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  1. 3541
    “…These findings demonstrate two novel TAP-independent routes of antigen processing; one based on highly efficient peptide liberation from the COOH terminus of membrane proteins in the ER, the other on delivery of a cytosolic protein to the ER by an unknown route.…”
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    Two Novel Routes of Transporter Associated with Antigen Processing (TAP)-independent Major Histocompatibility Complex Class I Antigen Processing
  2. 3542
    Publicado 1989
    “…Laser flash photolysis of caged adenosine triphosphate (ATP), in the presence of Ca2+, was used to examine the time course of isometric force development from rigor states in glycerinated tonic (rabbit trachealis) and phasic (guinea-pig ileum and portal vein) smooth muscles. Photolytic liberation of ATP from caged ATP initiated force development, at 20 degrees C, with half-time (t1/2) of 5.4 s in trachealis and 1.2-2.2 s in the phasic muscles. …”
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    Kinetics of contraction initiated by flash photolysis of caged adenosine triphosphate in tonic and phasic smooth muscles
  3. 3543
    “…A closed vessel microwave digestion procedure using a mixture of sulphuric and nitric acids was used to liberate mercury from the adipose matrix. All mercury species were quantitatively oxidized to Hg(II) by a potassium bromate/bromide oxidation, then reduced to Hg(0) vapour by stannous chloride prior to fluorescence detection. …”
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    Development of a method for the determination of ultra-trace level mercury in adipose tissue by cold vapour atomic fluorescence spectrometry
  4. 3544
    “…The fungitoxic compounds thus mainly accumulate as conjugates from which active aglycones may be liberated through the activity of hydrolytic enzymes. …”
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    Systemic resistance and lipoxygenase-related defence response induced in tomato by Pseudomonas putida strain BTP1
  5. 3545
    “…These calculations highlight the benefits for personalization of immunotherapy of human cancer, and in view of the substantial pre-existing antigenic repertoire of tumors, emphasize the enormous potential of therapies that modulate the anti-cancer immune response by liberating it from inhibitory influences.…”
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    Modeling the Repertoire of True Tumor-Specific MHC I Epitopes in a Human Tumor
  6. 3546
    “…Cholesteryl esters were isolated by thin layer chromatography. Fatty acids were liberated by basic hydrolysis and analyzed by HPLC of their p-bromophenacyl derivatives using detection at 254 nm. …”
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    Separation and Determination of Fatty Acids from Lipid Fractions by High-Performance Liquid Chromatography: Cholesterol Esters of Umbilical Cord Arteries
  7. 3547
    “…BACKGROUND: Phospholipase A(2 )liberates free fatty acids and lysophospholipids upon hydrolysis of phospholipids and these products are often associated with detrimental effects such as inflammation and cerebral ischemia. …”
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    A secretory phospholipase A(2)-mediated neuroprotection and anti-apoptosis
  8. 3548
    “…Additionally, the majority of spores liberated from the disks appeared vigorous and developed successfully into new individuals. …”
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    A Strategy for the Proliferation of Ulva prolifera, Main Causative Species of Green Tides, with Formation of Sporangia by Fragmentation
  9. 3549
    por van den Belt, Henk
    Publicado 2009
    “…One particularly interesting finding is that liberal theologians generally deny the religious character of the ‘playing God’ argument—a response which fits in with the curious fact that this argument is used mainly by secular organizations. …”
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    Playing God in Frankenstein’s Footsteps: Synthetic Biology and the Meaning of Life
  10. 3550
    “…Studies of complex disorders in humans indicate that a liberal composite evaluation of genetic linkage is needed to identify underlying quantitative trait loci (QTLs). …”
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    Genome-wide linkage scan for loci associated with epilepsy in Belgian shepherd dogs
  11. 3551
    “…Intriguingly, insulin-induced GLUT4 liberation from its static state appeared to be abolished by either pretreatment with an inhibitor of phosphatidylinositol 3-kinase or overexpression of a dominant-interfering AS160 mutant (AS160/T642A). …”
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    Identification of Three Distinct Functional Sites of Insulin-mediated GLUT4 Trafficking in Adipocytes Using Quantitative Single Molecule Imaging
  12. 3552
    “…RESULTS: Mechanical ventilation induced VILI, displayed by increased pulmonary microvascular leakage and endothelial injury, pulmonary recruitment of neutrophils and Gr-1(high )monocytes, and by liberation of inflammatory cytokines in the lungs. Further, VILI associated systemic inflammation characterized by blood leukocytosis and elevated plasma cytokines was observed. …”
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    Simvastatin attenuates ventilator-induced lung injury in mice
  13. 3553
    “…MBP-GrB fusion protein was cleaved during secretion by an endogenous furin-like proteolytic activity in vivo, liberating enzymatically active GrB without the need of subsequent in vitro processing. …”
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    Maltose-Binding Protein Enhances Secretion of Recombinant Human Granzyme B Accompanied by In Vivo Processing of a Precursor MBP Fusion Protein
  14. 3554
    “…The behavior and toxicity of silver engineered nanoparticles (Ag-ENs) to the mixotrophic freshwater alga Ochromonas danica were examined in the present study to determine whether any other mechanisms are involved in their algal toxicity besides Ag(+) liberation outside the cells. Despite their good dispersability, the Ag-ENs were found to continuously aggregate and dissolve rapidly. …”
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    Intracellular Uptake: A Possible Mechanism for Silver Engineered Nanoparticle Toxicity to a Freshwater Alga Ochromonas danica
  15. 3555
    “…The ureter was clipped before kidney dissection to prevent distal migration of tumor. Following liberation of the kidney, the bladder cuff and intramural ureter were excised by using a Collings knife under cystoscopic guidance. …”
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    Tumor Recurrence Incidence Following Hand-Assisted Laparoscopic Nephroureterectomy
  16. 3556
    “…To address this question, we asked healthy human observers to judge the presence or absence of a noisy sensory signal under economic conditions that favored yes responses (liberal blocks), no responses (conservative blocks), or neither response (neutral blocks). …”
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    Economic Value Biases Uncertain Perceptual Choices in the Parietal and Prefrontal Cortices
  17. 3557
    por Lee, Jay Wook
    Publicado 2010
    “…Early goal-directed therapy has been shown to be effective in patients with severe sepsis or septic shock. On the other hand, liberal fluid administration is associated with adverse outcomes such as prolonged stay in the ICU, higher cost of care, and increased mortality. …”
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    Fluid and Electrolyte Disturbances in Critically Ill Patients
  18. 3558
    por Jarosch, Robert
    Publicado 2011
    “…This means storage of energy in the series elastic Z-filaments and a considerable decrease of the liberated energy of heat and work to (h—w(ap)), where h is the heat energy and w(ap) the stretch energy induced from outside by an apparatus. …”
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    The Different Muscle-Energetics during Shortening and Stretch
  19. 3559
    “…These enzymes are produced by the fungus to liberate monomeric sugars that are used as carbon source. …”
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    Regulation of pentose utilisation by AraR, but not XlnR, differs in Aspergillus nidulans and Aspergillus niger
  20. 3560
    “…However, unfortunately, it is now one of the most common causes of poisoning among agricultural pesticides. It liberates lethal phosphine gas when it comes in contact either with atmospheric moisture or with hydrochloric acid in the stomach. …”
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    Managing aluminum phosphide poisonings
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