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47701por Wang, Yan, Wang, Chengtao, He, Shasha, Bai, Li, Kong, Fei, Wang, Siyang, Cui, Lei, Qin, Qiang, Yang, Yunying, Xiao, Wei, Zhu, Meiyan, Zhang, Zeyu, Lai, Yulin, Bao, Wenjing, Peng, Zhenwei, Chen, Yong“…The trial was stopped early because of strong evidence for noninferiority (margin was -10%) of TP in failure-free survival. Efficacy analyses were performed in both the intention-to-treat and per-protocol trial populations and we included the patients who started treatment in each group for the safety analysis. …”
Publicado 2022
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47702por Jiang, Wei-Zhong, Xu, Jian-Min, Xing, Jia-Di, Qiu, Hui-Zhong, Wang, Zi-Qiang, Kang, Liang, Deng, Hai-Jun, Chen, Wei-Ping, Zhang, Qing-Tong, Du, Xiao-Hui, Yang, Chun-Kang, Guo, Yin-Cong, Zhong, Ming, Ye, Kai, You, Jun, Xu, Dong-Bo, Li, Xin-Xiang, Xiong, Zhi-Guo, Tao, Kai-Xiong, Ding, Ke-Feng, Zang, Wei-Dong, Feng, Yong, Pan, Zhi-Zhong, Wu, Ai-Wen, Huang, Feng, Huang, Ying, Wei, Ye, Su, Xiang-Qian, Chi, Pan“…The rate of negative circumferential and distal resection margins was 98.2% (673 of 685) vs 99.7% (353 of 354) (difference, −1.5%; 95% CI, −2.8% to 0.0%; P = .09) and 99.4% (681 of 685) vs 100% (354 of 354) (difference, −0.6%; 95% CI, −1.5% to 0.5%; P = .36), respectively. …”
Publicado 2022
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47703por Choudhary, Sidhya, Mishra, Ramesh kumar, Vyas, Aruna, Pathan, Nazneen, Gupta, Karuna“…In MRI a well-defined irregularly marginated hyperintense focal lesion was found in left iliac bone with joint effusion suggestive of infective etiology, tubercular, or less likely metastasis. …”
Publicado 2022
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47704por España, Jaime David Acosta, Altamirano-Jara, Belén, Lafuente-Cevallos, Lizeth, Lascano-Gallegos, Natalie, Voigt, Kerstin, Palacios-Alvarez, Santiago“…A punch biopsy of the affected region was requested, and specimens were sent for culture, histopathology, and smears from the margins of the lesion to rule out leshmaniasis. As shown in Figure 1c, a histopathology report was submitted with yeast-like structures with multiple branches and a positive culture for Paracoccidiodes (Fig. 1d). …”
Publicado 2022
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47705por Loebner, Hannes A., Volken, Werner, Mueller, Silvan, Bertholet, Jenny, Mackeprang, Paul‐Henry, Guyer, Gian, Aebersold, Daniel M., Stampanoni, Marco F. M., Manser, Peter, Fix, Michael K.“…For all evaluated plans and uncertainties, the planning target volume (PTV) margin prevented major clinical target volume (CTV) coverage deterioration (maximum observed standard deviation of [Formula: see text] was 1.3 Gy). …”
Publicado 2022
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47706por Sherr, Lorraine, Haag, Katharina, Steventon Roberts, Kathryn J, Cluver, Lucie Dale, Wittesaele, Camille, Saliwe, Bongiwe, Tolmay, Janke, Langwenya, Nontokozo, Jochim, Janina, Saal, Wylene, Zhou, Siyanai, Marlow, Marguerite, Chen-Charles, Jenny J, Toska, Elona“…Hierarchical regression analyses suggest marginal predictive effects of being second-generation child compared with having a mother not living with HIV (B=−3.3, 95% CI=−6.8 to 0.1) on MSEL total scores, and non-significant predictive effects of being a third-generation child (B=1.1, 5% CI=−7.5 to 9.7) when controlling for covariates. …”
Publicado 2022
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47707por Zweiphenning, Willemiek, Klooster, Maryse A van 't, van Klink, Nicole E C, Leijten, Frans S S, Ferrier, Cyrille H, Gebbink, Tineke, Huiskamp, Geertjan, van Zandvoort, Martine J E, van Schooneveld, Monique M J, Bourez, M, Goemans, Sophie, Straumann, Sven, van Rijen, Peter C, Gosselaar, Peter H, van Eijsden, Pieter, Otte, Willem M, van Diessen, Eric, Braun, Kees P J, Zijlmans, Maeike“…We predefined a non-inferiority margin of 10% risk difference. Analysis was by intention to treat, with prespecified subgroup analyses by epilepsy type and for confounders. …”
Publicado 2022
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47708por Pahwa, Dhivya, Vanaparthy, Swati, Ababio, Priscilla, Ahmed, Wefag Kamil, Mammadova, Aytan, Ganta, Vijaya, Zenebe, Anteneh, Nunlee-Bland, Gail, Odonkor, Wolali“…CT of the neck showed a prominent soft tissue mass on the right side of the neck with irregular margins abutting the right thyroid lobe, suggesting possible abscess. …”
Publicado 2022
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47709por Grimberg, Adda, Friedrich, Elizabeth, Faig, Walter, Kamoun, Camilia, Fremont, Ettya, Xiao, Rui, Miller, Victoria“…Univariate models with Holm-Bonferroni correction of significance level 0.05 assessed the marginal effect of each factor on QoL and self-esteem outcomes. …”
Publicado 2022
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47710por Babu, Vedesh Kumar, Suravajjala, Devi, Kolli, Swapna, Eranki, Madhuri, Eranki, Vijay“…MRI brain then showed a sellar mass of 2.4×2.6×2.7 cm with sphenoid sinus extension and bony thinning alongthe margins of the sella turcica which was nearly imperceptible. …”
Publicado 2022
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47711“…Pathology for left nodule showed sclerosing mucoepidermoid carcinoma with eosinophils, 8.6×6.9×5.8 cm, p T4a N×Mx, with positive margins for tumor, no angiolymphatic invasion with co-existing right-sided papillary microcarcinoma (follicular variant) with chronic lymphocytic thyroiditis. …”
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47712por Ortiz-Rivera, Monica, Ortega, Nydia Burgos, Madera-Marin, Luis, Burgos, Alexandra Rosado, Cordero, Nicole Hernandez, Musa-Pena, Laurianne E, Nieves, Yadiel Rivera, Vick, Margarita Ramirez, Santiago, Milliette Alvarado, Rodriguez, Loida Gonzalez“…Histology consistent with a low-grade ACC with a mitotic rate 18/50 HPF, with capsular invasion but no lymphovascular invasion and clear margins. It was stratified as stage T2N0M0. Immunohistochemistry's were positive for Melan-A, calretinin, synaptophysin, and inhibin. …”
Publicado 2022
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47713por Azmath, Misbah, Bendaram, Snigdha, Igarashi, Yuichi, Aftab, Hassaan, Malchoff, Carl“…Final pathology revealed a 5.3 cm left pheochromocytoma with negative surgical margins. Germline genetic testing was negative for pheochromocytoma/paraganglioma pathogenic gene mutations, and an MIBG scan did not reveal metastatic disease. …”
Publicado 2022
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47714“…Pathology revealed 11.5cm low-grade adrenocortical carcinoma with clear margins and angioinvasion, Ki67 proliferation index of 1-2%, and without necrosis, lymphovascular invasion, or extra-adrenal extension. 11-deoxycortisol normalized and DOC was undetectable at one and three months postoperatively. …”
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47715por Murvelashvili, Natia, Polanco, Patricio, Khorsand, Sarah, Marrero, Jorge, Jia, Liwei, Mirfakhraee, Sasan, Else, Tobias, Habra, Mouhammed, Cole, Suzanne, Hamidi, Oksana“…Histopathology showed a necrotic ACC with tumor invasion into the adrenal capsule, no lymphovascular invasion, margins uninvolved, and Ki-67 index of 40%. Kidney parenchyma exhibited diffuse pigment casts. …”
Publicado 2022
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47716“…Pathology revealed a 0.5cm deposit on the largest dimension, clear margins, and no angiovascular, or lymphovascular invasion, surgery was complicated by hypoparathyroidism. …”
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47717por Reeves, Alexis, Elliott, Michael R., Lewis, Tené T., Karvonen-Gutierrez, Carrie A., Herman, William H., Harlow, Siobán D.“…However, most studies neither evaluate differences in age at onset nor account for systematic exclusion stemming from “weathering” (accelerated health declines for minoritized groups due to structural social and economic marginalization). OBJECTIVE: To evaluate racial or ethnic disparities in age at onset of 4 cardiometabolic outcomes (hypertension, isolated systolic hypertension [ISH], insulin resistance [IR], and diabetes), accounting for multiple forms of potential selection bias. …”
Publicado 2022
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47718por Hill, Jonathan C, Garvin, Stefannie, Bromley, Kieran, Saunders, Benjamin, Kigozi, Jesse, Cooper, Vince, Lewis, Martyn, Protheroe, Joanne, Wathall, Simon, Chudyk, Adrian, Dunn, Kate M, Birkinshaw, Hollie, Jowett, Sue, Hay, Elaine M, van der Windt, Danielle, Mallen, Christian, Foster, Nadine E“…The costs of risk-based stratified care were similar to usual care, and such a strategy only offers marginal changes in cost-effectiveness outcomes. The clinical implications from this trial are largely inconclusive. …”
Publicado 2022
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47719por Azam, Mohammad T., Weiss, Matthew B., Colasanti, Christopher, Brodeur, Peter G., Ubillus, Hugo A., Kennedy, John G.“…Having a shoulder lesion had the largest marginal effect on post-operative FAOS. These findings provide important information for providers when counseling and selecting patients for AOT procedure for treatment of OLT.…”
Publicado 2022
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47720por Lundy, Alexander, Colantonio, Donald, Le, Anthony, Lee, Richard C., Piscoya, Andres S., Holm, Erik, Eckel, Tobin T.“…Changes in contact pressure and area were compared with two-way repeated measure analysis of variance and significant findings were tested with post-hoc pairwise comparisons of estimated marginal means with Bonferroni-adjusted p-values for multiple comparisons (α = 0.05). …”
Publicado 2022
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