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74701por De Santis, Stefano, Simone, Maria Domenica, Mercadante, Sebastiano, Mediati, Rocco Domenico, Vellucci, Renato, Marchetti, Paolo, Tonini, Giuseppe, Cuomo, Arturo, Caraceni, Augusto, Natoli, Silvia, Armento, Grazia, Blasi, Livio, Mammucari, Massimo“…However, pain management remains an unsolved matter, at least in the demanding oncology and palliative care setting. …”
Publicado 2021
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74702por Vela-Amieva, Marcela, Alcántara-Ortigoza, Miguel Angel, González-del Angel, Ariadna, Belmont-Martínez, Leticia, López-Candiani, Carlos, Ibarra-González, Isabel“…BACKGROUND: Glucose-6-phosphate dehydrogenase deficiency (G6PDd) newborn screening is still a matter of debate due to its highly heterogeneous birth prevalence and clinical expression, as well as, the lack of enough knowledge on its natural history. …”
Publicado 2021
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74703por Keshavan, Ashvini, Pannee, Josef, Karikari, Thomas K, Rodriguez, Juan Lantero, Ashton, Nicholas J, Nicholas, Jennifer M, Cash, David M, Coath, William, Lane, Christopher A, Parker, Thomas D, Lu, Kirsty, Buchanan, Sarah M, Keuss, Sarah E, James, Sarah-Naomi, Murray-Smith, Heidi, Wong, Andrew, Barnes, Anna, Dickson, John C, Heslegrave, Amanda, Portelius, Erik, Richards, Marcus, Fox, Nick C, Zetterberg, Henrik, Blennow, Kaj, Schott, Jonathan M“…We compared three different blood-based techniques—liquid chromatography-mass spectrometry measures of plasma amyloid-β, and single molecule array (Simoa) measures of plasma amyloid-β and phospho-tau181—to detect cortical (18)F-florbetapir amyloid PET positivity (defined as a standardized uptake value ratio of >0.61 between a predefined cortical region of interest and eroded subcortical white matter) in dementia-free members of Insight 46, a substudy of the population-based British 1946 birth cohort. …”
Publicado 2021
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74704por Toledo-Corral, C. M., Alderete, T. L., Herting, M. M., Habre, R., Peterson, A. K., Lurmann, F., Goran, M. I., Weigensberg, M. J., Gilliland, F. D.“…While causal models of HPA-axis dysregulation have been largely focused on either pre-existing health conditions or psychosocial stress factors, recent evidence suggests a possible role for central nervous system activation via air pollutants, such as nitrogen dioxide (NO(2)), ozone (O(3)) and particulate matter (PM). Therefore, in an observational study of Latino youth, we investigated if monthly ambient NO(2), O(3), and PM with aerodynamic diameter ≤ 2.5 (PM(2.5)) exposure were associated with morning serum cortisol levels. …”
Publicado 2021
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74705por Elser, Holly, Morello-Frosch, Rachel, Jacobson, Alice, Pressman, Alice, Kioumourtzoglou, Marianthi-Anna, Reimer, Richard, Casey, Joan A.“…Prior studies have found that short-term exposure to fine particulate matter (PM(2.5)), nitrogen dioxide (NO(2)), and ozone increases risk of migraine-related emergency department (ED) visits. …”
Publicado 2021
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74706por Mdege, Noreen Dadirai, Fairhurst, Caroline, Wang, Han-I, Ferdous, Tarana, Marshall, Anna-Marie, Hewitt, Catherine, Huque, Rumana, Jackson, Cath, Kellar, Ian, Parrott, Steve, Semple, Sean, Sheikh, Aziz, Wu, Qi, Azdi, Zunayed Al, Siddiqi, Kamran“…The primary outcome was the 24-h mean household airborne fine particulate matter (<2·5 microns in diameter [PM(2·5)]) concentration (a marker of second-hand smoke) at 12 months after randomisation. …”
Publicado 2021
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74707por Akerele, Mercy I., Zein, Sara A., Pandya, Sneha, Nikolopoulou, Anastasia, Gauthier, Susan A., Raj, Ashish, Henchcliffe, Claire, Mozley, P. David, Karakatsanis, Nicolas A., Gupta, Ajay, Babich, John, Nehmeh, Sadek A.“…The variability in the V(T) measured with PSAIF, in the test-retest study, was determined for selected brain regions (white matter, cerebellum, thalamus, caudate, putamen, pallidum, brainstem, hippocampus, and amygdala) using the Bland-Altman analysis and for each of the 3 normalization techniques. …”
Publicado 2021
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74708por Royse, Sarah K., Minhas, Davneet S., Lopresti, Brian J., Murphy, Alice, Ward, Tyler, Koeppe, Robert A., Bullich, Santiago, DeSanti, Susan, Jagust, William J., Landau, Susan M.“…With this pipeline, we derived SUVR-to-CL transformations using the Global Alzheimer’s Association Interactive Network data; we used reference regions for cross-sectional (whole cerebellum) and longitudinal (subcortical white matter, brain stem, whole cerebellum) analyses. Finally, we developed a FBB positivity threshold using an independent young control sample (N=62) with methods parallel to our existing FBP positivity threshold and validated the FBB threshold using a data-driven approach in ADNI participants (N=295). …”
Publicado 2021
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74709por van Marcke, C., Honoré, N., van der Elst, A., Beyaert, S., Derouane, F., Dumont, C., Aboubakar Nana, F., Baurain, J. F., Borbath, I., Collard, P., Cornélis, F., De Cuyper, A., Duhoux, F. P., Filleul, B., Galot, R., Gizzi, M., Mazzeo, F., Pieters, T., Seront, E., Sinapi, I., Van den Eynde, M., Whenham, N., Yombi, J. C., Scohy, A., van Maanen, A., Machiels, J. P.“…The safety of systemic anti-cancer therapy in oncology patients with non-severe COVID-19 is an important matter in daily practice. METHODS: ONCOSARS-1 was a single-center, academic observational study. …”
Publicado 2021
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74710por Oh, Han-Jin, Park, Yei-Ju, Cho, Jae Hyoung, Song, Min-Ho, Gu, Bon-Hee, Yun, Won, Lee, Ji-Hwan, An, Ji-Seon, Kim, Yong-Ju, Lee, Jun-Soeng, Kim, Sheena, Kim, Hyeri, Kim, Eun Sol, Lee, Byoung-Kon, Kim, Byeong-Woo, Kim, Hyeun Bum, Cho, Jin-Ho, Kim, Myung-Hoo“…The apparent total tract digestibility of dry matter and gross energy was the lowest in the CON group after one week. …”
Publicado 2021
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74711por Ross, Elizabeth G, Ball, Jase J, Werth, Samantha J, Mejia-Turcios, Sebastian E, Zhao, Yongjing, Pan, Yuee, Taube, Patrick C, Meinert, Todd R, Van Engen, Nicholas K, Mitloehner, F M“…Pens (n = 4 per treatment, 14 steers per pen, and 56 steers per treatment) were randomly assigned to one of two treatments: 1) CON; finishing ration containing no RAC, 2) RAC; finishing ration containing 27.3 g/907 kg dry matter (DM) basis RAC. Steers were weighed on day −1 and 0 before treatment and day 14, 28, and 42 during treatment. …”
Publicado 2021
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74712por Li, Cong, Yi, Chang, Chen, Yingshen, Xi, Shaoyan, Guo, Chengcheng, Yang, Qunying, Wang, Jian, Sai, Ke, Zhang, Ji, Ke, Chao, Chen, Fanfan, Lv, Yanchun, Zhang, Xiangsong, Chen, Zhongping“…The maximum and mean standardized uptake values (SUVmax and SUVmean) of the lesion and the lesion-to-normal grey-matter cortex uptake (L/G) ratio were obtained from each tracer PET/CT. …”
Publicado 2021
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74713por Patterson, William B., Glasson, Jessica, Naik, Noopur, Jones, Roshonda B., Berger, Paige K., Plows, Jasmine F., Minor, Hilary A., Lurmann, Frederick, Goran, Michael I., Alderete, Tanya L.“…METHODS: Residential exposure to AAP (particulate matter < 2.5 and 10 microns in aerodynamic diameter [PM(2.5), PM(10)]; nitrogen dioxide [NO(2)]; ozone [O(3)]; oxidative capacity [O(x)(wt): redox-weighted oxidative potential of O(3) and NO(2)]) was modeled by spatial interpolation of monitoring stations via an inverse distance-squared weighting (IDW2) algorithm for 123 participants from the longitudinal Mother’s Milk Study, an ongoing cohort of Hispanic mother-infant dyads from Southern California. …”
Publicado 2021
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74714por Mironova, Irina, Pleshkov, Alexey, Nigmatyanov, Azat, Yarmukhamedova, Elvira, Islamova, Sofia“…Milk quality analysis in the experimental groups indicated an increase in the dry matter content by 0.17-0.27% (p≤0.001) in summer and 0.16-0.27% (p≤0.001) in winter; higher protein levels by 0.04-0.06% in summer and 0.03-0.07% (p≤0.05) in winter; increased fat by 0.09-0.14% (p≤0.05-0.001) in summer and 0.09-0.13% (p≤0.05-0.001) in winter; increased density by 0.47-0.61°A (p≤0.05) in summer and 0.17-0.27°A in winter; and increased energy by 1.70-2.63% (p≤0.001) in summer and 1.57-2.54% (p≤0.01-0.001) in winter. …”
Publicado 2021
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74715por Kabootari, Maryam, Asgari, Samaneh, Ghavam, Seyedeh Maryam, Abdi, Hengameh, Azizi, Fereidoun, Hadaegh, Farzad“…BACKGROUND: Fasting plasma glucose (FPG) and 2-h post challenge plasma glucose (2 h-PCPG), whether as continuous or categorical variables, are associated with incident cardiovascular disease (CVD) and diabetes; however, their role among patients with existing CVD is a matter of debate. We aimed to evaluate associations of different glucose intolerance states with recurrent CVD and incident diabetes among subjects with previous CVD. …”
Publicado 2021
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74716por Lipton, Richard B., Dodick, David W., Ailani, Jessica, McGill, Lora, Hirman, Joe, Cady, Roger“…Collectively, these results indicate that PI‐MBS is a promising and novel outcome measure for preventive trials of CM and thus may provide a unique patient‐centered approach for identifying and measuring the burden of migraine symptoms that matter most to each patient, as well as the benefits of treatment.…”
Publicado 2021
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74717por Enkhbat, Undarmaa, Gombojav, Enkhjargal, Banzrai, Chimeglkham, Batsukh, Sarangerel, Boldbaatar, Buyantushig, Enkhtuya, Enkhtuul, Ochir, Chimedsuren, Bellinger, David C., Lanphear, Bruce P., McCandless, Lawrence C., Allen, Ryan W.“…BACKGROUND: Developmental exposure to particulate matter (PM) air pollution may impair children’s behaviors. …”
Publicado 2021
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74718por Bejanin, Alexandre, Iulita, Maria Florencia, Vilaplana, Eduard, Carmona-Iragui, Maria, Benejam, Bessy, Videla, Laura, Barroeta, Isabel, Fernandez, Susana, Altuna, Miren, Pegueroles, Jordi, Montal, Victor, Valldeneu, Silvia, Giménez, Sandra, González-Ortiz, Sofía, Muñoz, Laia, Padilla, Concepción, Aranha, Mateus Rozalem, Estellés, Teresa, Illán-Gala, Ignacio, Belbin, Olivia, Camacho, Valle, Wilson, Liam Reese, Annus, Tiina, Osorio, Ricardo S., Videla, Sebastián, Lehmann, Sylvain, Holland, Anthony J., Zetterberg, Henrik, Blennow, Kaj, Alcolea, Daniel, Clarimon, Jordi, Zaman, Shahid H., Blesa, Rafael, Lleó, Alberto, Fortea, Juan“…Voxelwise analyses were performed to assess topographical differences in gray matter metabolism and volume. RESULTS: Of the 464 adults with DS included in the study, 97 (20.9%) were APOE ɛ4 allele carriers and 367 (79.1%) were noncarriers. …”
Publicado 2021
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74719por Bonaventura, Eleonora, Barone, Rita, Sturiale, Luisa, Pasquariello, Rosa, Alessandrì, Maria Grazia, Pinto, Anna Maria, Renieri, Alessandra, Panteghini, Celeste, Garavaglia, Barbara, Cioni, Giovanni, Battini, Roberta“…Neuroimaging showed a Leigh syndrome-like pattern involving the basal ganglia, thalami and white matter. In the two siblings, atrophic cerebral and cerebellum changes consistent with SLC39A8-CDG were detected as well. …”
Publicado 2021
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74720por Xie, Sherrie, Meeker, Jessica R., Perez, Luzmercy, Eriksen, Whitney, Localio, Anna, Park, Hami, Jen, Alicia, Goldstein, Madison, Temeng, Akua F., Morales, Sarai M., Christie, Colin, Greenblatt, Rebecca E., Barg, Frances K., Apter, Andrea J., Himes, Blanca E.“…BACKGROUND: Exposure to fine particulate matter (PM(2.5)) increases the risk of asthma exacerbations, and thus, monitoring personal exposure to PM(2.5) may aid in disease self-management. …”
Publicado 2021
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