Orthogonal assays for the identification of inhibitors of the single-stranded nucleic acid binding protein YB-1

por Trevarton, AlexanderJ., Zhou, Yan, Yang, Dehua, Rewcastle, Gordon W., Flanagan, Jack U., Braithwaite, Antony, Shepherd, Peter R., Print, Cristin G., Wang, Ming-Wei, Lasham, Annette
Publicado 2019

Direct interaction of DNMT inhibitors to PrP(C) suppresses pathogenic process of prion

por Kim, Dae-Hwan, Ren, Chunyan, Ryou, Chongsuk, Li, Jiaojie
Publicado 2019

Cilastatin protects against imipenem-induced nephrotoxicity via inhibition of renal organic anion transporters (OATs)

por Huo, Xiaokui, Meng, Qiang, Wang, Changyuan, Zhu, Yanna, Liu, Zhihao, Ma, Xiaodong, Ma, Xiaochi, Peng, Jinyong, Sun, Huijun, Liu, Kexin
Publicado 2019

Discovery of WS-157 as a highly potent, selective and orally active EGFR inhibitor

por He, Pengxing, Niu, Shenghui, Wang, Shuai, Shi, Xiaojing, Feng, Siqi, Du, Linna, Zhang, Xuyang, Ma, Zhilu, Yu, Bin, Liu, Hongmin
Publicado 2019

Pulmonary immunization: deposition site is of minor relevance for influenza vaccination but deep lung deposition is crucial for hepatitis B vaccination

por Tomar, Jasmine, Tonnis, Wouter F., Patil, Harshad P., de boer, Anne H., Hagedoorn, Paul, Vanbever, Rita, Frijlink, Henderik W., Hinrichs, Wouter L.J.
Publicado 2019

Hepatic and intestinal biotransformation gene expression and drug disposition in a dextran sulfate sodium-induced colitis mouse model

por Fan, Xiaoyu, Ding, Xinxin, Zhang, Qing-Yu
Publicado 2020

Insulin-like growth factor 1 modulates the phosphorylation, expression, and activity of organic anion transporter 3 through protein kinase A signaling pathway

por Zhang, Jinghui, Yu, Zhou, You, Guofeng
Publicado 2020

Cdk5 knocking out mediated by CRISPR-Cas9 genome editing for PD-L1 attenuation and enhanced antitumor immunity

por Deng, Huan, Tan, Songwei, Gao, Xueqin, Zou, Chenming, Xu, Chenfeng, Tu, Kun, Song, Qingle, Fan, Fengjuan, Huang, Wei, Zhang, Zhiping
Publicado 2020

3-O-Acetyl-11-keto-β-boswellic acid ameliorated aberrant metabolic landscape and inhibited autophagy in glioblastoma

por Li, Wan, Ren, Liwen, Zheng, Xiangjin, Liu, Jinyi, Wang, Jinhua, Ji, Tengfei, Du, Guanhua
Publicado 2020

Targeting peptide-decorated biomimetic lipoproteins improve deep penetration and cancer cells accessibility in solid tumor

por Tan, Tao, Wang, Yuqi, Wang, Jing, Wang, Zhiwan, Wang, Hong, Cao, Haiqiang, Li, Jie, Li, Yaping, Zhang, Zhiwen, Wang, Siling
Publicado 2020

Therapeutic strategies for the costimulatory molecule OX40 in T-cell-mediated immunity

por Fu, Yu, Lin, Qing, Zhang, Zhirong, Zhang, Ling
Publicado 2020

A systematic strategy for screening therapeutic constituents of Schisandra chinensis (Turcz.) Baill infiltrated blood–brain barrier oriented in lesions using ethanol and water extr...

por Zhang, Yiwen, Lv, Xinyan, Qu, Jiameng, Zhang, Xin, Zhang, Mingyang, Gao, Hao, Zhang, Qian, Liu, Ran, Xu, Huarong, Li, Qing, Bi, Kaishun
Publicado 2020

Benzydamine inhibits osteoclast differentiation and bone resorption via down-regulation of interleukin-1β expression

por Son, Han Saem, Lee, Jiae, Lee, Hye In, Kim, Narae, Jo, You-Jin, Lee, Gong-Rak, Hong, Seong-Eun, Kwon, Minjeong, Kim, Nam Young, Kim, Hyun Jin, Park, Jin Ha, Lee, Soo Young, Jeong, Woojin
Publicado 2020

Protective role of berberine on ulcerative colitis through modulating enteric glial cells–intestinal epithelial cells–immune cells interactions

por Li, Heng, Fan, Chen, Lu, Huimin, Feng, Chunlan, He, Peilan, Yang, Xiaoqian, Xiang, Caigui, Zuo, Jianping, Tang, Wei
Publicado 2020

Selective phytochemicals targeting pancreatic stellate cells as new anti-fibrotic agents for chronic pancreatitis and pancreatic cancer

por Ramakrishnan, Puvanesswaray, Loh, Wei Mee, Gopinath, Subash C.B., Bonam, Srinivasa Reddy, Fareez, Ismail M., Mac Guad, Rhanye, Sim, Maw Shin, Wu, Yuan Seng
Publicado 2020

Traditional Chinese medicine for treatment of liver diseases: progress, challenges and opportunities

por Zhao, Chang-qing, Zhou, Yang, Ping, Jian, Xu, Lie-ming
Publicado 2014

Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells

por Zhang, Baoyuan, Lyu, Junfang, Yang, Eun Ju, Liu, Yifan, Wu, Changjie, Pardeshi, Lakhansing, Tan, Kaeling, Chen, Qiang, Xu, Xiaoling, Deng, Chu-Xia, Shim, Joong Sup
Publicado 2020

Synthesis, in vitro and in vivo biological evaluation of novel lappaconitine derivatives as potential anti-inflammatory agents

por Pang, Lei, Liu, Chun-Yan, Gong, Guo-Hua, Quan, Zhe-Shan
Publicado 2020

Potential therapeutic effects of dipyridamole in the severely ill patients with COVID-19

por Liu, Xiaoyan, Li, Zhe, Liu, Shuai, Sun, Jing, Chen, Zhanghua, Jiang, Min, Zhang, Qingling, Wei, Yinghua, Wang, Xin, Huang, Yi-You, Shi, Yinyi, Xu, Yanhui, Xian, Huifang, Bai, Fan, Ou, Changxing, Xiong, Bei, Lew, Andrew M., Cui, Jun, Fang, Rongli, Huang, Hui, Zhao, Jincun, Hong, Xuechuan, Zhang, Yuxia, Zhou, Fuling, Luo, Hai-Bin
Publicado 2020

Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites

por Kang, Sisi, Yang, Mei, Hong, Zhongsi, Zhang, Liping, Huang, Zhaoxia, Chen, Xiaoxue, He, Suhua, Zhou, Ziliang, Zhou, Zhechong, Chen, Qiuyue, Yan, Yan, Zhang, Changsheng, Shan, Hong, Chen, Shoudeng
Publicado 2020