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73161por Dugger, Brittany N., Davis, Kathryn, Malek-Ahmadi, Michael, Hentz, Joseph G., Sandhu, Shawn, Beach, Thomas G., Adler, Charles H., Caselli, Richard J., Johnson, Travis A., Serrano, Geidy E., Shill, Holly A., Belden, Christine, Driver-Dunckley, Erika, Caviness, John N., Sue, Lucia I., Jacobson, Sandra, Powell, Jessica, Sabbagh, Marwan N.“…Neuropathological lesions, including neuritic plaques, neurofibrillary tangles (NFTs), Lewy bodies (LBs), infarcts, cerebral white matter rarefaction (CWMR), cerebral amyloid angiopathy (CAA), and concurrent major clinicopathological diagnoses, including Parkinson’s disease (PD) were analyzed. …”
Publicado 2015
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73162“…High bed occupancy rate (BOR) has been considered as a matter of reduced patient comfort and privacy. Most hospitals in Singapore operate under BORs above 85 %. …”
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73163por Muala, Ala, Rankin, Gregory, Sehlstedt, Maria, Unosson, Jon, Bosson, Jenny A., Behndig, Annelie, Pourazar, Jamshid, Nyström, Robin, Pettersson, Esbjörn, Bergvall, Christoffer, Westerholm, Roger, Jalava, Pasi I., Happo, Mikko S., Uski, Oskari, Hirvonen, Maija-Riitta, Kelly, Frank J., Mudway, Ian S., Blomberg, Anders, Boman, Christoffer, Sandström, Thomas“…In parallel experiments, the toxicity of the particulate matter (PM) generated during the chamber exposures was investigated in vitro using the RAW264.7 macrophage cell line. …”
Publicado 2015
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73164por Wong, Chit Ming, Lai, Hak Kan, Tsang, Hilda, Thach, Thuan Quoc, Thomas, G. Neil, Lam, Kin Bong Hubert, Chan, King Pan, Yang, Lin, Lau, Alexis K.H., Ayres, Jon G., Lee, Siu Yin, Man Chan, Wai, Hedley, Anthony J., Lam, Tai Hing“…BACKGROUND: A limited number of studies on long-term effects of particulate matter with aerodynamic diameter < 2.5 μm (PM(2.5)) on health suggest it can be an important cause of morbidity and mortality. …”
Publicado 2015
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73165por Schembari, Anna, de Hoogh, Kees, Pedersen, Marie, Dadvand, Payam, Martinez, David, Hoek, Gerard, Petherick, Emily S., Wright, John, Nieuwenhuijsen, Mark J.“…Exposures to particulate matter (≤ 10 μm, PM(10); ≤ 2.5 μm, PM(2.5)), PM(2.5) absorbance, and nitrogen oxides (NO(x), NO(2)) were estimated using land-use regressions models. …”
Publicado 2015
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73166“…Aqueous extract of S. crispus leaves collected from Kelantan exhibited the highest values: TPC [12.62 mg gallic acid equivalents (GAE)/g dry matter (DM)], TFC (7.44 mg quercetin equivalents (QE)/g DM), TSC (44.7 mg diosgenin equivalents (DE)/g DM), DPPH (73.8 %), and FRAP (267.5 μM of Fe (II)/g) activity with a half-maximal inhibitory concentration (IC(50)) of 44.1 μg/mL compared to the extracts of leaves collected from the other two locations. …”
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73167por Annicchiarico, Paolo, Nazzicari, Nelson, Li, Xuehui, Wei, Yanling, Pecetti, Luciano, Brummer, E. Charles“…RESULTS: Landrace and variety material from two genetically-contrasting reference populations, i.e., 124 elite genotypes adapted to the Po Valley (sub-continental climate; PV population) and 154 genotypes adapted to Mediterranean-climate environments (Me population), were genotyped by GBS and phenotyped in separate environments for dry matter yield of their dense-planted half-sib progenies. …”
Publicado 2015
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73168por Retico, Alessandra, Giuliano, Alessia, Tancredi, Raffaella, Cosenza, Angela, Apicella, Fabio, Narzisi, Antonio, Biagi, Laura, Tosetti, Michela, Muratori, Filippo, Calderoni, Sara“…Specifically, 76 young children with ASD (38 males and 38 females; 2–7 years of age; mean = 53 months, standard deviation = 17 months) were evaluated employing a support vector machine (SVM)-based analysis of the grey matter (GM). Group comparisons consisted of 76 age-, gender- and non-verbal-intelligence quotient-matched children with typical development or idiopathic developmental delay without autism. …”
Publicado 2016
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73169Mitochondrial oxidative DNA damage and exposure to particulate air pollution in mother-newborn pairspor Grevendonk, Lotte, Janssen, Bram G., Vanpoucke, Charlotte, Lefebvre, Wouter, Hoxha, Mirjam, Bollati, Valentina, Nawrot, Tim S.“…BACKGROUND: Studies emphasize the importance of particulate matter (PM) in the formation of reactive oxygen species and inflammation. …”
Publicado 2016
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73170por Ma, Zongwei, Hu, Xuefei, Sayer, Andrew M., Levy, Robert, Zhang, Qiang, Xue, Yingang, Tong, Shilu, Bi, Jun, Huang, Lei, Liu, Yang“…BACKGROUND: Three decades of rapid economic development is causing severe and widespread PM(2.5) (particulate matter ≤ 2.5 μm) pollution in China. However, research on the health impacts of PM(2.5) exposure has been hindered by limited historical PM(2.5) concentration data. …”
Publicado 2015
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73171por Heffernan, Kayla Joanne, Chang, Shanton, Maclean, Skye Tamara, Callegari, Emma Teresa, Garland, Suzanne Marie, Reavley, Nicola Jane, Varigos, George Andrew, Wark, John Dennis“…The app was developed through participatory action research involving medical and human computer interaction researchers, subject matter expert clinicians, external developers, and target users. …”
Publicado 2016
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73172por Janelidze, Shorena, Zetterberg, Henrik, Mattsson, Niklas, Palmqvist, Sebastian, Vanderstichele, Hugo, Lindberg, Olof, van Westen, Danielle, Stomrud, Erik, Minthon, Lennart, Blennow, Kaj, Hansson, Oskar“…However, lower Aβ38, Aβ40, and Aβ42, but not the ratios, correlated with non‐AD‐specific subcortical changes, that is, larger lateral ventricles and white matter lesions. Further, the Aβ42/Aβ40 and Aβ42/Aβ38 ratios showed increased accuracy compared to Aβ42 when distinguishing AD from dementia with Lewy bodies or Parkinson's disease dementia and subcortical vascular dementia, where all Aβs (including Aβ42) were decreased. …”
Publicado 2016
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73173por Hou, Lifang, Barupal, Jitendra, Zhang, Wei, Zheng, Yinan, Liu, Lei, Zhang, Xiao, Dou, Chang, McCracken, John P., Díaz, Anaité, Motta, Valeria, Sanchez-Guerra, Marco, Wolf, Katherine Rose, Bertazzi, Pier Alberto, Schwartz, Joel D., Wang, Sheng, Baccarelli, Andrea A.“…We investigated associations of short-term air pollution exposure, using measures of personal PM(2.5) (particulate matter ≤ 2.5 μm) and elemental carbon (EC), and ambient PM(10) (≤ 10 μm), with blood NanoString nCounter miRNA profiles at two exams separated by 1–2 weeks. …”
Publicado 2015
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73174“…Furthermore, SOC (75.15 %) was the major constituent to the soil organic matter (SOM) as compared to the STN (5.85 %). The vegetation type and litter both showed high impact on STN and STC, while altitude and HB showed very little or no impact on carbon and nitrogen concentrations. …”
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73175por Kulkarni, Hemant, Mamtani, Manju, Peralta, Juan, Almeida, Marcio, Dyer, Thomas D., Goring, Harald H., Johnson, Matthew P., Duggirala, Ravindranath, Mahaney, Michael C., Olvera, Rene L., Almasy, Laura, Glahn, David C., Williams-Blangero, Sarah, Curran, Joanne E., Blangero, John“…OBJECTIVE: While the role of type 2 diabetes (T2D) in inducing endothelial dysfunction is fairly well-established the etiological role of endothelial dysfunction in the onset of T2D is still a matter of debate. In the light of conflicting evidence in this regard, we conducted a prospective study to determine the association of circulating levels of soluble intercellular adhesion molecule 1 (sICAM-1) and soluble vessel cell adhesion molecule 1 (sVCAM-1) with incident T2D. …”
Publicado 2016
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73176“…Phagocytosis is crucial for normal CNS development and maintenance, but it can be either beneficial or detrimental after injury or disease. For instance, white matter damage releases myelin debris that must be cleared by microglia in order for re-myelination to occur. …”
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73177por Marignier, R., Ruiz, A., Cavagna, S., Nicole, A., Watrin, C., Touret, M., Parrot, S., Malleret, G., Peyron, C., Benetollo, C., Auvergnon, N., Vukusic, S., Giraudon, P.“…In parallel, myelin was altered, as shown by the decrease of myelin basic protein staining by up to 46 and 22 % in the gray and white matter of the NMO-rats spinal cord, respectively (p = 0.03). …”
Publicado 2016
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73178por Llonch, Pol, Somarriba, Miguel, Duthie, Carol-Anne, Haskell, Marie J., Rooke, John A., Troy, Shane, Roehe, Rainer, Turner, Simon P.“…Over a 56-day period individual animal dry matter intake (DMI) and weekly body weight was measured. …”
Publicado 2016
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73179por Pieters, Nicky, Janssen, Bram G., Dewitte, Harrie, Cox, Bianca, Cuypers, Ann, Lefebvre, Wouter, Smeets, Karen, Vanpoucke, Charlotte, Plusquin, Michelle, Nawrot, Tim S.“…There is inconclusive evidence concerning the mechanistic effects of airborne particulate matter (PM) exposure on biomolecular markers of aging. …”
Publicado 2015
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73180por Peterson, Kim, Floyd, Nicole, Ferguson, Lauren, Christensen, Vivian, Helfand, Mark“…Operational partners were primarily non-academic subject matter experts with VA operations’ decision-making authority. …”
Publicado 2016
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