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  1. 458921
    “…METHODS: This mixed-methods-study will be based on the results from a previous systematic review and conducted in three phases: (I) literature-based key intervention-categories of PCC will be investigated during qualitative interviews with Dementia-Care-Managers (DCMs) and PlwD to identify actually patient-relevant (sub) criteria of PCC; (II) based on findings from phase I, an AHP-survey will be designed and pre-tested for face- and content-validity, and consistency during face-to-face “thinking-aloud”-interviews with PlwD and two expert panels (DCMs and physicians); (III) the developed survey will elicit patient preferences and physicians’ judgements for PCC. …”
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    Elicitation of quantitative, choice-based preferences for Person-Centered Care among People living with Dementia in comparison to physicians’ judgements in Germany: study protocol for the mixed-methods PreDemCare-study
  2. 458922
    “…Therapeutic options include surgery, laser excision, and radiofrequency ablation but all are potentially detrimental and expose to local relapse. Therefore, the management frequently relies on a “watchful waiting” approach. …”
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    Topical sirolimus solution for lingual microcystic lymphatic malformations in children and adults (TOPGUN): study protocol for a multicenter, randomized, assessor-blinded, controlled, stepped-wedge clinical trial
  3. 458923
    “…BACKGROUND: Antimicrobial resistance (AMR) is rising at an alarming rate and complicating the management of infectious diseases including lower respiratory tract infections (LRTI). …”
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    Metagenomic prediction of antimicrobial resistance in critically ill patients with lower respiratory tract infections
  4. 458924
    “…We aimed to assess the expression levels of this lncRNA-miRNA-mRNA in patients with psoriasis to elucidate their possible roles in psoriasis management. METHODS: We investigated the lncRNA-PRINS and its target microRNAs (miRNA124-3p, miRNA203a-5p, miRNA129-5p, miRNA146a-5p, miRNA9-5p) and partner genes (NPM, G1P3) expression levels in the plasma of 120 patients with psoriasis compared to 120 healthy volunteers using quantitative real-time polymerase chain reaction and correlated the results with the patients’ clinicopathological data. …”
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    The lncRNA PRINS-miRNA-mRNA Axis Gene Expression Profile as a Circulating Biomarker Panel in Psoriasis
  5. 458925
    “…Paying attention to the changes of these indicators will help surgeons assess the patient's condition and contact the ICU in advance.These data can be fully understood by the patients' families, reduce the unnecessary use of medical resources, and optimize perioperative management.…”
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    Analysis of related factors of scheduled ICU before primary hip arthroplasty
  6. 458926
    “…Therefore, there is need to improve prediction of high-risk individuals, which is critical for efficient management of patients with NVAF. OBJECTIVE: The objective of our paper is to develop a nomogram for predicting the risk of left atrial appendage thrombus (LAAT) and spontaneous echo contrast (SEC), thereby replacing the risk of stroke in NVAF patients. …”
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    A nomogram to predict left atrial appendage thrombus and spontaneous echo contrast in non-valvular atrial fibrillation patients
  7. 458927
    “…OBJECTIVES: Current guidelines base the management of intraductal papillary mucinous neoplasms (IPMN) on several well-established resection criteria (RC), including cyst size. …”
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    Branch-duct intraductal papillary mucinous neoplasm (IPMN): Are cyst volumetry and other novel imaging features able to improve malignancy prediction compared to well-established resection criteria?
  8. 458928
    “…Our findings suggest a need for improved evidence-based substance use disorder management, and strengthened continuity with primary and mental healthcare. …”
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    Characterizing people with frequent emergency department visits and substance use: a retrospective cohort study of linked administrative data in Ontario, Alberta, and B.C., Canada
  9. 458929
    “…CONCLUSIONS: A low level of stress in relation to diabetes management may be associated with lower HbA1c. The larger impact of diabetes on mental health in younger women/people with shorter diabetes duration should be noted when considering psychosocial intervention/behavior change messaging. …”
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    Distress and Living with Diabetes: Defining Characteristics Through an Online Survey
  10. 458930
    por Bizjak, Mojca, Košnik, Mitja, Dinevski, Dejan, Francis Thomsen, Simon, Fomina, Daria, Borzova, Elena, Kulthanan, Kanokvalai, Meshkova, Raisa, Aarestrup, FernandoM, Melina Ahsan, Dalia, Al-Ahmad, Mona, Altrichter, Sabine, Bauer, Andrea, Brockstädt, Maxi, Costa, Célia, Demir, Semra, Fachini Criado, Roberta, Felipe Ensina, Luis, Gelincik, Asli, Giménez-Arnau, Ana Maria, Gonçalo, Margarida, Gotua, Maia, Grønlund Holm, Jesper, Inomata, Naoko, Kasperska-Zajac, Alicja, Khoshkhui, Maryam, Klyucharova, Aliya, Kocatürk, Emek, Lu, Rongbiao, Makris, Michael, Maltseva, Natalya, Pasali, Maria, Paulino, Marisa, Pesqué, David, Peter, Jonny, Dario Ramón, German, Ritchie, Carla, Oliveira Rodrigues Valle, Solange, Rudenko, Michael, Sikora, Agnieszka, Wagner, Nicola, Xepapadaki, Paraskevi, Xue, Xiaoyang, Zhao, Zuotao, Terhorst-Molawi, Dorothea, Maurer, Marcus
    Publicado 2022
    “…Conclusion: Our findings suggest that ColdA is undertreated and call for changes in ColdU management.…”
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    Adrenaline autoinjector is under-prescribed in typical cold urticaria patients living in tropical climate countries
  11. 458931
    “…BACKGROUND: Septic arthritis (SA) is a dangerous condition that requires emergency treatment. Managed by culture-specific antibiotics, irrigation, and debridement (I&D), some patients require repeat surgical treatment. …”
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    Risk factors for septic arthritis and multiple arthroscopic washouts: minimum 2-year follow-up at a major trauma centre
  12. 458932
    “…BACKGROUND: Precision Medicine offers tailored prevention, diagnosis, treatment and management to patients that considers genomics, lifestyle and environmental factors. …”
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    Investigating acceptability of a training programme in precision medicine for frontline healthcare professionals: a mixed methods study
  13. 458933
    “…RESULTS: Fifty-nine studies were included in the review, the majority of which were from high-income countries, particularly the United States. (1) Reported annual costs of multimorbidity per person ranged from I$800 to I$150,000, depending on disease combination, country, cost ingredients, and other study characteristics. (2) Our results further demonstrated that increased country GDP per capita was associated with higher costs of multimorbidity. (3) Meta-analyses of 15 studies showed that on average, dyads which featured Hypertension were among the least expensive to manage, with the most expensive dyads being Respiratory and Mental Health condition (I$36,840), Diabetes and Heart/vascular condition (I$37,090), and Cancer and Mental Health condition in the first year after cancer diagnosis (I$85,820). (4) Most studies reported only direct medical costs, such as costs of hospitalization, outpatient care, emergency care, and drugs. …”
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    Costs of multimorbidity: a systematic review and meta-analyses
  14. 458934
    “…Empower-Autism is a group-based, manualised, post-diagnostic programme that combines autism psycho-education and psychotherapeutic components based on Acceptance and Commitment Therapy to support caregiver mental health, stress management and adjustment to their child’s diagnosis. …”
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    REACH-ASD: a UK randomised controlled trial of a new post-diagnostic psycho-education and acceptance and commitment therapy programme against treatment-as-usual for improving the mental health and adjustment of caregivers of children recently diagnosed with autism spectrum disorder
  15. 458935
    “…CONCLUSIONS: Public drug shortage registers are vital data sources for proactively maintaining and managing a reliable drug supply. However, our study demonstrates that much work remains to standardize the contents and quality of public register data. …”
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    National and transnational drug shortages: a quantitative descriptive study of public registers in Europe and the USA
  16. 458936
    “…METHODS: We retrospectively abstracted and analysed patient management data of HIV positive FSWs who enrolled in care between January 2018 to December 2020. …”
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    A retrospective cross sectional study assessing factors associated with retention and non-viral suppression among HIV positive FSWs receiving antiretroviral therapy from primary health care facilities in Kampala, Uganda
  17. 458937
    “…Further data are required to define the value of these parameters as therapeutic targets for optimized management of TAVR patients. Trial registration DRKS, DRKS00024479. …”
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    Functional and structural reverse myocardial remodeling following transcatheter aortic valve replacement: a prospective cardiovascular magnetic resonance study
  18. 458938
    “…METHODS: Aggregate data that reported pulmonary tuberculosis (PTB) cases from China Tuberculosis Management Information System (TBIMS) from 2006 to 2020 were used to analyze effect coefficients through the age–period–cohort (APC) model based on intrinsic estimator (IE) method, and converted them into relative risk (RR) to estimate trends. …”
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    Age–period–cohort analysis of pulmonary tuberculosis reported incidence, China, 2006–2020
  19. 458939
    “…BACKGROUND: Acute exacerbation of chronic obstructive pulmonary disease (COPD) is an important event in the process of disease management. Early identification of high-risk groups for readmission and appropriate measures can avoid readmission in some groups, but there is still a lack of specific prediction tools. …”
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    Prediction of 30-day risk of acute exacerbation of readmission in elderly patients with COPD based on support vector machine model
  20. 458940
    “…This service evaluation aims to determine whether adults accessing an online weight management programme via a national campaign are successful in losing weight. …”
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    Weight loss outcomes achieved by adults accessing an online programme offered as part of Public Health England’s ‘Better Health’ campaign
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