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3541por Snyder, Heidi Link, Bačík, Igor, Bennink, Jack R., Kearns, Grainne, Behrens, Timothy W., Bächi, Thomas, Orlowski, Marian, Yewdell, Jonathan W.“…These findings demonstrate two novel TAP-independent routes of antigen processing; one based on highly efficient peptide liberation from the COOH terminus of membrane proteins in the ER, the other on delivery of a cytosolic protein to the ER by an unknown route.…”
Publicado 1997
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3542Publicado 1989“…Laser flash photolysis of caged adenosine triphosphate (ATP), in the presence of Ca2+, was used to examine the time course of isometric force development from rigor states in glycerinated tonic (rabbit trachealis) and phasic (guinea-pig ileum and portal vein) smooth muscles. Photolytic liberation of ATP from caged ATP initiated force development, at 20 degrees C, with half-time (t1/2) of 5.4 s in trachealis and 1.2-2.2 s in the phasic muscles. …”
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3543por Levine, Keith E., Fernando, Reshan A., Lang, M., Essader, Amal, Handy, Robert W., Collins, Bradley J.“…A closed vessel microwave digestion procedure using a mixture of sulphuric and nitric acids was used to liberate mercury from the adipose matrix. All mercury species were quantitatively oxidized to Hg(II) by a potassium bromate/bromide oxidation, then reduced to Hg(0) vapour by stannous chloride prior to fluorescence detection. …”
Publicado 2000
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3544“…The fungitoxic compounds thus mainly accumulate as conjugates from which active aglycones may be liberated through the activity of hydrolytic enzymes. …”
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3545“…These calculations highlight the benefits for personalization of immunotherapy of human cancer, and in view of the substantial pre-existing antigenic repertoire of tumors, emphasize the enormous potential of therapies that modulate the anti-cancer immune response by liberating it from inhibitory influences.…”
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3546“…Cholesteryl esters were isolated by thin layer chromatography. Fatty acids were liberated by basic hydrolysis and analyzed by HPLC of their p-bromophenacyl derivatives using detection at 254 nm. …”
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3547por Armugam, Arunmozhiarasi, Cher, Charmian DN, Lim, KaiYing, Koh, Dawn CI, Howells, David W, Jeyaseelan, Kandiah“…BACKGROUND: Phospholipase A(2 )liberates free fatty acids and lysophospholipids upon hydrolysis of phospholipids and these products are often associated with detrimental effects such as inflammation and cerebral ischemia. …”
Publicado 2009
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3548por Gao, Shan, Chen, Xiaoyuan, Yi, Qianqian, Wang, Guangce, Pan, Guanghua, Lin, Apeng, Peng, Guang“…Additionally, the majority of spores liberated from the disks appeared vigorous and developed successfully into new individuals. …”
Publicado 2010
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3549por van den Belt, Henk“…One particularly interesting finding is that liberal theologians generally deny the religious character of the ‘playing God’ argument—a response which fits in with the curious fact that this argument is used mainly by secular organizations. …”
Publicado 2009
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3550por Oberbauer, Anita M, Belanger, Janelle M, Grossman, Deborah I, Regan, Kelly R, Famula, Thomas R“…Studies of complex disorders in humans indicate that a liberal composite evaluation of genetic linkage is needed to identify underlying quantitative trait loci (QTLs). …”
Publicado 2010
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3551por Fujita, Hideaki, Hatakeyama, Hiroyasu, Watanabe, Tomonobu M., Sato, Masaaki, Higuchi, Hideo, Kanzaki, Makoto“…Intriguingly, insulin-induced GLUT4 liberation from its static state appeared to be abolished by either pretreatment with an inhibitor of phosphatidylinositol 3-kinase or overexpression of a dominant-interfering AS160 mutant (AS160/T642A). …”
Publicado 2010
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3552por Müller, Holger C, Hellwig, Katharina, Rosseau, Simone, Tschernig, Thomas, Schmiedl, Andreas, Gutbier, Birgitt, Schmeck, Bernd, Hippenstiel, Stefan, Peters, Harm, Morawietz, Lars, Suttorp, Norbert, Witzenrath, Martin“…RESULTS: Mechanical ventilation induced VILI, displayed by increased pulmonary microvascular leakage and endothelial injury, pulmonary recruitment of neutrophils and Gr-1(high )monocytes, and by liberation of inflammatory cytokines in the lungs. Further, VILI associated systemic inflammation characterized by blood leukocytosis and elevated plasma cytokines was observed. …”
Publicado 2010
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3553por Dälken, Benjamin, Jabulowsky, Robert A., Oberoi, Pranav, Benhar, Itai, Wels, Winfried S.“…MBP-GrB fusion protein was cleaved during secretion by an endogenous furin-like proteolytic activity in vivo, liberating enzymatically active GrB without the need of subsequent in vitro processing. …”
Publicado 2010
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3554por Miao, Ai-Jun, Luo, Zhiping, Chen, Chi-Shuo, Chin, Wei-Chun, Santschi, Peter H., Quigg, Antonietta“…The behavior and toxicity of silver engineered nanoparticles (Ag-ENs) to the mixotrophic freshwater alga Ochromonas danica were examined in the present study to determine whether any other mechanisms are involved in their algal toxicity besides Ag(+) liberation outside the cells. Despite their good dispersability, the Ag-ENs were found to continuously aggregate and dissolve rapidly. …”
Publicado 2010
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3555“…The ureter was clipped before kidney dissection to prevent distal migration of tumor. Following liberation of the kidney, the bladder cuff and intramural ureter were excised by using a Collings knife under cystoscopic guidance. …”
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3556“…To address this question, we asked healthy human observers to judge the presence or absence of a noisy sensory signal under economic conditions that favored yes responses (liberal blocks), no responses (conservative blocks), or neither response (neutral blocks). …”
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3557por Lee, Jay Wook“…Early goal-directed therapy has been shown to be effective in patients with severe sepsis or septic shock. On the other hand, liberal fluid administration is associated with adverse outcomes such as prolonged stay in the ICU, higher cost of care, and increased mortality. …”
Publicado 2010
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3558por Jarosch, Robert“…This means storage of energy in the series elastic Z-filaments and a considerable decrease of the liberated energy of heat and work to (h—w(ap)), where h is the heat energy and w(ap) the stretch energy induced from outside by an apparatus. …”
Publicado 2011
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3559por Battaglia, Evy, Hansen, Sara Fasmer, Leendertse, Anne, Madrid, Susan, Mulder, Harm, Nikolaev, Igor, de Vries, Ronald P.“…These enzymes are produced by the fungus to liberate monomeric sugars that are used as carbon source. …”
Publicado 2011
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3560“…However, unfortunately, it is now one of the most common causes of poisoning among agricultural pesticides. It liberates lethal phosphine gas when it comes in contact either with atmospheric moisture or with hydrochloric acid in the stomach. …”
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