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241“…Desmoplastic melanoma (DM) and spindle cell melanoma (SCM) are 2 rare subtypes of melanoma. …”
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242por Fechete, Oana, Ungureanu, Loredana, Șenilă, Simona, Vornicescu, Daniela, Dănescu, Sorina, Vasilovici, Alina, Candrea, Elisabeta, Vesa, Ștefan cristian, Cosgarea, Rodica“…In contrast to Western Europe, in Central and Eastern Europe reports show higher rates of advanced melanoma and lower survival. Our aim was to document and compare melanoma risk factors and skin health behaviour in patients diagnosed with melanoma and people not affected by this disease in a large medical university centre from Romania (Cluj-Napoca). …”
Publicado 2019
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243por Kappelmann-Fenzl, Melanie, Gebhard, Claudia, Matthies, Alexander O., Kuphal, Silke, Rehli, Michael, Bosserhoff, Anja Katrin“…Here we mapped the genome-wide occupancy of the AP-1 family member c-Jun in different melanoma cells and correlated AP-1 binding with transcriptome data to detect genes in melanoma regulated by c-Jun. …”
Publicado 2019
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244por Rahman, Md. Mahfuzur, Lai, Yu-Chang, Husna, Al Asmaul, Chen, Hui-Wen, Tanaka, Yuiko, Kawaguchi, Hiroaki, Hatai, Hitoshi, Miyoshi, Noriaki, Nakagawa, Takayuki, Fukushima, Ryuji, Miura, Naoki“…Dogs have been considered as an excellent immunocompetent model for human melanoma due to the same tumor location and the common clinical and pathological features with human melanoma. …”
Publicado 2020
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245por Yue, Yuyang, Liu, Lijuan, Liu, Peipei, Li, Yuting, Lu, Haitao, Li, Yanjia, Zhang, Guoqiang, Duan, Xinsuo“…The effects of cardamonin on melanoma cells are unknown. The present study investigated the anti-proliferative effect of cardamonin on human melanoma cell lines (M14 and A375), and the underlying apoptosis inducing mechanisms. …”
Publicado 2020
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246por Pradhan, Dinesh, Jour, George, Milton, Denái, Vasudevaraja, Varshini, Tetzlaff, Michael T., Nagarajan, Priyadharsini, Curry, Jonathan L., Ivan, Doina, Long, Lihong, Ding, Yingwen, Ezhilarasan, Ravesanker, Sulman, Erik P., Diab, Adi, Hwu, Wen-Jen, Prieto, Victor G., Torres-Cabala, Carlos Antonio, Aung, Phyu P.“…Acral melanoma (AM) is a rare, aggressive type of cutaneous melanoma (CM) with a distinct genetic profile. …”
Publicado 2019
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247“…Background: BRCA1-Associated Protein 1 (BAP1) germline mutations predispose individuals to cancers, including uveal melanoma (UM) and cutaneous melanoma (CM). BAP1 loss is common in UM and is associated with a worse prognosis. …”
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248“…Melanoma is a highly aggressive cancer, attracting increasing attention worldwide. …”
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249“…Malignant melanoma is a highly malignant tumor originating from the melanocytes of the neural crest, which is prone to metastasis and has a poor prognosis. …”
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250por Simonetti, Oriana, Molinelli, Elisa, Brisigotti, Valerio, Brancorsini, Donatella, Talevi, Davide, Offidani, Annamaria“…Primary dermal melanoma (PDM) is a rare distinct variant of cutaneous melanoma, predominantly occurring on the extremities of young or middle-aged adults. …”
Publicado 2021
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251por Millán-Esteban, David, Peña-Chilet, María, García-Casado, Zaida, Manrique-Silva, Esperanza, Requena, Celia, Bañuls, José, López-Guerrero, Jose Antonio, Rodríguez-Hernández, Aranzazu, Traves, Víctor, Dopazo, Joaquín, Virós, Amaya, Kumar, Rajiv, Nagore, Eduardo“…We conducted a retrospective study to examine whether this model had a molecular support using sequencing and bioinformatic tools on a set of cutaneous melanomas corresponding to these two groups. We found that the nevogenic melanomas were associated with mutations in BRAF, while the CSD melanomas were associated with mutations in NF1, ROS1, GNA11, and RAC1. …”
Publicado 2021
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252Clinical Study on the Increased Incidence of Nodular Melanoma Cases Compared to Superficial Melanomapor ANGHEL-SAVCIU, RUMI-EUGEN, RĂDULESCU, CICERONE, DOBRE, CRISTIANA, CIUREA, MARIUS EUGEN, CIUREA, ANA MARIA, ANGHEL-SAVCIU, NICOLETA-LOREDANA, VRABETE, MARIA“…Our study group was comprised of 67 patients with melanoma, admitted and operated in our clinic between 2010-2018. …”
Publicado 2021
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253por Immonen, Anni, Haapasaari, Kirsi-Maria, Skarp, Sini, Karihtala, Peeter, Teppo, Hanna-Riikka“…We characterized the immunohistochemical expression of NRF3 in 81 naevi, 67 primary skin melanomas, and 51 lymph node metastases. The immunohistochemical expression of cytoplasmic NRF3 decreased from benign to dysplastic naevi (p < 0.001) and further to primary melanomas (p < 0.001). …”
Publicado 2022
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254por Fujimura, Taku“…Immune checkpoint inhibitors (ICIs), such as anti-programmed cell death 1 (PD1) antibodies (Abs) and anti-cytotoxic T-lymphocyte associated protein 4 (CTLA4) Abs, have been widely administered for not only advanced melanoma, but also various non-melanoma skin cancers. …”
Publicado 2022
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255“…Recent advances in treating cutaneous melanoma have resulted in impressive patient survival gains. …”
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256por Rubatto, Marco, Sciamarrelli, Nadia, Borriello, Silvia, Pala, Valentina, Mastorino, Luca, Tonella, Luca, Ribero, Simone, Quaglino, Pietro“…Advanced melanoma and non-melanoma skin cancers (NMSCs) are burdened with a dismal prognosis. …”
Publicado 2023
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257por Rauwerdink, Daan Jan Willem, van Doorn, Remco, van der Hage, Jos, Van den Eertwegh, Alfonsus J. M., Haanen, John B. A. G., Aarts, Maureen, Berkmortel, Franchette, Blank, Christian U., Boers-Sonderen, Marye J., De Groot, Jan Willem B., Hospers, Geke A. P., de Meza, Melissa, Piersma, Djura, Van Rijn, Rozemarijn S., Stevense, Marion, Van der Veldt, Astrid, Vreugdenhil, Gerard, Wouters, Michel W. J. M., Suijkerbuijk, Karijn, van der Kooij, Monique, Kapiteijn, Ellen“…SIMPLE SUMMARY: Nodular melanoma is associated with a higher locoregional recurrence rate and worse overall survival outcomes. …”
Publicado 2022
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258“…Interferons (IFNs) have demonstrated therapeutic potential in various skin cancers, specifically squamous cell carcinoma (SCC), basal cell carcinoma (BCC), and melanoma. The precise mechanism through which type I IFNs exert their antitumor effects in skin cancers is still being studied. …”
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259Case Report: Dynamic overlap of melanoma, sarcoidosis, and targeted therapy for BRAF-mutant melanoma“…Targeted therapies, including BRAF and MEK inhibitors, are valuable treatment options for patients with unresectable or metastatic BRAF V600-mutant melanoma. With the improvement in survival seen with modern melanoma therapeutics, clinicians are learning the variable patterns associated with extended clinical courses. …”
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260por Gallagher, R. P., Elwood, J. M., Hill, G. B., Coldman, A. J., Threlfall, W. J., Spinelli, J. J.“…A study of 361 female melanoma patients and age matched controls was conducted in the four western provinces of Canada. …”
Publicado 1985
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