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  1. 135961
    “…METHODS: This was a retrospective case–control study including 31 health systems in the United States from the National COVID Cohort Collaborative (N3C). 8,325 individuals with PASC (defined by the presence of the International Classification of Diseases, version 10 code U09.9 or a long-COVID clinic visit) matched to 41,625 controls within the same health system and COVID index date within ± 45 days of the corresponding case's earliest COVID index date. …”
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    Risk factors associated with post-acute sequelae of SARS-CoV-2: an N3C and NIH RECOVER study
  2. 135962
    por Whelan, Christopher D, Altmann, Andre, Botía, Juan A, Jahanshad, Neda, Hibar, Derrek P, Absil, Julie, Alhusaini, Saud, Alvim, Marina K M, Auvinen, Pia, Bartolini, Emanuele, Bergo, Felipe P G, Bernardes, Tauana, Blackmon, Karen, Braga, Barbara, Caligiuri, Maria Eugenia, Calvo, Anna, Carr, Sarah J, Chen, Jian, Chen, Shuai, Cherubini, Andrea, David, Philippe, Domin, Martin, Foley, Sonya, França, Wendy, Haaker, Gerrit, Isaev, Dmitry, Keller, Simon S, Kotikalapudi, Raviteja, Kowalczyk, Magdalena A, Kuzniecky, Ruben, Langner, Soenke, Lenge, Matteo, Leyden, Kelly M, Liu, Min, Loi, Richard Q, Martin, Pascal, Mascalchi, Mario, Morita, Marcia E, Pariente, Jose C, Rodríguez-Cruces, Raul, Rummel, Christian, Saavalainen, Taavi, Semmelroch, Mira K, Severino, Mariasavina, Thomas, Rhys H, Tondelli, Manuela, Tortora, Domenico, Vaudano, Anna Elisabetta, Vivash, Lucy, von Podewils, Felix, Wagner, Jan, Weber, Bernd, Yao, Yi, Yasuda, Clarissa L, Zhang, Guohao, Bargalló, Nuria, Bender, Benjamin, Bernasconi, Neda, Bernasconi, Andrea, Bernhardt, Boris C, Blümcke, Ingmar, Carlson, Chad, Cavalleri, Gianpiero L, Cendes, Fernando, Concha, Luis, Delanty, Norman, Depondt, Chantal, Devinsky, Orrin, Doherty, Colin P, Focke, Niels K, Gambardella, Antonio, Guerrini, Renzo, Hamandi, Khalid, Jackson, Graeme D, Kälviäinen, Reetta, Kochunov, Peter, Kwan, Patrick, Labate, Angelo, McDonald, Carrie R, Meletti, Stefano, O'Brien, Terence J, Ourselin, Sebastien, Richardson, Mark P, Striano, Pasquale, Thesen, Thomas, Wiest, Roland, Zhang, Junsong, Vezzani, Annamaria, Ryten, Mina, Thompson, Paul M, Sisodiya, Sanjay M
    Publicado 2018
    “…Structural brain measures were extracted from MRI brain scans across 2149 individuals with epilepsy, divided into four epilepsy subgroups including idiopathic generalized epilepsies (n =367), mesial temporal lobe epilepsies with hippocampal sclerosis (MTLE; left, n = 415; right, n = 339), and all other epilepsies in aggregate (n = 1026), and compared to 1727 matched healthy controls. We ranked brain structures in order of greatest differences between patients and controls, by meta-analysing effect sizes across 16 subcortical and 68 cortical brain regions. …”
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    Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study
  3. 135963
    por Palmer, Suetonia C, Tendal, Britta, Mustafa, Reem A, Vandvik, Per Olav, Li, Sheyu, Hao, Qiukui, Tunnicliffe, David, Ruospo, Marinella, Natale, Patrizia, Saglimbene, Valeria, Nicolucci, Antonio, Johnson, David W, Tonelli, Marcello, Rossi, Maria Chiara, Badve, Sunil V, Cho, Yeoungjee, Nadeau-Fredette, Annie-Claire, Burke, Michael, Faruque, Labib I, Lloyd, Anita, Ahmad, Nasreen, Liu, Yuanchen, Tiv, Sophanny, Millard, Tanya, Gagliardi, Lucia, Kolanu, Nithin, Barmanray, Rahul D, McMorrow, Rita, Raygoza Cortez, Ana Karina, White, Heath, Chen, Xiangyang, Zhou, Xu, Liu, Jiali, Rodríguez, Andrea Flores, González-Colmenero, Alejandro Díaz, Wang, Yang, Li, Ling, Sutanto, Surya, Solis, Ricardo Cesar, Díaz González-Colmenero, Fernando, Rodriguez-Gutierrez, René, Walsh, Michael, Guyatt, Gordon, Strippoli, Giovanni F M
    Publicado 2021
    “…The absolute benefits of these drugs vary substantially across patients from low to very high risk of cardiovascular and renal outcomes (eg, SGLT-2 inhibitors resulted in 3 to 40 fewer deaths in 1000 patients over five years; see interactive decision support tool (https://magicevidence.org/match-it/200820dist/#!/) for all outcomes. CONCLUSIONS: In patients with type 2 diabetes, SGLT-2 inhibitors and GLP-1 receptor agonists reduced cardiovascular and renal outcomes, with some differences in benefits and harms. …”
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    Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials
  4. 135964
    “…We discuss lessons learned from calibration and suggest tactical strategies that will optimize the quality of science data acquired during operation at Mars. While most results matched expectations, some surprises were discovered, such as a strong wavelength and temperature dependence on the radiometric coefficients and a scene-dependent dynamic component to the zero-exposure bias frames. …”
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    Pre-Flight Calibration of the Mars 2020 Rover Mastcam Zoom (Mastcam-Z) Multispectral, Stereoscopic Imager
  5. 135965
    “…BACKGROUND: Although effective mental health treatments exist, the ability to match individuals to optimal treatments is poor, and timely assessment of response is difficult. …”
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    Toward a Mobile Platform for Real-world Digital Measurement of Depression: User-Centered Design, Data Quality, and Behavioral and Clinical Modeling
  6. 135966
    “…METHODS: In this controlled non-randomized trial, 81 consecutive prospectively enrolled patients with COVID-19 pneumonia and moderate-to-severe (paO2/FiO2 ratio < 200) acute hypoxemic respiratory failure treated with early PP + NIV during Dec 2020–May 2021were compared with 162 consecutive patients with COVID-19 pneumonia matched for age, mortality risk, severity of illness and paO2/FiO2 ratio at admission, treated with conventional (supine) NIV during Apr 2020–Dec 2020 at HUMANITAS Gradenigo Subintensive Care Unit, after propensity score adjustment for multiple baseline and treatment-related variables to limit confounding. …”
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    Early prolonged prone position in noninvasively ventilated patients with SARS-CoV-2-related moderate-to-severe hypoxemic respiratory failure: clinical outcomes and mechanisms for treatment response in the PRO-NIV study
  7. 135967
    por Katzdobler, Sabrina, Nitschmann, Alexander, Barthel, Henryk, Bischof, Gerard, Beyer, Leonie, Marek, Ken, Song, Mengmeng, Wagemann, Olivia, Palleis, Carla, Weidinger, Endy, Nack, Anne, Fietzek, Urban, Kurz, Carolin, Häckert, Jan, Stapf, Theresa, Ferschmann, Christian, Scheifele, Maximilian, Eckenweber, Florian, Biechele, Gloria, Franzmeier, Nicolai, Dewenter, Anna, Schönecker, Sonja, Saur, Dorothee, Schroeter, Matthias L., Rumpf, Jost-Julian, Rullmann, Michael, Schildan, Andreas, Patt, Marianne, Stephens, Andrew W., van Eimeren, Thilo, Neumaier, Bernd, Drzezga, Alexander, Danek, Adrian, Classen, Joseph, Bürger, Katharina, Janowitz, Daniel, Rauchmann, Boris-Stephan, Stöcklein, Sophia, Perneczky, Robert, Schöberl, Florian, Zwergal, Andreas, Höglinger, Günter U., Bartenstein, Peter, Villemagne, Victor, Seibyl, John, Sabri, Osama, Levin, Johannes, Brendel, Matthias
    Publicado 2022
    “…METHODS: Seventy-eight patients with 4RTs (71 ± 7 years, 39 female), 79 patients with other neurodegenerative diseases (67 ± 12 years, 35 female) and twelve age-matched controls (69 ± 8 years, 8 female) underwent dynamic (0–60 min) [(18)F]PI-2620 PET imaging. …”
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    Additive value of [(18)F]PI-2620 perfusion imaging in progressive supranuclear palsy and corticobasal syndrome
  8. 135968
    “…At an early (4-month-old) disease stage, hemizygous 5xFAD/homozygous Trem2(R47H NSS) (5xFAD/Trem2(R47H NSS)) mice have reduced size and number of microglia that display impaired interaction with plaques compared to microglia in age-matched 5xFAD hemizygous controls. This is associated with a suppressed inflammatory response but increased dystrophic neurites and axonal damage as measured by plasma neurofilament light chain (NfL) level. …”
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    A Trem2(R47H) mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques
  9. 135969
    “…Protein expression of BTN2A1 and BTN3A1, along with gene expression related to lipid metabolism and glioma inflammatory response pathways, is analyzed in matched tumor tissue samples. Additionally, the study explores two strategies to re-sensitize tumors in the weak anti-tumor effect (WAT) group: utilizing a BTN3A1 agonistic antibody or employing bisphosphonates to inhibit farnesyl diphosphate synthase (FPPS). …”
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    B7H3-targeting chimeric antigen receptor modification enhances antitumor effect of Vγ9Vδ2 T cells in glioblastoma
  10. 135970
    por Stirnemann, J., Villar, J., Salomon, L. J., Ohuma, E., Ruyan, P., Altman, D. G., Nosten, F., Craik, R., Munim, S., Cheikh Ismail, L., Barros, F. C., Lambert, A., Norris, S., Carvalho, M., Jaffer, Y. A., Noble, J. A., Bertino, E., Gravett, M. G., Purwar, M., Victora, C. G., Uauy, R., Bhutta, Z., Kennedy, S., Papageorghiou, A. T., Katz, M, Bhan, MK, Garza, C, Zaidi, S, Langer, A, Rothwell, PM, Weatherall, Sir D, Bhutta, ZA, Villar, J, Kennedy, S, Altman, DG, Barros, FC, Bertino, E, Burton, F, Carvalho, M, Ismail, L Cheikh, Chumlea, WC, Gravett, MG, Jaffer, YA, Lambert, A, Lumbiganon, P, Noble, JA, Pang, RY, Papageorghiou, AT, Purwar, M, Rivera, J, Victora, C, Uauy, R, Kennedy, S, Villar, J, Altman, DG, Barros, FC, Berkley, J, Burton, F, Carvalho, M, Ismail, L Cheikh, Chumlea, WC, Lambert, A, Munim, S, Norris, S, Nosten, F, Papageorghiou, AT, Victora, C, Villar, J, Altman, DG, Ismail, L Cheikh, Kennedy, S, Lambert, A, Noble, JA, Papageorghiou, AT, Bhutta, ZA, Craik, R, Uauy, R, Villar, J, Ismail, L Cheikh, Kennedy, S, Lambert, A, Papageorghiou, AT, Shorten, M, Hoch, L, Knight, HE, Ohuma, EO, Cosgrove, C, Blakey, I, Ash, S, Craik, R, Altman, DG, Ohuma, EO, Urias, E Staines, Villar, J, Altman, DG, Roseman, F, Kunnawar, N, Gu, SH, Wang, JH, Wu, MH, Domingues, M, Gilli, P, Juodvirsiene, L, Hoch, L, Musee, N, Al‐Jabri, H, Waller, S, Cosgrove, C, Muninzwa, D, Ohuma, EO, Yellappan, D, Carter, A, Reade, D, Miller, R, Ahmed, I, Ash, S, Condon, C, Mainwaring, M, Muninzwa, D, da Silveira, MF, Urias, E Staines, Walusuna, L, Wiladphaingern, S, Papageorghiou, AT, Salomon, L, Leston, A, Mitidieri, A, Al‐Aamri, F, Paulsene, W, Sande, J, Al‐Zadjali, WKS, Batiuk, C, Bornemeier, S, Carvalho, M, Dighe, M, Gaglioti, P, Jacinta, N, Jaiswal, S, Noble, JA, Oas, K, Oberto, M, Olearo, E, Owende, MG, Shah, J, Sohoni, S, Todros, T, Venkataraman, M, Vinayak, S, Wang, L, Wilson, D, Wu, QQ, Zaidi, S, Zhang, Y, Chamberlain, P, Danelon, D, Sarris, I, Dhami, J, Ioannou, C, Knight, CL, Napolitano, R, Wanyonyi, S, Pace, C, Mkrtychyan, V, Buckle, M, Jackson, N, Mitidieri, A, Munim, S, Mwangudzah, H, Norris, T, Shah, J, Zainab, G, Ismail, L Cheikh, Chumlea, WC, Al‐Habsi, F, Bhutta, ZA, Carter, A, Alija, M, Jimenez‐Bustos, JM, Kizidio, J, Puglia, F, Kunnawar, N, Liu, H, Lloyd, S, Mota, D, Ochieng, R, Rossi, C, Luna, M Sanchez, Shen, YJ, Knight, HE, Rocco, DA, Frederick, IO, Kizidio, J, Monyepote, B, Salim, M, Salam, R, Carrara, VI, Craik, R, Alam, D, Guman, Y, Kilonzo, J, Min, A, Ngami, V, Olivera, I, Deutsch, G, Bhutta, ZA, Albernaz, E, Batra, M, Bhat, BA, Bertino, E, Nicola, P Di, Giuliani, F, Rovelli, I, McCormick, K, Ochieng, R, Pang, RY, Paul, V, Rajan, V, Wilkinson, A, Uauy, R, Varalda, A, Eskenazi, B, Bradman, A, Burnham, O, Corra, LA, Dolk, H, Farhi, F, Finkton, D, Golding, J, Matijasevich, A, de Wet, T, Villar, J, Zhang, JJ, Stein, A, Fernandes, M, Abubakar, A, Acedo, J, Aranzeta, L, Ismail, L Cheikh, Giuliani, F, Ibanez, D, Kennedy, S, Kihara, M, de Leon, E, Newton, CR, Savini, S, Soria‐Frisch, A, Villar, J, Wulff, K, Barros, FC, Domingues, M, Fonseca, S, Leston, A, Mitidieri, A, Mota, D, Sclowitz, IK, da Silveira, MF, Pang, RY, He, YP, Pan, Y, Shen, YJ, Wu, MH, Wu, QQ, Wang, JH, Yuan, Y, Zhang, Y, Purwar, M, Choudhary, A, Choudhary, S, Deshmukh, S, Dongaonkar, D, Ketkar, M, Khedikar, V, Kunnawar, N, Mahorkar, C, Mulik, I, Saboo, K, Shembekar, C, Singh, A, Taori, V, Tayade, K, Somani, A, Bertino, E, Nicola, P Di, Frigerio, M, Gilli, G, Gilli, P, Giolito, M, Giuliani, F, Oberto, M, Occhi, L, Rossi, C, Rovelli, I, Signorile, F, Todros, T, Stones, W, Carvalho, M, Kizidio, J, Ochieng, R, Shah, J, Vinayak, S, Musee, N, Kisiang'ani, C, Muninzwa, D, Kilonzo, J, Sande, J, Berkley, J, Kemp, B, Barsosio, H, Mwakio, S, Mwangudzah, H, Ngami, V, Salim, M, Seale, A, Walusuna, L, Jaffer, YA, Al‐Abri, J, Al‐Abduwani, J, Al‐Habsi, FM, Al‐Lawatiya, H, Al‐Rashidiya, B, Al‐Zadjali, WKS, Juangco, FR, Venkataraman, M, Al‐Jabri, H, Yellappan, D, Munim, S, Zainab, G, Ahmed, I, Alam, D, Raza, A, Salam, R, Norris, S, Guman, Y, Lephoto, T, Macauley, S, Malgas, L, Nosten, F, Jackson, N, McGready, R, Min, A, Cararra, VI, Wiladphaingern, S, Kennedy, S, Ismail, L Cheikh, Lambert, A, Lloyd, S, Napolitano, R, Ohuma, EO, Papageorghiou, AT, Patel, B, Puglia, F, Roseman, F, Roseman, S, Ioannou, C, Sarris, I, Ash, S, Baricco, M, Capp, A, Craik, R, Hussein, S, Laister, A, Lewis, T, Maggiora, E, Norris, T, Sharps, M, Varalda, A, Carew, R, Gravett, MG, Batiuk, C, Batra, M, Bornemeier, S, Dighe, M, Oas, K, Paulsene, W, Wilson, D, Frederick, IO, Andersen, HF, Abbott, SE, Carter, AA, Algren, H, Rocco, DA, Sorensen, TK, Enquobahrie, D, Waller, S
    Publicado 2017
    “…At term, the EFW centiles matched those of the INTERGROWTH‐21(st) Newborn Size Standards but, at < 37 weeks' gestation, the EFW centiles were, as expected, higher than those of babies born preterm. …”
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    International estimated fetal weight standards of the INTERGROWTH‐21(st) Project
  11. 135971
    por Koivula, Robert W., Forgie, Ian M., Kurbasic, Azra, Viñuela, Ana, Heggie, Alison, Giordano, Giuseppe N., Hansen, Tue H., Hudson, Michelle, Koopman, Anitra D. M., Rutters, Femke, Siloaho, Maritta, Allin, Kristine H., Brage, Søren, Brorsson, Caroline A., Dawed, Adem Y., De Masi, Federico, Groves, Christopher J., Kokkola, Tarja, Mahajan, Anubha, Perry, Mandy H., Rauh, Simone P., Ridderstråle, Martin, Teare, Harriet J. A., Thomas, E. Louise, Tura, Andrea, Vestergaard, Henrik, White, Tom, Adamski, Jerzy, Bell, Jimmy D., Beulens, Joline W., Brunak, Søren, Dermitzakis, Emmanouil T., Froguel, Philippe, Frost, Gary, Gupta, Ramneek, Hansen, Torben, Hattersley, Andrew, Jablonka, Bernd, Kaye, Jane, Laakso, Markku, McDonald, Timothy J., Pedersen, Oluf, Schwenk, Jochen M., Pavo, Imre, Mari, Andrea, McCarthy, Mark I., Ruetten, Hartmut, Walker, Mark, Pearson, Ewan, Franks, Paul W.
    Publicado 2019
    “…The cohorts were studied in parallel using matched protocols across seven clinical centres in northern Europe. …”
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    Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium
  12. 135972
    “…METHODS: We enrolled 98 COVID-19 patients with varying disease severity (3 asymptomatic, 53 mild, 34 moderate, 5 severe, 3 critical) and 78 non-COVID-19 controls matched for gender and co-morbidities. All subjects had fecal specimens sampled at inclusion. …”
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    Temporal landscape of human gut RNA and DNA virome in SARS-CoV-2 infection and severity
  13. 135973
    “…A total of 142 patients with VCFs aged over 60 years old and 108 age-matched asymptomatic controls were recruited. Whole body sagittal alignment including thoracic kyphosis (TK), lumbar lordosis (LL), pelvic tilt (PT), pelvic incidence (PI), sagittal vertical axis (SVA), T1-pelvic angle (TPA), knee-flex angle (KA) and ankle-flex angle (AA) were measured. …”
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    Global sagittal alignment of the spine, pelvis, lower limb after vertebral compression fracture and its effect on quality of life
  14. 135974
    “…METHODS: Consecutive patients with established CKD and estimated glomerular filtration rate (eGFR) < 59 ml/min/1.73 m(2) (n = 276) were compared to age/sex matched patients with eGFR ≥ 60 ml/min/1.73 m(2) (n = 242) and healthy controls (n = 38). …”
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    Cardiac biomarkers in chronic kidney disease are independently associated with myocardial edema and diffuse fibrosis by cardiovascular magnetic resonance
  15. 135975
    “…Data were summarised using descriptive statistics, and differences between TDF domain scores at the specific time points were analysed using Wilcoxon matched-pairs signed-rank tests. RESULTS: Sixty-four participants consented to complete surveys (97% women; 16% identified as Aboriginal), with 37 employed in clinical settings and 27 in non-clinical settings. …”
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    The impact of Healthy Conversation Skills training on health professionals’ barriers to having behaviour change conversations: a pre-post survey using the Theoretical Domains Framework
  16. 135976
    “…The findings of the current study indicated that the proposed model was a good match for the clinical eating disorder sample, but for the community sample only a revised model yielded acceptable statistical fit. …”
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    A new integrative model for the co-occurrence of non-suicidal self-injury behaviours and eating disorder symptoms
  17. 135977
    “…A target metastasis > 2 cm in each patient was imaged before and at 15 days after treatment on a 1.5T MR scanner using slice-matched IVIM-DWI and DCE-MRI protocols. MRI data were motion-corrected and tumour volumes of interest drawn on b=900 s/mm(2) diffusion-weighted images were transferred to DCE-MRI data for further analysis. …”
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    DCE-MRI is more sensitive than IVIM-DWI for assessing anti-angiogenic treatment-induced changes in colorectal liver metastases
  18. 135978
    “…METHODS: We included 118 participants (cognitively unimpaired [CU, n = 50], cognitively impaired [CI, n = 68]) from the ADNI study with a full plasma biomarker profile (Aβ42/40, GFAP, p-tau181, NfL) and matched amyloid imaging. Initially, we investigated how simulated CV variations impacted single-biomarker discriminative performance of amyloid status. …”
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    The accuracy and robustness of plasma biomarker models for amyloid PET positivity
  19. 135979
    “…CONCLUSIONS: TBS and uRDT had similar sensitivities, both were more sensitive than cRDT, and neither matched qPCR for detecting low density parasitaemia. uRDT could be considered an alternative to TBS in selected applications, such as CHMI or field diagnosis, where qualitative, dichotomous results for malaria infection might be sufficient. …”
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    Diagnostic performance and comparison of ultrasensitive and conventional rapid diagnostic test, thick blood smear and quantitative PCR for detection of low-density Plasmodium falciparum infections during a controlled human malaria infection study in Equatorial Guinea
  20. 135980
    “…Comparative data were taken from a cohort of patients without viral pneumonia admitted to ICU during the same period as the COVID-19 cohort (referred to as no viral pneumonia or ‘no viral’ group), and to a retrospective non-matched cohort of consecutive patients with Influenza A or B admitted to ICUs from 20 November 2017. …”
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    Comparative incidence of early and late bloodstream and respiratory tract co-infection in patients admitted to ICU with COVID-19 pneumonia versus Influenza A or B pneumonia versus no viral pneumonia: wales multicentre ICU cohort study
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