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701por Montaguti, Elena, Schürmann, Jan, Wetterauer, Charlotte, Picozzi, Mario, Reiter-Theil, Stella“…Results: Twenty-four out of 100 EC cases addressed coercion in relation to a clinically relevant question, such as compulsory treatment (70.8%), involuntary committal (50%), or restricting liberty (16.6%). Only 58.3% of EC requests mentioned coercion as an ethical issue prior to the meeting. …”
Publicado 2019
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702por Castro, Mario, Rabe, Klaus F., Corren, Jonathan, Pavord, Ian D., Katelaris, Constance H., Tohda, Yuji, Zhang, Bingzhi, Rice, Megan S., Maroni, Jaman, Rowe, Paul, Pirozzi, Gianluca, Amin, Nikhil, Ruddy, Marcella, Akinlade, Bolanle, Graham, Neil M.H., Teper, Ariel“…BACKGROUND: Dupilumab, a fully human monoclonal antibody, blocks the shared receptor component for interleukin-4 and interleukin-13, key drivers of type 2 inflammation. In the phase 3 LIBERTY ASTHMA QUEST trial (NCT02414854) in patients with uncontrolled, moderate-to-severe asthma, add-on dupilumab 200 mg or 300 mg every 2 weeks reduced exacerbations and improved forced expiratory volume in 1 s (FEV(1)) and quality of life over 52 weeks. …”
Publicado 2020
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703“…Totals of 33 T(0) and 160 T(1) plants were confirmed as positive transgenic plants through herbicide application, PCR detection and LibertyLink(®) strip screening. Based on the segregation ratio and Southern Blot data, T(1) lines No. 3 and No. 7 were selected to generate T(2) plants. …”
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704por Liddell, Kathleen, Ruck Keene, Alexander, Holland, Anthony, Huppert, Julian, Underwood, Benjamin R., Clark, Orna, Barclay, Stephen I.G.“…It is not however an absolute right and trade-offs between autonomy, liberty and health need to be made since COVID-19 is highly infectious and poses serious risks of critical illness and death. …”
Publicado 2021
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705“…These results will be discussed under the ethical dimensions of equity, individual liberty, privacy and confidentiality, proportionality, public protection, provision of care, reciprocity, stewardship and trust.. …”
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706por Mehanna, Mai, Chen, Yiqing E., Gong, Yan, Handberg, Eileen, Roth, Brittney, De Leon, Jessica, Smith, Steven M., Harrell, Jonathan G., Cooper‐DeHoff, Rhonda M.“…Patient’s information was entered into the app and treatment recommendations were returned. Clinicians were at liberty to follow or disregard the app’s recommendations. …”
Publicado 2020
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707por Corren, Jonathan, Katelaris, Constance H., Castro, Mario, Maspero, Jorge F., Ford, Linda B., Halpin, David M.G., Rice, Megan S., Radwan, Amr, Deniz, Yamo, Rowe, Paul J., Teper, Ariel, Djandji, Michel“…BACKGROUND: The phase 3 LIBERTY ASTHMA QUEST study (ClinicalTrials.gov: NCT02414854) in patients with uncontrolled, moderate-to-severe asthma has demonstrated the efficacy and safety of dupilumab 200 and 300 mg every 2 weeks versus placebo. …”
Publicado 2021
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708“…Since it overrides some fundamental rights of patients (notably their liberty of movement and decision-making), adequate use of coercion requires legal and ethical justifications. …”
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709“…Policy scholars argue that such controversies represent fundamental frame conflicts, which arise from incommensurable worldviews, such as contested notions of “liberty” versus “equity”. This article investigates frames people constructed to make sense of coronavirus and how this affected social behavior in 2020. …”
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710“…For the detention and the associated deprivation of their liberty to be lawful, it is necessary that the clinical situation meets certain criteria as outlined in the Mental Health Act. …”
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711por Vinay, Kumar, Neelam, Malik, J.S., Sachdeva, Aman, Kumar, Mukesh, Kumar, Hement, Rathee, Manjeet“…BACKGROUND: The United Nations defines violence against women as “any act of gender-based violence that results in, or is likely to result in, physical, sexual or mental harm or suffering to women, including threats of such acts, coercion or arbitrary deprivation of liberty, whether occurring in public or in private life”.[1] Violence can take many forms, including physical, sexual or emotional and varies in its severity. …”
Publicado 2022
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712“…He strongly believed that his liberty to take decisions about his life is being unfairly taken away by the NHS and accused professionals of trying to protect themselves. …”
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713por Ortega-Garcia, Sofia, Perle, Christopher R., Whitney, Nicholas M., Rodriguez-Sanchez, Ruben, O’Sullivan, John, Koch, Stephanie Snyder“…This study applies existing knowledge of FAD-associated dolphinfish diving behavior to identify periods of potential association with floating objects in a remote telemetry dataset of 23 fish with a total of 678 days at liberty spanning two distinct regions within the Eastern Pacific Ocean. …”
Publicado 2022
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714por Revueltas, José“…The central idea is that literature is not separated from social life, the liberty of that one depends on the free life of the latter. …”
Publicado 2021
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715por Papi, Alberto, Corren, Jonathan, Castro, Mario, Domingo, Christian, Rogers, Linda, Chapman, Kenneth R., Jackson, Daniel J., Daizadeh, Nadia, Pandit‐Abid, Nami, Gall, Rebecca, Jacob‐Nara, Juby A., Rowe, Paul J., Deniz, Yamo, Ortiz, Benjamin“…This analysis examined the effect of dupilumab on forced expiratory volume in 1 s (FEV(1)) in patients with moderate‐to‐severe asthma and elevated type 2 biomarkers from phase 3 LIBERTY ASTHMA QUEST (NCT02414854). METHODS: Changes from baseline in pre‐ and post‐bronchodilator (BD) FEV(1) and 5‐item Asthma Control Questionnaire (ACQ‐5) scores were assessed in patients with elevated type 2 biomarkers at baseline (type 2–150/25: eosinophils ≥150 cells/μl and/or fractional exhaled nitric oxide [FeNO] ≥25 ppb; type 2–300/25: eosinophils ≥300 cells/μl and/or FeNO ≥25 ppb), stratified as exacerbators (≥1 severe exacerbation during the study) or non‐exacerbators. …”
Publicado 2022
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716por Yosipovitch, Gil, Mollanazar, Nicholas, Ständer, Sonja, Kwatra, Shawn G., Kim, Brian S., Laws, Elizabeth, Mannent, Leda P., Amin, Nikhil, Akinlade, Bolanle, Staudinger, Heribert W., Patel, Naimish, Yancopoulos, George D., Weinreich, David M., Wang, Sheldon, Shi, Genming, Bansal, Ashish, O’Malley, John T.“…Prurigo nodularis (PN) is a chronic inflammatory skin disease with intensely pruritic nodules. The LIBERTY-PN PRIME and PRIME2 phase 3 trials enrolled adults with PN with ≥20 nodules and severe itch uncontrolled with topical therapies. …”
Publicado 2023
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717Publicado 2023“…People in vulnerable situations such as people in contact with the justice system and people living in prison (PLP) are characterized by exclusionary processes such as stigma and discrimination; restrictions on basic freedoms or rights (e.g., voting, privacy, and liberty); or barriers to accessing public services (e.g., health care). …”
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718“…National laws of European countries allow persons with mental health problems to be deprived of their liberty and undergo involuntary treatment, namely treatment without a patient’s informed consent, in certain circumstances. …”
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719“…Barriers to adopting and maintaining healthy eating and physical activity habits and abstaining from tobacco included normative beliefs around masculinity and individual liberty, the limited social universe of small towns, winter weather, time constraints, and preferences for unhealthy foods. …”
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720por Hameed, Jessica M., McCaffrey, Ramona L., McCoy, Andrea, Brannock, Tracy, Martin, Gregory J., Scouten, William T., Brooks, Krista, Putnam, Shannon D., Riddle, Mark S.“…Based on the epidemiological curve, country of exercise and liberty appeared to be temporally associated with increased risk. …”
Publicado 2016
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