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  1. 13941
    “…We aimed to determine the most logical and practical mortality end-point in clinical trials of critically ill patients. …”
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    Landmark survival as an end-point for trials in critically ill patients – comparison of alternative durations of follow-up: an exploratory analysis
  2. 13942
    “…Starting with a generic pathway made of logical gates, we build a cell-type specific map by constraining it to fit 13 key phopshoprotein signals under 55 experimental conditions. …”
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    Identifying Drug Effects via Pathway Alterations using an Integer Linear Programming Optimization Formulation on Phosphoproteomic Data
  3. 13943
    por Reybrouck, Gerald
    Publicado 2007
    “…However, the successes scored by CEN are ultimately only the logical consequence of the accomplishments already achieved by the “International Colloquium”. …”
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    Milestones in the testing of surface disinfectants: from Robert Koch to CEN TC 216
  4. 13944
    “…Therefore, it has been logically assumed that the enzyme responsible for viral RNA replication process, influenza virus type A RNA polymerase (IAV Pol), is a highly error-prone polymerase which provides the genomic mutations necessary for viral evolution and host adaptation. …”
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    Biochemical Characterization of Enzyme Fidelity of Influenza A Virus RNA Polymerase Complex
  5. 13945
    “…Thorough interrogation of these specific regions is the logical next step, including regional haplotype studies to identify risk haplotypes upon which the underlying critical variants lie. …”
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    Haplotype association analyses in resources of mixed structure using Monte Carlo testing
  6. 13946
    por Niu, Wenquan, Qi, Yue
    Publicado 2011
    “…BACKGROUND: Mounting evidence has suggested that α-adducin and G-protein β3 (GNB3) genes are logical candidates for salt-sensitive hypertension. …”
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    Association of α-Adducin and G-Protein β3 Genetic Polymorphisms with Hypertension: A Meta-Analysis of Chinese Populations
  7. 13947
    “…Direct repair of the pars defect is a logical alternative to fusion as it helps to preserve the motion segment and prevents abnormal stresses at the adjacent levels. …”
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    Direct repair of lumbar spondylolysis by Buck’s technique
  8. 13948
    “…Since pancreatic tumours are highly chemoresistant, a logical step would be to investigate the pharmacodynamic, morphological and biochemical effects of omeprazole on pancreatic cancer cell lines. …”
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    Omeprazole Inhibits Proliferation and Modulates Autophagy in Pancreatic Cancer Cells
  9. 13949
    “…Our mapping produces OWL-DL, a Description Logics based subset of OWL with desirable computational properties for efficiency and correctness. …”
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    Mapping between the OBO and OWL ontology languages
  10. 13950
    “…The HMG-coenzyme A reductase inhibitors (statins) inhibit several pro-inflammatory processes and suppress immune activation, and are a logical therapy to assess for a possible salutary effect on HIV disease progression and outcomes. …”
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    Association between Use of HMG CoA Reductase Inhibitors and Mortality in HIV-Infected Patients
  11. 13951
    “…BACKGROUND: Many biological systems are modeled qualitatively with discrete models, such as probabilistic Boolean networks, logical models, Petri nets, and agent-based models, to gain a better understanding of them. …”
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    ADAM: Analysis of Discrete Models of Biological Systems Using Computer Algebra
  12. 13952
    por Green, Jack
    Publicado 2011
    “…Seventy-seven morphological, remote sensing and return sample features were categorized into five categories ranging from a volcano-tectonic origin only to impact origin only. Scores for the most logical scenario were 69 to eight in favor of lunar volcanism. …”
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    Academic Aspects of Lunar Water Resources and Their Relevance to Lunar Protolife
  13. 13953
    “…PRINCIPAL FINDINGS: Adequate biochemical information regarding human DBH, structural coordinates for peptidylglycine alpha-hydroxylating monooxygenase and computational data from a partial model of rat DBH were used along with logical manual intervention in a novel way to build an in silico model of human DBH. …”
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    Structural Insight of Dopamine β-Hydroxylase, a Drug Target for Complex Traits, and Functional Significance of Exonic Single Nucleotide Polymorphisms
  14. 13954
    “…These were subsequently processed using a novel in-house algorithm based on continuous wavelet transform technology within an infrastructure incorporating weighted averaging and logical decision making processes. The computed oximeter respiratory rates (RR(oxi)) were then compared to an end-tidal CO(2) reference rate ([Formula: see text]). …”
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    Developing an algorithm for pulse oximetry derived respiratory rate (RR(oxi)): a healthy volunteer study
  15. 13955
    “…Recent research however, is indicating a need to increase the accuracy beyond that available from traditional TDR. The most logical pathway then becomes a transition from TDR based measurements to network analyzer measurements of absolute permittivity that will remove the adverse effects that high surface area soils and conductivity impart onto the measurements of apparent permittivity in traditional TDR applications. …”
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    Fringe Capacitance Correction for a Coaxial Soil Cell
  16. 13956
    “…However, the 21-bp deletion was regarded as a potentially logical, albeit undetermined, candidate for CAD in the following systematic review. …”
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    Variants in Exon 11 of MEF2A Gene and Coronary Artery Disease: Evidence from a Case-Control Study, Systematic Review, and Meta-Analysis
  17. 13957
    “…The alternative framework offered a logical algorithm to characterize epidemics; it required minimal but key data. …”
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    HIV Epidemic Appraisals for Assisting in the Design of Effective Prevention Programmes: Shifting the Paradigm Back to Basics
  18. 13958
    “…A pilot study has shown good feasibility of a home-based exercise programme that is delivered to this target group through cooperation between general practitioners and exercise therapists. A logical next step involves evaluation of the effects of the programme. …”
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    Effects of an exercise programme for chronically ill and mobility-restricted elderly with structured support by the general practitioner's practice (HOMEfit) - study protocol of a randomised controlled trial
  19. 13959
    “…CONCLUSIONS: Ceramide accumulation induced by TNF-α or tumor development participates in the mechanism of muscle-cell atrophy, and sphingolipid metabolism is a logical target for pharmacological or nutritional interventions aiming at preserving muscle mass in pathological situations.…”
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    TNF-α- and tumor-induced skeletal muscle atrophy involves sphingolipid metabolism
  20. 13960
    “…We particularly focus on the use of Boolean networks that, like classical epistasis analysis, relies on logical formalisms, and hence can complement classical epistasis analysis and relax its assumptions. …”
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    Dynamic Network-Based Epistasis Analysis: Boolean Examples
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