“…Cyclic GMP-AMP synthase (cGAS) is a predominant and ubiquitously expressed cytosolic onfirmedDNA sensor that activates innate immune responses by producing a second messenger, cyclic GMP-AMP (cGAMP), and the stimulator of interferon genes (STING). cGAS contains a highly disordered N-terminus, which can sense genomic/chromatin DNA, while the C terminal of cGAS binds dsDNA liberated from various sources, including mitochondria, pathogens, and dead cells. …”
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“…Much political conflict in the world revolves around the issue of how much freedom to accord people. Liberal democracies are characterized by, e.g., the rule of law and a strong protection of civil rights, giving individuals a great deal of legally guaranteed freedom to lead their lives as they see fit. …”
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“…To meet the need for direct, phenotypic, and automated malaria parasite detection in field settings, a portable platform to process, image, and analyze whole blood to detect Plasmodium falciparum parasites, is developed. The liberated parasites from lysed red blood cells suspended in a magnetic field are accurately detected using this cellphone‐interfaced, battery‐operated imaging platform. …”
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“…Moreover, as reflected by the experiences of the insured, “autonomy” cannot be analyzed solely in the form transmitted by the liberal tradition; that is, as a clear‐cut entity that can simply be “had”, “exerted”, or “controlled”. …”
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“…Specifically, we report an albumin-binding domain (ABD)-AMP conjugate as a long-circulating conditional AMP therapeutic with a masked activity that can be liberated by proteases in the infected tissue microenvironment. …”
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“…Regardless of how these constructs were measured, believers were less distressed by climate change than non-believers, and with only a few exceptions, these differences disappeared after covarying political orientation (left–right or liberal-conservative). Contrary to those who argue that there is something inherent in religious belief that predisposes people to deny or ignore climate change, the present results suggest that it is the (growing) confluence of faith and conservative political orientation that is responsible for the fact that some people of faith tend to deny climate change or actively oppose efforts to combat it.…”
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“…Moreover, the catalytic effect of pTSA on the foaming agent induced liberation of gases, which are necessary for foam formation during crosslinking. …”
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“…The paper concludes that Indigenous theory is underexplored but is critical to liberation of Indigenous people and has legitimate academic value that scholars need to recognize.…”
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“…By adopting a comparative approach between different regime types, the paper concentrates on Germany and Hungary as case studies for the comparative analysis of the effects the pandemic has had on national governance in the two countries which most strongly represent the growing cleavage between the EU’s liberal Western core and the illiberal Central-Eastern periphery. …”
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“…During growth and division, the bacterial cell wall peptidoglycan (PG) is remodelled, resulting in the liberation of PG muropeptides which are typically reinternalized and recycled. …”
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“…By tuning the pH, the solvent and second ligands, the 1-S/R, 3-S/R underwent polymorphic transitions, resulting in enantioselective liberation of excess enantiomers into solution, until the deposited crystals were slightly enriched with the opposite enantiomer, thereby successfully exhibiting PE. …”
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“…Unfortunately, despite the global trend in recent years tending towards liberalization of abortion as a fundamental right of women in certain circumstances, it is still not guaranteed in all countries of the world in the same way. …”
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“…Therefore, its eco-design should be prioritized by materials researchers to develop devices, where valuable components can be separated and liberated with safe and low energy processes.…”
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“…Co-activation of CXCR4 significantly enhanced phosphorylation by GRK2 through the liberation of Gβγ. These results suggest that ACKR3 ‘senses’ CXCR4 activation through a GRK2-dependent crosstalk mechanism. …”
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“…It has been previously observed that calcination greatly alters the physical properties of the various minerals in pegmatite ores, impacting comminution energy and liberation. Thus, this work investigates the relationships between calcination temperatures and the physical behaviour of hard rock lithium ores. …”
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“…--HTML--><h1 style="text-align: center;"><span style="color:rgb(0, 0, 128)"><span style="font-size:26px"><span style="font-family:liberation sans,sans-serif">The fully-automated human: how is technology augmenting our identities?…”
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“…Palabras clave: Guinea-Bissau, Deforestación, Agricultura, Colonización, Cambio Social life of a landscape along recent history: Marina Padrão Temudo’s case study in Guinea-Bissau SummaryOver the last four decades, Guinea-Bissau peasants faced a liberation and a civil war, major economic, political and social changes and a growing climatic instability. …”
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“…Examining prevalence and treatment practices has become important since reports suggest high risks from liberal use of fluid boluses in African children. …”
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“…This book is a self contained course in electromagnetic theory suitable for senior physics and electrical engineering students as well as graduate students whose past has not prepared them well for books such as Jackson or Landau and Lifschitz. The text is liberally sprinkled with worked examples illustrating the application of the theory to various physical problems. …”
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“…Conceptually arranged in four parts, this book addresses both traditional regulatory frameworks and also liberalized and re-regulated environments. First, an introduction gives a full characterization of power supply including engineering, economic and regulatory viewpoints. …”
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