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47741por Kovacs, Boldizsar, Mayinger, Michael, Ehrbar, Stefanie, Fesslmeier, Debra, Ahmadsei, Maiwand, Sazgary, Lorraine, Manka, Robert, Alkadhi, Hatem, Ruschitzka, Frank, Duru, Firat, Papachristofilou, Alexandros, Sticherling, Christian, Blamek, Slawomir, Gołba, Krzysztof S., Guckenberger, Matthias, Saguner, Ardan M., Andratschke, Nicolaus“…The trial aims to escalate the ITV dose from 27.0 Gy to an ITV prescription dose-equivalent level of maximum 35.1 Gy by keeping the PTV prescription dose constant at 25 Gy while increasing the dose to the target (i.e. the VT substrate without PTV margin) by step-wise reduction of the prescribing isodose line (85% down to 65%). …”
Publicado 2023
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47742por Atakpa, Emma C., Buist, Diana S. M., Aiello Bowles, Erin J., Cuzick, Jack, Brentnall, Adam R.“…Discriminatory accuracy was marginally greater for longitudinal versus BI-RADS density (c-index = 0.64 vs. 0.63, mean difference = 0.008, 95% CI 0.003–0.012). …”
Publicado 2023
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47743por Lee, Heesun, Park, Jun-Bean, Choi, Sae Won, Yoon, Yeonyee E, Park, Hyo Eun, Lee, Sang Eun, Lee, Seung-Pyo, Kim, Hyung-Kwan, Cho, Hyun-Jai, Choi, Su-Yeon, Lee, Hae-Young, Choi, Jonghyuk, Lee, Young-Joon, Kim, Yong-Jin, Cho, Goo-Yeong, Choi, Jinwook, Sohn, Dae-Won“…In patients with good adherence to ICT-based telehealth program, there was a significant improvement in the mean uNa (103.1 to 78.1; P=.01) but not in those without (85.4 to 96.9; P=.49). Similarly, a marginal improvement in MLHFQ scores was only observed in patients with good adherence (27.5 to 21.4; P=.08) but not in their counterparts (19.0 to 19.7; P=.73). …”
Publicado 2017
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47744por Lawrence, David S., Youssouf, Nabila, Molloy, Síle L. F., Alanio, Alexandre, Alufandika, Melanie, Boulware, David R., Boyer-Chammard, Timothée, Chen, Tao, Dromer, Francoise, Hlupeni, Admire, Hope, William, Hosseinipour, Mina C., Kanyama, Cecilia, Lortholary, Oliver, Loyse, Angela, Meya, David B., Mosepele, Mosepele, Muzoora, Conrad, Mwandumba, Henry C., Ndhlovu, Chiratidzo E., Niessen, Louis, Schutz, Charlotte, Stott, Katharine E., Wang, Duolao, Lalloo, David G., Meintjes, Graeme, Jaffar, Shabbar, Harrison, Thomas S., Jarvis, Joseph N.“…The primary endpoint is all-cause mortality at ten weeks with a non-inferiority margin of 10% and 90% power. Secondary endpoints are early fungicidal activity, proportion of grade III/IV adverse events, pharmacokinetic parameters and pharmacokinetic/pharmacodynamic associations, health service costs, all-cause mortality within the first two and four weeks, all-cause mortality within the first ten weeks (superiority analysis) and rates of CM relapse, immune reconstitution inflammatory syndrome and disability at ten weeks. …”
Publicado 2018
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47745por Nama, Nassr, Sampson, Margaret, Barrowman, Nicholas, Sandarage, Ryan, Menon, Kusum, Macartney, Gail, Murto, Kimmo, Vaccani, Jean-Philippe, Katz, Sherri, Zemek, Roger, Nasr, Ahmed, McNally, James Dayre“…Finally, when a simple majority threshold was considered, sensitivity decreased marginally to 98.9% (95% CI 96.0-99.7; P=.25) and work performed increased substantially to 80.4% (95% CI 78.7-82.0; P<.001). …”
Publicado 2019
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47746por Maclachlan, Liam R, Mills, Kathryn, Lawford, Belinda J, Egerton, Thorlene, Setchell, Jenny, Hall, Leanne M, Plinsinga, Melanie L, Besomi, Manuela, Teo, Pek Ling, Eyles, Jillian P, Mellor, Rebecca, Melo, Luciano, Robbins, Sarah, Hodges, Paul W, Hunter, David J, Vicenzino, Bill, Bennell, Kim L“…Qualitative and quantitative studies identified empowerment, social support, self-management behavior, and health literacy as primary constructs to measure OSG efficacy. Neutral or marginal improvement was reported in these constructs. …”
Publicado 2020
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47747por Li, Jiahao, Li, Huixian, Wu, Huiying, Niu, Huilin, Li, Haibo, Pan, Jing, Yang, Jiliang, Tan, Tianbao, Hu, Chao, Xu, Tao, Zhang, Xiaohong, Zheng, Manna, Li, Kuanrong, Zou, Yan, Yang, Tianyou“…Seven tumours were associated with positive surgical margins, and 12 patients had microvascular involvement. …”
Publicado 2020
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47748por Tan, Dingyu, Walline, Joseph Harold, Ling, Bingyu, Xu, Yan, Sun, Jiayan, Wang, Bingxia, Shan, Xueqin, Wang, Yunyun, Cao, Peng, Zhu, Qingcheng, Geng, Ping, Xu, Jun“…The treatment failure rate in the HFNC group was 22.7% and 28.6% in the NIV group—risk difference of − 5.8% (95% CI, − 23.8–12.4%, p = 0.535), which was significantly lower than the non-inferior margin of 9%. Analysis of the causes of treatment failure showed that treatment intolerance in the HFNC group was significantly lower than that in the NIV group, with a risk difference of − 50.0% (95% CI, − 74.6 to − 12.9%, p = 0.015). …”
Publicado 2020
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47749por Hill, Brandon J, Motley, Darnell N, Rosentel, Kris, VandeVusse, Alicia, Garofalo, Robert, Schneider, John A, Kuhns, Lisa M, Kipke, Michele D, Reisner, Sari, Rupp, Betty M, Sanchez, Maria, McCumber, Micah, Renshaw, Laura, Loop, Matthew Shane“…Experiences of discrimination and marginalization often limit educational attainment and may even more directly limit access to gainful employment. …”
Publicado 2020
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47750por Wang, Hongyi, Zhang, Jing, Chu, Zhenxing, Hu, Qinghai, Dong, Willa, Huang, Xiaojie, Chen, Yaokai, Wang, Hui, He, Xiaoqing, Zhang, Lukun, Hu, Zhili, Bao, Rantong, Li, Shangcao, Li, Hang, Cui, Sitong, Jin, Xia, Ding, Haibo, Geng, Wenqing, Jiang, Yongjun, Xu, Junjie, Shang, Hong“…In the event-driven group, GSN apps’ users had marginally lower levels of self-reported adherence (aOR 0.7, 95% CI 0.4-1.0, P=.060) and lower PrEP coverage of sexual practices (aOR 0.6, 95% CI 0.4-1.0, P=.038). …”
Publicado 2020
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47751por Ramallo-Fariña, Yolanda, García-Bello, Miguel Angel, García-Pérez, Lidia, Boronat, Mauro, Wägner, Ana M, Rodríguez-Rodríguez, Leticia, de Pablos-Velasco, Pedro, Llorente Gómez de Segura, Ignacio, González- Pacheco, Himar, Carmona Rodríguez, Montserrat, Serrano-Aguilar, Pedro“…RESULTS: For the overall sample, the intervention for patients attained a significant mean reduction in HbA(1c) levels of ‒0.27 (95% CI ‒0.45 to ‒0.10) at month 3 and ‒0.26 (95% CI ‒0.44 to ‒0.08) at month 6 compared with usual care, which remained marginally significant at month 12. A clinically relevant reduction in HbA(1c) level was observed in 35.6% (191/537) of patients in the intervention for patients and 26.0% (152/586) of those in usual care at month 12 (P=.006). …”
Publicado 2020
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47752por Chappell, Kimberly, Paarlberg, Tandy, Seewald, Wolfgang, Karadzovska, Daniela, Nanchen, Steve“…BACKGROUND: Studies show that the novel isoxazoline, lotilaner (Credelio™ CAT; Elanco Animal Health), which is administered orally to cats, provides rapid and sustained flea kill for least 1 month following administration with a wide safety margin. A clinical trial was undertaken to confirm its efficacy, impact on flea allergy dermatitis (FAD) and safety under field conditions. …”
Publicado 2021
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47753por DiPietro, Loretta, Bingenheimer, Jeffrey, Talegawkar, Sameera A., Sedlander, Erica, Yilma, Hagere, Pradhan, Pratima, Rimal, Rajiv“…Hemoglobin concentration was marginally associated with work capacity in the presence of the other covariables (β = 0.22; 95% CI:-0.02, 0.47). …”
Publicado 2021
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47754por Shewchuk, Brittany, Green, Lee A, Barber, Tanya, Miller, Jean, Teare, Sylvia, Campbell-Scherer, Denise, Mrklas, Kelly J, Li, Linda C, Marlett, Nancy, Wasylak, Tracy, Lopatina, Elena, McCaughey, Deirdre, Marshall, Deborah A“…Following the 6-week evaluation, patients reported a mean System Usability Scale (SUS) score of 57.8, indicating marginal acceptability according to SUS cutoffs. The mean number of goals set during the usability period was 2.47 (SD 3.08), and the mean number of activities completed for knee OA self-management during the study period was 22.2 (SD 17.8). …”
Publicado 2021
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47755por Anguita-Ruiz, Augusto, Zarza-Rebollo, Juan Antonio, Pérez-Gutiérrez, Ana M, Molina, Esther, Gutiérrez, Blanca, Bellón, Juan Ángel, Moreno-Peral, Patricia, Conejo-Cerón, Sonia, Aiarzagüena, Jose María, Ballesta-Rodríguez, M Isabel, Fernández, Anna, Fernández-Alonso, Carmen, Martín-Pérez, Carlos, Montón-Franco, Carmen, Rodríguez-Bayón, Antonina, Torres-Martos, Álvaro, López-Isac, Elena, Cervilla, Jorge, Rivera, Margarita“…The highest predictive ability for depression was achieved when the model included an interaction term between the GRS and the body mass index (BMI), apart from the inclusion of classical demographic information as marginal terms (AUC = 0.71, 95% CI = [0.65, 0.76]). …”
Publicado 2022
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47756por Fang, Hao Sen Andrew, Gao, Qiao, Tan, Wei Ying, Lee, Mong Li, Hsu, Wynne, Tan, Ngiap Chuan“…CONCLUSION: The real-world data on Asians with T2DM in this study show that the magnitudes of OAD initiation and dose titration are marginally lower than the results from clinical trials. …”
Publicado 2022
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47757por Crabtree-Ramirez, Brenda, Jenkins, Cathy A., Shepherd, Bryan E., Jayathilake, Karu, Veloso, Valdilea G., Carriquiry, Gabriela, Gotuzzo, Eduardo, Cortes, Claudia P., Padgett, Dennis, McGowan, Catherine, Sierra-Madero, Juan, Koenig, Serena, Pape, Jean W., Sterling, Timothy R.“…CONCLUSIONS: TB treatment 5–7 days/week was associated with a marginally decreased risk of death compared to TB treatment 2–3 days/week in the continuation phase in multivariable, unstratified analyses. …”
Publicado 2022
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47758por Chen, Nan, Xing, Changying, Niu, Jianying, Liu, Bicheng, Fu, Junzhou, Zhao, Jiuyang, Ni, Zhaohui, Wang, Mei, Liu, Wenhu, Zhao, Jinghong, Zhong, Ling, Wu, Xiongfei, Li, Wenge, Chen, Yuqing, Shi, Wei, Chen, Jianghua, Yin, Aiping, Fu, Ping, Wang, Rong, Jiang, Gengru, Hou, Fanfan, Ding, Guohua, Chen, Jing, Xu, Gang, Kondo, Yuichiro, Su, Yuliang, Mei, Changlin“…The primary efficacy profile was the mean Hb level (the non‐inferiority margin was −1.0 g/dL, week 21–28); the secondary efficacy profiles were the Hb increase rate (week 0–4), the target Hb achievement cumulative rate and time, the change trends of the Hb levels, and the target Hb maintenance ratio. …”
Publicado 2022
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47759por Humes, Sara T., Iovine, Nicole, Prins, Cindy, Garrett, Timothy J., Lednicky, John A., Coker, Eric S., Sabo-Attwood, Tara“…After adjustment for confounders (smoking status and pulmonary comorbidities), the odds ratio (OR) became only marginally significant (p = 0.099), but the magnitude of the effect estimate was similar (OR = 16.00 [0.59, 433.03]). …”
Publicado 2022
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47760por Brinster, Clayton J., Escousse, G. Thomas, Rivera, Phillip A., Sternbergh, W. Charles, Money, Samuel R.“…Our results have demonstrated a progressive, drastic increase in nursing labor costs during the pandemic, with a resultant sustained erosion of financial margins despite a level of clinical productivity, as measured in RVUs, equal to the prepandemic standards. …”
Publicado 2022
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