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  1. 47461
    “…With a non-inferiority margin of 5%, a two-sided alpha risk of 5%, a beta risk of 20%, and a loss-to-follow-up rate of 10%, the calculated sample size is 1476 included patients, i.e., 738 per group. …”
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    The value of post-operative antibiotic therapy after laparoscopic appendectomy for complicated acute appendicitis: a prospective, randomized, double-blinded, placebo-controlled phase III study (ABAP study)
  2. 47462
    “…Intraobserver concordance metrics included reporting elements of top-line diagnosis, margin status, lymphovascular and/or perineural invasion, pathology stage, and ancillary testing. …”
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    Validation of a digital pathology system including remote review during the COVID-19 pandemic
  3. 47463
    “…Furthermore, 61 (84.7%) had a high grade (G2–G3) with 6 (8.3%) positive surgical margins. The 1- and 5-year OS rates were respectively 73.3% and 59.9%, while the 1- and 5-year DFS rates were respectively 67.3% and 35.1%. …”
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    Radical penectomy, a compromise for life: results from the PECAD study
  4. 47464
    “…In addition to two working ports on the upper and lower margins of the right breast, an inguinal incision and an axillary incision are made. …”
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    The use of the Scar Cosmesis Assessment and rating scale to evaluate the cosmetic outcomes of totally thoracoscopic cardiac surgery
  5. 47465
    “…AR-negative status was significantly associated with tumour necrosis > 50%(p = 0.031), moderate to extensive lymphocytic infiltrate at the tumour margin(p = 0.025) and basal triple negative breast carcinoma(p = 0.016). …”
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    Androgen receptor expression in a Sri Lankan patient cohort with early breast carcinoma
  6. 47466
    “…Adjusting for resident factors marginally reduced this range (42.6 to 155.5 DOT/1000 days). …”
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    Trends, determinants and differences in antibiotic use in 68 residential aged care homes in Australia, 2014–2017: a longitudinal analysis of electronic health record data
  7. 47467
    “…However, racial and ethnic disparities in adolescent HIV infection cannot be attributed to individual-level factors alone and are situated within larger social and structural contexts that marginalize and predispose sexual and gender minority youth of color to HIV. …”
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    Work2Prevent, an Employment Intervention Program as HIV Prevention for Young Men Who Have Sex With Men and Transgender Youth of Color (Phase 3): Protocol for a Single-Arm Community-Based Trial to Assess Feasibility and Acceptability in a Real-World Setting
  8. 47468
    “…CONCLUSIONS: Current pooled results suggest that the addition of NE to non-catecholamine vasopressors was associated with a marginally significant reduction in 28-day mortality. …”
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    Non-catecholamine vasopressors in the treatment of adult patients with septic shock—evidence from meta-analysis and trial sequential analysis of randomized clinical trials
  9. 47469
    “…All patients completed surgery. Resection margins were R0 in 19 patients and R1 in 1 patient. …”
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    Preoperative accelerated radiotherapy combined with chemotherapy in a defined cohort of patients with high risk soft tissue sarcoma: a Scandinavian Sarcoma Group study
  10. 47470
    “…However, for (111)In, (123)I, (124)I, and (90)Y, more than half of all measurements were not accurate within ± 5% range ((111)In, 51%; (123)I, 83%; (124)I, 63%; (90)Y, 61%) and not all were within ± 10% margin ((111)In, 22%; (123)I, 35%; (124)I, 15%; (90)Y, 25%). …”
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    An international multi-center investigation on the accuracy of radionuclide calibrators in nuclear medicine theragnostics
  11. 47471
    “…However, when variance in cognition, psychopathology, social environment, and sociodemographic covariates were accounted for, most forms of SMA were no longer significantly associated with recreational activity engagement (p > .05). Some marginal effects were observed: for every one SD increase in time spent on games and movies over more social forms of media, youth were at lower odds of engaging in recreational activities (adjusted odds ratio = 0·83, 95% CI 0·76–0·89). …”
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    Screen media activity does not displace other recreational activities among 9–10 year-old youth: a cross-sectional ABCD study®
  12. 47472
    “…The main outcome measure was change in maximum keratometry (K(max)) centered on the steepest point (zonal K(max) − 3 mm) with a non-inferiority margin of 1.0 diopter (D). Vision and refraction tests, ophthalmic examinations, and corneal tomography were performed at baseline and at 6, 12, and 24 months after CXL. …”
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    Accelerated and Standard Corneal Cross-Linking Protocols in Patients with Down Syndrome: A Non-inferiority Contralateral Randomized Trial
  13. 47473
    “…RESULTS: Among the 4,396 participants with complete test results, the sensitivity of uRDTs (68.2; 95% CI 60.8 to 74.9) was marginally better than that of cRDTs (61.5; 95% CI 53.9 to 68.6) (p-value = 0.004), while the specificities were similar (uRDT: 99.0 [95% CI 98.6 to 99.2], cRDT: 99.2 [95% CI 98.9 to 99.4], p-value = 0.02). …”
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    Field performance of ultrasensitive and conventional malaria rapid diagnostic tests in southern Mozambique
  14. 47474
    “…The single population proportion formula was applied to estimate the sample size taking into account the proportion of data use 0.69, margin of error 0.05, and the critical value 1.96 at the 95% CI. …”
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    Routine health information system utilization for evidence-based decision making in Amhara national regional state, northwest Ethiopia: a multi-level analysis
  15. 47475
    “…IDeg-100 was confirmed (non-inferiority margin of 0.30%; upper 95% CI at 6 months, 0.09%). …”
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    Comparative Effectiveness of Switching From First-Generation Basal Insulin to Glargine 300 U/ml or Degludec 100 U/ml in Type 1 Diabetes: The RESTORE-1 Study
  16. 47476
    “…GLILD patients presented lower percentage of switched-memory B cells and marginal zone B cells, and a marked increase in the percentage of circulating CD21lo B cells (14.2 vs. 2.9%). …”
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    Granulomatous Lymphocytic Interstitial Lung Disease (GLILD) in Common Variable Immunodeficiency (CVID): A Multicenter Retrospective Study of Patients From Italian PID Referral Centers
  17. 47477
    “…RESULTS: Between T0 and T1, no significant differences in outcomes were observed, except for a marginal increase in gait speed (+ 2.9%). Following the intervention, propulsion symmetry (+ 7.9%) and paretic propulsive impulse had significantly improved (+ 8.1%), whereas non-paretic propulsive impulse remained unchanged. …”
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    Task-specific training for improving propulsion symmetry and gait speed in people in the chronic phase after stroke: a proof-of-concept study
  18. 47478
    “…RESULTS: Eight SNPs were not associated with clinical manifestations of PMN patients (Pc < 0.05). rs3828323 T allele was marginally significantly associated with hypertension (P = 0.008, Pc = 0.064, OR = 1.821). …”
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    The association between variants in PLA2R and HLA-DQA1 and renal outcomes in patients with primary membranous nephropathy in Western China
  19. 47479
    “…Based on primary study adjusted odds ratios, our meta-analysis calculated a 4.06 (95% confidence interval (CI): 3.00–5.48, I(2) 68%, 9 primary studies) times higher odds of commencing tobacco cigarette smoking for teenagers who had ever used e-cigarettes at baseline, though the odds ratio were marginally lower (to 3.71 times odds, 95%CI: 2.83–4. 86, I(2) 35%, 4 primary studies) when only the four high-quality studies were analysed. …”
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    Association between electronic cigarette use and tobacco cigarette smoking initiation in adolescents: a systematic review and meta-analysis
  20. 47480
    “…MAIN OUTCOME MEASURES: The primary outcome was a composite of all cause death, myocardial infarction, and stroke, tested for non-inferiority against a margin of 1.15 for the hazard ratio. The key safety endpoint was Bleeding Academic Research Consortium (BARC) type 3 or type 5 bleeding. …”
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    P2Y12 inhibitor monotherapy or dual antiplatelet therapy after coronary revascularisation: individual patient level meta-analysis of randomised controlled trials
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