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261“…Clinical-pathologic-genetic studies were performed on 3 kindreds showing the familial atypical multiple mole-melanoma syndrome (FAMMM). Findings showed vertical transmission, including father-to-son, of cutaneous malignant melanoma and/or FAMMM moles with no sex predilection. …”
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263por Zhou, Jun, Yuen, Noah K., Zhan, Qian, Velazquez, Elsa F., Murphy, George F., Giobbie-Hurder, Anita, Hodi, F. Stephen“…Therapeutic targeting of melanoma antigens frequently focuses on the melanocyte differentiation or cancer-testis families. …”
Publicado 2011
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264por Tozum, Halil, Ozkan, Korhan, Reddy, Krishna, Turkmen, Ismail, Ciloglu, Ufuk, Senol, Serkan, Graci, Calogero“…Solitary metastasis of uveal melanoma to bone is extremely rare and usually associated with other organ involvement. …”
Publicado 2013
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265“…The ILI technique was developed at the Sydney Melanoma Unit (now renamed the Melanoma Institute Australia), and only a few other centers have reported separate results. …”
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266por CHENG, FANG, HE, RUNZHI, ZHANG, LEI, LI, HUI, ZHANG, WEI, JI, XIAOLIN, KONG, FANTING, SUN, JIANFANG, CHEN, SHUBO“…In our previous study, an increase in neddylation was identified in melanoma cell lines. In the present study, the upregulation of neddylation was detected in melanoma tissues which confirmed the results of our previous study on melanoma cell lines. …”
Publicado 2014
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267Neuropilin-1 expressing melanoma cells as a model to study the aggressiveness of metastatic melanomapor Ruffini, Federica, Graziani, Grazia, Levati, Lauretta, Tentori, Lucio, Caporali, Simona, D’Atri, Stefania, Lacal, Pedro MEnlace del recurso
Publicado 2015
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268por de Araújo, Érica S. S., Pramio, Dimitrius T., Kashiwabara, André Y., Pennacchi, Paula C., Maria-Engler, Silvya S., Achatz, Maria I., Campos, Antonio H. J. F. M., Duprat, João P., Rosenberg, Carla, Carraro, Dirce M., Krepischi, Ana C. V.“…In melanoma development, oncogenic process is mediated by genetic and epigenetic mutations, and few studies have so far explored the role of DNA methylation either as predisposition factor or biomarker. …”
Publicado 2015
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269por LU, JING, CHENG, YABIN, ZHANG, GUOHONG, TANG, YUN, DONG, ZIMING, MCELWEE, KEVIN J, LI, GANG“…However, the function of NRP1 in melanoma progression, as well as the effect of NRP1 expression on the prognosis of patients with melanoma remains unknown. …”
Publicado 2015
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270“…INTRODUCTION: Melanoma is the most deadly type of skin cancer with 75% of all skin cancer deaths within the US attributed to it. …”
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271“…Metastatic melanoma patients have a poor prognosis, mainly attributable to the underlying heterogeneity in melanoma driver genes and altered gene expression profiles. …”
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272“…Increased or decreased expression of LIF receptor (LIFr) has been reported in several human cancers, including skin cancer, but its role in melanoma is unknown. In this study, we investigated the expression pattern of LIFr in melanoma and assessed its prognostic value. …”
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273“…This paper provides consensus recommendations on the management of melanomas arising in the skin and mucosa of the head and neck region on the basis of current evidence. …”
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274por Lazova, Rossitza, Pornputtapong, Natapol, Halaban, Ruth, Bosenberg, Marcus, Bai, Yalai, Chai, Hao, Krauthammer, Michael“…We performed exome-sequencing of 77 melanocytic specimens composed of Spitz nevi (n=29), Spitzoid melanomas (n=27) and benign melanocytic nevi (n=21), and compared the results to published melanoma sequencing data. …”
Publicado 2017
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275“…She had a history of total removal of malignant melanoma on the left eye ball 20 years prior. No evaluation had been performed since then. …”
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276por Nieder, Carsten, Hintz, Mandy, Bilger, Angelika, Oehlke, Oliver, Grosu, Anca-Ligia“…BACKGROUND: It has been suggested to replace the diagnosis-specific graded prognostic assessment (DS-GPA, based on performance status and number of brain metastases) for patients with primary malignant melanoma with the new Melanoma-molGPA. The latter is a more complex assessment, which also includes BRAF mutation status, age and extracranial metastases. …”
Publicado 2018
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277por Sharma, Priyanka, Ludwig, Sonja, Muller, Laurent, Hong, Chang Sook, Kirkwood, John M, Ferrone, Soldano, Whiteside, Theresa L.“…The role of this exosome subset in melanoma progression has been of interest ever since ex vivo studies of exosomes produced by melanoma cell lines were shown to suppress anti-melanoma immune responses. …”
Publicado 2018
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278“…BACKGROUND: Melanoma appears to be a malignant disease, whose development can be potentiated by different drug groups. …”
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279por Paolino, Giovanni, Rizzo, Nathalie, Pampena, Riccardo, Bearzi, Pietro, Bulotta, Alessandra, Gregorc, Vanesa, Brianti, Pina, Moliterni, Elisa, Mercuri, Santo RaffaeleEnlace del recurso
Publicado 2020
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280por In, Gino K., Poorman, Kelsey, Saul, Michelle, O’Day, Steven, Farma, Jeffrey M., Olszanski, Anthony J., Gordon, Michael S., Thomas, Jacob S., Eisenberg, Burton, Flaherty, Lawrence, Weise, Amy, Daveluy, Steven, Gibney, Geoffrey, Atkins, Michael B., Vanderwalde, Ari“…Background: Brain metastases are a significant cause of mortality and morbidity for patients with melanoma. We hypothesize that the development of brain metastases may be explained by molecular heterogeneity between primary cutaneous melanoma (PCM) or extracranial (ECM) and brain (MBM) melanoma metastases. …”
Publicado 2020
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