“…We report a case of an extremely rare primary malignant melanoma presenting in the retroperitomeum, indurcing a diagnostic and management problem.…”
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“…BACKGROUND: In melanoma, radiotherapy has generally been considered as a palliative treatment option indicated only for advanced cases or disseminated disease. …”
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“…The anorectum is a rare anatomic location for primary melanoma. Mucosal melanoma is a distinct biological and clinical entity from the more common cutaneous melanoma. …”
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“…In a recent study, we revealed how natural killer (NK) cells can participate in such an immunoediting process, by rendering melanoma cells resistant to NK-mediated killing.…”
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“…Ipilimumab is a monoclonal antibody directed against cytotoxic T-lymphocyte antigen-4 that has been approved by the US Food and Drug Administration for the treatment of metastatic melanoma. Phase III trials have demonstrated an overall survival benefit with its use when compared with standard treatments and other investigational therapies. …”
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“…BACKGROUND: Melanoma is the most serious skin cancer. There is an established correlation between thickness and aggressiveness of the tumor. …”
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“…In vivo, we used the HGF transgenic mouse model of UV-induced melanoma to demonstrate that topical treatment with l-selenomethionine results in a significant delay in the time required for UV-induced melanoma development, but also increases the rate of growth of those tumors once they appear. …”
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“…Metastatic malignant melanoma of the prostate is extremely rare in clinical practice, and only one case has been reported in the English literature in the past 30 years. …”
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“…Primary malignant melanoma of the esophagus (PMME) comprises only 0.1–0.2% of all malignant esophageal tumors. …”
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“…A review of the natural behavior of cutaneous melanoma, clinical and pathological factors, prognostic indicators, some basic research and the present and possible futuristic strategies in the management of this disease are presented. …”
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“…EGT with IL-12 is in melanoma clinical trials and nsPEFs are used in models with B16F10 melanoma in vitro and in mice. …”
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“…We describe the dermatoscopy of acral metastatic amelanotic melanoma.…”
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“…Primary pineal malignant melanoma is a rare entity, with only thirteen cases reported in the world literature to date. …”
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“…Spontaneous rupture of spleen due to malignant melanoma is a rare situation, with only a few case reports in the literature. …”
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“…We describe a case of melanoma with the presence of comedo-like openings at dermoscopy. …”
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“…This review aims to summarize the current knowledge of molecular pathways and their clinical relevance in melanoma. Metastatic melanoma was a grim diagnosis, but in recent years tremendous advances have been made in treatments. …”
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“…Nowadays, new effective treatment options with biological agents justify the closer monitoring of high risk melanoma patients.…”
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