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1361
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1363por Pandey, Krishna, Sinha, Prabhat Kumar, Rabidas, Vidya, Kumar, Nawin, Bimal, Sanjiva, Verma, Neena, Lal, Chandrasekhar, Das, Pradeep“…BACKGROUND: Visceral leishmaniasis is caused by a protozoan parasite, Leishmania donovani and transmitted by the bite of female sandflies. …”
Publicado 2008
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1364por Verçosa, BLA, Lemos, CM, Mendonça, IL, Silva, SMMS, de Carvalho, SM, Goto, H, Costa, FAL“…BACKGROUND: Visceral leishmaniasis in Brazil is caused by the protozoan Leishmania (Leishmania) chagasi and it is transmitted by sandfly of the genus Lutzomyia. …”
Publicado 2008
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1365por Modolell, Manuel, Choi, Beak-San, Ryan, Robert O., Hancock, Maggie, Titus, Richard G., Abebe, Tamrat, Hailu, Asrat, Müller, Ingrid, Rogers, Matthew E., Bangham, Charles R. M., Munder, Markus, Kropf, Pascale“…The balance between T helper (Th) 1 and Th2 cell responses is a major determinant of the outcome of experimental leishmaniasis, but polarized Th1 or Th2 responses are not sufficient to account for healing or nonhealing. …”
Publicado 2009
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1366
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1367por Mugasa, Claire M, Laurent, Thierry, Schoone, Gerard J, Basiye, Frank L, Saad, Alfarazdeg A, el Safi, Sayda, Kager, Piet A, Schallig, Henk DFH“…In the present study isothermal, nucleic acid sequence based amplification (NASBA) was coupled to oligochromatography (OC) to develop a simplified detection method for the diagnosis of leishmaniasis. NASBA-OC, detecting Leishmania RNA, was evaluated using clinical samples from visceral leishmaniasis patients from East Africa (n = 30) and cutaneous leishmaniasis from South America (n = 70) and appropriate control samples. …”
Publicado 2010
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1368por Saad, Alfarazdeg A., Ahmed, Nuha G., Osman, Osman S., Al-Basheer, Ahmed Almustafa, Hamad, Awad, Deborggraeve, Stijn, Büscher, Philippe, Schoone, Gerard J., Schallig, Henk D., Laurent, Thierry, Haleem, Ahmed, Osman, Omran F., Eltom, Ahmed Mohamedain, Elbashir, Mustafa I., El-Safi, Sayda“…We here present the phase II evaluation of both tests for diagnosis of visceral leishmaniasis (VL), cutaneous leishmaniasis (CL) and post kala-azar dermal leishmaniasis (PKDL) in Sudan. …”
Publicado 2010
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1369por Nateghi Rostami, Mahmoud, Keshavarz, Hossein, Edalat, Rosita, Sarrafnejad, Abdolfattah, Shahrestani, Tahereh, Mahboudi, Fereidoun, Khamesipour, Ali“…BACKGROUND: In human leishmaniasis Th1/Th2 dichotomy similar to murine model is not clearly defined and surrogate marker(s) of protection is not yet known. …”
Publicado 2010
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1370por Guerra, Jorge Augusto de Oliveira, Prestes, Suzane Ribeiro, Silveira, Henrique, Coelho, Leila Inês de Aguiar Raposo Câmara, Gama, Pricila, Moura, Aristoteles, Amato, Valdir, Barbosa, Maria das Graças Vale, Ferreira, Luiz Carlos de Lima“…BACKGROUND: Leishmania (Viannia) braziliensis is a parasite recognized as the most important etiologic agent of mucosal leishmaniasis (ML) in the New World. In Amazonia, seven different species of Leishmania, etiologic agents of human Cutaneous Leishmaniasis, have been described. …”
Publicado 2011
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1371por Santos-Oliveira, Joanna R., Regis, Eduardo G., Leal, Cássia R. B., Cunha, Rivaldo V., Bozza, Patrícia T., Da-Cruz, Alda M.“…BACKGROUND: Visceral leishmaniasis (VL) is characterized by parasite-specific immunosuppression besides an intense pro-inflammatory response. …”
Publicado 2011
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1372por Perry, Meghan R., Wyllie, Susan, Prajapati, Vijay Kumar, Feldmann, Joerg, Sundar, Shyam, Boelaert, Marleen, Fairlamb, Alan H.Enlace del recurso
Publicado 2011
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1373“…The spatial-temporal analysis of the abundance of insects, vectors of tegumentary leishmaniasis (TL) and visceral leishmaniasis (VL), was performed in Argentina using spatial-temporal increasing scales. …”
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1374por Maroof, Asher, Brown, Najmeeyah, Smith, Barbara, Hodgkinson, Michael R., Maxwell, Alice, Losch, Florian O., Fritz, Ulrike, Walden, Peter, Lacey, Charles N. J., Smith, Deborah F., Aebischer, Toni, Kaye, Paul M.“…Therapeutic vaccines, when used alone or in combination therapy with antileishmanial drugs, may have an important place in the control of a variety of forms of human leishmaniasis. Here, we describe the development of an adenovirus-based vaccine (Ad5-KH) comprising a synthetic haspb gene linked to a kmp11 gene via a viral 2A sequence. …”
Publicado 2012
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1375por Mohebali, M, Malmasi, A, Hajjaran, H, Jamshidi, S, Akhoundi, B, Rezaei, M, Janitabar, S, Zarei, H, Charehdar, S“…A 5-month old puppy with muco-cutaneous lesions in the chin, around lips and eyes was examined physically and microscopically for leishmaniasis. Muco-cutaneous lesions containing a large number of amastigotes of Leishmania spp. were observed. …”
Publicado 2011
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1376por Quilez, Javier, Martínez, Verónica, Woolliams, John A., Sanchez, Armand, Pong-Wong, Ricardo, Kennedy, Lorna J., Quinnell, Rupert J., Ollier, William E. R., Roura, Xavier, Ferrer, Lluís, Altet, Laura, Francino, Olga“…BACKGROUND: The current disease model for leishmaniasis suggests that only a proportion of infected individuals develop clinical disease, while others are asymptomatically infected due to immune control of infection. …”
Publicado 2012
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1377por Toumi, Amine, Chlif, Sadok, Bettaieb, Jihene, Alaya, Nissaf Ben, Boukthir, Aicha, Ahmadi, Zaher E., Salah, Afif Ben“…BACKGROUND: Old world Zoonotic Cutaneous Leishmaniasis (ZCL) is a vector-borne human disease caused by Leishmania major, a unicellular eukaryotic parasite transmitted by pool blood-feeding sand flies mainly to wild rodents, such as Psammomys obesus. …”
Publicado 2012
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1378“…BACKGROUND: Most available drugs against visceral leishmaniasis are toxic, and growing limitations in available chemotherapeutic strategies due to emerging resistant strains and lack of an effective vaccine against visceral leishmaniasis deepens the crisis. …”
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1379por França-Costa, Jaqueline, Wanderley, João Luiz Mendes, Deolindo, Poliana, Zarattini, Jessica B., Costa, Jackson, Soong, Lynn, Barcinski, Marcello André, Barral, Aldina, Borges, Valeria M.“…Diffuse cutaneous leishmaniasis (DCL) is a rare clinical manifestation of leishmaniasis, characterized by an inefficient parasite-specific cellular response and heavily parasitized macrophages. …”
Publicado 2012
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1380por Alizadeh, R, Hooshyar, H, Bandehpor, M, Arbabi, M, Kazemi, F, Talari, A, Kazemi, B“…BACKGROUND: Cutaneous leishmaniasis is still a health problem in many rural and urban regions of Iran and drug resistance has emerged as a major impediment in the treatment of leishmaniasis. …”
Publicado 2011
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