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46741“…CEs were classified as cost saving (more health benefit at a lower cost), very cost-effective (≤$25,000 per life year gained [LYG] or quality-adjusted life year [QALY]), cost-effective ($25,001 to $50,000 per LYG or QALY), marginally cost-effective ($50,001 to $100,000 per LYG or QALY), or not cost-effective (>$100,000 per LYG or QALY). …”
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46742“…In terms of content of care, while there had been a marginal increase in self care the severity of illness had not changed and the survival of a significant proportion of patients generated the need for repeat visits, which increased by 9% a year. …”
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46743por Fang, Hongyun, Li, Yanping, Du, Songming, Hu, Xiaoqi, Zhang, Qian, Liu, Ailing, Ma, Guansheng“…The level of glucose marginally increased in the AA/AT genotype subjects (4.67 ± 0.40 mmol/L vs. 4.60 ± 0.35 mmol/L, P = 0.08). …”
Publicado 2010
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46744“…RESULTS: CYP2C9 c.1075 A>C polymorphism showed a marginal significant difference between drug resistance and drug-responsive patients for the AC genotype (Odds ratio [OR] = 0.57, 95% confidence interval [CI] = 0.32–1.00; P = 0.05). …”
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46745por Narang, Amol K, Miller, Robert C, Hsu, Charles C, Bhatia, Sumita, Pawlik, Timothy M, Laheru, Dan, Hruban, Ralph H, Zhou, Jessica, Winter, Jordan M, Haddock, Michael G, Donohue, John H, Schulick, Richard D, Wolfgang, Christopher L, Cameron, John L, Herman, Joseph M“…Patients who received adjuvant chemoradiation (n = 66) vs. surgery alone (n = 120) showed a higher rate of T3/T4 stage disease (57.6% vs. 30.8%, P < 0.001), lymph node involvement (72.7% vs. 30.0%, P < 0.001), and close or positive margins (4.6% vs. 0.0%, P = 0.019). Five year survival rates among node negative and node positive patients were 58.7% and 18.4% respectively. …”
Publicado 2011
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46746“…In part 3 low plasma uric acid, not high urinary malonedialdehyde or high ratio malonedialdehyde/uric acid was significantly associated with diminished Ca but not oxalate tolerance, with the first nucleating crystal type being mostly Ca phosphate (hydroxyapatite), in the rest Ca oxalate dihydrate; uricemia correlated marginally positively (p = 0.055) with Ca tolerance of urine, stronger with blood pressure and insulin, and negatively with urinary xanthine, fractional N-Alb-P, volume, sodium. …”
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46747por Dobrindt, Oliver, Hoffmeyer, Birgit, Ruf, Juri, Seidensticker, Max, Steffen, Ingo G, Fischbach, Frank, Zarva, Alina, Wieners, Gero, Ulrich, Gerhard, Lohmann, Christoph H, Amthauer, Holger“…In BS images, a mild and poorly defined focal tracer uptake represented a low-grade lesion, whereas an intense and sharply marginated uptake marked a high-grade SFX. In addition, all injuries were categorized by location as high- or low-risk stress fractures. …”
Publicado 2012
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46748por FOxTROT Collaborative Group“…Preoperative therapy resulted in significant downstaging of TNM5 compared with the postoperative group (p=0·04), including two pathological complete responses, apical node involvement (1% [one of 98] vs 20% [ten of 50], p<0·0001), resection margin involvement (4% [four of 99] vs 20% [ten of 50], p=0·002), and blinded centrally scored tumour regression grading: 31% (29 of 94) vs 2% (one of 46) moderate or greater regression (p=0·0001). …”
Publicado 2012
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46749“…Likewise, students with clinical training were more likely to want to emigrate than pre-clinical students, although the difference was marginally significant (adjusted OR = 1.58, 95% CI = 1.00-2.49). …”
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46750por Arievich, Helen, Overend, Tim, Renard, Didier, Gibbs, Michael, Alagappan, Vijay, Looby, Michael, Banerji, Donald“…The 12.5 μg BID dose produced a marginally higher improvement in trough FEV(1) versus placebo than 50 μg OD, however, the response at 12 hours over placebo was suboptimal (74 mL). …”
Publicado 2012
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46751por Kobeissi, Loulou, Mahfoud, Ziyad, Khoury, Brigitte, El Kak, Fayssal, Ghantous, Zeina, Khawaja, Marwan, Nakkash, Rima, Ramia, Sami, Zurayk, Huda, Araya, Ricardo, Peters, Tim J“…While there was also marginal evidence of a beneficial effect on anxiety, there was no evidence of mediation of the effect on MUVD through measures of common mental disorders. …”
Publicado 2012
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46752“…Overall analysis suggests a marginal association of the 4G/5G polymorphism with diabetic retinopathy (for 4G versus 5G: OR 1.13, 95%CI 1.01 to 1.26; for 4G/4G versus 5G/5G: OR 1.30, 95%CI 1.04 to 1.64; for 4G/4G versus 5G/5G + 4G/5G: OR 1.26, 95%CI 1.05 to 1.52). …”
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46753por Khalili, Mitra, Sadeghizadeh, Majid, Ghorbanian, Kamran, Malekzadeh, Reza, Vasei, Mohammad, Mowla, Seyed Javad“…MATERIALS AND METHODS: A matched based case-control study was conducted that included tumor and matched marginal non-tumor surgical specimens from 34 patients diagnosed with gastric adenocarcinoma. …”
Publicado 2012
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46754“…The lower limits of the 2 CI were above predefined non inferiority margin, which demonstrated the non inferiority of Structum(®) in comparison with Chondrosulf(®). …”
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46755por Okumu, Fredros O, Mbeyela, Edgar, Lingamba, Godfrey, Moore, Jason, Ntamatungiro, Alex J, Kavishe, Deo R, Kenward, Michael G, Turner, Elizabeth, Lorenz, Lena M, Moore, Sarah J“…No treatment reduced entry of the vectors into huts, except for marginal reductions due to PermaNet 2.0® nets and DDT. …”
Publicado 2013
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46756por Kutlubaev, Mansur A., Shenkin, Susan D., Farrall, Andrew J., Duncan, Fiona H., Lewis, Susan J., Greig, Carolyn A., Dennis, Martin S., Wardlaw, Joanna M., MacLullich, Alasdair M.J., Mead, Gillian E.“…Stroke subtype (according to the OCSP classification) was marginally predictive (β = 0.17; p = 0.05) and sex was not statistically significant (β = 0.15; p = 0.08). …”
Publicado 2013
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46757por Roxburgh, C S, Richards, C H, MacDonald, A I, Powell, A G, McGlynn, L M, McMillan, D C, Horgan, P G, Edwards, J, Shiels, P G“…T-cell markers, CD3, CD45RO, CD8 and FOXP3 were scored separately as high/low grade in three areas of the tumour: the invasive margin (IM), tumour stroma and cancer cell nests (CCNs). …”
Publicado 2013
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46758“…The number of cells in methanol control group was significantly lower than cell numbers at 20ppm and 25ppm (p = 0.05), and numbers at 5ppm treatment were lower than at 20 and 25ppm (p = 0.05). Furthermore, a marginally significant difference in the number of MR-1 cells was observed among diphenyl Pt- thiosemicarbazone complex treatment groups (p = 0.077), and an increasing trend in the number of cells was noted from ~5.0 × 10(8) cells (methanol control group) to ~5.8 × 10(8) cells (20ppm). …”
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46759“…Reduction in reachable workspace due to wrist weight was most notable in those subjects with NMD with marginal strength reserve and moderate degree of impairment (Brooke = 2) rather than individuals with mild upper extremity impairment (Brooke = 1) or individuals who were more severely impaired (Brooke =3). …”
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46760por Chapman, Kenneth R, Beeh, Kai-Michael, Beier, Jutta, Bateman, Eric D, D’Urzo, Anthony, Nutbrown, Robert, Henley, Michelle, Chen, Hungta, Overend, Tim, D’Andrea, Peter“…The primary objective was to demonstrate the non-inferiority of glycopyrronium versus blinded tiotropium with respect to trough forced expiratory volume in 1 second (FEV(1)) following 12 weeks of treatment (non-inferiority margin: –50 mL). Secondary objectives were to evaluate glycopyrronium versus tiotropium for other spirometric outcomes, breathlessness (Transition Dyspnea Index; TDI), health status (St George’s Respiratory Questionnaire; SGRQ), daily rescue medication use, COPD exacerbations and COPD symptoms over 12 weeks of treatment. …”
Publicado 2014
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