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73961por Yamada, Hirotsugu, Tanaka, Atsushi, Kusunose, Kenya, Amano, Rie, Matsuhisa, Munehide, Daida, Hiroyuki, Ito, Masaaki, Tsutsui, Hiroyuki, Nanasato, Mamoru, Kamiya, Haruo, Bando, Yasuko K., Odawara, Masato, Yoshida, Hisako, Murohara, Toyoaki, Sata, Masataka, Node, Koichi“…However, the influence of dipeptidyl peptidase 4 inhibitors on cardiac function is controversial and a major matter of clinical concern. We therefore evaluated the effect of sitagliptin on echocardiographic parameters of diastolic function in patients with type 2 diabetes as a sub-analysis of the PROLOGUE study. …”
Publicado 2017
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73962por Seabury, Christopher M., Oldeschulte, David L., Saatchi, Mahdi, Beever, Jonathan E., Decker, Jared E., Halley, Yvette A., Bhattarai, Eric K., Molaei, Maral, Freetly, Harvey C., Hansen, Stephanie L., Yampara-Iquise, Helen, Johnson, Kristen A., Kerley, Monty S., Kim, JaeWoo, Loy, Daniel D., Marques, Elisa, Neibergs, Holly L., Schnabel, Robert D., Shike, Daniel W., Spangler, Matthew L., Weaber, Robert L., Garrick, Dorian J., Taylor, Jeremy F.“…Using actual and imputed Illumina 778K genotypes for 3887 U.S. beef cattle from 3 populations (Angus, Hereford, SimAngus), we performed genome-wide association analyses for feed efficiency and growth traits including average daily gain (ADG), dry matter intake (DMI), mid-test metabolic weight (MMWT), and residual feed intake (RFI), with marker-based heritability estimates produced for all traits and populations. …”
Publicado 2017
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73963por Kim, H. J., Nam, S. O., Jeong, J. H., Fang, L. H., Yoo, H. B., Yoo, S. H., Hong, J. S., Son, S. W., Ha, S. H., Kim, Y. Y.“…In digestibility trial, there was no significant difference in dry matter, crude fat, crude ash and nitrogen digestibility. …”
Publicado 2017
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73964por Chen, Chiu-Ying, Hung, Hui-Jung, Chang, Kuang-Hsi, Hsu, Chung Y., Muo, Chih-Hsin, Tsai, Chon-Haw, Wu, Trong-Neng“…None of the chemical compounds (SO(2), O(3), CO, NO(x), NO, NO(2), THC, CH(4), or NMHC) significantly affected the incidence of PD except for particulate matter. PM(10) exposure showed significant effects on the likelihood of PD development (T3 level: > 65μg/m(3) versus T1 level: ≤ 54μg/m(3); OR = 1.35, 95% CI = 1.12–1.62, 0.001 ≤ P < 0.01). …”
Publicado 2017
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73965por Ku, Tingting, Li, Ben, Gao, Rui, Zhang, Yingying, Yan, Wei, Ji, Xiaotong, Li, Guangke, Sang, Nan“…BACKGROUND: PM(2.5) (particulate matter ≤ 2.5 μm) is one of the leading environmental risk factors for the global burden of disease. …”
Publicado 2017
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73966por Naccache, Samia, Bender, Jeffery, Desai, Jay, Van, Tam, Meyers, Lindsay, Jones, Jay, Mongkolrattanothai, Kanokporn, Bard, Jennifer Dien“…All had acute onset patchy weakness involving mostly the upper limbs and grey matter involvement on MRI. 6/7 reported fever/upper respiratory infection prior to AFM onset. …”
Publicado 2017
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73967por Howell, Jennifer C., Watts, Kelly D., Parker, Monica W., Wu, Junjie, Kollhoff, Alexander, Wingo, Thomas S., Dorbin, Cornelya D., Qiu, Deqiang, Hu, William T.“…We compared levels of CSF markers for β-amyloid (Aβ42, Aβ40), total and phosphorylated tau (t-tau and p-tau(181), respectively), endothelial dysfunction (soluble vascular cell adhesion molecule 1, soluble intercellular adhesion molecule 1), α-synuclein, and neurodegeneration (neurofilament light chain [NfL]), as well as MRI markers, for hippocampal atrophy and cerebrovascular disease (white matter hyperintensity [WMH] volume). RESULTS: Sixty-five older African Americans (average age, 69.1 years) and 70 older Caucasians (average age, 70.8 years) were included. …”
Publicado 2017
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73968“…Fractal analysis, performed on a grey matter mask, was done by estimating the Hurst exponent in the frequency domain using a power spectral density approach and refining the estimation in the time domain with de-trended fluctuation analysis and signal summation conversion methods. …”
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73969“…This review examines the current literature on the effects of future emissions and climate change on particulate matter (PM) and O(3) air quality and on the consequent health impacts, with a focus on Europe. …”
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73970por Powell-Jackson, Timothy, Fabbri, Camilla, Dutt, Varun, Tougher, Sarah, Singh, Kultar“…The framing of the health information message did not appear to matter. TRIAL REGISTRATION: The trial is registered with ISRCTN, number ISRCTN84560580.…”
Publicado 2018
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73971por Mei, Mei, Song, Haojun, Chen, Lina, Hu, Bin, Bai, Ru, Xu, Diandou, Liu, Ying, Zhao, Yuliang, Chen, Chunying“…Although late-onset adult asthma seems to be more attributable to environmental risk factors, limited data is available on the impact of early-life exposure to size-fractionated ambient particulate matter (PM) on asthma in adults. We aimed to determine the effect on the development and exacerbation of asthma in the adult after the mice were exposed as juveniles to three size-fractionated ambient particulates collected from Beijing. …”
Publicado 2018
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73972por Calvo, Ana, O’Hanlon, Erik, Coughlan, Helen, Kelleher, Ian, Clarke, Mary, Cannon, Mary“…The ENIGMA consortium identified that patients with schizophrenia had smaller hippocampus, amygdala, thalamus, accumbens and intracranial volumes.1 Reduced hippocampal volume is one of the most consistent findings in schizophrenia research.2–4 Also, Previous research has reported differences in hippocampal volume and white matter integrity in young adolescents who report psychotic experiences.5,6 However there has been little longitudinal research to investigate the developmental trajectory of these regions in adolescence with an increased susceptibility to psychotic disorders. …”
Publicado 2018
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73973por González-Rodríguez, Alexandre, Estrada, Francesc, Montalvo, Itziar, Monreal, José Antonio, Palao, Diego, Labad, Javier“…Brain dysfunction (n=7): hypoperfusion in cerebral blood flow in temporal and parietal lobes, left side (n=5), right side (n=1) and lack of basal ganglia and subcortical gray matter lesions (n=1). Genetic evidence (n=1): implications of DRD2 Ser311Cys, DRD3 Ser9Gly and TH VNTR polymorphisms. …”
Publicado 2018
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73974por Ruth, Zhou De-Hui, Marcus, Chiu Yu-Lung, William, Lo Tak-Lam, Alison, Lo Wai Fan, Sing, Wong Siu“…These metaphors vividly describe the unexpectedness of episodes that schizophrenia outpatients experienced as well as the explosive damages that schizophrenia caused their families. 73.2% participants used “climbing up the mountain” to describe their caregiver experiences and emphasize on the necessity of overcoming difficulties during the caregiving process. 67.5% caregivers preferred to use the “rescue work of firefighters” to describe the nature of their caregiving. 50% participants indicated the caregiving work as a burden that they chose not to lay down no matter how heavy it is, whereas 17.5% caregivers regarded it as a burden that they cannot shake off and always restricts their freedom. …”
Publicado 2018
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73975por Cropley, Vanessa, Ganella, Eleni, Wannan, Cassandra, Zalesky, Andrew, Van Rheenen, Tamsyn, Bousman, Chad, Everall, Ian, Fornito, Alexander, Pantelis, Christos“…The whole striatum (caudate, putamen and nucleus accumbens) and the left and right dorsal striatum were separately seeded as regions of interest, and Pearson’s correlations between the seeds and all other voxels comprising cortical and subcortical gray matter were investigated. For brain regions that showed significant group differences in FC with the striatal seeds, Pearson’s correlations explored the relationship between the strength of connectivity with positive symptoms and attentional set-shifting (extradimensional shift errors) as measured with the CANTAB intra-/extradimensional set shift task. …”
Publicado 2018
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73976por Dancy-Scott, Nicole, Dutcher, Gale A, Keselman, Alla, Hochstein, Colette, Copty, Christina, Ben-Senia, Diane, Rajan, Sampada, Asencio, Maria Guadalupe, Choi, Jason Jongwon“…A text mining module within the KNIME Analytics Platform, an open source software, was then used to mine the partially processed data to create a terminology corpus of key HIV terms. Subject matter experts grouped the terms into categories. …”
Publicado 2018
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73977“…BACKGROUND: The anticoagulation of atrial fibrillation catheter ablation during the perioperative stage does matter and should be treated with discretion. We aimed to assess impact of three important genes participating in vitamin K cycle (i.e. …”
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73978por Datzmann, Thomas, Markevych, Iana, Trautmann, Freya, Heinrich, Joachim, Schmitt, Jochen, Tesch, Falko“…Exposures, derived from freely available 3rd party data, included particulate matter with aerodynamic diameter of less than 10 μm (PM(10)) and nitrogen dioxide (N0(2)) as well as green space (Normalized Difference Vegetation Index - NDVI). …”
Publicado 2018
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73979“…Despite these differences, the average standing stock of organic matter was higher in the eucalypt than in the deciduous forest. …”
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73980por Marioni, Riccardo E., McRae, Allan F., Bressler, Jan, Colicino, Elena, Hannon, Eilis, Li, Shuo, Prada, Diddier, Smith, Jennifer A, Trevisi, Letizia, Tsai, Pei-Chien, Vojinovic, Dina, Simino, Jeannette, Levy, Daniel, Liu, Chunyu, Mendelson, Michael, Satizabal, Claudia L., Yang, Qiong, Jhun, Min A., Kardia, Sharon L. R., Zhao, Wei, Bandinelli, Stefania, Ferrucci, Luigi, Hernandez, Dena G., Singleton, Andrew B., Harris, Sarah E., Starr, John M., Kiel, Douglas P., McLean, Robert R., Just, Allan C., Schwartz, Joel, Spiro, Avron, Vokonas, Pantel, Amin, Najaf, Ikram, M. Arfan, Uitterlinden, Andre G., van Meurs, Joyce B. J., Spector, Tim D., Steves, Claire, Baccarelli, Andrea A., Bell, Jordana T., van Duijn, Cornelia M., Fornage, Myriam, Hsu, Yi-Hsiang, Mill, Jonathan, Mosley, Thomas H., Seshadri, Sudha, Deary, Ian J.“…Neither probe showed evidence of longitudinal change in late-life or associations with white matter brain MRI measures in one cohort with these data. …”
Publicado 2018
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