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“…The utilization of this experimental model can contribute to the improved management of the adverse responses in humans.…”
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“…Previous literature has described avulsion of all three proximal tendons, avulsion of two tendons with retraction of over 2 cm, and tendon avulsions with failure of non-operative management as indications for operative repair. Most previous studies have utilized post-operative protocols that include some form of brace immobilisation to restrict hip flexion and knee extension and/or a limited weight-bearing period. …”
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“…PG1 serum level corrected by patient age can be used in the management of patients at risk for GC with a high predicted probability of having an OLGIM stage ≥2. …”
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“…BACKGROUND: Bendamustine and rituximab (BR) has been a standard of care for the management of patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL). …”
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“…CONCLUSIONS: Our findings indicate that SALL4 critically contributes to MLL-AF9-induced leukemia, unraveling the underlying transcriptional and epigenetic mechanisms in this disease and suggesting that selectively targeting the SALL4 pathway may be a promising approach for managing human MLL-r leukemia. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13045-017-0531-y) contains supplementary material, which is available to authorized users.…”
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“…BACKGROUND: The study compared rates of hospitalization between treatment groups in patients with nontuberculous mycobacterial lung disease (NTMLD) in a US national managed care claims database. METHODS: Patient (N = 1039) pharmacy claims at year 1 following NTMLD diagnosis were classified into 3 treatment groups including triple combo (macrolide + ethambutol + rifamycin ± other drugs) (G1), other antibiotics used by physicians for NTMLD (G2), and no treatment (G3). …”
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“…These data strongly endorse the need for a large, prospective, multicenter study exploring the use of T2C vs. standard of care in the diagnosis and management of this disorder. DISCLOSURES: P. G. Pappas, T2Candida Panel: Grant Investigator and Scientific Advisor, Grant recipient, Research grant and Research support Merck: Grant Investigator, Grant recipient and Research grant Gilead: Grant Investigator, Grant recipient and Research grant Scynexis: Grant Investigator and Scientific Advisor, Grant recipient and Research grant Cidara: Grant Investigator and Scientific Advisor, Grant recipient and Research grant Astellas: Grant Investigator, Grant recipient and Research grant Viamet: Scientific Advisor, Consulting fee Amplyx: Scientific Advisor, Consulting fee Vical: Scientific Advisor, Consulting fee…”
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“…BACKGROUND: Management of multi-drug-resistant (MDR) HIV-1 remains a challenge. …”
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“…BACKGROUND: Detection and identification of microorganism(s) involved in periprosthetic joint infection (PJI) can inform surgical management and directed antibiotic therapy. Metagenomic shotgun sequencing is a powerful tool with the potential to change how many PJIs are diagnosed as it allows direct detection and identification of pathogens in clinical specimens. …”
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“…These findings represented an important step towards improving HCC diagnosis and management.…”
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“…Mainstay of treatment in 38.5% of patients included both invasive ventilation and vasopressor support along with other supportive care like fluids and antibiotics. 23.5% received only supportive management. Duration of stay for 150 (70.4%) patients was between one to seven days. …”
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“…Search terms were broadly categorized as platforms (eg, email), measurement (eg, survey), function/information use (eg, self-management), health care occupations (eg, nurse), and eHealth/telemedicine (eg, mHealth). …”
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“…BACKGROUND: Atrial fibrillation and atrial flutter may be managed by either a rhythm control strategy or a rate control strategy but the evidence on the clinical effects of these two intervention strategies is unclear. …”
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“…Patient-centered studies explored the utility of Google Glass in supporting patients with motor impairments (n=8), visual impairments (n=5), developmental and psychiatric disorders (n=2), weight management concerns (n=3), allergies (n=1), or other health concerns (n=2). …”
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“…OBJECTIVE: The study aimed at profiling the bioactive constituents of the leaves and stem essential oils (LEO and SEO) of P. pellucida, their in vitro antibacterial and radical scavenging properties as probable lead constituents in the management of oxidative stress and infectious diseases. …”
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“…We investigated long-term VL and resistance in HIV-infected children managed without real-time VL monitoring. METHODS AND FINDINGS: In the ARROW factorial trial, 1,206 children initiating ART in Uganda and Zimbabwe between 15 March 2007 and 18 November 2008, aged a median 6 years old, with median CD4% of 12%, were randomised to monitoring with or without 12-weekly CD4 counts and to receive 2 nucleoside reverse transcriptase inhibitors (2NRTI, mainly abacavir+lamivudine) with a non-nucleoside reverse transcriptase inhibitor (NNRTI) or 3 NRTIs as long-term ART. …”
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“…We studied 6 technology-supported programs—video outpatient consultations, global positioning system tracking for cognitive impairment, pendant alarm services, remote biomarker monitoring for heart failure, care organizing software, and integrated case management via data sharing—using longitudinal ethnography and action research for up to 3 years across more than 20 organizations. …”
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“…Feasibility outcome results were (1) referral rate at approximately 20/month, (2) recruitment rate 61%, and (3) successful delivery of PtDA and study management. Pre-consultation, PtDA patients scored lower on the DCS scale (mean, standard deviation [SD] 27.3 (18.4) compared to usual care, 49.4 (18.6); the between-group difference in means [95% confidence interval (CI)] was − 22.1[− 30.23, − 13.97]. …”
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“…CONCLUSIONS: The successful completion of this trial will provide evidence to demonstrate whether dry needling is effective for the management of mechanical neck pain when used in a combined treatment approach, as is the common clinical practice. …”
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