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47621por Chiou, Cho-Yen“…There were two sub-centimeter cancer foci, partially encapsulated without capsular or vascular invasion, and surgical margin was clear. It was classified as pT1aNxMx, without clinical evidence of lymph node or distant metastasis. …”
Publicado 2019
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47622por Bikbov, Mukharram M., Kazakbaeva, Gyulli M., Zainullin, Rinat M., Salavatova, Venera F., Gilmanshin, Timur R., Yakupova, Dilya F., Uzianbaeva, Yulia V., Arslangareeva, Inga I., Panda-Jonas, Songhomitra, Mukhamadieva, Svetlana R., Khikmatullin, Renat I., Aminev, Said K., Nuriev, Ildar F., Zaynetdinov, Artur F., Jonas, Jost B.“…Prevalence of moderate anemia (hemoglobin concenttration:110 g/L-80 g/L), detected in 165 individuals (2.8%;95%CI:2.4,3.2), increased with younger age (P = 0.008;odds ratio (OR):0.98;95%CI:0.96,0.99), female gender (P < 0.001;OR:2.52;95%CI:1.47,4.33), higher erythrocyte sedimentation rate (P < 0.001;OR:1.08;95%CI:1.06,1.09), longer blood clotting time (P < 0.001;OR:8.56;95%CI:5.68,12.9), and marginally significantly, with a lower waist-hip circumference ratio (P = 0.058;OR:0.13;95%CI:0.02,1.07). …”
Publicado 2019
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47623por Keulen, Judit KJ, Bruinsma, Aafke, Kortekaas, Joep C, van Dillen, Jeroen, Bossuyt, Patrick MM, Oudijk, Martijn A, Duijnhoven, Ruben G, van Kaam, Anton H, Vandenbussche, Frank PHA, van der Post, Joris AM, Mol, Ben Willem, de Miranda, Esteriek“…The null hypothesis that expectant management is inferior to induction was tested with a non-inferiority margin of 2%. RESULTS: Median gestational age at delivery was 41 weeks+0 days (interquartile range 41 weeks+0 days-41 weeks+1 day) for the induction group and 41 weeks+2 days (41 weeks+0 days-41 weeks+5 days) for the expectant management group. …”
Publicado 2019
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47624“…Multivariable generalized ordered logistic regressions examined the association of social media use with different levels of physical activity and sleep. We estimated marginal effects (MEs) for the main independent variable (social media use frequency) by holding all other variables at their observed values. …”
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47625por Earl, Helena M, Hiller, Louise, Vallier, Anne-Laure, Loi, Shrushma, McAdam, Karen, Hughes-Davies, Luke, Harnett, Adrian N, Ah-See, Mei-Lin, Simcock, Richard, Rea, Daniel, Raj, Sanjay, Woodings, Pamela, Harries, Mark, Howe, Donna, Raynes, Kerry, Higgins, Helen B, Wilcox, Maggie, Plummer, Chris, Mansi, Janine, Gounaris, Ioannis, Mahler–Araujo, Betania, Provenzano, Elena, Chhabra, Anita, Abraham, Jean E, Caldas, Carlos, Hall, Peter S, McCabe, Christopher, Hulme, Claire, Miles, David, Wardley, Andrew M, Cameron, David A, Dunn, Janet A“…The primary endpoint was disease-free survival, analysed by intention to treat, with a non-inferiority margin of 3% for 4-year disease-free survival. Safety was analysed in all patients who received trastuzumab. …”
Publicado 2019
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47626por Chen, Di-Xiang, Hou, Yi-Han, Jiang, Ya-Nan, Shao, Li-Wei, Wang, Shan-Jie, Wang, Xian-Qiang“…Operation arm #1 was located between the left anterior axillary line, the navel, and the costal margin (8 mm); operation arm #2 was located at the intersection of the right anterior axillary line and Pfannenstiel line (8 mm); one auxiliary hole was located between arm #2 (on the Pfannenstiel line) and the observation hole (12 mm); and another auxiliary hole (5 mm) was located slightly below the left side of the xiphoid. …”
Publicado 2019
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47627por Wunderink, Richard G, Wunderink, Richard G, Matsunaga, Yuko, Ari, Mari, Ariyasu, Mari, Echols, Roger, Echols, Roger, Menon, Anju, Den Nagata, Tsutae, Den Nagata, Tsutae“…The primary endpoint was non-inferiority of CFDC to MEM for Day 14 ACM rate in the modified intent-to-treat population (mITT; non-inferiority margin: –12.5%). Key secondary endpoints were clinical and microbiological outcomes at test of cure (TOC), and Day 28 mortality. …”
Publicado 2019
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47628“…MWT was performed for patients who refused to have OPN or in those cases where the collecting system, renal calyx, and great vessels were free from tumor margins of more than 1 cm. Results: In the MWT group a median (IQR) patients’ age was 75 years (71–79) years, in the OPN group—71.5 (70–75) years, p = 0.005. …”
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47629por Yang, Yong-Le, Qin, Pan, Wang, Bin, Liu, Yan, Xu, Guo-Han, Peng, Lei, Zhou, Jiyong, Zhu, Shu Jeffrey, Huang, Yao-Wei“…SADS-CoV nonstructural proteins and double-stranded RNA were detected in splenocytes of the marginal zone on the edge of lymphatic follicles, indicating active replication of SADS-CoV in the mouse model. …”
Publicado 2019
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47630por Mathias, Priyanka, Manavalan, Anjali, Aleksic, Sandra, Bloomgarden, Noah, Schubart, Ulrich“…There were focal areas of tumor necrosis, 3 foci of capsular invasion, and extensive angioinvasion. Surgical margins were free of tumor invasion. Eight resected lymph nodes were negative for malignancy (Stage T1bN0M1; AJCC 8, Stage IVb). …”
Publicado 2020
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47631por Bissegatto, Débora Delmonte, Fernandes, Bianca Helena Ventura, da Silva, Caroline Caetano, Chen, Wenbiao, Junqueira, Mara de Souza, Carvalho, Luciani Renata Silveira“…PROP1 gene is responsible for progenitor cell migration from the marginal zone to the anterior lobe, and its terminal differentiation into corticotropes and gonadotropes cell lines besides somatotropes, lactotropes and thyrotropes due to POU1F1 (also known as PIT1) activation. …”
Publicado 2020
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47632por Deal, Cheri L, Pastrak, Aleksandra, Silverman, Lawrence A, Valluri, Srinivas Rao, Wajnrajch, Michael Paul, Cara, Jose Francisco“…The lower bound of the two-sided 95% confidence interval of the treatment difference was -0.39, which was higher than the pre-established non-inferiority margin and demonstrated non-inferiority of once weekly somatrogon vs daily Genotropin therapy. …”
Publicado 2020
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47633por Perez, Paola M, Fu, Polly, Folick, Andrew, Ku, Gregory Michael, Shoback, Dolores M, Lee, Janet Yi Man“…Pathology was consistent with a phosphaturic mesenchymal tumor, but clear margins could not be confirmed due to intraoperative tumor fragmentation. …”
Publicado 2020
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47634por Correia, Jorge César, Meraj, Hafsa, Teoh, Soo Huat, Waqas, Ahmed, Pataky, Zoltan, Golay, Alain“…Major strategies included health record keeping, follow ups, reminders, psychoeducation, glucose monitoring, monitoring prompts, alerts and online consultations Overall, a significant treatment effect was seen among outcomes of HbA1c (SMD=-0.30, 95% CI= -0.42 to -0.17, n=6548, I(2)= 80.21%) and fasting blood sugar levels (SMD=-0.17, 95% CI= -0.32 to -0.01, n=4709, I(2)=60.49%), self-efficacy (SMD= 1.94, 95% CI= 1.31 to 2.58, n=626, I(2)= 95.99) and treatment adherence (SMD= 1.16, 95% CI= 0.78 to 1.54, n=437, I(2)= 84.8%). A marginally significant effect was seen in improvement of knowledge regarding diabetes (SMD= 0.66, 95% CI= -0.006 to 1.33, n=1345, I(2)= 93.38%). …”
Publicado 2020
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47635por Mora, Pablo, Sutton, David R, Gore, Ashwini, Baliga, Bantwal S, Goldfaden, PharmD, Rebecca, Nikkel, Carla, Sink II, John, Adams-Huet, Beverley“…The mean change in HbA1c with RHI was -0.60% from a baseline of 8.41% vs -0.38% from a baseline of 8.33% with RAI (estimated treatment difference [ETD]: -0.22%; 95% confidence interval [CI] -0.67% to 0.22%; non-inferiority margin<0.4% and p=0.007). The mean change in TDD with RHI was 0.8 U/day from a baseline of 61.0 U/day vs 1.8 U/day from a baseline of 61.3 U/day with RAI (ETD: -1.04 U/day; 95% CI: -3.18 U/day to 1.11 U/day; p=0.92). …”
Publicado 2020
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47636“…Sestamibi scan showed intense tracer uptake within a nodule near the suprasternal notch, and parathyroid 4D-CT showed a left 17mm pretracheal lesion with cystic degeneration along the superior margin of the manubrium. The patient subsequently underwent parathyroidectomy of an ectopic cystic mass with normalization of calcium and PTH levels. …”
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47637por Sumiyoshi, Chika, Narita, Zui, Inagawa, Takuma, Yamada, Yuji, Sueyoshi, Kazuki, Hasegawa, Yumi, Shirama, Aya, Hashimoto, Ryota, Sumiyoshi, Tomiki“…RESULTS: The correlational coefficient for the frequent items (DOG, CAT, ELEPAHANT, GIRAFFE, LION, TIGER) between patients and healthy controls was considerably higher at the follow-up (r=0.58) compared to that at base line (r=0.12), reaching a marginal significance (p=0.058). A visual inspection for the cosine profiles of frequent items indicated that distinct clusters of Pet (DOG, CAT), Wild-Herbivorous (ELEPAHANT, GIRAFFE), and Wild-Carnivorous (LION, TIGER) in patients at follow-up, as in the case for healthy controls. …”
Publicado 2020
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47638por Abadpour, Shadab, Tyrberg, Björn, Schive, Simen W., Huldt, Charlotte Wennberg, Gennemark, Peter, Ryberg, Erik, Rydén-Bergsten, Tina, Smith, David M., Korsgren, Olle, Skrtic, Stanko, Scholz, Hanne, Winzell, Maria Sörhede“…Administration of the GPR44 antagonist for up to 17 days to diabetic mice transplanted with a marginal number of human islets resulted in reduced fasting blood glucose and lower glucose excursions during IVGTT. …”
Publicado 2020
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47639por Drukker, Lior, Staines-Urias, Eleonora, Villar, José, Barros, Fernando C., Carvalho, Maria, Munim, Shama, McGready, Rose, Nosten, Francois, Berkley, James A., Norris, Shane A., Uauy, Ricardo, Kennedy, Stephen H., Papageorghiou, Aris T.“…Only a very small proportion (2.8%–6.5%) of the variance of Doppler indices was due to between-site differences; in addition, standardized site difference estimates were marginally outside this threshold in only 1 of 27 comparisons, and this supported the decision to pool data from the 3 study sites. …”
Publicado 2020
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47640por Lewis, John E., Atlas, Steven E., Abbas, Muhammad H., Rasul, Ammar, Farooqi, Ashar, Lantigua, Laura A., Michaud, Frederick, Goldberg, Sharon, Lages, Lucas C., Gao, Jinrun, Higuera, Oscar L., Fiallo, Andrea, Harvey, Philip D., Tiozzo, Eduard, Woolger, Judi M., Ciraula, Stephanie, Mendez, Armando, Rodriguez, Allan, Konefal, Janet“…Time contrasts showed that a difference in the overall dependent variable did not occur from baseline to 3 months (F[1, 104]=2.7, P=0.10), marginally occurred from baseline to 6 months (F[1, 104]=3.2, P=0.08), and was significant from 3 to 6 months (F[1, 104]=6.43, P=0.01). …”
Publicado 2020
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