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  1. 48041
    “…Diagnoses include CLL (5), marginal zone lymphoma (MZL; 4), diffuse large B-cell lymphoma (3), follicular lymphoma (1), mantle cell lymphoma (MCL;4), and Waldenstrom's macroglobulinemia (1). …”
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    Antibody and T-Cell Responses to Covid-19 mRNA Vaccines in Patients with B-Cell Lymphomas and Chronic Lymphocytic Leukemia (CLL)
  2. 48042
    “…Characteristics and outcomes are summarized in Table 1. ST patients were marginally older than HM patients (p<0.025). A significantly greater proportion of HM patients were male (p<0.0023). …”
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    Four-Fold Increased Mortality from Sars-Cov-2 Infection in Patients with Hematologic Versus Non-Hematologic Malignancies Treated at the Largest Tertiary COVID-19 Center in Chicago/Rush University Medical Center (March 1, 2020-December 31,2020)
  3. 48043
    “…The prevalence of confirmed SARS-CoV-2 infection in this cohort (14.5%) is marginally higher than reported in the US population (10.5%) but statistical comparisons were not performed given that this study does not provide a general epidemiological estimate. …”
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    Safety and Tolerability of Sars-Cov-2 Vaccination and Natural History of Infection Among Patients with Castleman Disease
  4. 48044
    “…Given the pre-defined margin of −2%, statistically significant non-inferiority of HyFoSy relative to HSG could not be demonstrated (P = 0.27). …”
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    Can hysterosalpingo-foam sonography replace hysterosalpingography as first-choice tubal patency test? A randomized non-inferiority trial
  5. 48045
    “…Adherence to TB medication was comparable between the intervention arm [geometric mean percentage (GM%) 99.01%, geometric standard deviation (GSD) 1.02] and the control arm [GM% 98.97%, GSD 1.04] and was within the prespecified margin for non-inferiority [mean ratio (MR) 1.00 (95% CI 0.99–1.01); p = 0.954]. …”
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    Effectiveness of a digital medication event reminder and monitor device for patients with tuberculosis (SELFTB): a multicenter randomized controlled trial
  6. 48046
    “…A further rheumatology review helped to re-evaluate the clinical condition, indicating tenderness over left T4 and T5 paraspinal region along with left anterior rib margin tenderness. Further CT and MRI imaging, specialist musculoskeletal radiologist review and multidisciplinary team input revealed costovertebral arthritis secondary to lupus causing back pain and referred pain to chest wall. …”
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    P46 A rare case of costovertebral arthritis in SLE
  7. 48047
    “…However, comparing an investigational drug to budesonide is statistically infeasible: powering a non-inferiority study against a budesonide comparator arm with 90% power for a 10% non-inferiority margin would require over 700 subjects, yet fewer than 400 patients have been randomized in all historical MC trials. …”
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    A180 PLACEBO RATES IN MICROSCOPIC COLITIS RANDOMIZED TRIALS: APPLICATIONS FOR FUTURE DRUG DEVELOPMENT USING A HISTORICAL CONTROL ARM
  8. 48048
    “…Noninferiority was assessed with 95% confidence intervals (CI) (12% margin). Other secondary endpoints were safety (adverse events [AEs], laboratory abnormalities) and predefined analyses of bone mineral density (BMD) and measures of renal function (eGFR, proteinuria). …”
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    LB4. A Phase 3, Randomized, Controlled Clinical Trial of Bictegravir in a Fixed-Dose Combination, B/F/TAF, vs. ABC/DTG/3TC in Treatment-Naïve Adults at Week 96
  9. 48049
    “…RESULTS: We outline seven propositions that call for further research attention: public procurement, as regulated in the European Union, is not suitable for addiction treatment; marketization challenges democracy, equity, needs assessment, and treatment planning; marketization causes new accountability problems and idle monitoring; marketization causes fragmentation and obstructs coordination and continuity of care; marketization causes unification of services and favors big bureaucratically sophisticated providers; treatment professionals’ values are downplayed when a mistrust-based market logic replaces a trust- and needs-based logic; and marketization marginalizes treatment professionals and service users by limiting discretion. …”
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    Why Research Should Pay Attention to Effects of Marketization of Addiction Treatment Systems
  10. 48050
    “…Summary sensitivity for the Xpert Xpress assay (99.4%, 95% CI 98.0% to 99.8%) was 22.6 (95% CI 18.8 to 26.3) percentage points higher than that of ID NOW (76.8%, (95% CI 72.9% to 80.3%), whilst the specificity of Xpert Xpress (96.8%, 95% CI 90.6% to 99.0%) was marginally lower than ID NOW (99.6%, 95% CI 98.4% to 99.9%; a difference of −2.8% (95% CI −6.4 to 0.8)) AUTHORS' CONCLUSIONS: This review identifies early‐stage evaluations of point‐of‐care tests for detecting SARS‐CoV‐2 infection, largely based on remnant laboratory samples. …”
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    Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection
  11. 48051
    “…METHODS: A retrospective analysis of prospectively collected data from a single tertiary academic medical center of consecutive patients undergoing surgical treatment for massive irreparable RCT without arthritis using SCR, PR (using interval slide and/or margin convergence), or rTSA from 01/01/2006 to 01/01/2018 was performed. …”
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    Treatment of Massive Irreparable Rotator Cuff Tears without Arthritis: A Comparison of Superior Capsular Reconstruction, Partial Rotator Cuff Repair, and Reverse Total Shoulder Arthroplasty (228)
  12. 48052
    por Winn, W. A., Petroff, S. A.
    Publicado 1933
    “…The microscopic lesions, 2 weeks after inoculation, were composed of irregularly shaped clumps of necrosing large mononuclear cells. The margins were clear-cut and bordered by few or no lymphocytic cells. …”
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    BIOLOGICAL STUDIES OF THE TUBERCLE BACILLUS : II. A NEW CONCEPTION OF THE PATHOLOGY OF EXPERIMENTAL AVIAN TUBERCULOSIS WITH SPECIAL REFERENCE TO THE DISEASE PRODUCED BY DISSOCIATED VARIANTS
  13. 48053
    por Singh, Ajai R., Singh, Shakuntala A.
    Publicado 2007
    “…And there are massive profit margins to be maintained. If these were to be dependent only on genuine drug discoveries, that would be taking too great a risk. 2. …”
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    Guidelines, Editors, Pharma And The Biological Paradigm Shift
  14. 48054
    “…The majority of species can be recognized by the presence of a distinct stria or sulcus along the apical margin of the pygidium, though it is not exclusive to the genus. …”
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    A systematic revision of Operclipygus Marseul (Coleoptera, Histeridae, Exosternini)
  15. 48055
    “…Primary as-randomized results (Table, Figure) exceeded the non-inferiority margin in favor of mupirocin, for S. aureus clinical cultures (21% superiority, P< 0.001) and for MRSA clinical cultures (20% superiority, P< 0.001). …”
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    4. 137 Hospital Cluster-Randomized Trial of Mupirocin-Chlorhexidine vs Iodophor-Chlorhexidine for Universal Decolonization in Intensive Care Units (ICUs) (Mupirocin Iodophor Swap Out Trial)
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