“…Collectively, these results suggest that signal peptidase liberates mature Gc from the Gn/Gc precursor and that this process is essential for viral infectivity and thus constitutes a potential target for antiviral intervention.…”
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“…Our results suggest a prominent biogenesis pathway for bacterial regulatory small RNAs whereby RNase E acts together with the RNA chaperone Hfq to liberate stable 3′ fragments from various precursor RNAs. …”
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“…Protease-dependent liberation of dormant transcription factors triggers diverse cellular responses, such as sterol regulation, Notch signalling and the unfolded protein response. …”
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“…This acceptance involves acknowledging the existence of symptoms, thereby allowing the patient to pursue a meaningful life that is not overly limited by their potential presence. This is not only liberating for the patient but also for the medical professional, who can sometimes feel pressured by patients’ unrealistic expectations to achieve symptom reductions that are not possible. …”
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“…Within the next 24 hours, the patient was liberated from inotropic support, and at 6-month follow-up, her LVEF returned to 55% and she had no heart failure symptoms.…”
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“…C. auris was isolated in 5 patients with nosocomial bloodstream infection, and C. haemulonii was found as a colonizer of leg wounds at a peripheral vascular disease clinic. Liberal use of topical miconazole and close contact among patients were implicated in C. haemulonii transmission. …”
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“…Ectodomain shedding (shedding) is a post-translational modification, which liberates the extracellular domain of membrane proteins through juxtamembrane processing executed mainly by the ADAM (a disintegrin and metalloprotease) family of metalloproteases. …”
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“…This paper examines the translation of human rights norms into discourses on abortion in Northern Ireland, a region where abortion is highly restricted, with extensive contemporary public debate into potential liberalization of abortion law. This paper emanates from research examining political debates on abortion in Northern Ireland and contrasts findings with recent civil society developments, identifying competing narratives of human rights with regard to abortion at the macro- and micro-political level. …”
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“…Older people with long-term diabetes and numerous chronic complications need a more liberal approach to reach specific goals of therapy. …”
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“…Heat from these sills exposed untapped volatile-fertile sediments to contact metamorphism, likely liberating the massive greenhouse gas volumes needed to drive extinction. …”
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“…Multisite phosphorylation of Nup53 critically contributes to its liberation from its partner nucleoporins, including the pore membrane protein NDC1. …”
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“…Oxidative pyrolysis using a tube furnace (Pyrolyser) has been adopted as an industry standard approach for the liberation of tritium (Warwick et al. in Anal Chim Acta 676:93–102, 2010) however pyrolysis of organic-rich materials can be problematic. …”
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“…Paradoxically, the archaeal phylotype that numerically dominates the chimney microbial communities appears ill suited to live in pure hydrothermal fluids without the co-occurrence of organisms that can liberate CO(2). Considering the lack of dissolved inorganic carbon in such systems, the ability to utilize formate may be a key trait for survival in pristine serpentinite-hosted environments.…”
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“…These results suggest that even if there is a heightened liberation of ancient carbon–sourced methane as climate change proceeds, oceanic oxidation and dispersion processes can strongly limit its emission to the atmosphere.…”
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“…Cleavage of high-molecular-weight kininogen liberates bradykinin, the major biologic peptide that promotes the edema. …”
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“…This illuminates the mechanism of a biological switch whereby structured PIP sites are phosphorylated to liberate protein machines from organelle surfaces.…”
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“…During the degradation process, elastases liberate DES from elastin fibers. Blood DES levels consequently reflect the rate of systemic elastinolysis and are increased in COPD. …”
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“…While uncoated indomethacin films were fully released within an hour, polymer coatings showed gradual liberation over several hours to days. Additional insight is gained from evaluating the experimental dissolution data in the framework of diffusive transport. …”
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“…In contrast to historical depictions, Americans generally see God as young, Caucasian, and loving, but perceptions vary by believers’ political ideology and physical appearance. Liberals see God as relatively more feminine, more African American, and more loving than conservatives, who see God as older, more intelligent, and more powerful. …”
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“…A combined study of transient absorption spectroscopy, electrochemical and photoelectrochemical (PEC) measurements reveals that appropriate phase alignment is essential for unidirectional charge transfer, and a junction interface with minimized trap states is crucial to liberate the charge separation potential of the phase junction. …”
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