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46921“…56-year-old male with metastatic papillary thyroid cancer who underwent total thyroidectomy in 8/2014, and I-131 ablation in 9/2014, with post-operative pathology revealing multifocal, bilateral papillary thyroid cancer with extrathyroidal extension with surgical resection margins uninvolved. There were positive lymphovascular spread and multiple central compartments and bilateral neck nodes metastases with extranodal extension. …”
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46922“…CASE: A 23-year-old man with a chief complaint of diffuse abdominal pain was found to have a 2.6 x 2.8 cm smoothly marginated soft tissue mass in the right lower quadrant on abdominal computed tomography. …”
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46923“…CRH was consistent with EAS in 10 patients, but suggested CD in 2 with marginal increases in ACTH (34.5%, 38%) but not cortisol. 7 patients had ACTH-secreting tumor on pathology (5 pulmonary, 1 pancreas, 1 appendix NET), and 5 had occult presumed EAS. …”
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46924“…Histologic type was Papillary carcinoma, cribriform - morular variant. All surgical margins were negative. No angio-lymphatic invasion or extra thyroidal extension was identified. …”
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46925“…Pathology from MCC resection showed no evidence of invasion and clear margins, but he did have microscopic focus on inguinal lymph node biopsy. …”
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46926“…Pathology demonstrated poorly differentiated “pure” large cell neuroendocrine carcinoma (G3), 6 cm in greatest dimension, with invasion of liver, duodenum and stomach, negative liver and gastric/small bowel margins. Lymphovascular invasion (LVI) was present with no perineural invasion (PNI), and 3/15 lymph nodes involved. …”
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46927por Izawa, Masao, Azuma, Yukihiro, Hori, Naohiro, Taniguchi, Fuminori, Harada, Tasuku“…From our DNA methylation and gene expression analysis, 6 genes were selected and classified into 3 categories: estrogen-responsive genes with specific methylation (ESR1 and ESR2) or without any methylation (TGFα and GREB1), and estrogen-unresponsive but upregulated genes depending on specific hypomethylation (GATA6 and CYP19). 4) ChIP-seq and ChIA-PET analysis in silico suggested the presence of ER-specific loci within gene bodies and the up- and downstream in estrogen-responsive genes. 5) ChIP and eRNA expression analysis predicted active enhancer regions both in estrogen-responsive and -unresponsive genes. 6) In response to estrogen, TGFα and GREB1 expressions were upregulated, but ESR1 and ESR2 showed marginal responses.Conclusion: We focused on estrogen-responsive and -unresponsive genes linked to the epigenetic environment of endometriotic lesions, and revealed a facet of gene expression in endometriotic cells.…”
Publicado 2020
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46928por Braz, Délia Oliveira, Oliveira, Renata Santarem, Lopes, Fernanda Sousa Cardoso, Pereira, Lara, Domingues, Alessandra, de Castro, Luiz Claudio Goncalves“…Radiographic skeletal inventory showed under mineralized bones with irregular metaphyseal margins, but no signs of fractures. Calcium and phosphate supplementation doses were increased in attempt to correct the metabolic disturbances, and calcitriol was also started. …”
Publicado 2020
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46929por Jacobs, Corbin, Woldemichael, Kehali, Williamson, Hannah, Abisheva, Zhanerke, Howell, Elizabeth, Abdelgadir, Jihad, Dechant, Cosette, Floyd, Scott, Fecci, Peter, Kirkpatrick, John, Adamson, Justus, Torok, Jordan“…The HF-SRS cohort had significantly larger BSmet PTV (median 1.39cc vs 0.39cc, p=0.021), marginal dose (median 25Gy vs 15Gy, p< 0.001), brainstem V10 (median 1.60cc vs 0.47cc, p< 0.001), brainstem V12 (median 0.78cc vs 0.06cc, p< 0.001), and mean brainstem BED (median 9.27Gy(3) vs 6.55Gy(3), p=0.019). …”
Publicado 2019
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46930por Dunmire, Kara M, Wickersham, Tryon A, Frenzel, Leslie L, Sprayberry, Sarah R, Joiner, Logan C, Hernandez, Lily P, Cassens, Andrew M, Dominguez, Brandon, Paulk, Chad B“…From d 0 to 21, ADFI had a marginally significant improvement (P < 0.10) in pigs fed up to 10 LL in the diet. …”
Publicado 2020
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46931por Fiori Nastro, Federico, Pelle, Martina, Di Michele, Flavia, Talamo, Alessandra, Niolu, Cinzia, Siracusano, Alberto“…Since our Hospital is located in a very peripheral area of Rome, where social disadvantage represents a critical issue, we hypothesized different reasons to explain this data such as lower level of education, marginalization and socioeconomic adversity that might increase difficulties to access to health care services. …”
Publicado 2020
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46932por Kwun Nam Chan, Joe, Chung Man Ng, Mary, Fei Wong, Cheuk, Fung Wo, Sui, Sau Man Wong, Corine, Ming Hui, Lai, Wa Chan, Kit, Ming Lee, Ho, Nam Suen, Yi, Chen, Eric, Chung Chang, Wing“…Patients also showed a lower lose-shift rate (t= 2.21, p=0.03) and punishment-driven learning accuracy rates (t=2.42, p=0.018) than controls. Marginally significant main effect of stimulus pair (F=3.98, p=0.05) was revealed in the test phase, with controls showing a significantly higher preference in Frequent Winner vs Frequent Loser (FWFL) pair than patients (t=-2.25, p=0.028). …”
Publicado 2020
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46933“…Results for each of the four subsearches in Dublin (2015) showed that over 60% of websites promoted nonevidence-based diagnostics. A marginal improvement in scientifically robust information was seen in 2019, but results for “allergy test” and “food intolerance” continued to promote alternative testing 57% (8/14) of the time. …”
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46934por Liang, Donghai, Shi, Liuhua, Zhao, Jingxuan, Liu, Pengfei, Schwartz, Joel, Gao, Song, Sarnat, Jeremy, Liu, Yang, Ebelt, Stefanie, Scovronick, Noah, Chang, Howard H“…We did not observe significant associations between long-term exposures to PM(2.5) or O(3) and COVID-19 death outcomes (p-values>0.05), although per IQR increase in PM(2.5) (3.4 ug/m(3)) was marginally associated with 10.8% (95% CI: −1.1% to 24.1%) increase in COVID-19 mortality rate. …”
Publicado 2020
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46935por Wenne, Roman, Zbawicka, Małgorzata, Bach, Lis, Strelkov, Petr, Gantsevich, Mikhail, Kukliński, Piotr, Kijewski, Tomasz, McDonald, John H., Sundsaasen, Kristil Kindem, Árnyasi, Mariann, Lien, Sigbjørn, Kaasik, Ants, Herkül, Kristjan, Kotta, Jonne“…In addition to natural dissemination at larval phase—enhanced by intentional or accidental introductions and rafting—they can spread through hybridization and introgression with local congeners, which can create mixed populations sustaining in environmental conditions that are marginal for pure taxa. The Mytilus species have a wide distribution in coastal regions of the Northern and Southern Hemisphere. …”
Publicado 2020
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46936“…There is clear evidence for seawater intrusion along this coastal margin. We demonstrate how hydraulic anisotropy will impact on the landward extent of seawater for a given groundwater throughflow. …”
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46937“…In the 85 patients who underwent segmentectomy, the mean margin width was 2.84±0.51 cm, the mean operative duration was 165.6±18.3 minutes, the mean operative hemorrhage was 52.1±20.2 mL, and the mean duration of chest tube drainage was 3.9±1.3 days. …”
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46938por Carr, Sarah, Jia, Yang, Crites, Benjamin, Hamilton, Charles, Burris, Walter, Edwards, J. Lannett, Matthews, James, Bridges, Phillip J.“…ABSTRACT: Soils with marginal to deficient levels of selenium (Se) are widespread in the northwest, northeast, and southeast US. …”
Publicado 2020
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46939por Bolm, Louisa, Zghurskyi, Petro, Lapshyn, Hryhoriy, Petrova, Ekaterina, Zemskov, Sergiy, Vashist, Yogesh K., Deichmann, Steffen, Honselmann, Kim C., Bronsert, Peter, Keck, Tobias, Wellner, Ulrich F.“…As compared to parallel alignment, random orientation of stroma fibers was associated with larger tumor size (median 3.62 cm vs. median 2.87cm, p = 0.037), nodal positive disease (76.0% vs. 54.5%, p = 0.040), higher margin positive resection rates (41.9% vs. 15.2%, p = 0.008) and a trend for higher rates of T3/4 tumors (33.3% vs. 15.2%, p = 0.064). …”
Publicado 2020
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46940por Thorbecke, Willem“…They make a profit on the difference between the interest rate they earn on longer-term assets and the rate they pay of short-term deposits (the net interest margin). Low short-term interest rates and compressed spreads between long- and short-term interest rates may impair bank profitability. …”
Publicado 2020
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