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13621“…Therefore, the combination of an oHSV with “standard-of-care” drugs makes a logical and reasonable approach to improved therapy, and the addition of a targeted oncolytic therapy with “standard-of-care” drugs merits further investigation, both preclinically and in the clinic. …”
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13622“…IMPLICATIONS: Given that women do not have total control over attainment of a wanted pregnancy or even prevention of pregnancy, some amount of fatalism about fertility is a logical and pragmatic response. Both research and clinical practice need to recognize that fatalism and contraceptive use are often not in conflict.…”
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13623“…Generation of substitution matrices is a logical extension of the conceptual framework we attempted to build during the development of this work. …”
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13624por Lan, Chunyan, Huang, Xin, Huang, Qidan, Wang, Yin, Gu, Haifeng, Li, Yong, Liu, Jihong“…For grade 3 disease, patients undergoing adjuvant chemotherapy alone had a favorable outcome with the 5-year progression-free survival rate of 84.4% and the OS rate of 95.5%. CONCLUSION: It is logical to speculate that surgery followed by observation might be sufficient for patients with HIR with grade 1–2 tumor. …”
Publicado 2015
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13625“…CONCLUSION: According to our results, TNE is an easy and well-tolerated procedure, it may be logical to tell the patient that the procedure will be less annoying and irritating than they assume. …”
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13626“…Finally, we recommend rigorous inclusion and exclusion criteria, logical study selection process, and reasonable network geometry to ensure robustness and generalizability of the results of NMAs.…”
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13627por McDougall, Craig A., Welsh, Amy B., Gosselin, Thierry, Anderson, W. Gary, Nelson, Patrick A.“…Historical asymmetric (downstream) gene flow in the vicinity of the generating station was the most logical explanation for the observed genetic structuring. …”
Publicado 2017
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13628“…We propose guidelines for the appropriate management of such patients by clinicians involved in their care, allowing more logical treatment to be aimed at reducing the likelihood of sudden cardiac death.…”
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13629por Large, Matthew Michael, Chung, Daniel Thomas, Davidson, Michael, Weiser, Mark, Ryan, Christopher James“…It is usually assumed that this strong association is not causal but is a result of the combination of the selection of high-risk patients for admission and the imperfect protection from suicide afforded by psychiatric wards. Logically, a third factor, which is causal, might play a role in the association. …”
Publicado 2017
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13630por Stallone, Giovanni, Infante, Barbara, Cormio, Luigi, Macarini, Luca, Grandaliano, Giuseppe“…Immunohistochemistry of the cysts demonstrated a high level of phosphorylation of p70S6 kinase, a downstream mTOR target, and since a target therapy that blocks PI3K/Akt/mTOR pathway has been shown to have a scientific and logical rationale to treat this rare intra-abdominal neoplasia, we started the patient on low dose rapamycin therapy, an mTOR inhibitor. …”
Publicado 2017
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13631por Parker, Amy L., Featherstone, Will E., Penna, Nigel T., Filmer, Mick S., Garthwaite, Matthew C.“…Artificial trihedral corner reflectors (CRs) provide high-intensity and temporally stable reflections in SAR time series imagery, more so than naturally occurring permanent scatterers. Therefore, it is logical to co-locate CRs with cGNSS as ground-based geodetic infrastructure for the integrated monitoring of VLM. …”
Publicado 2017
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13632“…To investigate the regulation of cell fate we developed a logical model of the G1/S checkpoint in DNA damage response that takes into account different levels of damage and contemplates the influence of miR-16 through its positive feedback loop formed with p53 and Wip1. …”
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13633por Goswami, Nandu“…As astronauts in space spend substantial amounts of time carrying out exercise training to counteract the microgravity-induced deconditioning and to counteract orthostatic intolerance on return to Earth, it is logical to suggest some of these interventions for bed-confined older persons. …”
Publicado 2017
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13634por Ma, Hing Keung“…In summary, the proposed developmental principle of altruism and human relationships is logical and robust. It is formulated based on the major developmental and social psychological theories. …”
Publicado 2017
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13635por Kamaruddin, Nur Hasiba, Bakar, Ahmad Ashrif A., Mobarak, Nadhratun Naiim, Zan, Mohd Saiful Dzulkefly, Arsad, Norhana“…The maximum signal-to-noise ratio (SNR) upon detection of Pb(2+) is 1.53, and exceeds the suggested logical criterion of an SNR. The Au/Ag/Au/CS–GO SPR sensor also exhibits excellent repeatability in Pb(2+) due to the strong bond between its functional groups and this cation. …”
Publicado 2017
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13636por Kehl, Tim, Backes, Christina, Kern, Fabian, Fehlmann, Tobias, Ludwig, Nicole, Meese, Eckart, Lenhof, Hans-Peter, Keller, Andreas“…Further, miRNAs are known not only to target genes but also to target significant parts of pathways. A logical line of thoughts is: miRNAs with similar (seed) sequence target similar sets of genes and thus similar sets of pathways. …”
Publicado 2017
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13637por Maleki, Masoud, Yousefi, Mahdi, Bazzaz, Sayyed Mojtaba Mousavi, Tabassi, Sayyed Abolghasem Sajadi, Rakhshandeh, Hasan, Hamedi, Shokouh Sadat, Haghighi, Gholamreza“…Finally, matching, syllogism and logical inference were performed and conclusion was made. …”
Publicado 2017
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13638por Shen, Jiayin, Hu, Yingwen, Putt, Karson S., Singhal, Sunil, Han, Haiyong, Visscher, Daniel W., Murphy, Linda M., Low, Philip S.“…Unfortunately, uptake of such imaging agents can be mediated by both major isoforms of the folate receptor, FR-α and FR-β. Logically, if the FR positive cell population in a tumor mass is dominated by FR-β positive macrophages, patients could be selected for therapy that have few FR-expressing cancer cells. …”
Publicado 2017
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13639Chronic Lymphocytic Leukemia B-Cell Normal Cellular Counterpart: Clues From a Functional Perspective“…We discuss the functional characteristics required for a cell to be logically considered to be the normal counterpart of CLL B-cells.…”
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13640por Ding, Qiong, Tanigawa, Kitora, Kaneko, Jun, Totsuka, Mamoru, Katakura, Yoshinori, Imabayashi, Etsuko, Matsuda, Hiroshi, Hisatsune, Tatsuhiro“…Subjects were assessed at the start and end of the trial using several neuropsychological tests, including the Wechsler Memory Scale-Logical Memory (WMS-LM). We also collected two types of MRI data, arterial spin labeling (ASL) and diffusion tensor imaging (DTI) at the start and end of the trial. …”
Publicado 2018
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