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6141por Balzan, Martin“…The geographical distribution of Phlebotomus sand-flies and the relative distribution of arthropod borne diseases Leishmaniasis and Phlebovirus infections especially the Sicilian Sandfly fever group corresponds to most areas of low prevalence of SARS-CoV-2. …”
Publicado 2020
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6142por Sharma, Rohit, Viana, Sayonara M., Ng, Dennis K. P., Kolli, Bala K., Chang, Kwang Poo, de Oliveira, Camila I.“…Installation of dual photodynamic mechanisms ensures complete inactivation of species in the Leishmania subgenus, raising the prospect of their safe and effective application as whole-cell vaccines against leishmaniasis. Here, we report the successful extension of this approach to L. braziliensis in the Viannia subgenus, viz. genetic engineering of promastigotes for cytosolic accumulation of UV-sensitive uroporphyrin (URO) and their loading with red light excitable phthalocyanines (PC) that was cationized by chemical engineering. …”
Publicado 2020
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6143por Queiroga, Tamyres Bernadete Dantas, Ferreira, Henrique Rafael Pontes, dos Santos, Wilo Victor, de Assis, Ana Beatriz Lourenço, de Araújo Neto, Vicente Toscano, da Câmara, Antônia Cláudia Jácome, Fagundes Neto, João Ciro, dos Reis, Romeika Karla, Nascimento, Manuela Sales Lima, Gama, Renata Antonaci, Guedes, Paulo Marcos Matta“…BACKGROUND: Leishmania infantum is the etiological agent of visceral leishmaniasis (VL) in the New World, where the sand fly Lutzomyia longipalpis and domestic dogs are considered the main vector and host reservoirs, respectively. …”
Publicado 2020
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6144por Rahimi, Sara, khamesipour, Ali, Akhavan, Amir Ahmad, Rafinejad, Javad, Ahmadkhaniha, Reza, Bakhtiyari, Mahmood, Veysi, Arshad, Akbarzadeh, Kamran“…BACKGROUND: Leishmaniasis is a major parasitic disease worldwide, except in Australia and Antarctica, and it poses a significant public health problem. …”
Publicado 2021
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6145por Cloots, Kristien, Singh, Om Prakash, Singh, Abhishek Kumar, Van der Auwera, Gert, Kumar, Prashant, Gedda, Mallikarjuna Rao, Rai, Tulika Kumari, Hasker, Epco, Sundar, Shyam, Boelaert, Marleen“…BACKGROUND: In the endgame of the elimination initiative of visceral leishmaniasis (VL) on the Indian subcontinent, one of the main questions remaining is whether asymptomatically infected individuals also contribute to transmission. …”
Publicado 2021
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6146por Kalesh, Karunakaran, Sundriyal, Sandeep, Perera, Hirunika, Cobb, Steven L., Denny, Paul W.“…IMPORTANCE Leishmania spp. are the causative agents of leishmaniasis, a poverty-related disease, which is endemic in >90 countries worldwide, affecting approximately 12 million people, with an estimated 700,000 to 1 million new cases and around 70,000 deaths annually. …”
Publicado 2021
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6147por Guimarães, T. T., Gomes, S. M. R., Albuquerque, R. A. A. C., Lima, A. K. C., Braga, G. F., Souza, J. B., Assis, M., Brito, A. C. S., Santos, R. F., Da Silva, T., Siqueira, L. M., Ventura, B. D., Rodrigues, L. S., Terra, R., Da Silva, S. A. G., Dutra, P. M. L.“…Several studies suggest that moderate amounts of exercise lead to a Th1 response, favoring the resolution of infections caused by intracellular microorganisms, while high volumes of exercise tend to direct the response to Th2, favoring infection by them. Leishmaniasis is a parasitic disease promoted by parasites of the Leishmania genus, with clinical manifestations that vary according to the species of the parasite and the immune response of the host. …”
Publicado 2021
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6148por Stucke, Emily M., Dara, Antoine, Dwivedi, Ankit, Hodges, Theresa K., Ott, Sandra, Coulibaly, Drissa, Koné, Abdoulaye K., Traoré, Karim, Guindo, Bouréima, Tangara, Bourama M., Niangaly, Amadou, Daou, Modibo, Diarra, Issa, Tolo, Youssouf, Sissoko, Mody, Tallon, Luke J., Sadzewicz, Lisa, Zhou, Albert E., Laurens, Matthew B., Ouattara, Amed, Kouriba, Bourema, Doumbo, Ogobara K., Takala-Harrison, Shannon, Serre, David, Plowe, Christopher V., Thera, Mahamadou A., Travassos, Mark A., Silva, Joana C.“…While our results are focused on the malaria parasite Plasmodium falciparum, this approach has broad applicability to other highly diverse antigens from other parasites and pathogens such as those that cause giardiasis and leishmaniasis.…”
Publicado 2021
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6149“…This review revealed several cases of histoplasmosis misdiagnosed as other conditions including tuberculosis (n = 3, 6.8%), pneumonia (n = 1, 2.3%), cancers (n = 4, 9.1%), nephritic syndrome (n = 1, 2.3%), leishmaniasis (n = 1, 2.3%), and hyperreactive malarial splenomegaly syndrome (n = 1, 2.3%). …”
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6150por Oliveira, Leandro G., Souza-Testasicca, Míriam C., Ricotta, Tiago Nery Queiroga, Vago, Juliana P., dos Santos, Liliane M., Crepaldi, Frederico, Lima, Kátia M., Queiroz-Junior, Celso, Sousa, Lirlândia P., Fernandes, Ana Paula“…Since activation of inflammatory responses is a crucial aspect for the control of infectious processes, these findings may be important for the search of new and specific strategies of vaccines and treatment for tegumentary leishmaniasis.…”
Publicado 2022
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6151por Dermicik, Filiz, Lopez Kostka, Susanna, Tenzer, Stefan, Waisman, Ari, Von Stebut, Esther“…ABSTRACT: In cutaneous leishmaniasis, infection of dendritic cells (DC) is essential for generation of T cell-dependent protective immunity. …”
Publicado 2021
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6152por Quintela-Carvalho, Graziele, Goicochea, Astrid Madeleine Calero, Mançur-Santos, Vanessa, Viana, Sayonara de Melo, Luz, Yasmin da Silva, Dias, Beatriz Rocha Simões, Lázaro-Souza, Milena, Suarez, Martha, de Oliveira, Camila Indiani, Saraiva, Elvira M., Brodskyn, Cláudia I., Veras, Patrícia T., de Menezes, Juliana P.B., Andrade, Bruno B., Lima, Jonilson Berlink, Descoteaux, Albert, Borges, Valéria M.“…Visceral leishmaniasis (VL) is often associated with hematologic manifestations that may interfere with neutrophil response. …”
Publicado 2022
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6153“…BACKGROUND: Leishmaniasis is a neglected infectious disease caused by protozoa of the genus Leishmania. …”
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6154por Alcolea, Pedro J., Alonso, Ana, García-Tabares, Francisco, Larraga, Jaime, Martins, Luis T. C., Loayza, Franciso J., Ruiz-García, Silvia, Larraga, Vicente“…Leishmania donovani causes anthroponotic visceral leishmaniasis, responsible for about 50,000 annual deaths worldwide. …”
Publicado 2022
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6155por Vital, Tamires, Teixeira, Ana Izabel Passarella, Silva, Débora Marcolino, de Carvalho, Bruna Caroline, Dallago, Bruno, Hagström, Luciana, Hecht, Mariana Machado, Nitz, Nadjar, Abad-Franch, Fernando“…BACKGROUND: Domestic dogs are primary reservoir hosts of Leishmania infantum, the agent of visceral leishmaniasis. Detecting dog infections is central to epidemiological inference, disease prevention, and veterinary practice. …”
Publicado 2022
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6156por Schäfer, Ingo, Schmidt, Albert, Gräßer, Fritz, Schieszler, Andrea, Aupperle-Lellbach, Heike, Loesenbeck, Gerhard, Gentil, Michaela, Müller, Elisabeth, Naucke, Torsten J.“…This case report supports the hypothesis that immunosuppression increases the risk of clinical signs of leishmaniasis in cats. Alpha2- and gamma-globulin peaks in serum protein capillary electrophoresis are supportive criteria for the diagnosis of L. infantum infection. …”
Publicado 2023
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6157por Epelboin, Loïc, Abboud, Philippe, Abdelmoumen, Karim, About, Frédégonde, Adenis, Antoine, Blaise, Théo, Blaizot, Romain, Bonifay, Timothée, Bourne-Watrin, Morgane, Boutrou, Mathilde, Carles, Gabriel, Carlier, Pierre-Yves, Carod, Jean-François, Carvalho, Luisiane, Couppié, Pierre, De Toffol, Bertrand, Delon, François, Demar, Magalie, Destoop, Justin, Douine, Maylis, Droz, Jean-Pierre, Elenga, Narcisse, Enfissi, Antoine, Franck, Yves-Kénol, Fremery, Alexis, Gaillet, Mélanie, Kallel, Hatem, Kpangon, Arsène Amadouhé, Lavergne, Anne, Le Turnier, Paul, Maisonobe, Lucas, Michaud, Céline, Mutricy, Rémi, Nacher, Mathieu, Naldjinan-Kodbaye, Richard, Oberlis, Margot, Odonne, Guillaume, Osei, Lindsay, Pujo, Jean, Rabier, Sébastien, Roman-Laverdure, Brigitte, Rousseau, Cyril, Rousset, Dominique, Sabbah, Nadia, Sainte-Rose, Vincent, Schaub, Roxane, Sylla, Karamba, Tareau, Marc-Alexandre, Tertre, Victor, Thorey, Camille, Vialette, Véronique, Walter, Gaëlle, Zappa, Magaly, Djossou, Félix, Vignier, Nicolas“…In addition to these pathologies, many tropical diseases are present in an endemic and / or epidemic mode such as malaria, leishmaniasis, Chagas disease, histoplasmosis or dengue. …”
Publicado 2023
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6158Publicado 1995“…In experimental murine cutaneous leishmaniasis caused by Leishmania major (Lm), the cellular determinants governing development of protective or exacerbative T cells are not well understood. …”
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6159Comparative genomic analysis of Leishmania (Viannia) peruviana and Leishmania (Viannia) braziliensispor Valdivia, Hugo O., Reis-Cunha, João L., Rodrigues-Luiz, Gabriela F., Baptista, Rodrigo P., Baldeviano, G. Christian, Gerbasi, Robert V., Dobson, Deborah E., Pratlong, Francine, Bastien, Patrick, Lescano, Andrés G., Beverley, Stephen M., Bartholomeu, Daniella C.“…BACKGROUND: The Leishmania (Viannia) braziliensis complex is responsible for most cases of New World tegumentary leishmaniasis. This complex includes two closely related species but with different geographic distribution and disease phenotypes, L. …”
Publicado 2015
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6160por Singh, Ruby, Purkait, Bidyut, Abhishek, Kumar, Saini, Savita, Das, Sushmita, Verma, Sudha, Mandal, Abhishek, Ghosh, Ayan Kr., Ansari, Yousuf, Kumar, Ashish, Sardar, Abul H., Kumar, Ajay, Parrack, Pradeep, Das, Pradeep“…So, LdUMSBP may be an attractive target for rational drug designing and LdU(−/+) parasites could be considered as a live attenuated vaccine candidate against visceral leishmaniasis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13578-016-0072-z) contains supplementary material, which is available to authorized users.…”
Publicado 2016
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