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6041por Ramos, Fernanda Fonseca, Costa, Lourena Emanuele, Dias, Daniel Silva, Santos, Thaís Teodoro Oliveira, Rodrigues, Marcella Rezende, Lage, Daniela Pagliara, Salles, Beatriz Cristina Silveira, Martins, Vívian Tamietti, Ribeiro, Patrícia Aparecida Fernandes, Chávez-Fumagalli, Miguel Angel, Dias, Ana Carolina Silva, Alves, Patrícia Terra, Vieira, Érica Leandro Marciano, Roatt, Bruno Mendes, Menezes-Souza, Daniel, Duarte, Mariana Costa, Teixeira, Antonio Lúcio, Goulart, Luiz Ricardo, Coelho, Eduardo Antonio Ferraz“…BACKGROUND: The development of a vaccine for the prevention of visceral leishmaniasis (VL) still represents a significant unmet medical need. …”
Publicado 2017
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6042por González, Mikel A., Bandi, Krishna K., Bell, Melissa J., Brazil, Reginaldo P., Dilger, Erin, Guerrero, Angel, Courtenay, Orin, Hamilton, James G. C.“…BACKGROUND: Lutzomyia longipalpis is the South American vector of Leishmania infantum, the etiologic agent of visceral leishmaniasis (VL). Male L. longipalpis produce a sex-aggregation pheromone that is critical in mating, yet very little is known about its accumulation over time or factors involved in release. …”
Publicado 2017
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6043por Sangare, Moussa Brema, Coulibaly, Yaya Ibrahim, Coulibaly, Siaka Yamoussa, Coulibaly, Michel Emmanuel, Traore, Bourama, Dicko, Ilo, Sissoko, Ibrahim Moussa, Samake, Sibiry, Traore, Sekou Fantamady, Nutman, Thomas Bruce, Valenzuela, Jesus Gilberto, Faye, Ousmane, Kamhawi, Shaden, Oliveira, Fabiano, Semnani, Roshanak Tolouei, Doumbia, Seydou“…BACKGROUND: Filariasis and leishmaniasis are two neglected tropical diseases in Mali. …”
Publicado 2018
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6044por Poché, David M., Garlapati, Rajesh B., Mukherjee, Shanta, Torres-Poché, Zaria, Hasker, Epco, Rahman, Tahfizur, Bharti, Aakanksha, Tripathi, Vishnu P., Prakash, Suman, Chaubey, Rahul, Poché, Richard M.“…BACKGROUND: Visceral leishmaniasis (VL) is a deadly vector-borne disease. …”
Publicado 2018
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6045“…BACKGROUND: Visceral leishmaniasis (VL) is a neglected tropical disease (NTD), caused by the intracellular protozoan parasites Leishmania donovani and Leishmania infantum. …”
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6046por Verma, Sudha, Mandal, Abhishek, Ansari, Md. Yousuf, Kumar, Ajay, Abhishek, Kumar, Ghosh, Ayan Kumar, Kumar, Ashish, Kumar, Vinod, Das, Sushmita, Das, Pradeep“…Leishmania donovani, the causative agent of Indian visceral leishmaniasis has to face several barriers of the immune system inside the mammalian host for its survival. …”
Publicado 2018
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6047por Guedes, Carlos Eduardo Sampaio, Dias, Beatriz Rocha Simões, Petersen, Antonio Luis de Oliveira Almeida, Cruz, Kercia Pinheiro, Almeida, Niara de Jesus, Andrade, Daniela Rodrigues, de Menezes, Juliana Perrone Bezerra, Borges, Valéria de Matos, Veras, Patricia Sampaio Tavares“…BACKGROUND: Leishmaniasis, one of the most neglected diseases, is a serious public health problem in many countries, including Brazil. …”
Publicado 2018
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6048por Kauffmann, Florence, Meert, Elyn, de Jonge, Kaat, Elkrim, Yvon, Hanot Mambres, Delphine, Denis, Olivier, Muraille, Eric, Magez, Stefan, De Trez, Carl“…Leishmania major (L. major) parasites are intracellular parasites belong to the Trypanosomatidae family and are the causative agent of cutaneous leishmaniasis. This disease affects approximately 1.5 million per year worldwide and there is currently no prophylactic vaccine available. …”
Publicado 2018
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6049por Almeida, Ana Paula M. M., Machado, Leopoldo F. M., Doro, Daniel, Nascimento, Frederico C., Damasceno, Leonardo, Gazzinelli, Ricardo Tostes, Fernandes, Ana Paula, Junqueira, Caroline“…Visceral leishmaniasis (VL) is a major public health issue reported as the second illness in mortality among all tropical diseases. …”
Publicado 2018
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6050por Martin-Martin, Ines, Chagas, Andrezza Campos, Guimaraes-Costa, Anderson B., Amo, Laura, Oliveira, Fabiano, Moore, Ian N., DeSouza-Vieira, Thiago S., Sanchez, Elda E., Suntravat, Montamas, Valenzuela, Jesus G., Ribeiro, Jose M. C., Calvo, Eric“…A vaccination experiment demonstrated that LuloHya and Lundep confer protective immunity against cutaneous leishmaniasis using the Lu. longipalpis—Leishmania major combination as a model. …”
Publicado 2018
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6051por Yu, Aiping, Wang, Ying, Yin, Jianhai, Zhang, Jing, Cao, Shengkui, Cao, Jianping, Shen, Yujuan“…The results indicated that mRNAs co-expressed with the lncRNAs are mainly involved in regulating the actin cytoskeleton, Salmonella infection, leishmaniasis, and the vascular endothelial growth factor (VEGF) signaling pathway. …”
Publicado 2018
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6052por Ontoria, Eduardo, Hernández-Santana, Yasmina E., González-García, Ana C., López, Manuel C., Valladares, Basilio, Carmelo, Emma“…The overexpression of these Th1/M1 markers is restored later in the chronic phase (8 wpi), suggesting the generation of a classical “protective response” against leishmaniasis. Nonetheless, the parasitic burden rockets at this timepoint. …”
Publicado 2018
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6053por Pech-May, Angélica, Ramsey, Janine M., González Ittig, Raúl E., Giuliani, Magali, Berrozpe, Pablo, Quintana, María G., Salomón, Oscar D.“…In the Americas, this sandfly is the main vector of Leishmania infantum, the parasite responsible for Visceral Leishmaniasis (VL). The Lu. longipalpis complex consists of at least four sibling species, however, there is no current consensus on the number of haplogroups, or on their divergence. …”
Publicado 2018
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6054por López-Muñoz, Rodrigo A., Molina-Berríos, Alfredo, Campos-Estrada, Carolina, Abarca-Sanhueza, Patricio, Urrutia-Llancaqueo, Luis, Peña-Espinoza, Miguel, Maya, Juan D.“…However, these mediators seem to have different roles in visceral or cutaneous leishmaniasis. Finally, although T. brucei infections are less well studied in terms of their relationship with inflammation, it has been found that arachidonic acid-derived lipids act as key regulators of the host immune response and parasite burden. …”
Publicado 2018
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6055“…BACKGROUND: Leishmaniosis/leishmaniasis consists of a wide group of diseases, caused by different Leishmania species and having different hosts. …”
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6056por Bifeld, Eugenia, Lorenzen, Stephan, Bartsch, Katharina, Vasquez, Juan-José, Siegel, T. Nicolai, Clos, Joachim“…In the protozoan parasite Leishmania donovani, causative agent of the fatal visceral leishmaniasis, HSP90 activity is essential for cell proliferation and survival. …”
Publicado 2018
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6057por Ferreira, Tainá Neves, Pita-Pereira, Daniela, Costa, Samara Graciane, Brazil, Reginaldo Peçanha, Moraes, Caroline Silva, Díaz-Albiter, Hector Manuel, Genta, Fernando Ariel“…BACKGROUND: The sand fly Lutzomyia longipalpis is the main vector of American visceral leishmaniasis, a disease caused by parasites of the genus Leishmania. …”
Publicado 2018
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6058por Chapman, Lloyd A. C., Morgan, Alex L. K., Adams, Emily R., Bern, Caryn, Medley, Graham F., Hollingsworth, T. Déirdre“…BACKGROUND: Age patterns in asymptomatic and symptomatic infection with Leishmania donovani, the causative agent of visceral leishmaniasis (VL) in the Indian subcontinent (ISC), are currently poorly understood. …”
Publicado 2018
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6059por Mohammadpour, Iraj, Hatam, Gholam Reza, Handjani, Farhad, Bozorg-Ghalati, Farzaneh, PourKamal, Daniel, Motazedian, Mohammad Hossein“…BACKGROUND: Cutaneous leishmaniasis (CL) caused by Leishmania species, is a geographically extensive disease that infects humans and animals. …”
Publicado 2019
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6060por Castro Neto, Artur L., Brito, Adriana N. A. L. M., Rezende, Antonio M., Magalhães, Franklin B., de Melo Neto, Osvaldo P.“…BACKGROUND: The leishmaniasis are parasitic diseases caused by protozoans of the genus Leishmania, highly divergent eukaryotes, characterized by unique biological features. …”
Publicado 2019
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