range of biomedical applications including leishmaniasis, in vitro anti-Alzheimer, insecticidal and cytotoxic studies. …”
Publicado 2021
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5517por Chaurasiya, Narayan D., Liu, Haining, Doerksen, Robert J., Nanayakkara, N. P. Dhammika, Walker, Larry A., Tekwani, Babu L.“…NPC1161B, the (R)-(−) enantiomer with outstanding potential for malaria radical cure, treatment of visceral leishmaniasis and pneumocystis pneumonia infections is poised for clinical development. …”
Publicado 2021
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5518por Maksouri, Hasnaa, Darif, Dounia, Estaquier, Jerome, Riyad, Myriam, Desterke, Christophe, Lemrani, Meryem, Dang, Pham My-Chan, Akarid, Khadija“…In Morocco, Leishmania major and L. tropica are the main species responsible for cutaneous leishmaniasis (CL). The impact of these parasites on human PMN functions is still unclear. …”
Publicado 2021
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5519por Vivero, Rafael José, Castañeda-Monsalve, Victor Alfonso, Romero, Luis Roberto, D. Hurst, Gregory, Cadavid-Restrepo, Gloria, Moreno-Herrera, Claudia Ximena“…Pintomyia evansi is recognized by its vectorial competence in the transmission of parasites that cause fatal visceral leishmaniasis in rural and urban environments of the Caribbean coast of Colombia. …”
Publicado 2021
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5520por Ochoa, Rodrigo, Ortega-Pajares, Amaya, Castello, Florencia A., Serral, Federico, Fernández Do Porto, Darío, Villa-Pulgarin, Janny A., Varela-M, Rubén E., Muskus, Carlos“…Leishmaniasis is a public health disease that requires the development of more effective treatments and the identification of novel molecular targets. …”
Publicado 2021
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