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Mostrando 181 - 200 Resultados de 880 Para Buscar '"lepra"', tiempo de consulta: 0.18s Limitar resultados
  1. 181
    “…OBJECTIVES: Describe the impact of MDT over Mycobacterium leprae viability in patient’s oral and nasal mucosa along treatment. …”
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    Heterogeneous persistence of Mycobacterium leprae in oral and nasal mucosa of multibacillary patients during multidrug therapy
  2. 182
    “…BACKGROUND: M. leprae preferentially infects Schwann cells (SCs) in the peripheral nerves leading to nerve damage and irreversible disability. …”
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    Single-cell sequencing analysis reveals development and differentiation trajectory of Schwann cells manipulated by M. leprae
  3. 183
    “…BACKGROUND: Mycobacterium leprae (ML) is the pathogen that causes leprosy, which has a long history and still exists today. …”
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    Highly sensitive and rapid determination of Mycobacterium leprae based on real-time multiple cross displacement amplification
  4. 184
    “…BACKGROUND: It has been amply described that levels of IgM antibodies against Mycobacterium leprae (M. leprae) phenolic glycolipid I (PGL-I) correlate strongly with the bacterial load in an infected individual. …”
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    Field-friendly anti-PGL-I serosurvey in children to monitor Mycobacterium leprae transmission in Bihar, India
  5. 185
    “…During recent years, comparative genomic analysis has allowed the identification of Mycobacterium leprae-specific genes with potential application for the diagnosis of leprosy. …”
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    Pathogen-Specific Epitopes as Epidemiological Tools for Defining the Magnitude of Mycobacterium leprae Transmission in Areas Endemic for Leprosy
  6. 186
    “…Leprosy, caused by Mycobacterium leprae, is an important infectious disease that is still endemic in many countries around the world, including Brazil. …”
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    Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
  7. 187
    “…Mycobacterium leprae, etiologic agent of leprosy, is propagated in athymic nude mouse footpads (FPs). …”
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    Semi-automated protocol for purification of Mycobacterium leprae from tissues using the gentleMACS™ Octo Dissociator
  8. 188
    “…DNA was extracted from the surfaces of bones showing osteological signs of leprosy. Known M. leprae polymorphisms were PCR amplified and Sanger sequenced, while draft genomes were generated by enriching for M. leprae DNA, and Illumina sequencing. …”
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    Mycobacterium leprae genomes from a British medieval leprosy hospital: towards understanding an ancient epidemic
  9. 189
    “…Here, we determined the contribution of the MAC to nerve damage caused by Mycobacterium leprae and its components in mouse. Furthermore, we studied the association between MAC and the key M. leprae component lipoarabinomannan (LAM) in nerve biopsies of leprosy patients. …”
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    M. leprae components induce nerve damage by complement activation: identification of lipoarabinomannan as the dominant complement activator
  10. 190
    “…Two M. leprae principal clusters were found: haplotypes C54 and T45. …”
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    Human Genetic Ancestral Composition Correlates with the Origin of Mycobacterium leprae Strains in a Leprosy Endemic Population
  11. 191
    “…BACKGROUND: The detection of live Mycobacterium leprae in soil and animals other than humans suggests that the environment plays a role in the transmission of leprosy. …”
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    Natural environmental water sources in endemic regions of northeastern Brazil are potential reservoirs of viable Mycobacterium leprae
  12. 192
    Publicado 1835
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    A Practical Treatise on Lepra Vulgaris; to Which Are Added, Observations on the Treatment of Some of the Local Varieties of Psoriasis
  13. 193
    “…Lepra reaction may lead to exposure of neural antigens, resulting in autoimmune mechanism and demyelination of peripheral nerves.…”
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    Guillain–Barre Syndrome: A Rare Presentation of Borderline Tuberculoid Leprosy with Type 1 Lepra Reaction
  14. 194
    “…Given that M. leprae-induced type I interferon (IFN) inhibited monocyte activation, we blocked the type I IFN receptor (IFNAR), revealing the intrinsic capacity of monocytes to recognize M. leprae and upregulate CYP27B1. …”
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    Intrinsic activation of the vitamin D antimicrobial pathway by M. leprae infection is inhibited by type I IFN
  15. 195
    “…The detection of specific point mutations in folP1 that encode dihydropteroate synthases (DHPS) is used exclusively to identify dapsone resistant strains of Mycobacterium leprae. The purpose of this study was to test for the presence of folP1 mutations in M. leprae strains isolated from patients residing in Papua Island, Indonesia who responded less effectively to dapsone. …”
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    A new Mycobacterium leprae dihydropteroate synthase variant (V39I) from Papua, Indonesia
  16. 196
    “…However, the impossibility of growing Mycobacterium leprae in axenic media has historically impaired assessments of M. leprae resistance, a parameter only recently detectable through molecular methods. …”
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    Emergence and Transmission of Drug-/Multidrug-resistant Mycobacterium leprae in a Former Leprosy Colony in the Brazilian Amazon
  17. 197
    “…Leprosy, caused by Mycobacterium leprae, has plagued humanity for thousands of years and continues to cause morbidity, disability and stigmatization in two to three million people today. …”
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    GSMN-ML- a genome scale metabolic network reconstruction of the obligate human pathogen Mycobacterium leprae
  18. 198
    “…BACKGROUND: The causative agents of leprosy are the well-known Mycobacterium leprae and the newly discovered Mycobacterium lepromatosis. …”
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    Identification of Mycobacterium leprae and Mycobacterium lepromatosis in Formalin-Fixed and Paraffin-Embedded Skin Samples from Mexico
  19. 199
    “…BACKGROUND: Mycobacterium leprae and Mycobacterium lepromatosis are gram-positive bacterial pathogens and the causative agents of leprosy in humans across the world. …”
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    Reverse vaccinology and subtractive genomics approaches for identifying common therapeutics against Mycobacterium leprae and Mycobacterium lepromatosis
  20. 200
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    Corrigendum: Reductive Power Generated by Mycobacterium leprae Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis
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