“…Survival analysis showed strongest prognostic effects in the TP25μm zone at the tumour centre for CD8(,) GZMB and CD68 (all p < 0.001) in the primary cohort and for CD8 (p = 0.072), GZMB (p = 0.035) and CD68 (p = 0.004) in the validation cohort with inferior prognostic effects observed at the tumour invasive margin. In a multivariate survival analysis, joint analysis of GZMB and CD68 was similarly prognostic to CD8 in the primary cohort (p = 0.007 vs. p = 0.002) and superior to CD8 in the validation cohort (p = 0.005 vs. p = 0.142). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Biomarkers were analyzed in a central laboratory following standard procedures. Marginal effects from generalized linear models were calculated and percentage differences (PD) of the multivariable-adjusted means of biomarkers between extreme sex-specific quintiles (Q) of cooking methods consumption were computed ([Q5 − Q1/Q1] × 100). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moench] is an important crop for food security in semiarid and arid regions due to its high tolerance to abiotic and biotic stresses and its good performance in marginal lands with relatively low fertility. To deeply understand the interrelationship among sorghum genotype, environment, sowing dates, and densities in the spring sowing early maturing (SSEM) areas of China, and to provide a basis for specifying scientific and reasonable cultural practices, a two-year field experiment was conducted with six popular varieties at six locations. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: Synergistic sources of social and structural marginalization—from sexuality to hunger, homelessness, and injection drug use—are associated with transactional sex in this predominantly Black, heterosexual-identifying sample of MWUO. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…There was no significant difference between the three groups in body weight, water-electrolyte balance, echocardiographic parameters and RAS expression. TMA groups had marginally increased 24 h TMA urine excretion, whereas serum levels and 24 h TMAO urine excretion were increased up to 24-fold, and significantly increased TMAO levels in the liver, kidneys and heart. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…When intravenously injected, HexaRmAb158-scFv8D3 was actively transported over the BBB into the brain in vivo. Brain uptake was marginally lower than that of RmAb158-scFv8D3, but significantly higher than observed for conventional IgG antibodies. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Surgical excision was carried out twice, but with positive margins, therefore definitive radiotherapy was given. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…MBL was 0.11 (0.01–0.20) mm (p = 0.03) and 0.23 (0.07–0.39) mm (p = 0.005) before and after 1 year of follow-up, respectively, indicating that the marginal bone loss is greater for standard-length implants. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This may also happen when non-inferiority designs have large margins. Among solutions, it should be acknowledged that clinico-pathological features, like T4 in colon cancer, may not be abandoned and replaced by novel strategies in real-life practice. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The 90% confidence interval (CI) for the primary endpoint was within the pre-defined equivalence margin of ±11.7% and the treatment differences (SE) in TEAR responders between the treatment groups was − 2.86 (4.16) with 90% CI − 9.71 to 3.99. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…GSEM models further detected 3 pathways explaining >55% of the total effect of SES on dementia risk (Total effect = −0.160 ± 0.067, p = 0.022), namely SES→LIFESTYLE→DEMENTIA (Indirect effect (IE) = −0.041 ± 0.014, p = 0.004), SES→LIFESTYLE→COGN→DEMENTIA (IE = −0.006 ± 0.001, p < 0.001), SES→COGN→DEMENTIA(IE = −0.040 ± 0.008, p < 0.001), with the last two remaining significant or marginally significant in the uppermost income groups. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…On multivariate analysis of derivation cohort, multiple lesions, microscopically positive margin (mPM) and anal sphincter involvement (ASI) were selected into the nomogram. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Top ranked predictor variables (consistently highest importance: C-reactive protein) were largely identical across models, except creatinine, which exhibited marginal (L1, L2, EN, SVM) or high/non-linear effects (LR, RF) on events. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The inactivation time of heating estimated using LR-RT-qPCR was marginally higher than that determined using TCID(50). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: STESS and EMSE were insufficient in outcome prediction for SE patients in ICU, and EMSE was marginally better than STESS. Systemic illness matters in ICU patients with SE, and SE scores should be modified to achieve better accuracy in this severely ill population. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Recurrence is common in glioblastoma multiforme (GBM) because of the infiltrative, residual cells in the tumor margin. Standard therapy for GBM consists of surgical resection followed by chemotherapy and radiotherapy, but the median survival of GBM patients remains poor (~ 1.5 years). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Patients who underwent a radical transthoracic resection with negative margins within 3 months and histologically confirmed esophageal squamous cell carcinoma (pT3-4N0M0 or pTxN + M0, AJCC 7th) were eligible for this study. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…After the GEEs, we estimated the average marginal effects as the attributable disaster effect. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Perennial C(4) grasses from the genus Miscanthus are widely regarded as leading and promising dedicated bioenergy crops due to their high biomass accumulation on marginal land with low environmental impacts and maintenance requirements over its productive life. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We hypothesized three coverage scenarios by 2030: scenario I - pre-COVID trajectory: 80% VMMC coverage; Scenario II - marginal COVID-19 impact: 60% VMMC coverage, and scenario III - severe COVID-19 impact: 45% VMMC coverage. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso