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  1. 47841
    “…The primary endpoint was the adenoma detection rate (ADR; the proportion of participants with any adenoma) at 1 year surveillance colonoscopy analysed in all participants with observable follow-up data using a so-called at-the-margins approach, adjusted for BCSP site and repeat endoscopy at baseline. …”
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  2. 47842
  3. 47843
    “…The mean change in telomerase activity from baseline was marginally significant in the intervention group (effect size [d], 0.13; 95% CI, 0.001-0.27) but not in the wait-list control group (d, −0.03; 95% CI, −0.16 to 0.10). …”
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  4. 47844
    “…Confirmatory testing was based on the TPol estimand; within each dose level, non-inferiority for the primary endpoint (non-inferiority margin: 0.3%) had to be confirmed before testing superiority for the primary and confirmatory secondary endpoints. …”
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  5. 47845
    “…We fitted design-based linear and quadratic logistic regression models and estimated the annual rate of changes in modern contraceptive prevalence rates for each country setting from the average marginal effects of the fitted models (expressed in absolute percentage points). …”
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  6. 47846
    “…Primary outcome analyses included only participants who had follow-up data, irrespective of the baseline visit N gonorrhoeae test result. The margin used to establish non-inferiority was a lower confidence limit of 5% for the risk difference. …”
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  7. 47847
    “…A mean difference of 0.0 g/kg/day was expected, with a non-inferiority margin fixed at −0.5 g/kg/day. Linear and logistic mixed regression analyses were performed, with study site and team as random effects. …”
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  8. 47848
  9. 47849
    “…Currently available F508del therapeutics only marginally improve CF, In vitro, we have identified a miRNA that impairs utility of CFTR directed therapies. miR-145 is upregulated by TGF-β (a genetic modifier of CF lung disease) with a direct binding site on the 3’-untranslated region of CFTR mRNA. …”
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  10. 47850
    “…For the primary aim, the adjusted least square mean (SD) xerostomia score in the TA group (26.6 [17.7]) was significantly lower than in the SCC group (34.8 [18.7]) (P = .001; effect size = −0.44) and marginally lower but not statistically significant different from the SA group (31.3 [18.6]) (P = .06; effect size = −0.26). …”
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  11. 47851
    “…However, the transfibular neck osteotomy approach is more suitable for the posterolateral plateau articular surface damaged with bone separation and displacement, deep collapse, cases involving a large range of the posterolateral column, especially fractures of the lateral tibial plateau in the upper tibiofibular syndesmosis area of the line connecting the anterior and posterior margin of the fibular head to the midpoint of the plateau.…”
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  12. 47852
    “…It is highly desirable that a civil marine core not use soluble boron for reactivity control, but it is then a challenge to achieve an adequate shutdown margin throughout the core life while maintaining reactivity control and acceptable power distributions in the core. …”
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  13. 47853
  14. 47854
    “…The variation of LoS across calendar years was marginal for both vaginal delivery modes (VDM). The adjusted mean LoS was higher in IVD than SVD, and although a decline of LoS > ED and mean LoS over time was observed for both VDM, there was little variation of the adjusted mean LoS by nationality of the woman and by level of pregnancy risk (high vs. low). …”
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  15. 47855
    “…The amounts of charged fibers in a filter were increased to achieve high efficiency of 90% for the virus filter but the electrical interference between neighbouring fibers resulted in progressively marginal increase in efficiency yet much higher pressure drop across the filter. …”
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  16. 47856
  17. 47857
    “…However, at 18 months, mean weight loss was 4.3±1.7 kg in those in the very poor category and 8.2±1.2 kg in those in the poor or better category, with a marginally significant between-group difference (p=0.07). …”
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  18. 47858
    “…However, we would recommend repeating IGF-1 levels at 3–6 months in those who have marginally elevated IGF-1 above normal (≤ 1.12), without cavernous sinus invasion and a post-operative GH of <1 ng/mL prior to intervening if the IGF-1 is elevated 6 weeks as the IGF-1 may normalize.…”
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  19. 47859
  20. 47860
    “…Convergent validity against BPRS was moderate for both rater-administered (r=0.65 (0.55–0.73); Marginal Maximum Likelihood Estimation (MMLE)=0.052, Standard Error (SE)=0.005, p<0.00001) and self-administered (r=0.66; MMLE=0.057, SE=0.005, p<0.00001) versions. …”
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