“…Significantly more patients in levomilnacipran ER achieved MADRS response rate (RR 1.35 [95% CI 1.23, 1.47; P<0.00001]) and MADRS remission rate (RR 1.30 [95% CI 1.06, 1.59; P=0.01]). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: BPT was related to improved effects (AMDs: MADRS -2.58; PHQ-9: − 1.35) at higher costs (AMD: +€ 754). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: This was a post hoc analysis of an 8-week, randomized, double-blind, placebo-controlled, Phase 3 study of vortioxetine (10 mg or 20 mg) in Japanese patients aged 20–75 years with recurrent major depressive disorder and a Montgomery–Åsberg Depression Rating Scale (MADRS) score of at least 26. The key outcomes were the predictive value of early partial improvement (reduction in MADRS total score of ≥20% from baseline to week 2) with vortioxetine for MADRS response (≥50% decrease in score from baseline) and remission (decrease in score to ≤10) at week 8. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CADSS scores did not significantly mediate the reduction in MADRS at day 2 or 28 in TRANSFORM-2 or the time to depression relapse in SUSTAIN-1. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Efficacy evaluated by MADRS increases with higher vortioxetine doses, based on meta-analysis data (Thase ME et al, 2016). …”
Enlace del recurso
Enlace del recurso

“…The estimated half‐maximal effective concentration from the MADRS score, BP, and HR were 0.44, 468, and 7,580 ng/mL, respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…After 12 months of VNS a clear reduction of MADRS Scores (41 % on average) was seen (12-months MADRS Score median 17, mean 18). …”
Enlace del recurso
Enlace del recurso

“…Depression severity and perceived concentration were evaluated with the Montgomery-Åsberg Depression Rating Scale (MADRS) and the Quick Inventory of Depressive Symptoms Self-Report. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…No significant difference in MADRS-S. An AIS (head) of three or higher was associated with lower scores in five domains of RAND-36 and two domains of EQ-5D but not for MADRS-S. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Patients with a baseline score of at least 20 on the Montgomery-Asberg Depression Rating Scale (MADRS) were treated with mirtazapine for 6 weeks (30 mg/day) and clinically assessed by their psychiatrists at weekly intervals through the MADRS and Clinical Global Improvement (CGI) rating scales. …”
Enlace del recurso
Enlace del recurso

“…To measure depression, the Montgomery Åsberg Depression Rating Scale (MADRS) was used. RESULTS: According to the total MADRS score, less than half of the patients were classified as having “no depression” (44%), the majority had “light” or “moderate depression” (55%) and one individual had “severe depression” in the Dercum group. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Vilazodone treatment compared with placebo showed significant improvement on all 10 individual MADRS symptom items at end of treatment (P<0.01). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The SHAPS and the SHAPS-C were positively correlated with one another, with levels of depression severity, as measured by the MADRS, and the IDS-SR total scores, and with specific items of the MADRS and IDS-SR sensitive to measuring hedonic capacity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Response was defined as decrease in MADRS-S by ≥50% between baseline and follow-up. Patients with levels of melatonin in the lowest quartile at bedtime had an increased probability of a high MADRS-S score compared to those with the highest levels of melatonin (odds ratio 1.39, 95% CI 1.15–1.69, p<0.01). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In patients with no symptoms of depression (low MADRS), Quetiapine treatment decreased symptoms of akathisia. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These data were analyzed post-hoc to explore the relationship between cognitive measures, depression symptoms (Montgomery–Åsberg Depression Rating Scale, MADRS), and self-reported psychosocial functioning (Sheehan Disability Scale; SDS). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The risk of depression was associated with higher baseline MADRS score and BDI score. Interestingly, when stratified by IL6 C-174G polymorphism, higher baseline depressive symptom severity measured by MADRS and BDI predicted higher risk of depression in the course of antiviral treatment only in high IL-6 producers—G allele carriers (patients with GG and CG genotypes) (p = 0.004, p = 0.00008, respectively). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…At the endpoint, the responder and remitter rates by MADRS score criteria were approximately 32% and 21%, respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…No significant correlation was observed between changes in magnesium serum levels and MADRS or YMRS. The concentration of Mg(2+) ion in course of the treatment was not associated with somatic comorbidities. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The average root‐mean‐squared error (RMSE) in predicting the MADRS score (scale 0–60) was 4.72 using passive data alone, 4.27 using self‐report measures alone, and 4.30 using both. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso