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1por Luethi, Nora, Cioccari, Luca, Crisman, Marco, Bellomo, Rinaldo, Eastwood, Glenn M., Mårtensson, Johan“…BACKGROUND: It is uncertain whether liberal glucose control in critically ill diabetic patients leads to increased ketone production and ketoacidosis. …”
Publicado 2016
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2por Myles, Paul, Bellomo, Rinaldo, Corcoran, Tomas, Forbes, Andrew, Wallace, Sophie, Peyton, Philip, Christophi, Chris, Story, David, Leslie, Kate, Serpell, Jonathan, McGuinness, Shay, Parke, Rachel“…The expected fluid volumes in the first 24 hour from the start of surgery in restrictive and liberal groups were ≤3.0 L and ≥5.4 L, respectively. …”
Publicado 2017
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3por Poole, Alexis P., Finnis, Mark E., Anstey, James, Bellomo, Rinaldo, Bihari, Shailesh, Biradar, Vishwanath, Doherty, Sarah, Eastwood, Glenn, Finfer, Simon, French, Craig J., Ghosh, Angaj, Heller, Simon, Horowitz, Michael, Kar, Palash, Kruger, Peter S., Maiden, Matthew J., Mårtensson, Johan, McArthur, Colin J., McGuinness, Shay P., Secombe, Paul J., Tobin, Antony E., Udy, Andrew A., Young, Paul J., Deane, Adam M.“…Patients will be randomised 1:1 to liberal blood glucose (target 10.0–14.0 mmol/L) or usual care (target 6.0–10.0 mmol/L). …”
Publicado 2023
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4por Young, Paul J., Arabi, Yaseen M., Bagshaw, Sean M., Bellomo, Rinaldo, Fujii, Tomoko, Haniffa, Rashan, Hodgson, Carol L., Vijayaraghavan, Bharath Kumar Tirupakuzhi, Litton, Edward, Mackle, Diane, Nichol, Alistair D., Kasza, Jessica“…Background: The effect of conservative versus liberal oxygen therapy on 90-day in-hospital mortality in patients who require unplanned invasive mechanical ventilation in an intensive care unit (ICU) is uncertain and will be evaluated in the mega randomised registry trial research program (Mega-ROX). …”
Publicado 2023
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5por Young, Paul J., Hodgson, Carol L., Mackle, Diane, Mather, Anne M., Beasley, Richard, Bellomo, Rinaldo, Bernard, Stephen, Brickell, Kathy, Deane, Adam M., Eastwood, Glenn, Finfer, Simon, Higgins, Alisa M., Hunt, Anna, Lawrence, Cassie, Linke, Natalie J., Litton, Edward, McDonald, Christine F., Moore, James, Nichol, Alistair D., Olatunji, Shaanti, Parke, Rachael L., Peake, Sandra, Secombe, Paul, Seppelt, Ian M., Turner, Anne, Trapani, Tony, Udy, Andrew, Kasza, Jessica“…BACKGROUND: The effect of conservative vs. liberal oxygen therapy on outcomes of intensive care unit (ICU) patients with hypoxic ischaemic encephalopathy (HIE) is uncertain and will be evaluated in the Low Oxygen Intervention for Cardiac Arrest injury Limitation (LOGICAL) trial. …”
Publicado 2023
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6por Burrell, Aidan, Ng, Sze, Ottosen, Kelly, Bailey, Michael, Buscher, Hergen, Fraser, John, Udy, Andrew, Gattas, David, Totaro, Richard, Bellomo, Rinaldo, Forrest, Paul, Martin, Emma, Reid, Liadain, Ziegenfuss, Marc, Eastwood, Glenn, Higgins, Alisa, Hodgson, Carol, Litton, Edward, Nair, Priya, Orford, Neil, Pellegrino, Vince, Shekar, Kiran, Trapani, Tony, Pilcher, David“…CONCLUSIONS: This paper details the protocol and statistical analysis plan for the BLENDER trial, a registry-embedded, multicentre interventional trial comparing liberal and conservative oxygenation strategies in VA ECMO.…”
Publicado 2023
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7por Mårtensson, Johan, Cutuli, Salvatore, Yanase, Fumitaka, Ancona, Paolo, Toh, Lisa, Osawa, Eduardo, Bellomo, Rinaldo“…CONCLUSIONS: In our cohort of ICU patients with type 2 diabetes receiving liberal glycemic control, CGM showed acceptable accuracy and was associated with a reduction in blood gas sampling frequency without compromising glucose control. …”
Publicado 2022
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8por Crisman, Marco, Lucchetta, Luca, Luethi, Nora, Cioccari, Luca, Lam, Que, Eastwood, Glenn M., Bellomo, Rinaldo, Mårtensson, Johan“…METHODS: We prospectively enrolled a cohort of 45 critically ill patients with type 2 diabetes managed according to a liberal glucose protocol (target blood glucose 10–14 mmol/l). …”
Publicado 2017
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9por Young, Paul, Mackle, Diane, Bellomo, Rinaldo, Bailey, Michael, Beasley, Richard, Deane, Adam, Eastwood, Glenn, Finfer, Simon, Freebairn, Ross, King, Victoria, Linke, Natalie, Litton, Edward, McArthur, Colin, McGuinness, Shay, Panwar, Rakshit“…PURPOSE: Liberal use of oxygen may contribute to secondary brain injury in patients with hypoxic-ischaemic encephalopathy (HIE). …”
Publicado 2020
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10por Keijzers, Gerben, Macdonald, Stephen PJ, Udy, Andrew A, Arendts, Glenn, Bailey, Michael, Bellomo, Rinaldo, Blecher, Gabriel E, Burcham, Jonathon, Coggins, Andrew R, Delaney, Anthony, Fatovich, Daniel M, Fraser, John F, Harley, Amanda, Jones, Peter, Kinnear, Frances B, May, Katya, Peake, Sandra, Taylor, David McD, Williams, Patricia“…CONCLUSION: Current resuscitation practice in patients with sepsis and hypotension varies widely and occupies the spectrum between a restricted volume/earlier vasopressor and liberal fluid/later vasopressor strategy.…”
Publicado 2020
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11por Macdonald, Stephen P. J., Taylor, David McD, Keijzers, Gerben, Arendts, Glenn, Fatovich, Daniel M., Kinnear, Frances B., Brown, Simon G. A., Bellomo, Rinaldo, Burrows, Sally, Fraser, John F., Litton, Edward, Ascencio-Lane, Juan Carlos, Anstey, Matthew, McCutcheon, David, Smart, Lisa, Vlad, Ioana, Winearls, James, Wibrow, Bradley“…There is currently equipoise regarding liberal or restricted fluid-volume resuscitation as first-line treatment for sepsis-related hypotension. …”
Publicado 2017
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12por Mårtensson, Johan, Cutuli, Salvatore Lucio, Osawa, Eduardo A., Yanase, Fumitaka, Toh, Lisa, Cioccari, Luca, Luethi, Nora, Maeda, Akinori, Bellomo, Rinaldo“…METHODS: We included 18 ICU patients with type 2 diabetes receiving empagliflozin (10 mg daily) and insulin to target glucose range of 10–14 mmol/l according to our liberal glucose control protocol for patients with diabetes (treatment group). …”
Publicado 2023
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13por Tumlin, James A., Murugan, Raghavan, Deane, Adam M., Ostermann, Marlies, Busse, Laurence W., Ham, Kealy R., Kashani, Kianoush, Szerlip, Harold M., Prowle, John R., Bihorac, Azra, Finkel, Kevin W., Zarbock, Alexander, Forni, Lui G., Lynch, Shannan J., Jensen, Jeff, Kroll, Stew, Chawla, Lakhmir S., Tidmarsh, George F., Bellomo, Rinaldo“…CONCLUSIONS: In patients with acute kidney injury requiring renal replacement therapy at study drug initiation, 28-day survival and mean arterial pressure response were higher, and rate of renal replacement therapy liberation was greater in the angiotensin II group versus the placebo group. …”
Publicado 2018
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