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  1. 47821
    “…SUMMARY ANSWER: Non-inferiority of oral dydrogesterone versus MVP was demonstrated at 12 weeks of gestation, with a difference in pregnancy rate and an associated confidence interval (CI) that were both within the non-inferiority margin. WHAT IS KNOWN ALREADY: MVP is routinely used in most clinics for luteal support in IVF, but it is associated with side effects, such as vaginal irritation and discharge, as well as poor patient acceptance. …”
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    A Phase III randomized controlled trial comparing the efficacy, safety and tolerability of oral dydrogesterone versus micronized vaginal progesterone for luteal support in in vitro fertilization
  2. 47822
    “…RESULTS: Wip1-KO mice had a marginally increased HW/BW ratio and slightly impaired cardiac function before LAD ligation. …”
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    Wild-type p53-induced Phosphatase 1 Deficiency Exacerbates Myocardial Infarction-induced Ischemic Injury
  3. 47823
    “…HAP plus EUC also had a marginal effect on WHO Disability Assessment Schedule score at 12 months (aPR = −1.58; 95% CI −3.33, 0.17; p = 0.08); other outcomes (days unable to work, intimate partner violence toward females) did not statistically significantly differ between the two arms. …”
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    Sustained effectiveness and cost-effectiveness of the Healthy Activity Programme, a brief psychological treatment for depression delivered by lay counsellors in primary care: 12-month follow-up of a randomised controlled trial
  4. 47824
    “…In the bridging oxalate ligand in 2 (2−), the C—O bond lengths are equalized, within the error margin of one bond-length determination (0.006 Å). …”
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    Coordination compounds containing bis-di­thiol­ene-chelated molybdenum(IV) and oxalate: comparison of terminal with bridging oxalate
  5. 47825
    “…One study demonstrated that fully digitally produced dental crowns revealed the feasibility of the process itself; however, the marginal precision was lower for lithium disilicate (LS2) restorations (113.8 μm) compared to conventional metal-ceramic (92.4 μm) and zirconium dioxide (ZrO2) crowns (68.5 μm) (p < 0.05). …”
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    The complete digital workflow in fixed prosthodontics: a systematic review
  6. 47826
    “…The introduction of GHIS led to a marginal increase (p > 0.05) in the average annual number of elective PCI in non-ACS setting as opposed to a 120% rise in the number of elective PCI done in the ACS setting (p < 0.001) and the delay in performing PCI after coronary angiogram reduced from 55.8 ± 43.6 days to 33 ± 22.9 days (p < 0.01). …”
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    Appropriateness of elective percutaneous coronary intervention and impact of government health insurance scheme — A tertiary centre experience from Western India
  7. 47827
    “…PTV ([Formula: see text] margin) volumes ranged from 10.0 to 99.9 cc ([Formula: see text]). …”
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    Technical Note: Dosimetric evaluation of Monte Carlo algorithm in iPlan for stereotactic ablative body radiotherapy (SABR) for lung cancer patients using RTOG 0813 parameters
  8. 47828
    “…The hippocampus was volumetrically contoured on fused diagnostic T1‐weighted MRI with planning CT images and hippocampus avoidance zone (HAZ) was generated using a 5 mm uniform margin around the hippocampus. Both hippocampi were defined as one paired organ. …”
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    Potential for reduced radiation‐induced toxicity using intensity‐modulated arc therapy for whole‐brain radiotherapy with hippocampal sparing
  9. 47829
    “…In the primary (complete-case) analysis at 144 weeks, 317 (86%) of 367 in the protease inhibitor plus NRTI group had viral loads of less than 400 copies per mL compared with 312 (81%) of 383 in the protease inhibitor plus raltegravir group (p=0·07; lower 95% confidence limit for difference 10·2% vs specified non-inferiority margin 10%). In the protease inhibitor monotherapy group, 292 (78%) of 375 had viral loads of less than 400 copies per mL; p=0·003 versus the protease inhibitor plus NRTI group at 144 weeks. …”
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    Lopinavir plus nucleoside reverse-transcriptase inhibitors, lopinavir plus raltegravir, or lopinavir monotherapy for second-line treatment of HIV (EARNEST): 144-week follow-up results from a randomised controlled trial
  10. 47830
    “…The addition of Lp(a) levels to a prognostic model for MCE and CVD revealed only a marginal but significant C-index discrimination measure increase (0.001 for MCE and CVD; P < 0.05) and net reclassification improvement (0.010 for MCE and 0.011 for CVD). …”
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    Lipoprotein(a) and the risk of cardiovascular disease in the European population: results from the BiomarCaRE consortium
  11. 47831
    “…Assuming a hazard ratio of 1.0, this provides 90% power to demonstrate non-inferiority of linagliptin versus placebo within the pre-specified non-inferiority margin of 1.3 at a one-sided α-level of 2.5%. If non-inferiority of linagliptin for the primary outcome is demonstrated, then its superiority for both the primary outcome and the key secondary outcome will be investigated with a sequentially rejective multiple test procedure. …”
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    Rationale, design, and baseline characteristics of the CArdiovascular safety and Renal Microvascular outcomE study with LINAgliptin (CARMELINA(®)): a randomized, double-blind, placebo-controlled clinical trial in patients with type 2 diabetes and high cardio-renal risk
  12. 47832
    “…Although computer-delivered interventions are well poised to surmount key barriers to the treatment of social anxiety, most are only marginally effective when delivered as stand-alone treatments. …”
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    Evaluating a Web-Based Social Anxiety Intervention Among University Students: Randomized Controlled Trial
  13. 47833
    “…Using the S-TOFHLA, 81% of the schizophrenia group had adequate HL; 6% were marginal and 13% were inadequate. In contrast, 97% of the non-schizophrenia group had adequate HL. …”
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    T60. HEALTH LITERACY IN PEOPLE WITH SCHIZOPHRENIA ATTENDING COMMUNITY MENTAL HEALTH CLINICS
  14. 47834
    “…An average 0.59-point reduction in HbA1c was observed from baseline to the end of the 16-week active intervention (t=1.99, DF=17, p=0.063). A marginally significant weight reduction was observed from baseline to week 16 in the active condition of 5.3 pounds (t=2.07, DF=17, p=0.054). …”
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    S94. INTEGRATED DIABETES MANAGEMENT FOR INDIVIDUALS WITH SERIOUS MENTAL ILLNESS
  15. 47835
    “…There was no significant difference in the probability of being employed between HIV-positive participants with CD4>500 and the reference group of HIV-negative participants residing in households with no HIV-positive adults (marginal effect, ME, 1.49 percentage points; 95% confidence interval, CI, -1.09, 4.08). …”
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    High CD4 counts associated with better economic outcomes for HIV-positive adults and their HIV-negative household members in the SEARCH Trial
  16. 47836
    “…ACR included “loop-around” suture fixation using two side-to-side sutures and an anchor at the articular margin in order to restore anatomy and secure the tendon along the anterior edge of the cuff defect. …”
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    Anterior Cable Reconstruction Using the Proximal Biceps Tendon for Large Rotator Cuff Defects Limits Superior Migration and Subacromial Contact Without Restricting Range of Motion
  17. 47837
    “…Three-dimensional spoiled gradient-echo sequence (3D-SPGR) MRI was performed for all hips, and the presence of ONFH was determined by finding the area surrounded by the outer margin of the low-signal-intensity band on 3D-SPGR MRI. …”
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    Which Classification System Is Most Useful for Classifying Osteonecrosis of the Femoral Head?
  18. 47838
    “…When smokers were included in analyses, results for most causes of death were broadly similar, although marginally stronger associations were seen among people with lower BMI, suggesting slight residual confounding by smoking. …”
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    Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK
  19. 47839
    “…In simulated patients with varying CLcr who received these regimens, high percent probabilities of PK-PD target attainment were achieved for KP, PA and SA at the upper margins of the MIC distributions (Figures 1–3). [Image: see text] [Image: see text] [Image: see text] CONCLUSION: The data provide support for ME1100 dose selection for patients with HABP/VAPB. …”
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    1392. Pharmacokinetic-Pharmacodynamic (PK-PD) Target Attainment Analyses to Support Inhaled ME1100 Dose Selection
  20. 47840
    “…To determine if women were willing to make a trade-off for higher pregnancy rates at the expense of a higher burden, we calculated the marginal rate of substitution. MAIN RESULTS AND THE ROLE OF CHANCE: The questionnaire was completed by 145 women. …”
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    Women’s perspectives on ovulation induction with or without IUI as treatment for normogonadotrophic anovulation: a discrete choice experiment
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