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47001por Satapathy, Swayamjeet, Mittal, Bhagwant Rai, Sood, Ashwani, Das, Chandan Krushna, Mavuduru, Ravimohan Suryanarayan, Goyal, Shikha, Shukla, Jaya, Singh, Shrawan Kumar“…The primary end-point was best prostate-specific antigen response rate (PSA-RR), defined according to Prostate Cancer Clinical Trials Working Group-3 as proportion of patients achieving ≥ 50% decline in PSA from baseline. Non-inferiority margin of − 15% was pre-specified for PSA-RR. RESULTS: Between December 2019 and March 2021, 40 of the 45 patients assessed for eligibility underwent randomization. …”
Publicado 2021
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47002por Bahji, Anees, Bach, Paxton, Danilewitz, Marlon, el‐Guebaly, Nady, Doty, Benjamin, Thompson, Laura, Clarke, Diana E., Ghosh, Sumantra Monty, Crockford, David“…However, individuals with SPMI may experience more difficulties with mandated quarantine or self‐isolation because of their illness(es), stigma, and marginalization. To date, there is a lack of consensus on strategies that could aid such individuals in completing isolation. …”
Publicado 2021
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47003por Lin, Chia-Hsin, Lin, Chien-Yu, Fan, Kang-Hsing, Hung, Sheng-Ping, Chou, Yung-Chih, Liu, Chia-Jen, Chou, Wen-Chi, Chen, Yen-Chao, Huang, Shiang-Fu, Kang, Chung-Jan, Chang, Kai-Ping, Wang, Hung-Ming, Cheng, Ann-Joy, Chang, Joseph Tung-Chieh“…Using decision tree analysis, we classified our patients to have a low, intermediate, or high risk of contralateral failure based on three factors: number of ENEs, margin status, and tumor stage. In conclusion, postoperative unilateral RT did not worsen outcomes in patients with ENE+ BMSCC in this cohort. …”
Publicado 2021
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47004por Cieslikowski, Wojciech A., Haber, Tobias, Krajnak, Slavomir, Anic, Katharina, Hasenburg, Annette, Mager, René, Thüroff, Joachim W., Brenner, Walburgis“…Our results showed that monotherapy with sorafenib was the most efficient in both PCa cell lines. A marginally additive effect of rottlerin was only observed in LNCaP cells treated with sunitinib at a high concentration. …”
Publicado 2021
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47005“…We assessed 5 outcomes: having a primary care provider, having a primary care provider with whom the respondent was comfortable discussing trans health issues, past-year unmet health care need, medical gender affirmation status, and being on a wait-list to access gender-affirming medical care. Average marginal predictions were estimated from multivariable logistic regression models with multiply imputed data. …”
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47006por Skibicki, Hope, Saini, Sundeep, Rogero, Ryan, Nicholson, Kristen, Shakked, Rachel J., Fuchs, Daniel, Winters, Brian S., Raikin, Steven M., Pedowitz, David I., Daniel, Joseph N.“…Patients with a self-reported history of depression (p=.094) or diabetes (p=.097) demonstrated marginal correlation with prolonged narcotic use. CONCLUSION: Our study demonstrated that patients who underwent outpatient surgical fixation of an ankle or tibial plafond fracture were initially overprescribed narcotics by nearly 67%, leaving a significant quantity of pills unused for potential abuse or diversion. 18.7% of originally opioid naïve patients required continued analgesia 90 days after the index procedure, however large variations in consumption rates make it difficult for physicians to predict prolonged narcotic use.…”
Publicado 2019
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47007por Casscells, Nicholas, Dean, Daniel M., Cooper, Paul S., Miller, Stuart D., Guyton, Gregory P.“…In 2016, Cartiva, a cylindrical polyvinyl 1st MTP implant, was approved for use in this condition by the FDA upon the basis of a company-sponsored, nonblinded, randomized controlled trial (MOTION) that reported noninferiority to arthrodesis at a -15% difference of proportions margin using a multipart ad hoc definition of surgical success. …”
Publicado 2020
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47008“…A grading system was also utilized to classify scenarios in which the screw breached the distal cortical wall: Grade 1 was defined as contact between the virtual screw and the cortex, Grade 2 as the screw approaching the outer margin of the cortex, and Grade 3 as the screw penetrating the outer cortex. …”
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47009por Sobouti, Farhad, Aryana, Mehdi, Dadgar, Sepideh, Alizadeh Navaei, Reza, Rakhshan, Vahid“…Abrasion + silane + bonding yields controversial results, being slightly (marginally significantly) better than HF + silane + bonding. …”
Publicado 2022
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47010por Rawlins, Megan E., Limon, Georgina, Adedeji, Adeyinka J., Ijoma, Sandra I., Atai, Rebecca B., Adole, Jolly A., Dogonyaro, Banenat B., Joel, Atuman Y., Beard, Philippa M., Alarcon, Pablo“…Herd-level net financial impact of the disease and its vaccination was assessed using gross margin (GM) and partial budget analyses. These were then used to assess regional financial impact of disease and profitability of a 3-year vaccination programme using a cost-benefit analysis. …”
Publicado 2022
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47011por Blayney, Douglas W., Mohanlal, Ramon, Adamchuk, Hryhoriy, Kirtbaya, Dmitry Valikovich, Chen, Michael, Du, Lihua, Ogenstad, Stephan, Ginn, Greg, Huang, Lan, Zhang, Qingyuan“…RESULTS: Among the 105 patients included in the analysis (65 [6.19%] women; median age, 59 [range, 31-81] years), the primary end point was met within a noninferiority margin of 0.65 days, with a mean difference of 0.52 days (98.52% CI, 0.40-0.65 days). …”
Publicado 2022
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47012por Ward, Ralph, Weeda, Erin R., Bishu, Kinfe G., Axon, R. Neal, Taber, David J., Gebregziabher, Mulugeta“…Statin use was defined as any therapy and subcategorized as high versus low or moderate intensity per the American College of Cardiology/American Heart Association guidelines. Marginal generalized estimating equation-type models for longitudinal data were used to model the association between dual health care utilization status (< 50%, 50%-80%, and > 80% VHA utilization, with the first group serving as the reference group) and statin use after adjusting for measured covariates. …”
Publicado 2020
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47013por Han, Renru, Ding, Li, Yang, Yang, Guo, Yan, Yin, Dandan, Wu, Shi, Zhi, Peiyuan, Zhu, Demei, Liu, Qingmei, Tan, Xiaojuan, Zhu, Yuanju, Zhang, Jay, Li, Li, Hu, Fupin“…Doxycycline (33.4% susceptible), gentamicin (31.3% susceptible), meropenem (30.6%, susceptible), imipenem (30.2% susceptible), ceftazidime (27.8% susceptible), piperacillin-tazobactam (27.2% susceptible), and levofloxacin (27.2% susceptible) showed marginally poor antibacterial activity against tested isolates according to CLSI breakpoints, except for minocycline (73.7% susceptible). …”
Publicado 2022
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47014por Biagiotti, Marco, Bassani, Giulia Alessandra, Chiarini, Anna, Vincoli, Valentina Teodolinda, Dal Prà, Ilaria, Cosentino, Cesare, Alessandrino, Antonio, Taddei, Paola, Freddi, Giuliano“…This allowed to obtain a value of the Margin of Safety of 15, indicating that the amount of FA left on SF mats after electrospinning does not raise concerns for human health.…”
Publicado 2022
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47015por Aldhohrah, Taghrid, Qin, Ge, Liang, Dongliang, Song, Wanxing, Ge, Linhu, Mashrah, Mubarak Ahmed, Wang, Liping“…The outcome variables were buccal tissue thickness (BTT), mid-buccal gingival level (MGL), marginal bone loss (MBL), and pink esthetic scores (PES). …”
Publicado 2022
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47016“…IMPORTANCE: Critics of the federal 340B Drug Pricing Program raised concerns that the program might provide financial incentives for participating hospitals to prescribe more and/or more expensive drugs because the revenue generated from Medicare reimbursement exceeds the purchase price by a substantial margin. Studies showing higher Medicare Part B drug spending at hospitals that are 340B hospitals, which can purchase outpatient drugs from manufacturers at discounted prices, compared with non-340B hospitals were used by the Centers for Medicare & Medicaid Services to justify their 340B payment policy that reduced Medicare payments for drugs in the 340B program in 2018 and thereafter. …”
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47017por Wang, Linwei, Dowdy, David W., Comins, Carly A., Young, Katherine, Mcingana, Mfezi, Mulumba, Ntambue, Mhlophe, Hlengiwe, Chen, Claire, Hausler, Harry, Schwartz, Sheree R., Baral, Stefan, Mishra, Sharmistha“…The following were associated with a reduction in the average marginal HRQoL score: older age (per decade: 0.018 [95% confidence interval (CI): 0.008, 0.027]), drug use (0.022 [0.007, 0.036]), experience of violence (0.024 [0.010, 0.038]) and moderate (vs. no) level of internalized stigma (0.023 [0.004, 0.041]). …”
Publicado 2022
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47018por Zahn, Carmen, Leisner, David, Niederhauser, Mario, Roos, Anna-Lena, Iseli, Tabea, Soldati, Marco“…An examination of verbal communication revealed more game-related communication in the creative mode than in the cooperative mode (P=.01) and the competitive mode (P=.09) with marginally significant effects and strong effect sizes (Cohen f=0.841). …”
Publicado 2022
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47019“…Comparing MA with TM among beneficiaries with disabilities, those in MA had significantly better rates of access to a usual source of care (90.2% vs 84.9%; adjusted propensity-weighted marginal difference [APWMD], 2.9%; 95% CI, 0.2%-5.7%), access to specialist visits (53.2% vs 44.8%; APWMD, 5.5%; 95% CI, 0.6%-10.5%), cholesterol screenings (91.1% vs 86.4%; APWMD, 3.8%; 95% CI, 0.9%-6.7%), influenza vaccinations (61.4% vs 51.5%; APWMD, 10.4%; 95% CI, 5.3%-15.5%), and colon cancer screenings (68.4% vs 54.6%; APWMD, 10.3%; 95% CI, 4.8%-15.8%). …”
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47020“…Measurements (in mm) of the SSS width and deviation of its lateral margin from the midline were obtained along the entire length of the structure at six craniometric points [at mid-distance between Nasion and Bregma (½ N-B); at Bregma (B); in the middle of the Bregma-Lambda segment (½ B-L); at Lambda (L); halfway between Lambda and Inion (½ L-I); and at Inion (I)]. …”
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