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2721por Nele, Valeria, Schutt, Carolyn E., Wojciechowski, Jonathan P., Kit-Anan, Worrapong, Doutch, James J., Armstrong, James P. K., Stevens, Molly M.“…Specifically, ultrasound is used as a stimulus to liberate liposomal calcium ions, which then trigger the enzymatic activity of transglutaminase. …”
Publicado 2020
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2722por Jin, Hanyong, Lee, Boeun, Luo, Yongyang, Choi, Yuri, Choi, Eui-Hwan, Jin, Hong, Kim, Kee-Beom, Seo, Sang Beom, Kim, Yong-Hak, Lee, Hyung Ho, Kim, Keun Pil, Lee, Kangseok, Bae, Jeehyeon“…Upon DSB induction, SIRT1 translocates to the nucleus and deacetylates FOXL2 at lysine 124, leading to liberation of XRCC5 and XRCC6 from FOXL2 and formation of the Ku complex. …”
Publicado 2020
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2723por Sundaram, Manu, Ravikumar, Namita, Bansal, Arun, Nallasamy, Karthi, Basavaraja, G. V., Lodha, Rakesh, Gupta, Dhiren, Odena, Marti Pons, Ram, Ashwath, Jayashree, Muralidharan“…Strategies to manage ARDS in COVID-19 include low tidal volume ventilation with liberal sedation-analgesia. At the same time, prevention of transmission of the virus to healthcare workers is extremely important in the intensive care setting dealing with severe cases and requiring procedures generating aerosol. …”
Publicado 2020
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2724por HÄYRY, MATTI“…The application of republicanism to the issue, however, is problematic, and hiding the truth seems to go against the basic tenets of liberal democracy.…”
Publicado 2020
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2725“…After 1990, Kornai and most Western commentators expected that as market integration and private property expand, China would eventually turn into a liberal democracy. Prior to the worldwide fall of communism, Kornai had three primary criteria to determine whether a country was socialist or capitalist; later he amended this with six secondary ones. …”
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2726por Gajamange, Dinesh, Kim, Seung-Hyeon, Choi, Kwang-Sik, Azevedo, Carlos, Park, Kyung-Il“…During this process, a discharge tube formed a porous sponge-like structure that detached before the zoospores were released; thus, this organelle operated as a bung. Liberated zoospores gradually transformed into immature trophozoites, during which detachment of the anterior flagella occurred, but the loss of the posterior flagella was not clearly observed in the present study. …”
Publicado 2020
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2727por Harris, Jeffrey E.“…Data on hospitalization do not support the hypothesis that the observed increase in case incidence was merely the result of liberalization of testing criteria. Parameter estimates from a parsimonious two-group heterogeneous SIR model strongly support the hypothesis that younger persons, having first acquired their infections through increasing social contact with their peers, then transmitted their infections to older, less socially mobile individuals. …”
Publicado 2020
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2728por Suri, Abdul Wahab“…The gradual process of economic liberalization has established “market” as the only legitimate mechanism of the distribution of goods/services as per the efficiency principle. …”
Publicado 2020
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2729por Smondack, P., Gravier, F.-É., Prieur, G., Repel, A., Muir, J.-F., Cuvelier, A., Combret, Y., Medrinal, C., Bonnevie, T.“…PERSPECTIVES: Owing to the emergent character of the COVID-19, actual guidelines will have to be adjusted according to the evolution of the pandemic and the resources of the hospital and liberal sectors, in particular for the long-term follow-up of these patients. …”
Publicado 2020
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2730por Havey, Nicholas Francis“…Conservatives are also more likely than their liberal peers to believe in and push conspiracy theories that the Chinese Communist Party, Bill Gates, and the Deep State are working in conjunction to infect the population and enact a surveillance state. …”
Publicado 2020
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2731por Crocq, Marc-Antoine“…The advances in the scientific knowledge of the ECS place the debate on cannabis liberalization in a new context. …”
Publicado 2020
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2732“…Autophagy, a bulk degradation process within eukaryotic cells, is responsible for cellular turnover and nutrient liberation during starvation. Increasing evidence indicate that this process can be extremely discerning. …”
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2733por Brown, Christopher R, Gupta, Swati, Qin, June, Racie, Timothy, He, Guo, Lentini, Scott, Malone, Ryan, Yu, Mikyung, Matsuda, Shigeo, Shulga-Morskaya, Svetlana, Nair, Anil V, Theile, Christopher S, Schmidt, Karyn, Shahraz, Azar, Goel, Varun, Parmar, Rubina G, Zlatev, Ivan, Schlegel, Mark K, Nair, Jayaprakash K, Jayaraman, Muthusamy, Manoharan, Muthiah, Brown, Dennis, Maier, Martin A, Jadhav, Vasant“…We show that functional siRNA can be liberated from these compartments and loaded into newly generated Argonaute 2 protein complexes weeks after dosing, enabling continuous RNAi activity over time. …”
Publicado 2020
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2734por Meara, Connor H. O’, Coupland, Lucy A., Kordbacheh, Farzaneh, Quah, Benjamin J. C., Chang, Chih-Wei, Simon Davis, David A., Bezos, Anna, Browne, Anna M., Freeman, Craig, Hammill, Dillon J., Chopra, Pradeep, Pipa, Gergely, Madge, Paul D., Gallant, Esther, Segovis, Courtney, Dulhunty, Angela F., Arnolda, Leonard F., Mitchell, Imogen, Khachigian, Levon M., Stephens, Ross W., von Itzstein, Mark, Parish, Christopher R.“…Extracellular histones in neutrophil extracellular traps (NETs) or in chromatin from injured tissues are highly pathological, particularly when liberated by DNases. We report the development of small polyanions (SPAs) (~0.9–1.4 kDa) that interact electrostatically with histones, neutralizing their pathological effects. …”
Publicado 2020
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2735por Kouba, Tomáš, Koval’, Tomáš, Sudzinová, Petra, Pospíšil, Jiří, Brezovská, Barbora, Hnilicová, Jarmila, Šanderová, Hana, Janoušková, Martina, Šiková, Michaela, Halada, Petr, Sýkora, Michal, Barvík, Ivan, Nováček, Jiří, Trundová, Mária, Dušková, Jarmila, Skálová, Tereza, Chon, URee, Murakami, Katsuhiko S., Dohnálek, Jan, Krásný, Libor“…We show that HelD prevents non-specific interactions between RNAP and DNA and dissociates stalled transcription elongation complexes. The liberated RNAP can either stay dormant, sequestered by HelD, or upon HelD release, restart transcription. …”
Publicado 2020
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2736por Macleod, Thomas, Ainscough, Joseph S., Hesse, Christina, Konzok, Sebastian, Braun, Armin, Buhl, Anna-Lena, Wenzel, Joerg, Bowyer, Paul, Terao, Yutaka, Herrick, Sarah, Wittmann, Miriam, Stacey, Martin“…We show that intracellular pro-IL-36γ is upregulated by both fungal and bacterial epithelial microbes; yet, it is only liberated from cells, and subsequently processed to its mature, potent, proinflammatory form, by pathogen-mediated cell damage and pathogen-derived proteases. …”
Publicado 2020
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2737por Gao, Yan-Hong, Zhu, Shi-Cong, Xu, Ya, Gao, Shun-Ji, Zhang, Yu, Huang, Qun-An, Gao, Wen-Hong, Zhu, Jian, Xiang, Hui-Juan, Gao, Xu-Hui“…A total of 63 patients underwent breast nodule resection from October 2018 to December 2019 at the General Hospital of Central Theater Command of the People’s Liberation Army. Clinical data, including indications for minimally invasive biopsy or resection, pathological and surgical results were retrospectively analyzed. …”
Publicado 2020
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2738“…In the steady-state, fragments of peptidoglycan are constitutively liberated from bacterial members of the gut microbiota, cross the gut epithelial barrier and enter the host system. …”
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2739por Tsu, Brian V, Beierschmitt, Christopher, Ryan, Andrew P, Agarwal, Rimjhim, Mitchell, Patrick S, Daugherty, Matthew D“…Mouse NLRP1B can be activated through proteolytic cleavage by the bacterial Lethal Toxin (LeTx) protease, resulting in degradation of the N-terminal domains of NLRP1B and liberation of the bioactive C-terminal domain, which includes the caspase activation and recruitment domain (CARD). …”
Publicado 2021
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2740por Rocha-de-Lossada, Carlos, Marina, Rodriguez-Calvo-de-Mora, Rahul, Rachwani, Davide, Borroni, Álvaro, Santos O., Carlos, Hernando-Ayala“…The opening of the incision seems to avoid globe rupture, acting as a “liberating valve” We report a case of a 92-year-old woman with advanced dry macular degeneration who is referred to our department after suffering a blunt trauma in her left eye with a nightstand. …”
Publicado 2020
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