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1av Luethi, Nora, Cioccari, Luca, Crisman, Marco, Bellomo, Rinaldo, Eastwood, Glenn M., Mårtensson, Johan“…BACKGROUND: It is uncertain whether liberal glucose control in critically ill diabetic patients leads to increased ketone production and ketoacidosis. …”
Publicerad 2016
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2av Myles, Paul, Bellomo, Rinaldo, Corcoran, Tomas, Forbes, Andrew, Wallace, Sophie, Peyton, Philip, Christophi, Chris, Story, David, Leslie, Kate, Serpell, Jonathan, McGuinness, Shay, Parke, Rachel“…The expected fluid volumes in the first 24 hour from the start of surgery in restrictive and liberal groups were ≤3.0 L and ≥5.4 L, respectively. …”
Publicerad 2017
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3av Poole, Alexis P., Finnis, Mark E., Anstey, James, Bellomo, Rinaldo, Bihari, Shailesh, Biradar, Vishwanath, Doherty, Sarah, Eastwood, Glenn, Finfer, Simon, French, Craig J., Ghosh, Angaj, Heller, Simon, Horowitz, Michael, Kar, Palash, Kruger, Peter S., Maiden, Matthew J., Mårtensson, Johan, McArthur, Colin J., McGuinness, Shay P., Secombe, Paul J., Tobin, Antony E., Udy, Andrew A., Young, Paul J., Deane, Adam M.“…Patients will be randomised 1:1 to liberal blood glucose (target 10.0–14.0 mmol/L) or usual care (target 6.0–10.0 mmol/L). …”
Publicerad 2023
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4av Young, Paul J., Arabi, Yaseen M., Bagshaw, Sean M., Bellomo, Rinaldo, Fujii, Tomoko, Haniffa, Rashan, Hodgson, Carol L., Vijayaraghavan, Bharath Kumar Tirupakuzhi, Litton, Edward, Mackle, Diane, Nichol, Alistair D., Kasza, Jessica“…Background: The effect of conservative versus liberal oxygen therapy on 90-day in-hospital mortality in patients who require unplanned invasive mechanical ventilation in an intensive care unit (ICU) is uncertain and will be evaluated in the mega randomised registry trial research program (Mega-ROX). …”
Publicerad 2023
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5av Young, Paul J., Hodgson, Carol L., Mackle, Diane, Mather, Anne M., Beasley, Richard, Bellomo, Rinaldo, Bernard, Stephen, Brickell, Kathy, Deane, Adam M., Eastwood, Glenn, Finfer, Simon, Higgins, Alisa M., Hunt, Anna, Lawrence, Cassie, Linke, Natalie J., Litton, Edward, McDonald, Christine F., Moore, James, Nichol, Alistair D., Olatunji, Shaanti, Parke, Rachael L., Peake, Sandra, Secombe, Paul, Seppelt, Ian M., Turner, Anne, Trapani, Tony, Udy, Andrew, Kasza, Jessica“…BACKGROUND: The effect of conservative vs. liberal oxygen therapy on outcomes of intensive care unit (ICU) patients with hypoxic ischaemic encephalopathy (HIE) is uncertain and will be evaluated in the Low Oxygen Intervention for Cardiac Arrest injury Limitation (LOGICAL) trial. …”
Publicerad 2023
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6av Burrell, Aidan, Ng, Sze, Ottosen, Kelly, Bailey, Michael, Buscher, Hergen, Fraser, John, Udy, Andrew, Gattas, David, Totaro, Richard, Bellomo, Rinaldo, Forrest, Paul, Martin, Emma, Reid, Liadain, Ziegenfuss, Marc, Eastwood, Glenn, Higgins, Alisa, Hodgson, Carol, Litton, Edward, Nair, Priya, Orford, Neil, Pellegrino, Vince, Shekar, Kiran, Trapani, Tony, Pilcher, David“…CONCLUSIONS: This paper details the protocol and statistical analysis plan for the BLENDER trial, a registry-embedded, multicentre interventional trial comparing liberal and conservative oxygenation strategies in VA ECMO.…”
Publicerad 2023
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7av Mårtensson, Johan, Cutuli, Salvatore, Yanase, Fumitaka, Ancona, Paolo, Toh, Lisa, Osawa, Eduardo, Bellomo, Rinaldo“…CONCLUSIONS: In our cohort of ICU patients with type 2 diabetes receiving liberal glycemic control, CGM showed acceptable accuracy and was associated with a reduction in blood gas sampling frequency without compromising glucose control. …”
Publicerad 2022
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8av Crisman, Marco, Lucchetta, Luca, Luethi, Nora, Cioccari, Luca, Lam, Que, Eastwood, Glenn M., Bellomo, Rinaldo, Mårtensson, Johan“…METHODS: We prospectively enrolled a cohort of 45 critically ill patients with type 2 diabetes managed according to a liberal glucose protocol (target blood glucose 10–14 mmol/l). …”
Publicerad 2017
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9av Young, Paul, Mackle, Diane, Bellomo, Rinaldo, Bailey, Michael, Beasley, Richard, Deane, Adam, Eastwood, Glenn, Finfer, Simon, Freebairn, Ross, King, Victoria, Linke, Natalie, Litton, Edward, McArthur, Colin, McGuinness, Shay, Panwar, Rakshit“…PURPOSE: Liberal use of oxygen may contribute to secondary brain injury in patients with hypoxic-ischaemic encephalopathy (HIE). …”
Publicerad 2020
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10av Keijzers, Gerben, Macdonald, Stephen PJ, Udy, Andrew A, Arendts, Glenn, Bailey, Michael, Bellomo, Rinaldo, Blecher, Gabriel E, Burcham, Jonathon, Coggins, Andrew R, Delaney, Anthony, Fatovich, Daniel M, Fraser, John F, Harley, Amanda, Jones, Peter, Kinnear, Frances B, May, Katya, Peake, Sandra, Taylor, David McD, Williams, Patricia“…CONCLUSION: Current resuscitation practice in patients with sepsis and hypotension varies widely and occupies the spectrum between a restricted volume/earlier vasopressor and liberal fluid/later vasopressor strategy.…”
Publicerad 2020
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11av Macdonald, Stephen P. J., Taylor, David McD, Keijzers, Gerben, Arendts, Glenn, Fatovich, Daniel M., Kinnear, Frances B., Brown, Simon G. A., Bellomo, Rinaldo, Burrows, Sally, Fraser, John F., Litton, Edward, Ascencio-Lane, Juan Carlos, Anstey, Matthew, McCutcheon, David, Smart, Lisa, Vlad, Ioana, Winearls, James, Wibrow, Bradley“…There is currently equipoise regarding liberal or restricted fluid-volume resuscitation as first-line treatment for sepsis-related hypotension. …”
Publicerad 2017
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12av Mårtensson, Johan, Cutuli, Salvatore Lucio, Osawa, Eduardo A., Yanase, Fumitaka, Toh, Lisa, Cioccari, Luca, Luethi, Nora, Maeda, Akinori, Bellomo, Rinaldo“…METHODS: We included 18 ICU patients with type 2 diabetes receiving empagliflozin (10 mg daily) and insulin to target glucose range of 10–14 mmol/l according to our liberal glucose control protocol for patients with diabetes (treatment group). …”
Publicerad 2023
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13av Tumlin, James A., Murugan, Raghavan, Deane, Adam M., Ostermann, Marlies, Busse, Laurence W., Ham, Kealy R., Kashani, Kianoush, Szerlip, Harold M., Prowle, John R., Bihorac, Azra, Finkel, Kevin W., Zarbock, Alexander, Forni, Lui G., Lynch, Shannan J., Jensen, Jeff, Kroll, Stew, Chawla, Lakhmir S., Tidmarsh, George F., Bellomo, Rinaldo“…CONCLUSIONS: In patients with acute kidney injury requiring renal replacement therapy at study drug initiation, 28-day survival and mean arterial pressure response were higher, and rate of renal replacement therapy liberation was greater in the angiotensin II group versus the placebo group. …”
Publicerad 2018
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