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47781por Zamboglou, Constantinos, Peeken, Jan C., Janbain, Ali, Katsahian, Sandrine, Strouthos, Iosif, Ferentinos, Konstantinos, Farolfi, Andrea, Koerber, Stefan A., Debus, Juergen, Vogel, Marco E., Combs, Stephanie E., Vrachimis, Alexis, Morganti, Alessio Giuseppe, Spohn, Simon K. B., Shelan, Mohamed, Aebersold, Daniel M., Grosu, Anca-Ligia, Ceci, Francesco, Henkenberens, Christoph, Kroeze, Stephanie G. C., Guckenberger, Matthias, Fanti, Stefano, Belka, Claus, Bartenstein, Peter, Hruby, George, Scharl, Sophia, Wiegel, Thomas, Emmett, Louise, Arnoux, Armelle, Schmidt-Hegemann, Nina-Sophie“…On multivariable Cox proportional hazards regression analysis, pre-sRT PSA level (hazard ratio [HR], 1.80 [95% CI, 1.41-2.31]), International Society of Urological Pathology grade in surgery specimen (grade 5 vs 1+2: HR, 2.39 [95% CI, 1.63-3.50], pT stage (pT3b+pT4 vs pT2: HR, 1.91 [95% CI, 1.39-2.67]), surgical margins (R0 vs R1+R2+Rx: HR, 0.60 [95% CI, 0.48-0.78]), ADT use (HR, 0.49 [95% CI, 0.37-0.65]), sRT dose (>70 vs ≤66 Gy: HR, 0.44 [95% CI, 0.29-0.67]), and nodal recurrence detected on PSMA-PET scans (HR, 1.42 [95% CI, 1.09-1.85]) were associated with FFBF. …”
Publicado 2023
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47782por Lewis, Francesca, Oakley, Robert, Hatch, Jennifer, Elst, Zoë Vander, Smits, Anne, Duffy, Donovan“…Due to vancomycin’s narrow therapeutic margin, daily therapeutic drug monitoring (TDM) of serum concentrations is necessary to obtain safe/effective therapy. …”
Publicado 2023
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47783por Chen, Weiming, Ao, Yang, Lan, Xiaochun, Tong, Wenzhou, Liu, Xiaohui, Zhang, Xia, Ye, Qiang, Li, Yin, Liu, Linfen, Ye, Hao, Zhuang, Pan, Zhang, Yu, Zheng, Weifang, Jiao, Jingjing“…Consumption of n-6 PUFAs (HR(Q4vsQ1) 1.13, 95% CI: 0.99–1.28; P-trend = 0.014) and linoleic acid (LA) (HR(Q4vsQ1) 1.11, 95% CI: 0.98–1.26; P-trend = 0.020) had marginal and positive relationships with the incidence of overweight/obesity. …”
Publicado 2023
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47784por Kimathi, Derick, Juan-Giner, Aitana, Orindi, Benedict, Grantz, Kyra H, Bob, Ndeye S, Cheruiyot, Stanley, Hamaluba, Mainga, Kamau, Naomi, Fall, Gamou, Dia, Moussa, Mosobo, Moses, Moki, Felix, Kiogora, Kenneth, Chirro, Oscar, Thiong'o, Alexander, Mwendwa, Jane, Guantai, Andrew, Karanja, Henry K, Gitonga, John, Mugo, Daisy, Ramko, Kelly, Faye, Ousmane, Sanders, Eduard J, Grais, Rebecca F, Bejon, Philip, Warimwe, George M“…We set a non-inferiority margin of not less than a 17% decrease in seroconversion in the fractional dose compared with the standard dose. …”
Publicado 2023
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47785por Ma, Jianglei, Xu, Weidong, Chen, Rui, Zhu, Yasheng, Wang, Ye, Cao, Wanli, Ju, Guanqun, Ren, Jizhong, Ye, Xiaofei, He, Qian, Chang, Yifan, Ren, Shancheng“…For RCTs, meta-analysis showed that RARP and LRP were similar in blood loss, catheter indwelling time, overall complication rate, overall positive surgical margin and biochemical recurrence rates, but quantitative synthesis of non-randomised studies showed that RARP was associated with less blood loss [weighted mean difference (WMD)=−71.99, 95% CI −99.37 to −44.61, P<0.001], shorter catheterization duration (WMD=−1.03, 95% CI −1.84 to −0.22, P=0.010), shorter hospital stay (WMD=−0.41, 95% CI −0.68 to −0.13, P=0.004), lower transfusion rate (OR=0.44, 95% CI 0.35–0.56, P<0.001), lower overall complication rate (OR=0.72, 95% CI 0.54–0.96, P=0.020), and lower biochemical recurrence rate (OR=0.78, 95% CI 0.66–0.92, P=0.004), compared with LRP. …”
Publicado 2023
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47786por Jyani, Gaurav, Yang, Zhihao, Sharma, Atul, Goyal, Aarti, Stolk, Elly, Purba, Fredrick Dermawan, Grover, Sandeep, Kaur, Manmeet, Prinja, Shankar“…Extending the design with inclusion of more health states marginally improves the predictive performance even when the sample size was fixed at 1,000. …”
Publicado 2023
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47787“…CONCLUSIONS: When offered maintenance medications through community and mail order pharmacies on a benefit-equivalent basis, commercially insured employees and their dependents utilized the community pharmacy channel more frequently by a margin of more than 4 to 1 in terms of claims PMPY. …”
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47788por James, Sarah-Naomi, Manning, Emily N, Storey, Mathew, Nicholas, Jennifer M, Coath, William, Keuss, Sarah E, Cash, David M, Lane, Christopher A, Parker, Thomas, Keshavan, Ashvini, Buchanan, Sarah M, Wagen, Aaron, Harris, Mathew, Malone, Ian, Lu, Kirsty, Needham, Louisa P, Street, Rebecca, Thomas, David, Dickson, John, Murray-Smith, Heidi, Wong, Andrew, Freiberger, Tamar, Crutch, Sebastian J, Fox, Nick C, Richards, Marcus, Barkhof, Frederik, Sudre, Carole H, Barnes, Josephine, Schott, Jonathan M“…Significant sex interactions (P < 0.05) emerged for midlife cardiovascular health (age 53) and normal-appearing white matter at 70: marginal effect plots demonstrated, in women only, normal-appearing white matter was associated with higher midlife Framingham Heart Study Cardiovascular Risk Score (lower fractional anisotropy and neurite density index), midlife systolic (lower fractional anisotropy, neurite density index and higher mean diffusivity) and diastolic (lower fractional anisotropy and neurite density index) blood pressure and greater blood pressure change between 43 and 53 years (lower fractional anisotropy and neurite density index), independently of white matter hyperintensity volume. …”
Publicado 2023
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47789por Pauciullo, Alfredo, Versace, Carmine, Gaspa, Giustino, Letaief, Neyrouz, Bedhiaf-Romdhani, Sonia, Fulgione, Andrea, Cosenza, Gianfranco“…A PCR-RFLP was set up for genotyping a dromedary Tunisian population (n = 157), and the minor allele frequency was found to be 0.27 for the G allele, indicating a potential yield improvement margin. The interspersed elements (INEs) analysis revealed 10 INEs covering 7.34% and 8.14% of the CSN1S2 sequence in the Bactrian and dromedary camels, respectively. …”
Publicado 2023
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47790“…Three of the causal proteins, SOCS3, FCGR3B, and NCF2, were enriched in the osteoclast differentiation pathway in KEGG enrichment analyses while GPC1 (marginal inclusion probability (MIP):0.993; model averaged causal effects (MACE): − 0.349), NAMPT (MIP:0.433; MACE: − 0.113), and NCF2 (MIP:0.324; MACE:0.066) ranked among the top three MM-associated proteins according to MR-BMA analyses. …”
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47791por Wang, Yeli, Liu, Binkai, Han, Han, Hu, Yang, Zhu, Lu, Rimm, Eric B., Hu, Frank B., Sun, Qi“…Among four studies that examined changes in dietary patterns, increased adherence to plant-based dietary patterns was associated with a significantly reduced risk of T2D (0.83 [0.71–0.96]; I(2) = 71.5%) and a marginally lower risk of mortality (0.95 [0.91–1.00]; I(2) = 0%). …”
Publicado 2023
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47792por Alzenaidi, Ahlam“…Pituitary MRI showed marked compression of the pituitary tissue with concave superior margins due to partially empty sella. She was maintained only on hydrocortisone replacement. …”
Publicado 2023
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47793“…Right superior parathyroidectomy revealed PC invasive into adipose tissue, increased vascularity and positive margins. A hemithyroidectomy and central neck dissection was performed with intraoperative report noting normal-appearing right inferior parathyroid affixed to thyroid, confirmed by frozen section biopsy. …”
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47794por Refardt, Julie, Atila, Cihan, Chifu, Irina Oana, Ferrante, Emanuele, Erlic, Zoran, Drummond, Juliana Beaudette, Mantovani, Beatrice, Drexhage, Roosmarijn, Sailer, Clara Odilia, Widmer, Andrea, Felder, Susan, Powlson, Andrew Stephen, Hutter, Nina, Vogt, Deborah, Gurnell, Mark, Rocha, Beatriz, Hofland, Johannes, Beuschlein, Felix, Fassnacht, Martin, Winzeler, Bettina Felicitas, Christ-Crain, Mirjam“…We hypothesized that arginine stimulated copeptin is non-inferior (non-inferiority margin 10%) to hypertonic saline stimulated copeptin for the diagnosis of cDI. …”
Publicado 2023
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47795por Wright, Charlene, Kelly, Jaimon T., Byrnes, Joshua, Campbell, Katrina L., Healy, Rebecca, Musial, Jane, Hamilton, Kyra“…The primary outcome measures included feasibility (via recruitment and retention rate), acceptability (via mixed methods), marginal costs, and weight 12 months postoperatively. …”
Publicado 2023
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47796por Netzer, Nils, Eith, Carolin, Bethge, Oliver, Hielscher, Thomas, Schwab, Constantin, Stenzinger, Albrecht, Gnirs, Regula, Schlemmer, Heinz-Peter, Maier-Hein, Klaus H., Schimmöller, Lars, Bonekamp, David“…The waFROC AUC was 0.67 (95% CI: 0.60–0.83) in A and 0.7 (95% CI: 0.64–0.78) in B. UNETM performed marginally better on readout-segmented than on single-shot echo-planar-imaging. …”
Publicado 2023
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47797por Rolle, Charlotte-Paige M, Castano, Jamie, Nguyen, Vu, Hinestrosa, Federico, DeJesus, Edwin“…A planned W24 interim analysis assessed noninferiority with a 6% margin. RESULTS: Overall, 222 adults (16% women; 51% aged ≥50 years; 28% Black) were randomized. …”
Publicado 2023
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47798“…Local activity during reduction of the safety margin for conduction was studied. 5. An analysis was made of high frequency grouped discharges which occasionally arise in cells. …”
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47799por Brand, Richard A.“…He used a wide transverse incision (Fig. 2) to access the hip, excising all lateral musculature along with the trochanter and the lateral margin of the acetabulum (Fig. 1). In the presence of infection in the intermuscular planes, he avoided suturing the skin deeply, and rather packed the wound with Vaseline gauze and rubber drains (Fig. 4). …”
Publicado 2008
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47800“…The use of pharmacotherapy and non-assigned treatment types showed a small but marginally significant correlation: r (1028) = .061, P = .05. …”
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