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Modelos matemáticos
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541“…Mammalian inflammatory signaling, for which NF-κB is a principal transcription factor, is an exquisite example of how cellular signaling pathways can be regulated to produce different yet specific responses to different inflammatory insults. Mathematical models, tightly linked to experiment, have been instrumental in unraveling the forms of regulation in NF-κB signaling and their underlying molecular mechanisms. …”
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542“…These complex and unique features of the embryonic cardiomyocyte pacemaking and E–C coupling have never been assessed with mathematical modeling. Here, we suggest a novel mathematical model explaining how both of these mechanisms can coexist in the same embryonic cardiomyocytes. …”
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543por Tachikawa, Masashi“…In the present paper, we investigate the relation between the environmental fluctuation and the evolution of species diversity with a mathematical model of evolutionary ecology. In the model, individual organisms compete for a single restricted resource and the temporal fluctuation in the resource supply is introduced as the environmental fluctuation. …”
Publicado 2008
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544“…RESULTS: We have created deterministic mathematical models of the PKA module of the pathway, as well as the complete cAMP pathway. …”
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546por White, Lisa J, Maude, Richard J, Pongtavornpinyo, Wirichada, Saralamba, Sompob, Aguas, Ricardo, Van Effelterre, Thierry, Day, Nicholas PJ, White, Nicholas J“…Namely the spread of drug resistance, data scarcity and the adverse effects of failed elimination attempts. Mathematical models of various levels of complexity have been produced to consider the control and elimination of malaria infection. …”
Publicado 2009
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547“…METHODS: We construct a mathematical model of dopamine synthesis, release, and reuptake and use it to study homeostasis in single dopaminergic neuron terminals. …”
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548por Wattis, J. A. D., O’Malley, B., Blackburn, H., Pickersgill, L., Panovska, J., Byrne, H. M., Jackson, K. G.“…In this paper, we formulate a mathematical model of LDL endocytosis, consisting of a system of ordinary differential equations. …”
Publicado 2008
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549por Souza-e-Silva, Hallan, Savino, Wilson, Feijóo, Raúl A., Vasconcelos, Ana Tereza Ribeiro“…Herein we built a cellular automata-based mathematical model for thymocyte migration and development. …”
Publicado 2009
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550por Pearson, T., Wattis, J. A. D., O’Malley, B., Pickersgill, L., Blackburn, H., Jackson, K. G., Byrne, H. M.“…We formulate a mathematical model to study the binding and internalization (endocytosis) of LDL and VLDL particles by hepatocytes in culture. …”
Publicado 2008
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553“…BACKGROUND: It has not been assessed before whether mathematical models described in the literature for prescriptions of exercise can be used for fibromyalgia syndrome patients. …”
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554“…METHODS: We construct a mathematical model of serotonin synthesis, release, and reuptake in a single serotonergic neuron terminal. …”
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555por Kronik, Natalie, Kogan, Yuri, Elishmereni, Moran, Halevi-Tobias, Karin, Vuk-Pavlović, Stanimir, Agur, Zvia“…We hypothesized that the efficacy of treatment will be enhanced by individualized vaccination regimens tailored by simple mathematical models. METHODOLOGY/PRINCIPAL FINDINGS: We developed a general mathematical model encompassing the basic interactions of a vaccine, immune system and PCa cells, and validated it by the results of a clinical trial testing an allogeneic PCa whole-cell vaccine. …”
Publicado 2010
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556por Maude, Richard J., Lubell, Yoel, Socheat, Duong, Yeung, Shunmay, Saralamba, Sompob, Pongtavornpinyo, Wirichada, Cooper, Ben S., Dondorp, Arjen M., White, Nicholas J., White, Lisa J.“…Different strategies can be evaluated much more rapidly than is possible through trial and error in the field. Mathematical modelling has great potential as a tool to guide and inform current elimination efforts. …”
Publicado 2010
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557“…The mathematical model of the integrated process of mercury contaminated wastewater bioremediation in a fixed-bed industrial bioreactor is presented. …”
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558por Perry, J. N., Devos, Y., Arpaia, S., Bartsch, D., Gathmann, A., Hails, R. S., Kiss, J., Lheureux, K., Manachini, B., Mestdagh, S., Neemann, G., Ortego, F., Schiemann, J., Sweet, J. B.Enlace del recurso
Publicado 2011
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