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  1. 3581
    “…Results from isolated human neutrophils revealed that resveratrol was active extracellularly as well as intracellularly in inhibiting the generation of reactive oxygen species. Liberation of ATP and analysis of apoptosis showed that in the concentration of 100 μM, resveratrol did not change the viability and integrity of isolated neutrophils. …”
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    On the Molecular Pharmacology of Resveratrol on Oxidative Burst Inhibition in Professional Phagocytes
  2. 3582
    por Al-Matary, Abdulrahman, Ali, Jaffar
    Publicado 2014
    “…Islam is considerably liberal concerning abortion, which is dependent on (i) the threat of harm to mothers, (ii) the status of the pregnancy before or after ensoulment (on the 120(th) day of gestation), and (iii) the presence of foetal anomalies that are incompatible with life. …”
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    Controversies and considerations regarding the termination of pregnancy for Foetal Anomalies in Islam
  3. 3583
    “…[Purpose] This study investigated the factors associated with performance-based physical function of older veterans of the People’s Liberation Army Air Force of China (PLAAF). [Subjects and Methods] A cross-sectional survey of 146 older veterans of the PLAAF was carried out. …”
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    Factors Associated with Performance-based Physical Function of Older Veterans of the PLAAF: A Pilot Study
  4. 3584
    “…RESULTS: A restrictive fluid therapy prevents complications seen with liberal, large-volume therapy, even though restrictive fluid loading with crystalloids may not demonstrate large hemodynamic effects in surgical or septic patients. …”
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    Dose and type of crystalloid fluid therapy in adult hospitalized patients
  5. 3585
    por Barar, Jaleh, Omidi, Yadollah
    Publicado 2014
    “…However, to achieve superior pharmacokinetics with maximal efficacy and minimal side effects, these advanced NSs need to become much more intelligent to sense the disease condition and liberate therapeutics on demand.…”
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    Surface modified multifunctional nanomedicines for simultaneous imaging and therapy of cancer
  6. 3586
    “…The simulations suggest that a water molecule, coordinated to the catalytic Ca(2+), donates a proton to Asp121 and then attacks the tetrahedral phosphoacyl intermediate to liberate the diisopropylphosphate product. In contrast, the calculated free energy barrier for hydrolysis of (S)-sarin by the same mechanism is highly unfavorable, primarily because of the instability of the pentavalent phosphoenzyme species. …”
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    Hydrolysis of DFP and the Nerve Agent (S)-Sarin by DFPase Proceeds along Two Different Reaction Pathways: Implications for Engineering Bioscavengers
  7. 3587
    “…Since ethanol was the main fermentation metabolite produced by an engineered and evolved C. thermocellum strain, its ethanol yield on a transgenic switchgrass substrate (gram/gram (g/g) glucan liberated) is the highest produced thus far. This result indicates that the advantages of a modified feedstock can be combined with a modified consolidated bioprocessing microorganism as anticipated.…”
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    Consolidated bioprocessing of transgenic switchgrass by an engineered and evolved Clostridium thermocellum strain
  8. 3588
    por Lun, Aaron T.L., Smyth, Gordon K.
    Publicado 2014
    “…Misinterpreting the former as the latter can result in unexpected liberalness. Here, several solutions are presented to maintain error control for these de novo counting strategies. …”
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    De novo detection of differentially bound regions for ChIP-seq data using peaks and windows: controlling error rates correctly
  9. 3589
    “…After continued budesonide inhalation, he was successfully liberated from the ventilator. CONCLUSIONS: Life-threatening airway obstruction by granulomas developed in a translaryngeally intubated paediatric patient. …”
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    Complete bronchial obstruction by granuloma in a paediatric patient with translaryngeal endotracheal tube: a case report
  10. 3590
    “…In the case of inflammatory disease or trauma where the liberation and exposure to LPS will be increased, the expansion of NSPCs could be a first step towards regeneration of the ENS. …”
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    Maintenance of the enteric stem cell niche by bacterial lipopolysaccharides? Evidence and perspectives
  11. 3591
    “…However, PbICP-negative sporozoites liberated from oocysts exhibited defective motility and invaded mosquito salivary glands in low numbers. …”
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    A Cysteine Protease Inhibitor of Plasmodium berghei Is Essential for Exo-erythrocytic Development
  12. 3592
    “…Signal detection theory analysis revealed a more liberal acceptance bias in those with high dream awareness, consistent with the notion of overlap in the perception of dreams, imagination and reality. …”
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    Dreams, reality and memory: confabulations in lucid dreamers implicate reality-monitoring dysfunction in dream consciousness
  13. 3593
    “…Further mechanistic studies reveal that GRP78 facilitates the extracellular release of APC, thereby rendering the liberation of β-catenin from APC. Furthermore, GRP78 acts through both hindering E-cadherin expression and impairing the interaction of E-cadherin with β-catenin to indirectly and directly influence E-cadherin-β-catenin complex stability. …”
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    GRP78 enhances the glutamine metabolism to support cell survival from glucose deficiency by modulating the β-catenin signaling
  14. 3594
    “…Here we present the genomic background of type strain NRRL Y-12632 and its transcriptomic response to 5-hydroxymethyl-2-furaldehyde (HMF), a commonly encountered toxic compound liberated from lignocellulosic-biomass pretreatment, in dissecting the genomic mechanisms of yeast tolerance. …”
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    Genomic and transcriptome analyses reveal that MAPK- and phosphatidylinositol-signaling pathways mediate tolerance to 5-hydroxymethyl-2-furaldehyde for industrial yeast Saccharomyces cerevisiae
  15. 3595
    por Kang, Hyery, Koh, Dong-Yeun, Lee, Huen
    Publicado 2014
    “…As a potential approach, this paper presents air-driven NGH recovery from permeable marine sediments induced by simultaneous mechanisms for methane liberation (NGH decomposition) and CH(4)-air or CH(4)-CO(2)/air replacement. …”
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    Nondestructive natural gas hydrate recovery driven by air and carbon dioxide
  16. 3596
    “…Analysis revealed that this function is mediated by Bcl-2 family proteins: Cytoplasmic p53 binds Bcl-w, liberating Bax, which then binds ND5, a subunit of respiratory complex-I, thereby suppressing complex-I activity and thus ROS production. …”
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    Nuclear and cytoplasmic p53 suppress cell invasion by inhibiting respiratory Complex-I activity via Bcl-2 family proteins
  17. 3597
    por Parker, Simon, Afsharpad, Arash
    Publicado 2014
    “…Trauma patients with reduced cognitive function should undergo full ATLS assessment, and a prospective trial is required to see if age should be incorporated as a criteria for trauma team activation. More liberal use of advanced imaging such as a full body CT-scan may be beneficial.…”
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    Ground-Level Geriatric Falls: A Not-So-Minor Mechanism of Injury
  18. 3598
    “…Genome analysis also reveals the presence of two additional hydrogenases, an uptake hydrogenase that liberates the electrons in H(2) in support of cell growth, and a regulatory hydrogenase that senses H(2) and relays the signal to a two-component system that ultimately controls synthesis of the uptake hydrogenase. …”
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    Genome Annotation Provides Insight into Carbon Monoxide and Hydrogen Metabolism in Rubrivivax gelatinosus
  19. 3599
    “…Here, we present methodology that permits identification of GPI-APs liberated directly from the surface of intact mammalian cells through exploitation of their appended glycans to enrich for these proteins ahead of LC-MS/MS analyses. …”
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    Proteomic identification of mammalian cell surface derived glycosylphosphatidylinositol-anchored proteins through selective glycan enrichment
  20. 3600
    “…We also show that ER stress combined with inflammation synergistically upregulated the expression of the iron carrier protein NGAL and the stress-inducible heme degrading enzyme heme oxygenase-1 (HO-1) leading to iron liberation. This is the first report to show that inflammation and ER stress downregulate the expression of BDH2 in human THP-1 macrophages.…”
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    Inflammation and ER Stress Downregulate BDH2 Expression and Dysregulate Intracellular Iron in Macrophages
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