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12411662. Pushing the Dose: Miltefosine Treatment for a Supersized American with Cutaneous Leishmaniasispor Aronson, Naomi E, Roseboom, Ignace, Digby, Michael, Bravos, Christina, Selig, Daniel, Farmer, Aaron, AM van Thiel, Pieter-Paul, Dorlo, Thomas“…BACKGROUND: Miltefosine (Profounda, FL) is an oral alkylphospholipid drug which is approved by the Food and Drug Administration for the treatment of some species of New World cutaneous leishmaniasis. The maximal daily recommended dosage is 50 mg t.i.d for 28 days; yet there is some evidence that doses <2.5 mg/kg/day may be associated with lesser efficacy. …”
Publicado 2019
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1242por Jaafari, Mahmoud Reza, Hatamipour, Mahdi, Alavizadeh, Seyedeh Hoda, Abbasi, Azam, Saberi, Zahra, Rafati, Sima, Taslimi, Yasaman, Mohammadi, Akram Miramin, Khamesipour, AliMaterias: “…Includes articles from the special issue “Novel therapies for cutaneous leishmaniasis”, pp. 106 - 179…”
Publicado 2019
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1243por Moreno, Esther, Calvo, Alba, Schwartz, Juana, Navarro-Blasco, Iñigo, González-Peñas, Elena, Sanmartín, Carmen, Irache, Juan Manuel, Espuelas, Socorro“…The oral administration of dapsone (DAP) for the treatment of cutaneous leishmaniasis (CL) is effective, although serious hematological side effects limit its use. …”
Publicado 2019
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1244por Yaghoobi-Ershadi, Mohammad Reza, Akhavan, Amir Ahmad, Shirzadi, Mohammad Reza, Rassi, Yavar, Khamesipour, Ali, Hanafi-Bojd, Ahmad Ali, Vatandoost, Hassan“…BACKGROUND: Leishmaniasis represents the important public health problem in the world. …”
Publicado 2019
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1245por Sakhaei, Shahriar, Darrudi, Reza, Motaarefi, Hossein, Sadagheyani, Hassan Ebrahimpour“…BACKGROUND: Cutaneous Leishmaniasis (CL) isn’t a lethal disease, but it has always been taken into consideration due to more involvement of patients with skin ulcers and its long-term treatment. …”
Publicado 2019
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1246por Ishizuka, Kanna, Fujii, Wataru, Azuma, Natsuho, Mizobuchi, Haruka, Morimoto, Ayako, Sanjoba, Chizu, Matsumoto, Yoshitsugu, Goto, Yasuyuki“…In this study, to examine the pathological involvement of MRP14 during cutaneous and visceral leishmaniasis, wild-type (WT) and MRP14 knockout (MRP14KO) mice were infected with Leishmania major and L. donovani. …”
Publicado 2020
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1247por Zijlstra, Eduard E., Liberton, Niels, Musa, Ahmed M., te Slaa, Sjoerd, Wolff, Jan“…Post–kala-azar dermal leishmaniasis may occur after successful treatment of visceral leishmaniasis and is characterized by macules, papules, or nodules in the skin, with varying size. …”
Publicado 2020
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1248por Gherbi, Roumaissa, Bounechada, Mustapha, Latrofa, Maria Stefania, Annoscia, Giada, Tarallo, Viviana Domenica, Dantas-Torres, Filipe, Otranto, Domenico“…Cutaneous leishmaniasis is a disease caused by various Leishmania spp., which are transmitted by phlebotomine sand flies. …”
Publicado 2020
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1249“…INTRODUCTION: Leishmaniasis is a zoonotic disease which is caused by protozoan parasites of the genus Leishmania. …”
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1250por Santos, F.N., Borja-Cabrera, G.P., Miyashiro, L.M., Grechi, J., Reis, A.B., Moreira, M.A.B., Martins Filho, O.A., Luvizotto, M.C.R., Menz, I., Pessôa, L.M., Gonçalves, P.R., Palatnik, M., Palatnik-de-Sousa, C.B.“…In order to assess the immunotherapeutic potential on canine visceral leishmaniasis of the Leishmune(®) vaccine, formulated with an increased adjuvant concentration (1 mg of saponin rather than 0.5 mg), 24 mongrel dogs were infected with Leishmania (L.) chagasi. …”
Publicado 2007
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1251por Molina, Ricardo, Jiménez, Maribel, García-Martínez, Jesús, San Martín, Juan Víctor, Carrillo, Eugenia, Sánchez, Carmen, Moreno, Javier, Alves, Fabiana, Alvar, Jorge“…It is noteworthy that the HIV / L. infantum coinfected patient with asymptomatic leishmaniasis was easily infectious to sand flies for a long time, despite being under continuous prophylaxis for leishmaniasis. …”
Publicado 2020
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1252por Pathirage, Dulani R. K., Karunaratne, S. H. P. Parakrama, Senanayake, Sanath C., Karunaweera, Nadira D.“…BACKGROUND: Leishmania donovani-induced and sand fly-transmitted leishmaniasis is a growing health problem in Sri Lanka. …”
Publicado 2020
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1253por Santarém, Nuno, Sousa, Susana, Amorim, Célia G., de Carvalho, Nuno Lima, de Carvalho, Hugo Lima, Felgueiras, Óscar, Brito, Margarida, da Silva, Anabela CordeiroEnlace del recurso
Publicado 2020
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1254por de Sousa Gonçalves, Rafaela, Alves de Pinho, Flaviane, Dinis-Oliveira, Ricardo Jorge, Azevedo, Rui, Gaifem, Joana, Farias Larangeira, Daniela, Ramos-Sanchez, Eduardo Milton, Goto, Hiro, Silvestre, Ricardo, Barrouin-Melo, Stella Maria“…Prediction parameters of possible outcomes of canine leishmaniasis (CanL) therapy might help with therapeutic decisions and animal health care. …”
Publicado 2020
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1256por Hakkour, Maryam, Hmamouch, Asmae, Mahmoud El Alem, Mohamed, Bouyahya, Abdelhakim, Balahbib, Abdelaali, EL Khazraji, Abdelhak, Fellah, Hajiba, Sadak, Abderrahim, Sebti, Faiza“…BACKGROUND: Human leishmaniasis, both visceral and cutaneous, has been reported in Morocco for centuries and constitutes a serious public health problem. …”
Publicado 2020
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1257por Miramin-Mohammadi, Akram, Javadi, Amir, Eskandari, Seyed Ebrahim, Mortazavi, Hossein, Rostami, Mahmoud Nateghi, Khamesipour, Ali“…In this study, the Th1/Th2 cytokine profile in cutaneous leishmaniasis (CL) is evaluated. MATERIALS AND METHODS: This study was carried out in leishmaniasis clinic of CRTSDL, TUMS, during March 2018 to March 2019. …”
Publicado 2020
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1258“…Cancer, malaria, and leishmaniasis remain the deadly diseases around the world although several strategies of treatment have been developed. …”
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1259por Donato, Lucas Edel, de Freitas, Lúcia Rolim Santana, Duarte, Elisabeth Carmen, Romero, Gustavo Adolfo Sierra“…INTRODUCTION: It is believed that delays in diagnosis and treatment of Visceral Leishmaniasis (VL) contribute significantly to the burden of VL lethality in Brazil. …”
Publicado 2020
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1260por Khanra, Supriya, Juin, Subir Kumar, Jawed, Junaid Jibran, Ghosh, Sweta, Dutta, Shreyasi, Nabi, Shaik Abdul, Dash, Jyotirmayee, Dasgupta, Dipak, Majumdar, Subrata, Banerjee, Rahul“…BACKGROUND: Treatment failure and resistance to the commonly used drugs remains a major obstacle for successful chemotherapy against visceral leishmaniasis (VL). Since the development of novel therapeutics involves exorbitant costs, the effectiveness of the currently available antitrypanosomatid drug suramin has been investigated as an antileishmanial, specifically for VL,in vitro and in animal model experiments. …”
Publicado 2020
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