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721por Li, Shuxuan, Cong, Yahui, Liu, Yaping, Wang, Tingting, Shuai, Qin, Chen, Nana, Gai, Junyi, Li, Yan“…Finally, GUS histochemical staining, PCR, herbicide (glufosinate) painting, and QuickStix Kit for Liberty Link (bar) were used to verify the positive transgenic plants, and absolute quantification PCR confirmed the exogenous gene existed as one to three copies in the soybean genome. …”
Publicado 2017
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722“…Inadequate medical and drug supplies as well as non-availability of adolescent friendly health services at the nearest health facility did not only affect social justice and beneficence ethics principles but also threatened juveniles’ privacy, liberty and confidentiality as well as autonomy with regard to health service utilisation. …”
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723por Möhlmann, Tim W. R., Wennergren, Uno, Tälle, Malin, Favia, Guido, Damiani, Claudia, Bracchetti, Luca, Koenraadt, Constantianus J. M.“…METHODS: Mosquitoes were trapped using Biogents Sentinel (BGS), and Mosquito Magnet Liberty Plus (MMLP) traps at a total of 27 locations in Sweden, the Netherlands and Italy, comprising farm, peri-urban and wetland habitats. …”
Publicado 2017
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724por Goldstein, Cory E., Weijer, Charles, Brehaut, Jamie C., Fergusson, Dean A., Grimshaw, Jeremy M., Horn, Austin R., Taljaard, Monica“…But the function of oversight should be understood broadly as protecting the liberty and welfare interest of participants and promoting public trust in research. …”
Publicado 2018
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725por Bankar, Shweta, Collumbien, Martine, Das, Madhumita, Verma, Ravi K., Cislaghi, Beniamino, Heise, Lori“…In India, restrictions on girls’ liberty to move freely in public spaces contribute to school dropout and early marriage, and negatively affect girls’ health and wellbeing, from adolescence into adulthood. …”
Publicado 2018
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726“…Balancing the risks and benefits of treatment, dignity, autonomy, liberty, mental and physical health can be challenging, particularly when imposing interventions with potentially life threatening adverse events, such as clozapine. …”
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727por Silverberg, J.I., Simpson, E.L., Ardeleanu, M., Thaçi, D., Barbarot, S., Bagel, J., Chen, Z., Eckert, L., Chao, J., Korotzer, A., Rizova, E., Rossi, A.B., Lu, Y., Graham, N.M.H., Hultsch, T., Pirozzi, G., Akinlade, B.“…OBJECTIVES: To evaluate the treatment effect of dupilumab in patients with IGA > 1 at the end of treatment, using other validated outcome measures for AD signs, symptoms and quality of life. METHODS: LIBERTY AD SOLO 1 and 2 were two 16‐week, randomized, double‐blind trials enrolling adult patients with moderate‐to‐severe AD (IGA ≥ 3) inadequately controlled with topical treatment. …”
Publicado 2019
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728por Giannopoulos, Stefanos, Secemsky, Eric A., Mustapha, Jihad A., Adams, George, Beasley, Robert E., Pliagas, George, Armstrong, Ehrin J.“…Materials and Methods: The database from the LIBERTY study (ClinicalTrials.gov identifier NCT01855412) was interrogated to identify 503 PAD patients treated with any commercially available endovascular devices and adjunctive OA for 617 femoropopliteal and/or infrapopliteal lesions. …”
Publicado 2020
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729por Pavord, Ian D, Siddiqui, Salman, Papi, Alberto, Corren, Jonathan, Sher, Lawrence D, Bardin, Philip, Langton, David, Park, Hae-Sim, Rice, Megan S, Deniz, Yamo, Rowe, Paul, Staudinger, Heribert W, Patel, Naimish, Ruddy, Marcella, Graham, Neil M H, Teper, Ariel“…PURPOSE: The Phase 3 LIBERTY ASTHMA QUEST study in patients aged ≥12 years with uncontrolled, moderate-to-severe asthma demonstrated the efficacy and safety of dupilumab 200 mg and 300 mg every 2 weeks (q2w) vs matched placebo in the overall population. …”
Publicado 2020
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730por Bourdin, Arnaud, Papi, Alberto A., Corren, Jonathan, Virchow, J. Christian, Rice, Megan S., Deniz, Yamo, Djandji, Michel, Rowe, Paul, Pavord, Ian D.“…In phase 2b (NCT01854047) and phase 3 LIBERTY ASTHMA QUEST (NCT02414854), add‐on dupilumab 200/300 mg every 2 weeks (q2w) reduced severe exacerbations, improved prebronchodilator (pre‐BD) forced expiratory volume in 1 second (FEV(1)) and quality of life measures, and it was generally well tolerated in patients with uncontrolled, persistent (phase 2b), or moderate‐to‐severe (phase 3) asthma. …”
Publicado 2020
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731“…METHODS: A total of 119 patients were recruited from the Chinese People’s Liberty Army General Hospital (Beijing, China). Among them, 20 patients were assessed for a whole-night sleep study by a smartwatch and PSG simultaneously, as well as 82 cases by a smartwatch and HSAT simultaneously. …”
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732por Mora, Marion, Rincon, Giovanna, Bourrelly, Michel, Maradan, Gwenaëlle, Freire Maresca, Anaenza, Michard, Florence, Rouveix, Elisabeth, Pannetier, Julie, Leriche, Diane, Alain, Tristan, Yazdanpanah, Yazdan, Michels, David, Spire, Bruno“…ETHICS AND DISSEMINATION: ANRS Trans&HIV was approved by Inserm’s Ethical Evaluation Committee (no 20-694 on 12 May 2020) and is registered with the National Commission on Informatics and Liberty under number 2518030720. Potential participants are informed about the study through an information note provided by their attending HIV physician. …”
Publicado 2021
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733por Lagdon, Susan, Jordan, Julie-Ann, Devine, Paula, Tully, Mark A., Armour, Cherie, Shannon, Ciaran“…Coercive control is characterised by negative behaviours which intimidate, threaten, and humiliate a person or restrict a person’s liberty. In addition to being a known risk factor for experiencing other forms of violence, research has linked coercive control to symptoms of psychological distress and suicidality. …”
Publicado 2022
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734por Han, Joseph K., Bachert, Claus, Lee, Stella E., Hopkins, Claire, Heffler, Enrico, Hellings, Peter W., Peters, Anju T., Kamat, Siddhesh, Whalley, Diane, Qin, Shanshan, Nelson, Lauren, Siddiqui, Shahid, Khan, Asif H., Li, Yongtao, Mannent, Leda P., Guillemin, Isabelle, Chuang, Chien‐Chia“…We estimated anchor‐based thresholds for clinically meaningful change in objective and patient‐reported outcomes in patients with CRSwNP using data from LIBERTY NP SINUS‐24 and SINUS‐52 trials (NCT02912468; NCT02898454). …”
Publicado 2021
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735“…RESULTS: Four key descriptive patterns were identified: labelling and limits to tolerance, pushing prescription as a solution, coverups and avoiding consent, and family’s fight for liberty. Triangulation across the data and academic literature supports the findings. …”
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736por Siegfried, Elaine C., Simpson, Eric L., Cork, Michael J., Arkwright, Peter D., Wine Lee, Lara, Chen, Zhen, Prescilla, Randy, Bansal, Ashish, Levit, Noah A., Rodríguez Marco, Ainara“…This analysis assessed the effect of dupilumab on the extent and severity of AD across various signs (erythema, edema/papulation, excoriation, lichenification) in different anatomical regions (head and neck, trunk, upper extremities, lower extremities) in patients aged 6 months to 5 years. METHODS: In LIBERTY AD PRESCHOOL, a double-blind, placebo-controlled, phase III clinical trial, children aged 6 months to 5 years with moderate-to-severe AD were randomized 1:1 to subcutaneous dupilumab or placebo with concomitant low-potency topical corticosteroids (TCS) every 4 weeks for 16 weeks. …”
Publicado 2023
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737por Siegfried, Elaine C., Cork, Michael J., Katoh, Norito, Zhang, Haixin, Chuang, Chien-Chia, Thomas, Ryan B., Rossi, Ana B., Cyr, Sonya L., Zhang, Annie“…METHODS: R668-AD-1652 LIBERTY AD PEDS was a randomized, double-blinded, placebo-controlled, parallel-group, phase III clinical trial of dupilumab with concomitant topical corticosteroids (TCS) in children aged 6–11 years with severe AD. …”
Publicado 2023
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738por Meisingset, Ingebrigt, Woodhouse, Astrid, Stensdotter, Ann- Katrin, Stavdahl, Øyvind, Lorås, Håvard, Gismervik, Sigmund, Andresen, Hege, Austreim, Kristian, Vasseljen, Ottar“…Neck flexibility, proprioception, head steadiness, trajectory movement control, and postural sway were assessed using a 3D motion tracking system (Liberty). The different constructs of neck motion and motor control were based on tests used in previous studies. …”
Publicado 2015
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739por Mboera, Leonard E. G., Mweya, Clement N., Rumisha, Susan F., Tungu, Patrick K., Stanley, Grades, Makange, Mariam R., Misinzo, Gerald, De Nardo, Pasquale, Vairo, Francesco, Oriyo, Ndekya M.“…Adult mosquitoes were collected using carbon dioxide-propane powered Mosquito Magnet Liberty Plus traps. In each household compound, water-holding containers were examined for mosquito larvae and pupae. …”
Publicado 2016
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740por Beck, Lisa A., Thaçi, Diamant, Deleuran, Mette, Blauvelt, Andrew, Bissonnette, Robert, de Bruin-Weller, Marjolein, Hide, Michihiro, Sher, Lawrence, Hussain, Iftikhar, Chen, Zhen, Khokhar, Faisal A., Beazley, Bethany, Ruddy, Marcella, Patel, Naimish, Graham, Neil M. H., Ardeleanu, Marius, Shumel, Brad“…METHODS: This ongoing, multicenter, open-label extension study (LIBERTY AD OLE; NCT01949311) assessed dupilumab treatment in adults previously enrolled in dupilumab trials. …”
Publicado 2020
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