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6201por Lin, Tianye, Chen, Weijian, Yang, Peng, Li, Ziqi, Wei, Qiushi, Liang, Du, Wang, Haibin, He, Wei, Zhang, Qingwen“…Then, GO and KEGG pathway enrichment analysis revealed that upregulated DEGs focused on the signaling pathways related to staphylococcus aureus infection, leishmaniasis, antigen processing, and presentation, as well as asthma and graft-versus-host disease. …”
Publicado 2021
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6202por Pereira, Luiza O. R., Sousa, Cíntia S., Ramos, Hellen C. P., Torres-Santos, Eduardo C., Pinheiro, Liliane S., Alves, Marcelo R., Cuervo, Patricia, Romero, Gustavo A. Sierra, Boité, Mariana C., Porrozzi, Renato, Cupolillo, Elisa“…BACKGROUND: Pentavalent antimonial-based chemotherapy is the first-line approach for leishmaniasis treatment and disease control. Nevertheless antimony-resistant parasites have been reported in some endemic regions. …”
Publicado 2021
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6203por Kalesh, Karunakaran, Wei, Wenbin, Mantilla, Brian S., Roumeliotis, Theodoros I., Choudhary, Jyoti, Denny, Paul W.“…IMPORTANCE Advances in proteomics and mass spectrometry have revealed the mRNA-binding proteins in many eukaryotic organisms, including the protozoan parasites Leishmania spp., the causative agents of leishmaniasis, a major infectious disease in over 90 tropical and subtropical countries. …”
Publicado 2022
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6204por Hosseini Farash, Bibi Razieh, Mohebali, Mehdi, Kazemi, Bahram, Fata, Abdolmajid, Hajjaran, Homa, Akhoundi, Behnaz, Raoofian, Reza, Mastroeni, Pietro, Moghaddas, Elham, Khaledi, Azad, Salehi Sangani, Ghodratollah“…Mediterranean type of visceral leishmaniasis (VL) is a zoonotic parasitic infection. …”
Publicado 2022
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6205“…BACKGROUND: Sand flies vector several human pathogens, including Leishmania species, which cause leishmaniases. A leishmaniasis vaccine does not yet exist, so the most common prevention strategies involve personal protection and insecticide spraying. …”
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6206por González, Mikel A., Bell, Melissa J., Bernhardt, Scott A., Brazil, Reginaldo P., Dilger, Erin, Courtenay, Orin, Hamilton, James G. C.“…BACKGROUND: In Brazil, members of the sand fly species complex Lutzomyia longipalpis transmit Leishmania infantum, a protist parasite that causes visceral leishmaniasis. Male Lu. longipalpis produce a sex pheromone that is attractive to both females and males. …”
Publicado 2019
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6207por Leão, Paula de Oliveira, Pereira Júnior, Antonio Marques, de Paulo, Paula Frassinetti Medeiros, Carvalho, Luis Paulo Costa, Souza, Ana Beatriz Nascimento, da Silva, Michelli Santos, Castro, Thaís Santos, Freitas, Moisés Thiago de Souza, Rodrigues, Moreno Magalhães de Souza, Ferreira, Gabriel Eduardo Melim, Medeiros, Jansen Fernandes“…BACKGROUND: Almost 1000 cases of American cutaneous leishmaniasis have been registered yearly in Rondônia State, Brazil. …”
Publicado 2020
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6208Bio-guided isolation of anti-leishmanial natural products from Diospyros gracilescens L. (Ebenaceae)por Njanpa, Cyrille Armel N., Wouamba, Steven Collins N., Yamthe, Lauve Rachel T., Dize, Darline, Tchatat, Brice Mariscal T., Tsouh, Patrick Valère F., Pouofo, Michel Nguiam, Jouda, Jean Bosco, Ndjakou, Bruno Lenta, Sewald, Norbert, Kouam, Simeon Fogue, Boyom, Fabrice Fekam“…However, further structure-activity-relationship studies of 1-deoxyinositol could lead to more potent and selective hit derivatives of interest for detailed drug discovery program against visceral leishmaniasis. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12906-021-03279-1.…”
Publicado 2021
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6209“…Although the population is aware of dengue fever and the role of mosquitoes in transmitting it, information campaigns are required for other historically neglected VBDs, such as leishmaniasis, Chagas disease, and, even, rickettsiosis. …”
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6210por Álvarez, Luis, Marín-García, Pablo-Jesús, Rentero-Garrido, Pilar, Martinez-Jimenez, Celia Pilar, Llobat, Lola“…BACKGROUND: The Ibizan Hound is a canine breed native to the Mediterranean region, where leishmaniasis is an endemic zoonosis. Several studies indicate a low prevalence of this disease in Ibizan Hound dogs, whereas other canine breeds present a high prevalence. …”
Publicado 2023
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6211por Gizzarelli, Manuela, Foglia Manzillo, Valentina, Inglese, Antonio, Montagnaro, Serena, Oliva, Gaetano“…The following events were considered: decreased and negative ELISA results; improvement/recovery of the clinical and clinicopathological alterations; and relapse of leishmaniasis. One hundred seventy-three dogs (75f and 98m) were retrospectively included in the study by examining their clinical records since the first diagnosis of CanL. …”
Publicado 2023
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6212por Bai, Jiachen, Zhou, Guizhen, Hao, Shaopeng, Liu, Yucheng, Guo, Yanhua, Wang, Jingjing, Liu, Hongtao, Wang, Longfei, Li, Jun, Liu, Aiju, Sun, Wendell Q., Wan, Pengcheng, Fu, Xiangwei“…The results suggested that various differentially expressed genes and proteins (DEGs and DEPs) were mainly enriched in leishmaniasis and hematopoietic cell lineage, and Fc gamma receptor Ia (FCGR1A) was significantly downregulated in cryopreserved sperm both at mRNA and protein levels in comparison with the fresh counterpart. …”
Publicado 2023
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6213por Ribeiro-Romão, Raquel Peralva, Saavedra, Andrea Franco, Da-Cruz, Alda Maria, Pinto, Eduardo Fonseca, Moreira, Otacilio C.“…BACKGROUND: Cutaneous leishmaniasis (CL) is a neglected disease with a broad spectrum of clinical manifestations, ranging from small cutaneous nodules to severe mucosal tissue destruction. …”
Publicado 2016
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6214por Chowdhury, Rajib, Chowdhury, Vashkar, Faria, Shyla, Islam, Saiful, Maheswary, Narayan Prosad, Akhter, Shireen, Islam, Md. Sahidul, Dash, Aditya Prasad, Kroeger, Axel, Banu, Qamar“…BACKGROUND: Visceral leishmaniasis (VL) in the Indian subcontinent is a fatal disease if left untreated. …”
Publicado 2018
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6215“…Investigations from infectious diseases ruled out HIV, Hepatitis B&C, EBV, CMV, stongyloides, leishmaniasis, syphilis and malaria. Daily pyrexia persisted, and she developed a progressive pancytopenia, rash, mucositis and a rising ferritin up to 30000. …”
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6216por Borghi, Sergio M., Fattori, Victor, Pinho-Ribeiro, Felipe A., Domiciano, Talita P., Miranda-Sapla, Milena M., Zaninelli, Tiago H., Casagrande, Rubia, Pinge-Filho, Phileno, Pavanelli, Wander R., Alves-Filho, Jose C., Cunha, Fernando Q., Cunha, Thiago M., Verri, Waldiceu A.“…BACKGROUND: The cellular and molecular pathophysiological mecha\nisms of pain processing in neglected parasitic infections such as leishmaniasis remain unknown. The present study evaluated the participation of spinal cord glial cells in the pathophysiology of pain induced by Leishmania amazonensis infection in BALB/c mice. …”
Publicado 2019
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6217por Bottieau, Emmanuel, Van Duffel, Lukas, El Safi, Sayda, Koirala, Kanika Deshpande, Khanal, Basudha, Rijal, Suman, Bhattarai, Narayan Raj, Phe, Thong, Lim, Kruy, Mukendi, Deby, Kalo, Jean-Roger Lilo, Lutumba, Pascal, Barbé, Barbara, Jacobs, Jan, Van Esbroeck, Marjan, Foqué, Nikki, Tsoumanis, Achilleas, Parola, Philippe, Yansouni, Cedric P., Boelaert, Marleen, Verdonck, Kristien, Chappuis, François“…Participants underwent a reference diagnostic workup targeting a pre-established list of 12 epidemiologically relevant priority infections (i.e., malaria, tuberculosis, HIV, enteric fever, leptospirosis, rickettsiosis, brucellosis, melioidosis, relapsing fever, visceral leishmaniasis, human African trypanosomiasis, amebic liver abscess). …”
Publicado 2022
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6218por Bletter, Nathaniel“…A prerequisite to this hypothesis, the idea that empirical testing in traditional medicine will lead to choosing similar medicinal plants and therefore the medicinal flora of two distant cultures will prove to be more similar than their general flora, is tested using resampling statistics on cross-cultural field data of the plants used by the Malinké of Mali and the Asháninka of Peru to treat the diseases malaria, African sleeping sickness, Chagas' disease, leishmaniasis, diabetes, eczema, asthma, and uterine fibroids. …”
Publicado 2007
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6219por Janapala, Rajesh naldu, jayaraj, joseph, Rass, bayan, Zarghamravanbakhsh, Paria, Sachmechi, issac“…Amphotericin B is used to treat a wide range of invasive systemic fungal infections and some protozoan infections (visceral leishmaniasis). Amphotericin B is not the first line of choice in most fungal infections due to its well-known severe side effects. …”
Publicado 2020
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