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  1. 74381
    “…BACKGROUND: The prognostic role of tumor-related parameters in diffuse large B cell lymphoma (DLBCL) is a matter of controversy. METHODS: We investigated the prognostic value of phenotypic and genotypic profiles in DLBCL in clinical trial (NCT00544219) patients homogenously treated with six cycles of rituximab, cyclophosphamide, hydroxydaunorubicin, vincristine, prednisone (R-CHOP), followed by two cycles of R (R-CHOP-14). …”
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    Multiparameter analysis of homogeneously R-CHOP-treated diffuse large B cell lymphomas identifies CD5 and FOXP1 as relevant prognostic biomarkers: report of the prospective SAKK 38/07 study
  2. 74382
    “…BACKGROUND: In dairy mixed production systems, maximizing pasture intake and total mixed ration (TMR) supplementation are management tools used to increase dry matter and energy intake in early lactation. The objective was to evaluate metabolic and endocrine profiles and hepatic gene expression of Holstein cows fed either TMR ad libitum (without grazing) or diets combining TMR (50 % ad libitum DM intake) and pasture with different grazing strategies (6 h in one grazing session or 9 h in two grazing sessions) in early lactation. …”
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    Metabolic and endocrine profiles and hepatic gene expression of Holstein cows fed total mixed ration or pasture with different grazing strategies during early lactation
  3. 74383
    “…Nitrogen oxides (NO(2), NO(x)) and particulate matter (PM) with diameters of ≤ 2.5 μm (PM(2.5)), ≤ 10 μm (PM(10)), and between 2.5 and 10 μm (PM(coarse)), and PM(2.5) absorbance were estimated for birth addresses by land-use regression models based on monitoring campaigns performed between 2008 and 2011. …”
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    Air Pollution Exposure during Pregnancy and Childhood Autistic Traits in Four European Population-Based Cohort Studies: The ESCAPE Project
  4. 74384
    “…Sporadic mild cognitive impairment patients were further divided into (11) C-Pittsburgh compound B-positive ( n = 13; 62.0 ± 6.4; seven male) and (11) C-Pittsburgh compound B-negative ( n = 4; 61.8 ± 7.5 years old; two male) groups using a neocortical standardized uptake value ratio cut-off value of 1.41, which was calculated with respect to the cerebellar grey matter. All baseline participants underwent multitracer positron emission tomography scans, cerebrospinal fluid biomarker analysis and neuropsychological assessment. …”
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    Diverging longitudinal changes in astrocytosis and amyloid PET in autosomal dominant Alzheimer’s disease
  5. 74385
    “…SUMMARY: Seeds of Wrightia antidysenterica (WA) Linn. free from any foreign matter were selected for the study. Loss on drying revealed 6.535% moisture content; total ash indicating of total inorganic content was found to be 5.12%; acid insoluble ash is the acid insoluble part of total ash, mainly silica, WA showed 0.393% acid insoluble ash; ethanol and water soluble extractive is indicative of percentage active constituents were found to be 25.66 and 20.854%, respectively. …”
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    A Clinico-analytical Study on Seed of Wrightia antidysenterica Linn. as a Therapeutic Emetic Agent (Vamaka Yoga) in the Management of Psoriasis
  6. 74386
    “…The results showed that gene silencing significantly affected tdNFC (42.3 (NT) vs. 38.7 (HB12) vs. 37.4% Dry Matter (TT8); p = 0.016) and tdCP (20.8 (NT) vs. 19.4 (HB12) vs. 22.3% DM (TT8); p = 0.009). …”
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    Gene-Silencing-Induced Changes in Carbohydrate Conformation in Relation to Bioenergy Value and Carbohydrate Subfractions in Modeled Plant (Medicago sativa) with Down-Regulation of HB12 and TT8 Transcription Factors
  7. 74387
    “…Ambient PM2.5 (particulate matter with aerodynamic diameter ≤ 2.5 μm) is an emerging determinant of glucose dysregulation. …”
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    Particulate Air Pollution and Fasting Blood Glucose in Nondiabetic Individuals: Associations and Epigenetic Mediation in the Normative Aging Study, 2000–2011
  8. 74388
    “…RESULTS: Postpartal dry matter intake, milk yield, and energy-corrected milk were higher in CON and OVE + SM compared with OVE. …”
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    Supplemental Smartamine M in higher-energy diets during the prepartal period improves hepatic biomarkers of health and oxidative status in Holstein cows
  9. 74389
    por Traylor, Matthew, Malik, Rainer, Nalls, Mike A., Cotlarciuc, Ioana, Radmanesh, Farid, Thorleifsson, Gudmar, Hanscombe, Ken B., Langefeld, Carl, Saleheen, Danish, Rost, Natalia S., Yet, Idil, Spector, Tim D., Bell, Jordana T., Hannon, Eilis, Mill, Jonathan, Chauhan, Ganesh, Debette, Stephanie, Bis, Joshua C., Longstreth, W.T., Ikram, M. Arfan, Launer, Lenore J., Seshadri, Sudha, Hamilton‐Bruce, Monica Anne, Jimenez‐Conde, Jordi, Cole, John W., Schmidt, Reinhold, Słowik, Agnieszka, Lemmens, Robin, Lindgren, Arne, Melander, Olle, Grewal, Raji P., Sacco, Ralph L., Rundek, Tatjana, Rexrode, Kathryn, Arnett, Donna K., Johnson, Julie A., Benavente, Oscar R., Wasssertheil‐Smoller, Sylvia, Lee, Jin‐Moo, Pulit, Sara L., Wong, Quenna, Rich, Stephen S., de Bakker, Paul I.W., McArdle, Patrick F., Woo, Daniel, Anderson, Christopher D., Xu, Huichun, Heitsch, Laura, Fornage, Myriam, Jern, Christina, Stefansson, Kari, Thorsteinsdottir, Unnur, Gretarsdottir, Solveig, Lewis, Cathryn M., Sharma, Pankaj, Sudlow, Cathie L.M., Rothwell, Peter M., Boncoraglio, Giorgio B., Thijs, Vincent, Levi, Chris, Meschia, James F., Rosand, Jonathan, Kittner, Steven J., Mitchell, Braxton D., Dichgans, Martin, Worrall, Bradford B., Markus, Hugh S.
    Publicado 2017
    “…The lead single‐nucleotide polymorphism (rs12445022) was also associated with cerebral white matter hyperintensities (OR [95% CI] = 1.10 [1.05–1.16]; p = 5.3 × 10(−5); N = 3,670), but not intracerebral hemorrhage (OR [95% CI] = 0.97 [0.84–1.12]; p = 0.71; 1,545 cases, 1,481 controls). rs12445022 is associated with mRNA expression of ZCCHC14 in arterial tissues (p = 9.4 × 10(−7)) and DNA methylation at probe cg16596957 in whole blood (p = 5.3 × 10(−6)). …”
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    Genetic variation at 16q24.2 is associated with small vessel stroke
  10. 74390
    por Schmaal, L, Hibar, D P, Sämann, P G, Hall, G B, Baune, B T, Jahanshad, N, Cheung, J W, van Erp, T G M, Bos, D, Ikram, M A, Vernooij, M W, Niessen, W J, Tiemeier, H, Hofman, A, Wittfeld, K, Grabe, H J, Janowitz, D, Bülow, R, Selonke, M, Völzke, H, Grotegerd, D, Dannlowski, U, Arolt, V, Opel, N, Heindel, W, Kugel, H, Hoehn, D, Czisch, M, Couvy-Duchesne, B, Rentería, M E, Strike, L T, Wright, M J, Mills, N T, de Zubicaray, G I, McMahon, K L, Medland, S E, Martin, N G, Gillespie, N A, Goya-Maldonado, R, Gruber, O, Krämer, B, Hatton, S N, Lagopoulos, J, Hickie, I B, Frodl, T, Carballedo, A, Frey, E M, van Velzen, L S, Penninx, B W J H, van Tol, M-J, van der Wee, N J, Davey, C G, Harrison, B J, Mwangi, B, Cao, B, Soares, J C, Veer, I M, Walter, H, Schoepf, D, Zurowski, B, Konrad, C, Schramm, E, Normann, C, Schnell, K, Sacchet, M D, Gotlib, I H, MacQueen, G M, Godlewska, B R, Nickson, T, McIntosh, A M, Papmeyer, M, Whalley, H C, Hall, J, Sussmann, J E, Li, M, Walter, M, Aftanas, L, Brack, I, Bokhan, N A, Thompson, P M, Veltman, D J
    Publicado 2017
    “…Adults with MDD had thinner cortical gray matter than controls in the orbitofrontal cortex (OFC), anterior and posterior cingulate, insula and temporal lobes (Cohen's d effect sizes: −0.10 to −0.14). …”
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    Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group
  11. 74391
    “…Among 69% (34/49) of the patients with neuroimaging abnormalities, ventriculomegaly (37%, 18/49) and periventricular white matter injury (18%, 9/49) were most common. Twenty-one patients (43%) received ganciclovir or valganciclovir treatment (median 41 days; range, 2–188 days). …”
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    The Incidence of Symptomatic Congenital Cytomegalovirus (CMV) Infection in Korea; A 15-year Multi-center Study
  12. 74392
    “…BACKGROUND: The resurgence of vaccine preventable diseases in young infants is a matter of concern worldwide. The aim of our study was to determine the seroprevalance of protective antibodies against diphtheria, pertussis, measles, mumps and rubella antigens in cord blood among term Indian newborns, at birth. …”
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    Cord Blood Antibody Seroprevalance Against Diphtheria, Pertussis, Measles, Mumps and Rubella among Term Healthy Indian Newborns
  13. 74393
    “…By setting the priorities with patients, carers, the public and health care professionals, research can look at the issues that really matter to people who are receiving or delivering care in hospital wards. …”
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    Determining priorities for research to improve fundamental care on hospital wards
  14. 74394
    “…The values of [Formula: see text] and [Formula: see text] were well estimated (r(2) = 0.81 and r(2) = 0.88 respectively) while the dry matter content, [Formula: see text] , was poorly estimated (r(2) = 0.00). …”
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    Estimation of leaf traits from reflectance measurements: comparison between methods based on vegetation indices and several versions of the PROSPECT model
  15. 74395
    “…We spend the majority of our lives indoors and can be exposed to a number of pollutants smaller than 2.5 microns (particulate matter, PM(2.5)) resulting in detrimental health effects. …”
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    Effect of Using an Indoor Air Quality Sensor on Perceptions of and Behaviors Toward Air Pollution (Pittsburgh Empowerment Library Study): Online Survey and Interviews
  16. 74396
    “…These findings are of relevance in schizophrenia patients as fewer and delayed relapses over the course of a lifetime of schizophrenia may provide higher protection against grey matter damage and help preserve functioning.…”
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    T45. A COMPARISON OF SCHIZOPHRENIA RELAPSE RATES OF 3 PALIPERIDONE FORMULATIONS, ONCE-DAILY, ONCE-MONTHLY AND ONCE EVERY-3-MONTH: POST-HOC ANALYSIS FROM 3 RANDOMIZED CONTROLLED TRIALS
  17. 74397
    por Franzmeier, Nicolai, Düzel, Emrah, Jessen, Frank, Buerger, Katharina, Levin, Johannes, Duering, Marco, Dichgans, Martin, Haass, Christian, Suárez-Calvet, Marc, Fagan, Anne M, Paumier, Katrina, Benzinger, Tammie, Masters, Colin L, Morris, John C, Perneczky, Robert, Janowitz, Daniel, Catak, Cihan, Wolfsgruber, Steffen, Wagner, Michael, Teipel, Stefan, Kilimann, Ingo, Ramirez, Alfredo, Rossor, Martin, Jucker, Mathias, Chhatwal, Jasmeer, Spottke, Annika, Boecker, Henning, Brosseron, Frederic, Falkai, Peter, Fliessbach, Klaus, Heneka, Michael T, Laske, Christoph, Nestor, Peter, Peters, Oliver, Fuentes, Manuel, Menne, Felix, Priller, Josef, Spruth, Eike J, Franke, Christiana, Schneider, Anja, Kofler, Barbara, Westerteicher, Christine, Speck, Oliver, Wiltfang, Jens, Bartels, Claudia, Araque Caballero, Miguel Ángel, Metzger, Coraline, Bittner, Daniel, Weiner, Michael, Lee, Jae-Hong, Salloway, Stephen, Danek, Adrian, Goate, Alison, Schofield, Peter R, Bateman, Randall J, Ewers, Michael
    Publicado 2018
    “…For each participant, global left frontal cortex connectivity was computed as the average resting state functional connectivity between the left frontal cortex (seed) and each voxel in the grey matter. As a marker of disease stage, we applied estimated years from symptom onset in autosomal dominantly inherited Alzheimer’s disease and cerebrospinal fluid tau levels in sporadic Alzheimer’s disease cases. …”
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    Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer’s disease
  18. 74398
    por Olalde, Iñigo, Brace, Selina, Allentoft, Morten E., Armit, Ian, Kristiansen, Kristian, Booth, Thomas, Rohland, Nadin, Mallick, Swapan, Szécsényi-Nagy, Anna, Mittnik, Alissa, Altena, Eveline, Lipson, Mark, Lazaridis, Iosif, Harper, Thomas K., Patterson, Nick, Broomandkhoshbacht, Nasreen, Diekmann, Yoan, Faltyskova, Zuzana, Fernandes, Daniel, Ferry, Matthew, Harney, Eadaoin, de Knijff, Peter, Michel, Megan, Oppenheimer, Jonas, Stewardson, Kristin, Barclay, Alistair, Alt, Kurt Werner, Liesau, Corina, Ríos, Patricia, Blasco, Concepción, Miguel, Jorge Vega, García, Roberto Menduiña, Fernández, Azucena Avilés, Bánffy, Eszter, Bernabò-Brea, Maria, Billoin, David, Bonsall, Clive, Bonsall, Laura, Allen, Tim, Büster, Lindsey, Carver, Sophie, Navarro, Laura Castells, Craig, Oliver E., Cook, Gordon T., Cunliffe, Barry, Denaire, Anthony, Dinwiddy, Kirsten Egging, Dodwell, Natasha, Ernée, Michal, Evans, Christopher, Kuchařík, Milan, Farré, Joan Francès, Fowler, Chris, Gazenbeek, Michiel, Pena, Rafael Garrido, Haber-Uriarte, María, Haduch, Elżbieta, Hey, Gill, Jowett, Nick, Knowles, Timothy, Massy, Ken, Pfrengle, Saskia, Lefranc, Philippe, Lemercier, Olivier, Lefebvre, Arnaud, Martínez, César Heras, Olmo, Virginia Galera, Ramírez, Ana Bastida, Maurandi, Joaquín Lomba, Majó, Tona, McKinley, Jacqueline I., McSweeney, Kathleen, Mende, Balázs Gusztáv, Modi, Alessandra, Kulcsár, Gabriella, Kiss, Viktória, Czene, András, Patay, Róbert, Endrődi, Anna, Köhler, Kitti, Hajdu, Tamás, Szeniczey, Tamás, Dani, János, Bernert, Zsolt, Hoole, Maya, Cheronet, Olivia, Keating, Denise, Velemínský, Petr, Dobeš, Miroslav, Candilio, Francesca, Brown, Fraser, Fernández, Raúl Flores, Herrero-Corral, Ana-Mercedes, Tusa, Sebastiano, Carnieri, Emiliano, Lentini, Luigi, Valenti, Antonella, Zanini, Alessandro, Waddington, Clive, Delibes, Germán, Guerra-Doce, Elisa, Neil, Benjamin, Brittain, Marcus, Luke, Mike, Mortimer, Richard, Desideri, Jocelyne, Besse, Marie, Brücken, Günter, Furmanek, Mirosław, Hałuszko, Agata, Mackiewicz, Maksym, Rapiński, Artur, Leach, Stephany, Soriano, Ignacio, Lillios, Katina T., Cardoso, João Luís, Pearson, Michael Parker, Włodarczak, Piotr, Price, T. Douglas, Prieto, Pilar, Rey, Pierre-Jérôme, Risch, Roberto, Rojo Guerra, Manuel A., Schmitt, Aurore, Serralongue, Joël, Silva, Ana Maria, Smrčka, Václav, Vergnaud, Luc, Zilhão, João, Caramelli, David, Higham, Thomas, Thomas, Mark G., Kennett, Douglas J., Fokkens, Harry, Heyd, Volker, Sheridan, Alison, Sjögren, Karl-Göran, Stockhammer, Philipp W., Krause, Johannes, Pinhasi, Ron, Haak, Wolfgang, Barnes, Ian, Lalueza-Fox, Carles, Reich, David
    Publicado 2018
    “…The forces propelling its expansion are a matter of long-standing debate, with support for both cultural diffusion and migration. …”
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    The Beaker Phenomenon and the Genomic Transformation of Northwest Europe
  19. 74399
    “…Exploratory analyses using subcortical white matter reference regions showed nonsignificant trends toward slower accumulation of plaque amyloid in the high-dose IV cohort. …”
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    Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in mild-to-moderate Alzheimer’s disease (BLAZE)
  20. 74400
    por Dahlberg, J, Andersson, G
    Publicado 2018
    “…The study underlines that in a society with low fertility and efficient birth control, active choices and behaviours associated with an individual’s sociodemographic characteristics tend to matter more for the seasonal timing of childbearing than environmental factors related to the physiological ability to reproduce and cultural–behavioural factors related to the frequency of intercourse. …”
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    Changing seasonal variation in births by sociodemographic factors: a population-based register study
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