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2521“…While a radical change in the implant treatment paradigm has taken place in some countries, in other countries, dentists try hard to keep their work area free of implants or to deliver them only as a last resort. Liberating patients from the burdens of their own teeth are not advocated by dental universities, as their main field of teaching deals with the repair of teeth and conventional ways of replacing them. …”
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2522“…To adequately address the stagnant acceptance of liberal arts and humanities coursework for future physicians, it is critical to begin with restructuring the larger framework of medical education. …”
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2523por Connolly, Craig T., Cardenas, M. Bayani, Burkart, Greta A., Spencer, Robert G. M., McClelland, James W.“…These substantial fluxes are expected to increase as massive stocks of frozen organic matter in permafrost are liberated in a warming Arctic.…”
Publicado 2020
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2524“…There are also potent pedagogical arguments for the teaching of public health law on a liberal academic curriculum.…”
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2525“…Conservative/restrictive RBC transfusion practices have shown equivalent patient outcomes compared to liberal transfusion practices, and meta-analysis has shown improved in-hospital mortality, reduced cardiac events, re-bleeding, and bacterial infections. …”
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2526por Tan, Zhenda, Fu, Zhongxin, Yang, Jian, Wu, Yang, Cao, Liang, Jiang, Huanfeng, Li, Juan, Zhang, Min“…The catalytic transformation proceeds with the striking features of good substrate and functional group compatibility, high step and atom efficiency, no need for additional reductants, and liberation of H(2)O as the sole by-product, which endows a new platform for direct access to valuable quinazolines. …”
Publicado 2020
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2527“…Cathepsins are proteases with serine, cysteine, or aspartic acid residues as the nucleophiles, which are vital for digestion, coagulation, immune response, adipogenesis, hormone liberation, peptide synthesis, among a litany of other functions. …”
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2528por Goiana-da-Silva, Francisco, Cruz-e-Silva, David, Bartlett, Oliver, Vasconcelos, Joana, Morais Nunes, Alexandre, Ashrafian, Hutan, Miraldo, Marisa, Machado, Maria do Céu, Araújo, Fernando, Darzi, Ara“…In this article we argue that no single ethical theory can account for the complexities inherent in obesity prevention strategy, especially the liberal theories relied upon by opponents of SSBs taxation. …”
Publicado 2020
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2529por Wierson, Wesley A, Welker, Jordan M, Almeida, Maira P, Mann, Carla M, Webster, Dennis A, Torrie, Melanie E, Weiss, Trevor J, Kambakam, Sekhar, Vollbrecht, Macy K, Lan, Merrina, McKeighan, Kenna C, Levey, Jacklyn, Ming, Zhitao, Wehmeier, Alec, Mikelson, Christopher S, Haltom, Jeffrey A, Kwan, Kristen M, Chien, Chi-Bin, Balciunas, Darius, Ekker, Stephen C, Clark, Karl J, Webber, Beau R, Moriarity, Branden S, Solin, Stacy L, Carlson, Daniel F, Dobbs, Drena L, McGrail, Maura, Essner, Jeffrey“…Our vector series, pGTag (plasmids for Gene Tagging), contains reporters flanked by a universal CRISPR sgRNA sequence which enables in vivo liberation of the homology arms. We observed high rates of germline transmission (22–100%) for targeted knock-ins at eight zebrafish loci and efficient integration at safe harbor loci in porcine and human cells. …”
Publicado 2020
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2530por Bergmann, Eirikur“…Perhaps most vitally the book documents a turn away from liberal democracy established in the post-war era, and towards more authoritative illiberal modes of democracy.…”
Publicado 2020
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2531por Xie, Jia, Wang, Shuyue, Ma, Peixiang, Ma, Fei, Li, Jie, Wang, Wei, Lu, Fengping, Xiong, Huan, Gu, Yuang, Zhang, Shuning, Xu, Hongtao, Yang, Guang, Lerner, Richard A.“…Importantly, we used the natural ligand, insulin, to liberate bound molecules. Using this selection method on our relatively small, but highly diverse, nDEL yielded a molecule capable of both binding to and activating the insulin receptor. …”
Publicado 2020
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2532por Carpenter, Randall S., Marbourg, Jessica M., Brennan, Faith H., Mifflin, Katherine A., Hall, Jodie C. E., Jiang, Roselyn R., Mo, Xiaokui M., Karunasiri, Malith, Burke, Matthew H., Dorrance, Adrienne M., Popovich, Phillip G.“…Even though Plerixafor liberates HSPCs and mature immune cells from bone marrow, competitive repopulation assays show that the intrinsic long-term functional capacity of HSPCs is still impaired in SCI mice. …”
Publicado 2020
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2533“…Some zinc sites in viral enzymes may serve as drug targets and may liberate zinc ions, thus leading to changes in intracellular concentration of zinc ions, while increased intracellular zinc may induce biological effects in both the host and the virus. …”
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2534por Jovanovic, Dejana, Tremmel, Peter, Pallan, Pradeep S., Egli, Martin, Richert, Clemens“…Hydrolysis of the phosphoramidate liberates the nucleotide, which can then be phosphorylated to become the pharmacologically active triphosphate. …”
Publicado 2020
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2535por O’Neill, John S., Hoyle, Nathaniel P., Robertson, J. Brian, Edgar, Rachel S., Beale, Andrew D., Peak-Chew, Sew Y., Day, Jason, Costa, Ana S. H., Frezza, Christian, Causton, Helen C.“…Replete stores trigger increased H(+) export which stimulates TORC1 and liberates proteasomes, ribosomes, chaperones and metabolic enzymes from non-membrane bound compartments. …”
Publicado 2020
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2536“…Identified facilitating factors were: (1) the historical role and high status of Swedish midwives; (2) Swedish research and development of medical abortion that enabled an enlarged clinical role for midwives; (3) collaborations between individual clinicians and researchers within the professional associations, and the autonomy of clinical units to implement changes in clinical practice; (4) a historic precedent of changes in abortion policy occurring without prior official or legal sanction; (5) a context of liberal abortion laws, secularity, gender equality, public support for abortion, trust in public institutions; and (6) an increasing global interest in task‐shifting to increase access and reduce costs. …”
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2537por Geng, Jin, Zhang, Yichuan, Gao, Quan, Neumann, Kevin, Dong, Hua, Porter, Hamish, Potter, Mark, Ren, Hua, Argyle, David, Bradley, Mark“…Expanding on this, we show how sulfonyl azide and phenyl azide caged prodrugs of pazopanib and doxorubicin, can be liberated using clinically relevant doses of ionising radiation. …”
Publicado 2021
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2538“…According to moral foundations theory, there are five distinct sources of moral intuition on which political liberals and conservatives differ. The present research program seeks to contextualize this taxonomy within the broader research literature on political ideology as motivated social cognition, including the observation that conservative judgments often serve system-justifying functions. …”
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2539“…It identifies four high-level guidelines that can inform existential transformative game design: (1) ritual theming (i.e., liberation, transformation, and commemoration/celebration); (2) metaphorical approach; (3) contextual mechanisms that promote a readiness for change and processing; and (4) psychological resonance. …”
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2540por Wang, Jinlong, Wang, Qi, Wu, Yiting, Bai, Feitian, Wang, Haiqi, Si, Shurun, Lu, Yongfeng, Li, Xusheng, Wang, Shuangfei“…In this study, a sustainable high yield strategy with respect to other CNF preparations was developed. The cellulose was liberated from plant cell walls and fibrillated to a 7–22 nm thickness in one bath treatment with H(3)PO(4) and H(2)O(2) under mild conditions. …”
Publicado 2020
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