“…It is advisable to select patients appropriately, including only those with the thoracic or lumbar spine involvement and keeping at least 2 mm separation between the target and the cord/cauda. More margin is needed if the distance between the isocenter and cord/cauda is larger. …”
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“…With the high-titre group as the active control group, we did a non-inferiority analysis of the proportion of participants with IgA seroconversion in the mid-titre and low-titre groups, using a non-inferiority margin of less than 20%. This trial is registered at ClinicalTrials.gov (NCT03483116). …”
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“…However, after performing a multiple logistic regression analysis, osteoarthritis was not found to be an independent predictor of re-tear. There were very marginal differences in patient-reported outcomes at 6-months after surgery between the two groups (Table 1). …”
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“…Vaccine coverage (three mRNA doses vs none) was 9307 (94·2%) of 9878 among BA.5 cases and 30 581 (94·8%) of 32 272 among BA.2 cases, although in the adjusted analysis, there was a trend towards slightly higher vaccination coverage among BA.5 cases than BA.2 cases (OR 1·18 [95% CI 0·99–1·42]; p=0·064), possibly suggesting marginally poorer vaccine protection against BA.5. The rate of hospitalisation due to COVID-19 was higher among the BA.5 cases (210 [1·9%] of 11 314) than among the BA.2 cases (514 [1·4%] of 36 805), with an OR of 1·34 (95% CI 1·14–1·57) and an adjusted OR of 1·69 (95% CI 1·22–2·33), despite low and stable COVID-19 hospitalisation numbers during the study period. …”
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“…Reported abuse in the respondents’ organizations was relatively low (1.81), while among women managers marginally less than their male equivalents (in absolute value, the mean difference in the mean scores fell between 0.28 and 1.25). …”
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“…[Figure: see text] METHODS: E-2 and -3 were global Phase 3, parallel-group, double-blind, noninferiority (10% margin) RCTs comparing the efficacy and safety of oral gepotidacin (1500mg BID, 5 days) vs NTF (100mg BID, 5 days) in female patients (≥ 12 years) with uUTI. …”
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“…Avicularia synapomorphies are juveniles bearing black tarsi contrasting with other lighter articles; spermathecae with an accentuated outwards curvature medially, and male palpal bulb with embolus medial portion and tegulum’s margin form an acute angle in retrolateral view. Avicularia is composed of twelve species, including three new species: Avicularia avicularia (Linnaeus, 1818), Avicularia glauca Simon, 1891, Avicularia variegata (F. …”
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“…Two months after cessation of methotrexate he remains asymptomatic, with marginally elevated ferritin but otherwise normal routine bloods. …”
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“…Although there was a marginal decrease of PCS and PPCS crudes rates over time in the whole region, accompained by a progressive enhancement of the crude VBAC rate, we found remarkable variability of DM across hospitals. …”
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“…On univariate analysis, factors significantly associated with metastasis-free survival were the first postoperative PSA (HR 1.07, 95% CI 1.03–1.12, p = 0.002), seminal vesicle involvement (HR 3.48, 95% CI 1.26–9.6,p = 0.02), extracapsular extension (HR 7.02, 95% CI 1.96–25.07, p = 0.003), and surgical margin status (HR 2.86, 95% CI 1.03–7.97, p = 0.04). …”
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“…In BLSA, we found that CA and CDCA were detectable in postmortem brain tissue samples and were marginally higher in AD samples compared to CON. In ROSMAP, we found sex-specific differences in altered neuronal gene expression of BA receptors in AD. …”
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“…Twenty-two pts had a HM: plasma cell dyscrasia (n=7, 31.8%; multiple myeloma n=6, MGUS n=1), chronic lymphocytic leukemia (n=3, 13.6%), chronic myelomonocytic leukemia (n=2, 9.1%), diffuse large B-cell lymphoma (n=2, 9.1%), hodgkin’s lymphoma (n=2, 9.1%), and one patient (4.5%) with each of the following malignancies: acute promyelocytic leukemia, anaplastic large cell lymphoma, B-cell lymphoma not otherwise specified, follicular lymphoma, mantle cell lymphoma and marginal zone lymphoma. With respect to HM treatment status, the majority of the patients were in surveillance (n=14, 63.6%); the other eight (36.4%) were on active treatment at time of COVID-19 infection. …”
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“…Gait speed, MoCA score, fasting glucose, HbA1c and tMFR were significantly associated with adverse outcomes, and the effects of aMFR were marginal (P = 0.074). CONCLUSIONS: Older adults identified with low MFR had unfavourable body composition, poor functional performance, high cardiometabolic risk and a high risk for the clinical outcome.…”
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“…Histopathology at this time was consistent with extranodal marginal zone lymphoma (EMZL) of MALT (mucosa-associated lymphoid tissue) type, IgG4 positive. …”
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“…With the higher and higher development level of psychological capital, the impact of relative income on psychological capital gradually weakens or even disappears, and the marginal impact of relative income shows a downward trend. …”
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“…The primary endpoint was the proportion of participants (pts) with CMV disease adjudicated by blinded committee through Week 52 post-KT (non-inferiority margin,10%). RESULTS: A total of 601 pts were randomized; 589 received ≥ 1 dose of study medication (median age [range], 51 [18–82] years; male, 72%; Black/African American, 9%; deceased donor, 60%; received lymphocyte-depleting induction immunosuppression, 46%), of whom two had detectable CMV viral DNA on Day 1 and one was CMV R+ (full analysis set, 586 pts). …”
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“…Unfortunately, the cyclophosphamide could not be continued as he developed gastrointestinal side effects and the combination only conferred marginal benefit. Blood tests done 6 months following rituximab did show a depletion in his B cell count from 294 to 0, and in his RF from 864 to 276. …”
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“…Noninferiority was assessed through 95.002% confidence intervals (CI) using a margin of 4%. Secondary endpoints included proportion with HIV-1 RNA <50 c/mL and safety measures at W48. …”
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“…The PTV included the ITV plus 5 mm uniform margin applied to the ITV. The PTV ranged from 11.1 to 163.0 cc ([Formula: see text]). …”
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“…Efficacy was assessed at the W24 (1(○) endpoint, noninferiority margin 6%) and at W48 as the proportion with HIV-1 RNA ≥ 50 c/mL by FDA Snapshot and by changes in CD4 count. …”
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